Publications
Refereed Publications(* Denotes Student Contribution)
Refereed Articles
- Jeffery, D., Naoko, K., You, Z., Gharib, M., Wyse, B., , Erin Drury, Michael Weireich, Pierre Thibault, Alain Verreault, HisaoMasai, Krassimir Yankulov (2015). CDC28 regulates the association of Chromatin Assembly Factor I with chromatin. C ell Cycle, 14 (01), 74 - 85.
- Jeffery, D., Yankulov, K., Crerar, A., & Ritchie, K. (2014). How to achieve accurate peer assessment for high value written assignments in a senior undergraduate course. Assessment and Evaluation in Higher Education.
- Yankulov, K. (2013). Dynamics and stability: epigenetic conversions in position effect variegation. Biochemistry and Cell Biology, 91, 6-13.
- Jeffery*, D., Wyse*, B., Muhammad*, R., Brown*, G., You, Z., Oshidari* R, Masai H, Yankulov KY (2013). Analysis of epigenetic stability and conversions in Saccharomyces cerevisiae reveals a novel role of CAF-I in position-effect variegation Nucleic Acids Research, 41 (18), 8475-88.
- Wyse*, B., Oshidary*, R., Jeffery*, D., & Yankulov, K. (2013). Parasite epigenetics and immune evasion: lessons from budding yeast. Epigenetics & Chromatin, 19 (1), 1.
- Yankulov, K. &Couto, R. (2012). Peer review in class: metrics and variations in a senior course Biochem. Biochemistry and Molecular Biology Education, 40, 161-168.
- Chisamore-Robert*, P., Peeters*, S., Shostak*, K., & Yankulov, K. (2012). Directional telomeric silencing and lack of canonical B1 elements in two silencer Autonomously Replicating Sequences in S. cerevisiae. BMC Molecular Biology, 113, 34.
- Yankulov, K. (2011). Dare to challenge the silence? Telomeric gene silencing revisited. The Nucleus, 2, 513-516.
- Power, P., Jeffery, D., Rehman, M. A., Chatterji, A., & Yankulov, K. (2011). Sub-telomeric core X and Y' elements in S. cerevisiae suppress extreme variations in gene silencing. PLoS ONE.
- Yankulov, K. (2010). A Zn-finger in Dbf4 is pointing to genotoxic hypersensitivity. Cell Cycle, 9 (10), 1875-6.
- Espinosa, M. C., Rehman, M. A., Chisamore-Robert, P., Jeffery, D., & Yankulov, K. (2010). GCN5 is a positive regulator of origins of DNA replication in Saccharomyces cerevisiae. PLoS ONE.
- Mathews, A., Holland, L., & Yankulov, K. (2009). The interaction between EAP30 and ELL is modulated by MCM2. F EBS Letters, 583, 3431-6.
- Rehman, M. A. & Yankulov, K. (2009). The dual role of autonomously replicating sequences as origins of replication and as silencers. Current Genetics, 55, 357-63.
- Rehman, M. A., Wang, D., Fourel, G., Gilson, E., & Yankulov, K. (2009). Subtelomeric ACS-containing proto-silencers act as antisilencers in replication factors mutants in Saccharomyces cerevisiae. Molecular Biology of the Cell, 20, 631-41.
- Berthiau, A. S., Yankulov, K., Bah, A., Revardel, E., Luciano, P., Wellinger RJ, Geli V, Gilson E. (2006). Subtelomeric proteins negatively regulate telomere elongation in budding yeast. EMBO Journal, 25, 846-56.
- Rehman, M. A., Fourel, G., Mathews, A., Ramdin, D., Espinosa, M., Gilson E, Yankulov K. (2006). Differential requirement of DNA replication factors for subtelomeric ARS consensus sequence protosilencers in Saccharomyces cerevisiae .G enetics, 174, 1801-10.
- Pinhero, R., Liaw, P., & Yankulov, K. (2004). A uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1.Biological Procedures Online, 6, 163-72.
