Publications

  1. Cervantes JL, Hawley KL, Benjamin SJ, Weinerman B, Luu SM, Salazar JC. Phagosomal TLR signaling upon Borrelia burgdorferi infection. Front Cell Infect Microbiol. 2014 May 20;4:55.
  2. Libardo MD, Cervantes JL, Salazar JC, Angeles-Boza AM. Improved Bioactivity of Antimicrobial Peptides by Addition of Amino-Terminal Copper and Nickel (ATCUN) Binding Motifs. Chem Med Chem. 2014 Aug;9(8):1892-901.
  3. Salazar JC, Cahn P, Della Negra M, De Aquino MZ, Robinson PA, Jelaska A, Mikl J. Efficacy and safety of tipranavir coadministered with ritonavir in HIV-1-infected children and adolescents: 5 years of experience. Pediatr InfectDis J. 2014 Apr;33(4):396-400.
  4. Cruz AR, Castrillón MA, Minotta AY, Rubiano LC, Castaño MC, Salazar JC. Gestational and congenital syphilis epidemic in the colombian pacific coast Sex Transm Dis. 2013 Oct;40(10):813-8.
  5. Salazar JC, Cahn P, Negra MD, De Aquino MZ, Robinson PA, Jelaska A, Mikl J. Efficacy and Safety of Tipranavir Co-Administered with Ritonavir in HIV-1-Infected Children and Adolescents: 5 Years of Experience. Pediatr Infect Dis J. 2013 Aug 29.
  6. Silver AC, Dunne DW, Zeiss CJ, Bockenstedt LK, Radolf JD, Salazar JC, Fikrig E. MyD88 Deficiency Markedly Worsens Tissue Inflammation and Bacterial Clearance in mice Infected with Treponema pallidum, the Agent of Syphilis. PLoS One. 2013 Aug 5;8(8):e71388.
  7. Cervantes JL, La Vake CJ, Weinerman B, Luu S, O'Connell C, Verardi PH, Salazar JC*.Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes.  J Leukoc Biol. 2013 Aug 1.
  8. Clark RB, Cervantes JL, Maciejewski MW, Farrokhi V, Nemati R, Yao X, Anstadt E, Fujiwara M, Wright KT, Riddle C, La Vake CJ, Salazar JC, Finegold S, Nichols FC. Serine lipids of Porphyromonas gingivalis are human and mouse Toll-like receptor 2 ligands. Infect Immun. 2013 Jul 8.
  9. Cervantes JL, Weinerman B, Basole C and Salazar JC*.    TLR8: The forgotten relative revindicated, Accepted for publication in Cellular & Molecular Immunology (Nature publishing group), 2012 Nov;9(6):434-8. doi: 10.1038/cmi.2012.38.
  10. Cruz AR, Ramirez LG, Zuluaga AV, Pillay A, Abreu C, Valencia CA, La Vake C, Cervantes JL, Dunham-Ems S, Cartun R, Mavilio D, Radolf JD and Salazar JC*. Immune Evasion and Recognition of the Syphilis Spirochete in Blood and Skin of Secondary Syphilis Patients: Two Immunologically Distinct Compartments, PLoS Negl Trop Dis, July 18, 2012.
  11. Roehm CE, Salazar JC, Hagstrom and Valdez TA. Phoma and Acremonium invasive fungal rhinosinusitis in congenital acute lymphocytic leukemia and literature review. International Journal of Pediatric Otorhinolaryngology.   2012 Oct;76(10):1387-91
  12. Anand A, Luthra A, Dunham-Ems S, Caimano M, Karanian C, LeDoyt M, Cruz AR, Salazar JC, and Radolf JD. TprC/D (Tp0117/131), a trimeric, pore-forming rare outer membrane protein of Treponema pallidum, has a bipartite domain structure". Journal of Bacteriology, 2012.
  13. KL Hawley, CM Olson, Jr, N Navasa, JM Iglesias-Pedraz, JL Cervantes, MJ Caimano, H Izadi, R Ingalls, U Pal, JC Salazar, JD Radolf, J Anguita. CD14 Cooperates with Complement Receptor 3 to Mediate MyD88-Independent Phagocytosis of Borrelia burgdorferi. Proc Natl Acad Sci USA. Jan, 2012.
  14. Desrosiers DC, Anand A, Luthra A, Dunham-Ems SM, Ledoyt M, Cummings MA, Eshghi A, Cameron CE, Cruz AR, Salazar JC, Caimano MJ, Radolf JD. TP0326, a Treponema pallidum β-Barrel Assembly Machinery A (BamA) Ortholog and Rare Outer Membrane Protein. Mol Microbiol. 2011 Apr 14 .
  15. Stojanov S, Lapidus S, Chitkara P, Feder H, Salazar JC, Fleisher TA, Brown MR, Edwards KM, Ward MM, Colbert RA, Sun HW, Wood GM, Barham BK, Jones A, Aksentijevich I, Goldbach-Mansky R, Athreya B, Barron KS, Kastner DL. PFAPA syndrome is a disorder of innate immune regulation and Th1 activation responsive to IL-1 blockade. Proc Natl Acad Sci U S A. 2011 Apr 8. .
  16. Cervantes JL, Dunham-Ems SM, La Vake CJ, Petzke MM, Sahay B, Sellati TJ, Radolf JD, Salazar JC*. Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β. Proc Natl Acad Sci. 2011 Mar 1;108(9):3683-8. Epub 2011 Feb 14
  17. Courter JD, Teevan CJ, Li MH, Girotto JE and Salazar JC*. Role of tipranavir in treatment of patients with multidrug-resistant HIV.Therapeutics and Clinical Risk Management. 2010;6  431-441.
  18. Cox DL, Luthra A, Dunham-Ems S, Desrosiers DC, Salazar JC, Caimano MJ, Radolf JD. Surface immunolabeling and consensus computational framework to identify candidate rare outer membrane proteins of Treponema pallidum. Infect Immun. 2010 Sep 27. 
  19. Desrosiers DC, Bearden SW, Mier I Jr, Abney J, Paulley JT, Fetherston JD, Salazar JC, Radolf JD, Perry RD. Znu is the predominant zinc importer in Yersinia pestis during in vitro growth but is not essential for virulence. Infect Immun. 2010 Sep 20. 
  20. Deville JG, Goldfarb J, Kaplan SL, Equils O, Huang DB, Ang JY, Salazar JC*. The use of linezolid in the treatment of paediatric patients with infections caused by enterococci including strains resistant to vancomycin. J Antimicrob Chemother. 2010 Oct;65(10):2267-70. Epub 2010 Aug 12..
  21. Cruz AR, Pillay A, Zuluaga AV, Ramirez LG, Duque JE, Aristizabal GE, Fiel-Gan MD,Jaramillo R, Trujillo R, Valencia C, Jagodzinski L, Cox DL, Radolf JD, Salazar JC*. Secondary syphilis in Cali, Colombia: New concepts in disease pathogenesis. PLoS Negl Trop Dis. 2010 May 18;4(5):e690
  22. Courter JD; Girotto JE, Lobato MN, Orcutt D; Burke M, Feder HM; Krause PJ, Cohen-Abbo A, Salazar JC*. Intravenous streptomycin treatment for treatment of Mycobacterium tuberculosis meningitis in an infant.  Pharmacotherapy, 2010;30(11):1197.
  23. Feder Jr. HM and Salazar JC. A clinical review of 105 patients with PFAPA (A periodic fever syndrome).  Acta Pediatrica, 2010 Feb;99(2):178-84.
  24. Kanev  P,  Salazar  JC.  Unusual  CNS  infection  from  a  subtorcular  dermal  sinus. Acta Paediatr. 2010 Apr;99(4):627-9
  25. Sahay B, Patsey RL, Eggers CH, Salazar JC, Radolf JD, Sellati TJ. CD14 signaling restrains chronic inflammation through induction of p38-MAPK/SOCS-dependent tolerance. PLoS Pathog. 2009 Dec;5(12):e1000687.
  26. Lomotey CL, Lewis J, Gebrian B, Bourdeau R, Dickhaus K, Salazar JC*. Maternal and Congenital Syphilis in Rural Haiti.  Pan Am J Public Health, 26(3), 197-202, 2009.
  27. Salazar JC*, Duhnam-Ems S, LaVake CJ, et al. Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-beta. PLoS Pathog 2009 May; 5(5):e1000444.
  28. Salazar JC*, Cahn P, Yogev R, Della Negra M, Castelli-Gattinara G, Fortuny C, Flynn P, Giaquinto C, Capparelli EV, Fenton T, MIkl J, Jelaska A, for the PACTG 1051/BI study team. Efficacy, safety and tolerability of tipranavir coadministered with ritonavir in HIV-1- infected children and adolescents.  AIDS, 22: 2008
  29. Courter J, Girotto J, Salazar JC*, Tipranavir a new protease inhibitor for the pediatric population.  Expert Rev Anti Infect Ther. 2008 Dec;6(6):797-803.
  30. Cruz AR, Moore MW, LaVake CJ, Eggers CH, Salazar JC, Radolf JD. Phagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates immune activation and induces apoptosis in human monocytes.  Infection and Immunity, 76(1):56-70, 2008
  31. St. Germain RM, Sevket Y, Wells L, Ellis JM, Salazar JC. Cushing syndrome and severe adrenal suppression caused by fluticasone and protease inhibitor combination in an HIV infected adolescent.  AIDS Patient Care and STDs, 21(6), 373-77, 2007.
  32. Salazar JC, Rathi A, Michael NL, Radolf, JD, Jagodzinski LL. Assessment of the Kinetics of Treponema pallidum Dissemination into Blood and Tissues in Experimental Syphilis by Real-Time Quantitative PCR. Infection and Immunity, 75(6), 2954-2958, 2007.
  33. Ellis JM, Rivera L, Reyes G, Castillo F, Castillo P, Tejada M and Salazar JC*. Cefepime Cerebrospinal Concentrations in Neonatal Bacterial Meningitis. The Annals of Pharmacotherapy, 41(7), 900-901, 2007
  34. Moore, MW, Cruz, AR, LaVake, CJ, Marzo, AL, Eggers, CH, Salazar, JC, and Radolf, JD, Phagocytosis of Borrelia burgdorferi and Treponema pallidum potentiates innate immune activation and induces IFN-production. Infection and Immunity, 2007 Apr; 75(4):2046-62.