- Pinhero, R., Liaw, P., Bertens, K., & Yankulov, K. (2004). Three cyclin-dependent kinases preferentially phosphorylate different parts of the C-terminal domain of the large subunit of RNA polymerase II. The FEBS Journal, 271, 1004-14.
- Holland, L. & Yankulov, K. (2003). Two forms of RNA polymerase II holoenzyme display different abundance during the cell cycle. Biochemical and Biophysical Research Communications, 302, 484-8.
- Dziak, R., Leishman, D., Radovic, M., Tye, B. K., & Yankulov, K. (2003). Evidence for a role of MCM (mini-chromosome maintenance)5 in transcriptional repression of sub-telomeric and Ty-proximal genes in Saccharomyces cerevisiae .J ournal of Biological Chemistry, 278, 27372-81.
- Kramer, D. J., Gauthier, L., & Yankulov, K. (2002). Higher-accuracy method for measuring minichromosome stability in S. cerevisiae. BioTechniques, 32, 1036-40.
- Holland, L., Gauthier, L., Bell-Rogers, P., & Yankulov, K. (2002). Distinct parts of minichromosome maintenance protein 2 associate with histone H3/H4 and RNA polymerase II holoenzyme. The FEBS Journal, 269, 5192-202.
- Gauthier, L., Dziak, R., Kramer, D. J., Leishman, D., Song, X., Ho J, Radovic M, Bentley D, Yankulov K. (2002). The role of the carboxyterminal domain of RNA polymerase II in regulating origins of DNA replication in Saccharomyces cerevisiae .G enetics, 162, 1117-29.
- Yankulov, K., Todorov, I., Romanowski, P., Licatalosi, D., Cilli, K., McCracken S, Laskey R, Bentley DL.= (1999). MCM proteins are associated with RNA polymerase II holoenzyme. Molecular and Cellular Biology, 19, 6154-63.
- Yankulov, K. & Bentley, D. (1998). Transcriptional control: Tat cofactors and transcriptional elongation. Current Biology, 8 (13), 447-9.
- McCracken, S., Fong, N., Yankulov, K., Ballantyne, S., Pan, G., Greenblatt J, Patterson SD, Wickens M, Bentley DL. (1997). The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. Nature, 385, 357-61.
- Yankulov, K. & Bentley, D. L. (1997). Regulation of CDK7 substrate specificity by MAT1 and TFIIH.EMBO Journal, 16, 1638-46.
- McCracken, S., Fong, N., Rosonina, E., Yankulov, K., Brothers, G., Siderovski D, Hessel A, Foster S, Shuman S, Bentley DL. (1997). 5'-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II. G enes& Development, 11, 3306-18.
- Yankulov, K., Pandes, M., McCracken, S., Bouchard, D., & Bentley, D. L. (1996). TFIIH functions in regulating transcriptional elongation by RNA polymerase II in Xenopus oocytes. Molecular and Cellular Biology, 16, 3291-9.
- Yankulov, K., Yamashita, K., Roy, R., Egly, J. M., & Bentley, D. L. (1995). The transcriptional elongation inhibitor 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole inhibits transcription factor IIH-associated protein kinase. Journal of Biological Chemistry, 270, 23922-5.
- Yankulov, K., Blau, J., Purton, T., Roberts, S., & Bentley, D. L. (1994). Transcriptional elongation by RNA polymerase II is stimulated by transactivators. CELL, 77, 749-59.
- Hadjiolova, K. V., Martinova, Y. S., Yankulov, K., Davidov, V., Kancheva, L. S., Hadjiolov AA. (1989). An immunocytochemical study of the proliferating cell nuclear matrix antigen p125/6.5 during rat spermatogenesis. Journal of Cell Science, 93, 173-7.
- Yankulov, K., Hadjiolova, K. V., Kournev, K. V., Getov, C., &Hadjiolov, A. A. (1989). The use of a monoclonal antibody against a proliferating cell nuclear matrix antigen in the study of solid human tumors. International Journal of Cancer, 43, 800-4.
Presentations of Refereed Papers
International
- Yankulov, K. (2012). Regulation of positional variegation at the telomeres: links to DNA replication. Epigenetics and Genomic Stability Conference (CSBCB), Whistler, Canada-British Columbia.