  35. Salazar JC*, Cruz A, Pope C, Valderrama L, Trujillo R, Saravia NG, and Radolf JD. Treponema pallidum elicits Innate and Adaptive Cellular Immune Responses in Skin and Blood during Secondary Syphilis: A Flow Cytometric Analysis.  JID, 2007; 195(6):879-87
  36. Raju M, Salazar JC*, Leopold H, and Krause PJ. Atovaquone and Azithromycin Treatment for Babesiosis in an Infant. Pediatr Infect Dis J. 2007 Feb; 26(2):181-183.
  37. Smith-Slatas C, Bourque MD, and Salazar JC*. Clostridium septicum Infections in Children: A Case Report and Review of the Literature. Experience and Reason. Pediatrics. 117(4), e796-e805, 2006.
  38. Salazar JC*, Pope CD, Moore MW, Pope J, Kiely TG and Radolf JD. Lipoprotein- dependent and -independent immune response to spirochetal infection. Clin. Diag. Lab. Immunol. 12, 949-958, 2005.
  39. Berrien VM, Salazar JC*, Reynolds E. and McKay K. Adherence to  Antiretroviral Therapy in HIV-Infected Pediatric Patients Improves with Home-Based Intensive Nursing Intervention.  AIDS Patient Care and STDs. 2004, 18(6):355-364.
  40. Ellis JM, Reilly JC, and Salazar JC. Influenza vaccination for the pediatric patient: A focus on the new intranasal, cold-adapted, live attenuated vaccine. J Pediatr Pharmacol Ther, 2004, 9(2), 104-109.
  41. Salazar JC*. Pediatric Clinical Trial Experience: Government, Child, Parent and Physician’s Perspective, Pediatr Infect Dis J.  2003;22(12):1124-1127.
  42. Salazar JC*, Pope CD, Sellati TJ, Feder HM, Kiely TG, Dardick KR, Buckman RL, Moore MW, Caimano MJ, Pope JG, Krause PJ, Radolf JR and The Lyme Disease Network.  Co- evolution of Innate and Adaptive Immunity in Skin and Peripheral Blood of Patients with Erythema Migrans. J Immunology, 2003, 171:2660-2670.
  43. Feder HM, Roberts JC, Salazar JC, Leopold HB, Toro-Salazar O. HACEK Endocarditis in Infants  and  Children:  Two  Cases  and  Review  of  the  Literature.        Pediatr Infect Dis J, 22(6):557-562, 2003.
  44. Acosta-Glynn C, Fernandez NL, Neal R, and Salazar J*. Hartford Youth HIV Identification and Linkage to Care (H.Y.H.I.L.) XIV International AIDS Conference. Extended Abstract C708S8854, Moduzzi Editore S.p.A. 97-101, 2002.
  45. Zervas SJ, Zemel LS, Romness MJ, Kaplan EL and Salazar JC*.  Streptococcus pyogenes pyomyositis. Pediatr Infect Dis J. 21:166-168 2002.
  46. Sellati TJ, Waldrop SL, Salazar, JC, Bergstresser PR, Picker LJ, and Radolf JD. The cutaneous response in humans to Treponema pallidum lipoprotein analogues involves cellular elements of both innate and adaptive immunity, J Immunol, 166:4131-4140, 2001
  47. Crespo MP, Velez JD, Castañeda CR, Hoyos F, Lopez ML, and Salazar JC. Aislamiento de Listeria monocytogenes en un hospital de tercer nivel. Colombia Médica. Vol 30 (2), 89-98, 1999.
  48. Pfaller MA, Jones RN, Doern GV, Salazar JC.Multicenter evaluation of antimicrobial resistance to six broad-spectrum beta lactams in Colombia: comparison of data from 1997 and 1998 using the Etest method. The Colombian Antimicrobial Comparison Resistance Study Group.  Diagn Microbiol Infect Dis. 35(3): 235-241, 1999
  49. Jones RA, Salazar JC, Pfaller MA and Doern GV. Multi-Center evaluation of antimicrobial resistance to six broad-spectrum B-lactams in Colombia using the Etest method.Diagn Microbiol Infect Dis, 29, 1-8, 1997.
  50. Salazar JC, Daly KA, Giebink GS, Lindgren BR, Liebeler CL, Meland M, and Le CT. Low cord blood pneumococcal Inmunoglobulin G (IgG) antibodies predict early onset otitis media in infancy. American Journal of Epidemiology, 145(11), 1048-1056, 1997.
  51. Salazar JC, Bloom KE, Hostetter MK, Leonardi CL. Drug resistant tuberculosis verrucosa cutis in a South East Asian teenager. Pediatric Infectious Diseases Journal 15(9), 834-836, 1996.
  52. Salazar JC*, Londoño LJ, Liebeler C, Trujillo F, Meier J, and Giebink GS. Pneumococcal seroepidemiologic study of Colombian and Minnesota children. Pediatric Infectious Diseases Journal. 14(11): 1001-1003.  1995
  53. Salazar JC, and Ferrieri PF. Review of the new guidelines for the diagnosis of rheumatic fever.  Infections in Medicine, 11(11): 717-722, 1994.
  54. Salazar JC, Toro-Salazar OH, and Kaplan EL: Infective endocarditis in children, "An evaluation at the close of the twentieth century". Intercontinental Cardiology, 2(1): 7-15, 1993
  55. Salazar JC, Gerber MA, and Goff CW: Long-term outcome of Lyme disease in children given early treatment. Journal of Pediatrics; 122(4): 591-593, 1993.

Non Peer Reviewed Publications

  1. Cohen-Abbo A, Salazar JC. Summer Rash (Measles). Conn Med. 2013 Jun-Jul;77(6):381
  2. Salazar JC, Hazlett KRO, Radolf JR. The immune response to infection with Treponema pallidum, the    stealth pathogen. Microbes and Infection, 4 (11), 1133-1140, 2002.
  3. Rincón HG, Salazar JC, Congote A.   El consentimiento informado en la Fundación Clínica Valle del Lili.  Colombia Médica.  Vol 30 (2), 99-101, 1999.
  4. Salazar JC*.  Uso de corticoides en meningitis bacteriana (Editorial).  Infectio (Journal of the Colombian Infectious Diseases Association), 2(1), 2, 1998.
  5. Rosso F, Velez JD, Salazar JC, Lopez P, Corral R, Villegas MV, Muñoz J. Guía para el manejo de dengue  y sus complicaciones. Boletín, Servicio Integrado de Enfermedades Infecciosas (SIEI), 4(1), 20-22, 1998

Books And Book Chapters

  1. Salazar JC*. Neurosyphilis, Chapter 4 in Neurosyphilis a Clinical Approach.  Juan Carlos Garcia Monco, Elsevier, pp 227-247, 07 May 2014
  2. Radolf JD and Salazar JC, Venereal Syphilis in Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases, 8th Edition, Elsevier, 2014
  3. Salazar JC and Bennett N, Endemic treponematosis including yaws and other spirochetes. Chapter 36, In Manson's Tropical Diseases 23rd edition. Elsevier, 2013
  4. Salazar JC* and Feder HM, Periodic Fever Syndromes. Chapter 176, in Harper’s Textbook of Pediatric Dermatology, 3rd Edition, Edited by A. Irvine, P. Hoeger and A. Yan, 2011, Blackwell Publishing Ltd.
  5. Radolf JD, Salazar JC, and Dattwyler RJ, Lyme Disease in Humans, in Borrelia; Chapter 18 in Molecular Biology, Host Interaction and Pathogenesis.  Edited by: D. Scott Samuels and Justin D. Radolf.  Caister Academic Press, UK, March 2010.
  6. Salazar JC*. Management of an HIV-positive pregnant woman with a positive VDRL test from an area endemic for Treponema infection. Cohen & Powderly/Infectious Diseases 3e/Practice Point 23, Elsevier, March 2010
  7. Berrien VM, Salazar JC*, Reynolds E and McKay K. Section 4, Special Populations: Adherence to Antiretroviral Therapy in HIV-Infected Pediatric Patients Improves with Home- Based Intensive Nursing Intervention. In: Medication Adherence in HIV/AIDS, Jeffrey Laurence, Editor (2004).
  8. Salazar JC*. Antibiotic treatment for streptococcal pharyngitis: Part I: Penicillin first? In: Issues in Infectious Diseases, Vol 3, Streptococcal Pharyngitis, Optimal Management. 112-123. S. Karger AG, Basel, Switzerland, 2004
  9. Salazar JC and Radolf JD. Management of an HIV-positive pregnant woman with a positive VDRL test from an area endemic for Treponema infection. Cohen & Powderly/Infectious Diseases 2e/Chapter 66a, 725 – 727, Elsevier, 2003
  10. Lopez P, Levy A, Caicedo Y, Salazar JC, Osorio MA. Consenso para manejo de enfermedades infecciosas en pediatría. Asociación Colombiana de Infectología. Centro Editorial Catorse SCS, Cali, Colombia, 1997

Peer Reviewed Publications Authorship as Part of a Study Group

  1. Mitchell CD1, Chernoff MC, Seage GR 3rd, Purswani MU, Spiegel HM, Zilleruelo G, Abitbol C, Heckman B, Ponce CB, Oleske JM; Salazar, JC in the IMPAACT 219/219C Study Team. Pediatr Nephrol. 2015 Jan;30(1):153-65. doi: 10.1007/s00467-014-2909-1. Epub 2014 Aug 24
  2. Abzug MJ, Song LY, Levin MJ, Nachman SA, Borkowsky W, Pelton SI; Salazar JC in the International Maternal Pediatric Adolescent AIDS Clinical Trials Group P1024 and P1061s Protocol Teams. Antibody persistence and immunologic memory after sequential pneumococcal conjugate and polysaccharide vaccination in HIV-infected children on highly active antiretroviral therapy. Vaccine. 2013 Oct 1;31(42):4782-90.
  3. Patel K, Van Dyke RB, Mittleman MA, Colan SD, Oleske JM, Seage GR 3rd; International Maternal Pediatric Adolescent AIDS Clinical Trials 219. Salazar JC in the 219C Study Team. The impact of HAART on cardiomyopathy among children and adolescents perinatally infected with HIV-1.  J Infect Dis. 2012 Aug 15;206(4):512-22.
  4. Abzug MJ, Qin M, Levin MJ, Fenton T, Beeler JA, Bellini WJ, Audet S, Sowers SB, Borkowsky W, Nachman SA, Pelton SI, Rosenblatt HM; International Maternal Pediatric Adolescent AIDS Clinical Trials Group.  Salazar JC in the P1024 and P1061s Protocol Teams  Immunogenicity, immunologic memory, and safety following measles revaccination in HIV-infected children receiving highly active antiretroviral therapy. J Infect Dis. 2012 Aug 15;206(4):512-22
  5. Nachman SA, Chernoff M, Gona P, Van Dyke RB, Dankner WM, Seage GR 3rd, Oleske J, Williams PL; Salazar JC in PACTG 219C Team. Incidence of noninfectious conditions in perinatally HIV-infected children and adolescents in the HAART era. Arch Pediatr Adolesc Med. 2009 Feb;163(2):164-71. Erratum in: Arch Pediatr Adolesc Med. 2009 Apr;163(4):364.