- Chisamore-Robert, P., Jeffery, D., & Yankulov, K. (2011). Telomeric gene silencing by Autonomously Replicating Sequences (ARS) in S. cerevisiae: role of B1 elements.Keystone symposium on DNA Replication, Unknown, Unknown.
- Paulsen, T., Jeffery, D., Rehman, M., You, Z., Masai, H., Krassimir Yankulov (2010). Is Cdc7p/Dbf4p the major kinase for Chromatin Assembly Factor (CAF-I). 12th Symposium on DNA Replication and Repair, Buffalo, New York.
- Robert-Chisamore, P. & Yankulov, K. (2010). Functional differences between silencer and replicator ARS of Saccharomyces cerevisiae through analysis of the B1 element.12th Symposium on DNA Replication and Repair, Buffalo, New York.
- Mathews, A. & Yankulov, K. (2009). Interaction between EAP30, ELL and MCM2.FEBS Conference, Prague, Czech Republic.
- Yankulov, K. (2009). Positional variegation at yeast telomeres.University of Hokkaido, Sapporo, Japan.
- Yankulov, K. (2009). Positional variegation at yeast telomeres.Tokyo Metropolitan Institute of Medicine, Tokyo, Japan.
- Rehman, M. A., Espinosa, M., & Yankulov, K. (2008). GCN5 functions as a positive regulator of origins in S. cerevisiae. 11th Symposium on DNA Replication and Repair, Buffalo, New York.
- Mathews, A. & Yankulov, K. (2007). Novel Interacting partners of MCM2.10th Symposium on DNA Replication and Repair, Buffalo, New York.
- Rehman, M. A., Kita, E., Wang, D., & Yankulov, K. (2007). Telomeric ACSand the regulation of silencing in S.cerevisiae. 10th Symposium on DNA Replication and Repair, Buffalo, New York.
- Yankulov, K. (2007). ACS and DNA replication trans-factors as regulators of gene silencing in S.cerevisiae. 10th Symposium on DNA Replication and Repair, Buffalo, New York.
- Rehman, M. A. & Yankulov, K. (2006). Differential requirements for replication factors for subtelomeric ACS proto-silencers in S.cerevisiae. 10th Symposium on DNA replication and repair, Buffalo, New York.
- Rehman, M. A. & Yankulov, K. (2006). Differential requirements for replication factors for subtelomeric ACS proto-silencers in S.cerevisiae. Differential requirements for replication factors for subtelomeric ACS proto-silencers in S.cerevisiae, Buffalo, New York.
- Rehman, M. A., Wang, D., & Yankulov, K. (2005). Effects of MCM5 in the repression pattern of sub-telomeric genes in S.cerevisiae. 48th Annual Conference of the Genetics Society of Canada (GSC), Banff, Canada-Alberta.
- Wang, D., Rehman, M. A., & Yankulov, K. (2005). The role of MCM proteins and other DNA replication factors in the regulation of repression at telomeres in S. cerevisiae. 9th Symposium on DNA Replication and Repair, Buffalo, New York.
- Wang, D., Rehman, M. A., & Yankulov, K. (2005). The role of MCM proteins and other DNA replication factors in the regulation of repression at telomeres in S. cerevisiae. 9th Symposium on DNA Replication and Repair, Buffalo, New York.
- Yankulov, K., Rehman, M., & Wang, D. (2005). Analysis of the mechanism of repression of subtelomeric genes in mcm5 mutants in S. cerevisiae. Telomerase and Telomere Function Conference, Ladenburg, Germany.
- Yankulov, K. (2004). Regulation of gene expression at the telomeres of S.cerevisiae.EcoleNormale Superiure, Lyon, France.
- Yankulov, K., Dziak, R., Leishman, D., Radovic, M., Bertens, K., Rhalena Thomas (2003). A role of MCM5 in Chromatin Remodeling at Origins of Replication and in Repression of Sub-telomeric and Ty-proximal genes in S. cerevisiae .Chromatin Structure and Function Meeting, Philadelphia, Pennsylvania.