  6. Patel K, Ming X, Williams PL, Robertson KR, Oleske JM, Seage GR 3rd;     Salazar JC in International Maternal Pediatric Adolescent AIDS Clinical Trials 219/219C Study Team. Impact of HAART and CNS-penetrating antiretroviral regimens on HIV encephalopathy among perinatally infected children and adolescents. AIDS. 2009 Sep 10;23(14):1893-901.
  7. Patel K, Hernan MA, Williams PL, Seeger JD, McIntosh K, Van Dyke RB, Seage GR. Van Dyke RB, Wang L, Williams PL; Salazar JC in the Pediatric AIDS Clinical Trials Group 219C Team. Toxicities associated with dual nucleoside reverse-transcriptase inhibitor regimens in HIV-infected children.  J Infect Dis. 2008 Dec 1;198(11):1599-608
  8. Salazar JC in the Pediatric AIDS Clinical Trials Group 219/219C study team. Long term effectiveness of highly active antiretroviral therapy on the survival of children and adolescents with HIV infection:  A 10 year follow-up study.  CID 2008:46, 507-515.
  9. Lindsey JC, Malee KM, Brouwers P, Hughes MD; Salazar J in the PACTG 219C Study Team. Neurodevelopmental Functioning in HIV-Infected Infants and Young Children Before and After the Introduction of Protease Inhibitor–Based Highly Active Antiretroviral Therapy. Pediatrics 119 (3) pp. e681-e693, 2007
  10. Fiscus SA, Kovacs A, Petch LA, Hu C, Wiznia AA, Mofenson LM, Yogev R, McIntosh K, Pelton SI, Napravnik S, Stanley K, Nachman SA.; Salazar JC in the PACTG 338 group. Baseline resistance to nucleoside reverse transcriptase inhibitors fails to predict virologic response to combination therapy in children (PACTG 338).  AIDS Res Ther. 6;4:2, 2007
  11. Arguedas A, Emparanza P, Schwartz RH, Soley C, Guevara S, de Caprariis PJ, and Espinosa G. Salazar JC, in protocol A0661091 team. A randomized, multicenter, double blind, double dummy trial of single dose azithromycin versus high dose amoxicillin for treatment of uncomplicated acute otitis media.  PIDJ, 24(2), 153-161, 2005
  12. Abzug MJ, Pelton SI, Song L, Fenton T, et al.; Salazar JC, in PACTG 1024 protocol team. Immunogenicity, safety, and predictors of response after a pneumococcal conjugate and pneumococcal polysaccharide vaccine series in HIV infected children receiving HAART. PIDJ, 25(10), 920-929, 2006
  13. Farley J, Gona P, Crain M, Cervia J, Oleske J, Seage G, Lindsey: Salazar J, in PACTG 219 Team. Prevalence of elevated cholesterol and associated risk factors among perinatally HIV- infected children (4-19 years old) in Pediatric AIDS Clinical Trials Group 219C. J Acquir Immune Defic Syndr. 1; 38(4):480-7. Apr 2005
  14. DM. Gaughan, MD Hughes, JM Oleske, KM Carol, A Gore, Sharon Nachman: JC Salazar in the Pediatric AIDS Clinical Trials Group 219C Team. Psychiatric Hospitalizations Among Children and Youths With Human Immunodeficiency Virus Infection. Pediatrics 113 (6) pp. e544-e551, 2004.
  15. Chang-Heok S, Oleske JM, Brady MT, Spector SA, Borkowsky W, Burchett SK, Foca MD, Handelsman E, Jimenez E, Dankner MD: Salazar J, in PACTG 219 Team. Long Term effects of protease inhibitor based combination therapy on CD4 T-cell recovery in HIV-1-infected children and adolescents.  The Lancet, 362, 2045-2051, 2003.
  16. Kaplan SL, Deville JG, Yogev R, Morfin MR, Wu E, Adler S, Edge-Padbury B, Naberhuis- Stehouwer S, Bruss JB, and Salazar JC in The Linezolid Pediatric Study Group. Linezolid versus vancomycin for treatment of resistant Gram-positive infections in children. Pediatr Infect Dis J 22(8): 677-686; 2003
  17. Krause PJ, McKay K, Gadbaw J, Christianson D, Closter L, Lepore T, Telford III SR, Sikand V, Ryan R, Persing D, Radolf JD, Spielman A: Salazar JC, in Tick-Borne Infection Study Group. Increasing Health Burden of Human Babesiosis in Endemic Sites. Am J Trop Med Hyg, 68(4), 431-436, 2003.
  18. Dorenbaum, A, Cunningham CK, Gelber RD, Culnane M, Mofenson L, Britto P, ekacewicz C, Delfraissy JF, Cunningham-Schrader B, Mirochnick M and Sullivan JL for the international PACTG 316 team. Salazar JC, in: PACTG 316 Study Team. Two-Dose Intrapartum/Newborn Nevirapine to Standard Antiretroviral Therapy to Reduce Perinatal Human Immunodeficiency Virus type-1 Transmission: JAMA, 288(2), 2002
  19. Caughan DM, Hughes MD, Seage GR, Selwyn PA, Carey VJ, Gortmaker SL, and Oleske JM. Salazar J in PACTG 219 Team. The prevalence of pain in pediatric HIV/AIDS as reported by participants in the pediatric late outcomes study (PACTG 219).  Pediatrics, 109(6), 2002.14
  20. Cunningham CK, Chaix ML, Rekacewicz C, Britoo P, Rouzioux RD, Gelber RD, Dorembaum A, Delfraissy JF, Bazin B, Mofenson L, and Sullivan JL. Salazar JC in: the Pediatric AIDS Clinical Trials Group 316 Study Team. Two-dose intrapartum/newborn nevirapine and standard antiretroviral therapy to reduce perinatal HIV transmission: a randomized trial. JID, 186:181-8. 2002.
  21. Krause PJ, McKay K, Thompson CA, Sikand VJ, Lentz R, Lepore T, Closter L, Christianson D, Telford SR, Persing D, Radolf J, Spielman A. Salazar JC, in: the Deer Associated Infection Study Group. Disease-specific diagnosis of coinfecting tickborne zoonoses: babesiosis, human granulocytic ehrlichiosis, and Lyme disease. CID; 34:1184-1191, 2002.
  22. Krogstad P, Lee S, Johnson G, Stanley K, McNamara J, Moye J, Jackson JB, Aguayo R, Diedume A, Khoury M, Mendez H, Nachman S, Wiznia A.Salazar JC in the Pediatric AIDS Clinical Trials Group 377 Study Team. Nucleoside analogue reverse transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir for pretreated children infected with HIV type 1. CID 34, 991-1001, 2002.

Scientific Presentations In Chronological Order

  1. Salazar JC, Gerber MA, and Goff CW: Long Term Outcome of Children Treated for Early Lyme Disease. Oral presentation at the Society for Pediatric Research, Baltimore, Maryland. May 1992.
  2. Salazar JC, Hohenboken MJ, Londoño LJ, Liebeler CL, Meier J, and Giebink GS. Pneumococcal Vaccine Implications From Seroepidemiologic Study of Colombian Children. Poster # 239 presented at the Infectious Disease Society of America meeting Orlando, Florida, 1994.
  3. Salazar, JC, Londoño, LJ, Liebeler CL, Trujillo FA, Giebink GS. Conjugate pneumococcal vaccine strategies from seroepidemiologic study of Colombian children. Oral presentation 0-39.393.  VII Panamerican Infectious Disease Congress, Cartagena, Colombia, May 28-31, 1995.
  4. Salazar JC, Daly KA, Muggli M, Liebeler C, Lindgren B, and Giebink GS.    Type 14 anti pneumococcal antibodies predict early onset otitis media. Oral presentation at the International Conference on Otitis Media Pathogenesis. Fort Lauderdale, Florida, June 1995.
  5. Castañeda CR, Velez JD, Salazar JC.  Epidemia de S. pyogenes en un hospital de tercer nivel. Presented at the Congreso Colombiano de Medicina Interna, Bogotá, Colombia.  October 1996.
  6. Hoyos F, Salazar JC, Velez JD. Factores de riesgo en infección nosocomial en operaciones cardiovasculares. Presented at the Congreso Colombiano de Medicina Interna, Octubre 1996. Santa Fe de Bogotá.
  7. Lozano F, Caicedo Y, Jaramillo AC, Mattar S, Salazar JC, Velez LA, Villanueva G, Jimenez G, Merino N, Villegas MV, Mejia GI, Jones RN, Pfaller MA. Multi-Center evaluation of antimicrobial resistance to six broad-spectrum B-lactams in Colombia using the Etest method. Presented at the 1997 ICAAC, Toronto, Canada.
  8. Crespo MP, Castaneda CR, Velez JD, Salazar JC.   Listeriosis in a tertiary care center in Colombia.  Presented at the 1998 ICAAC, San Diego, California.    
  9. Crespo MP, Castañeda MP, Velez JD, Salazar JC.   Epidemiología del S. pneumoniae en la Fundación Valle del Lili, Cali, Colombia. Presented at the IV Colombian Infectious Diseases Association Meeting, Cartagena, Colombia, June, 1999.
  10. Reynolds  E,  Berrien  V,  Acosta-Glynn  C,  and  Salazar  JC.    Home based, intense, nursing intervention trial improves adherence to HAART in HIV infected children (poster # 275). Presented at the 2001 Pediatric Academic Societies Meeting, Baltimore Maryland, April 2001
  11. Salazar JC, Sellati TJ, Kiely T, Feder HM, Krause PJ, Dardick KR, Buckman RL, Warren CW, KJ Pellegrino JL, Moynihan NT and Radolf JD. Erythema Migrans Immunologic Window to Lyme Disease (poster 601). Presented at the 39th, Infectious Diseases Society of America, San Francisco, California, October 25-28, 2001.
  12. Acosta-Glynn CI, Fernandez NL, Neil R, and Salazar JC. Hartford (Connecticut/USA) youth HIV linkage to care (HYHIL). ThPeG8356 Poster presentation at the XIII International AIDS Conference, Barcelona, Spain. July 11, 2002
  13. Weeks B, Toro-Salazar OH, and Salazar JC.    Kawasaki disease at Connecticut Children’s Medical Center. Presented at the 40th IDSA meeting in Chicago, Illinois (October 24 –27th), 2002.
  14. Ellis JM, Rivera L, Reyes G, Castillo F, Castillo P, Tejada M and Salazar JC. Cefepime in Neonatal Meningitis. Poster presentation at the 2004 PAS and ESPR Annual Meetings. San Francisco, CA, May 1-5
  15. Natt  BC  and  Salazar  JC.   Variations in Pediatric Tuberculosis Screening in Connecticut Schools. Presented oral symposia at the Easter Society for Pediatric Research Meeting, Greenwich Connecticut, March, 2005 and for poster presentation at the 2005 Academic Pediatric Societies Annual Meeting, Washington D.C. May 14-17th
  16. Salazar JC, Cruz A, Trujillo R, Pope C, Obando AM, Sombredero A, Saravia N and Radolf JD. Immunity in early syphilis: pathway to HIV co-infection. Poster presentation at the July, 2005, ISSTDR meeting, Amsterdam, The Netherlands.
  17. Rathi A, Cooley J, Salazar J, Radolf J, Spooner K, Michael N, and Jagodzinski L: Real-Time PCR Detection of Treponema pallidum: A Time Course Correlation with Antibody Response. Presented at the CHI Nucleic Acid Based Technologies: Applications Amplified Meeting. June 27-28th, 2005 Baltimore, Maryland.
  18. Lucini SE, Ellis JM and Salazar JC. Adverse Effects of Protease Inhibitors in Pediatric and Adolescent Patients. Poster presentation at American Society for Health System Pharmacists Midyear Clinical Meeting, Las Vegas Dec 4-8, 2005.
  19. Sabo JP, Cahn P, Della Negra M, Castelli-Gattinara G, Fortuny C, Yogev R, Salazar J, Chan- Loi Yong CL, Mikl J, and Jelaska A. Population Pharmacokinetic (PK) Assessment of Systemic Steady-State Tipranavir (TPV) Concentrations for HIV+ Pediatric Patients Administered Tipranavir/Ritonavir (TPV/r) 290/115 mg/m2 and 375/150 mg/m2 BID (BI 1182.14 and PACTG 1051 Study Team). Poster presentation (# 687) at the 2006, CROI meeting, Denver, Colorado, February 2006.
  20. Salazar J., Cahn P., Della Negra M., Castelli-Gattinara G., Fortuny C., Flynn P., Giaquinto C., Yogev R., Capparelli E., Fenton T., Mikl J., Jelaska A., PACTG 1051. Efficacy and safety results of 48 weeks of treatment with APTIVUS oral solution co-administered with low dose ritonavir (APTIVUS/r) in children and teenagers (Phase I/IIa study). Oral presentation at the International AIDS Meeting, Toronto, Canada, August, 2006.
  21. St. Germain RM, Lucini SE, Ellis JM., Coleman CI., and Salazar JC. Dyslipidemia differences among protease inhibitors (PIs) in children. Poster presentation (#187). American College of Clinical Pharmacy, 2006 Annual Meeting, Oct 26-29, 2006, St. Louis, MO
  22. Salazar JC, Cahn P, Della Negra M, Castelli-Gattinara G, Fortuny G, Flynn P, Yogev R, Ruan PK, Mikl J, Jelaska A. Predictors of response to TPV/r in pediatric patients: results of PACTG1051/BI1182.14 (Poster R-130). Poster presentation at the 2007, Conference on Retroviruses (CROI), February, 2007 Los Angeles, CA.
  23. Salazar JC, Aristizabal G, Pulido C, Duque J.    Congenital syphilis epidemiology in Cali, Colombia (Poster 684). Accepted for poster presentation at the 2007 ISSTDR in Seattle, WA. July, 2007.
  24. Salazar JC. The immunologic consequences of stealth pathogenicity. Presented at the Yearly University of Connecticut Health Center, Immunology Program Retreat. Avery Point, New London, Connecticut, October 12th, 2007.
  25. Lapidus S, Chitkara P, Feder F, Salazar JC, Aksentijevich I, Barham B, A Balu, Barron K, Kastner D, Stojanov S. Unraveling the Pathogenesis of Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) Syndrome: An Immunological Approach. Presented at The Fifth International Congress on Familial Mediterranean Fever and Systemic Auto- inflammatory Diseases Rome, April 4 -8, 2008.
  26. O’Boyle J, Wells L, Salazar JC.     Enhanced Awareness, Education and Prevention of HIV Infection and STDs in North Central Connecticut Public Schools.Presented at the Trinity College Health Fellows Research Meeting, April 29, 2008, Hartford, CT.
  27. Salazar JC, Cahn P, Giaquinto C, Yogev R, Mikl J, Jelaska A, for the PACTG1051 study team. Efficacy and safety profile of APTIVUS oral solution or capsules co-administered with low dose ritonavir (APTIVUS/r) in treatment experienced children and teenagers after two years of treatment  (Phase  I/IIa  study). Accepted for Poster presentation at the 2008, Mexico City, International AIDS Society Meeting.
  28. Salazar JC, Lavake C, Cruz AR, Krueger W, Olson C, Moore M, Anguita J and Radolf JD. Borrelia burgdorferi elicits phagocytosis dependent, non TLR1/2 or TLR5 mediated, inflammatory signals in human monocytes. Accepted for poster presentation at the 10th Biennial Meeting of the International Endotoxin and Innate Immunity Society, Edinburgh University, Scotland, United Kingdom, July, 2008.
  29. Sivia  Lapidus,  et  al.  Salazar  JC.     Immune Dysregulation in Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) Syndrome Involving the Gamma Interferon-inducible Protein 10 (IP-10), a Cytokine Chemotactic for T Lymphocytes. Presented at the 2008 ACR/ARHP Annual Scientific Meeting in San Francisco, CA
  30. Cruz AR, Ramirez L, Zuluaga AV, Navas A, Valderrama L, Radolf JD and Salazar JC. Secondary Syphilis Circulating Innate Immune Cell Dysfunction. Poster Presentation at the ICAAC/IDSA Meeting.  Washington, D.C. October, 2008   
  31. Cruz AR, Aristizabal GE, Salazar JC, Public Health Strategies to Control Congenital Syphilis in Cali, Colombia.  Presented at the July 2009 ISSTDR/BASHH Meeting, London, England (poster # 1582672)
  32. Salazar JC, Cervantes JL, La-Vake C, Dunham ES, Petzke MM, and Radolf JR. Phagosomal signaling by Bb induces diverse pro- and anti-inflammatory responses in human monocytes through a cooperative interaction between TLR1/2 and TLR8. Accepted for poster presentation at the Gordon Conference for Spirochetal Research, Ventura Beach, CA, January 2010.
  33. Cruz AR, Pillay A, La-Vake C, Valencia C, Ramirez L, Radolf JD, and Salazar JC. Systemic innate immune responses during untreated secondary syphilis. Accepted for oral presentation at the Gordon Conference for Spirochetal Research, Ventura Beach, CA, January 2010.
  34. J. Deville, J. Goldfarb, S. Kaplan, O. Equils, D. Huang*, J. Ang and JC Salazar. Linezolid use in the treatment of vancomycin-resistant Enterococcus in paediatric patients (Abstr. 1251) (Los Angeles, Cleveland, Houston, New York, Detroit, Hartford, US). Accepted for poster presentation at the 20th European Congress of Clinical Microbiology and Infectious Diseases. Vienna from 10 – 13 April 2010.
  35. Cruz AR, Ramirez LG, Radolf JD and Salazar JC.   Secondary Syphilis – Deciphering the Paradox.  Poster presentation at the 2011, ISSTDR Meeting, July 2011, Quebec, Canada.
  36. Cervantes JL, LaVake C and Salazar JC.   Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes. Oral presentation at the 9th Joint Meeting of ICS-ISICR CYTOKINES AND INTERFERONS: FROM THE BENCH TO THE BEDSIDE, International Cytokine Society Meeting, Florence, Italy, October 2011.
  37. Cruz AR, Ramirez LG, Radolf JD, Salazar JC. Emergence of a CD56negCD16bright Natural Killer Cell subset in blood of secondary syphilis patients. Oral poster presentation at the January 27th Gordon conference for Spirochetal Biology, Ventura, CA.
  38. Cervantes JL, La Vake CJ, Salazar JC. Human TLR8 is activated upon recognition of Borrelia burgdorferi RNA in the phagosome of human monocytes, Poster presentation at the January 27th 2012, Gordon conference for Spirochetal Biology, Ventura, CA.
  39. Cruz AR, Ramirez L, Pillay A, Radolf JR, Salazar JC, Strain analysis T. pallidum, Cali, Colombia,  2013, IUSTI/ISSTDR meeting in Vienna, Austria
  40. Castrillon MA, Cruz AR, Salazar JC, Congenital syphilis in Buenaventura, Colombia, 2013 IUSTI/ISSTDR meeting, Vienna, Austria.
  41. Jorge Cervantes, Yuxiao Chang, Junhong Luo, Ping Wang, Guolian Li, Carson La Vake, Kelly Hawley, Yijun Ruan, Justin Radolf, and Juan C. Salazar. Distinguising the role of MyD88 in phagosomal signaling upon recognition of Borrelia burgdorferi by murine macrophages through Transcriptome Analysis. Presented at the 2014 Gordon Research Conference for Spirochetal Biology, Ventura, CA, Janaury 2014.
  42. Kelly L. Hawley, Jorge L. Cervantes, Carson J. La Vake, Justin D. Radolf, Juan C. Salazar Phagosomal signaling of human macrophage in response to Borrelia burgdorferi is enhanced with IFNγ, presented at the 2014, Gordon Research Conference for Spirochetal Biology, Ventura, CA, January 2014. 
  43. Jorge Cervantes, M.D., Ph.D., Yuxiao Chang, Ph.D., Junhong Luo, Ph.D., Ping Wang, Ph.D., Guolian Li, Ph.D, Carson La Vake, M.Sc., Kelly Hawley, Ph.D., Yijun Ruan, Ph.D., Justin Radolf, M.D. and Juan C. Salazar, M.D., M.P.H. Transcriptome analysis of the phagosomal signaling upon recognition of Borrelia burgdorferi , the Lyme   disease spirochete, in macrophages. Poster presentation at the 2014 PAS/ASPR Annual Meeting, Vancouver, Canada, May 2014.

 


Juan C. Salazar

Professor and Chair

 

  • : (860) 545-8566
  • DEPARTMENTDepartment of Pediatrics And Immunology
    University of Connecticut School Of Medicine
  • COUNTRY USA