- Yankulov, K. (2003). Regulation of DNA replication and of sub-telomeric gene expression in S. cerevisiae. National Institutes of Health, Bethesda, Maryland.
- Holland, L., Downey, M., & Yankulov, K. (2002). Distinct Parts of MCM2 Associate with HistoneH3/H4 and RNA polymerase II Holoenzyme.EMBL Meeting on Transcription, Heidelberg, Germany.
- Yankulov, K., Gauthier, L., Dziak, R., &Radovic, M. (2002). A role of the carboxyterminal domain of RNA polymerase II in regulating origins of DNA replication in S. cerevisiae. ELSO meeting, Nice, France.
- Gauthier, L., Kramer, D., Song, X., Radovic, M., Ho, J., David Bentley, Robert Scalfani, Krassimir Yankulov (2001).G enetic Interaction between MCM5 and the carboxyterminal domain of RNApol II in S. cerevisiae. Eukaryotic DNA Replication, Cold Spring Harbor, New York.
- Holland, L., Song, X., Downey, M., Gauthier, L., & Yankulov, K. (2001). The interaction of RNApol II holoenzyme with MCM proteins is mediated b y the N-terminus of MCM2. Mechanisms of Eukaryotic Transcription, Cold Spring Harbor, New York.
National
- Chisamore-Robert, P. & Yankulov, K. (2011). Gene silencing by Autonomously Replicating Sequences (ARS) in S. cerevisiae: role of B1 elements. First Canadian Epigenetics Conference. Epigenetic Eh!, London, Canada-Ontario.
- Yankulov, K. &Rehman, M. A. (2008). Sub-telomeric ACS-containing proto-silencers act as anti-silencers in replication factors mutants in S.cerevisiae. Yeast Genetics and Molecular Biology Meeting, Toronto, Canada-Ontario.
- Yankulov, K. (2006). At origins and ends - MCM proteins, SAGA and the regulation of DNA replication and of sub-telomeric gene expression in S. cerevisiae. University of Waterloo, Waterloo, Canada-Ontario.
- Rehman, M. A., Wang, D., & Yankulov, K. (2005). Effects of MCM5 in the repression pattern of sub-telomeric genes in S.cerevisiae. 48th Annual Conference of the Genetics Society of Canada (GSC), Banff, Canada-Alberta.
- Pinhero, R., Liaw, P., Bertens, K., & Yankulov, K. (2003). Phosphorylation pattern of RNA polymerase II carboxyl terminal domain by three cyclin-dependent kinases. HUPO 2nd Annual and IUBMB Congress, Montreal, Canada-Quebec.
- Yankulov, K. (2003). MCM proteins – potential role in the regulation of gene expression.University of Toronto, Toronto, Canada Ontario.
Invited Chapters
- Chisamore-Robert, P., Jeffery, D., & Yankulov, K. (2011). The silencing face of DNA replication: gene repression mediated by DNA replication factors. DNA Replication - Current Advances.InTech Publishing.
- Pinhero, R. & Yankulov, K. (2013). Expression and purification of recombinant Cyclin Dependent Kinases: CDK7, CDK8 and CDK9.In M. Orzáez and E. Payá (Eds.), Cyclin-Dependent Kinases. This invited chapter has been accepted by the editors in 2013. Publication is pending
Non-Refereed Articles
- Yankulov, K. (2014). More than Spelling and Grammar: Students Who Prefer to Write Outperform Students Who Prefer to Present. American Journal of Educational Research.2 (11).
- Yankulov, K., Kounev, K. V., &Getov, C. (1989). Monoclonal antibody against a proliferating cell nuclear matrix antigen as a fast marker of tumor boundary in solid tumors of the larynx. O tolaryngologiaPolska, 3, 15-18.
Presentations of Non-Refereed Papers
International
- Oshidary, R., Wyse, B., Rowlands, H., & Yankulov, K. (2014). Epigenetic inheritance in S.cerevisiae: interaction between PCNA, CAF-I and RRM3. The 2nd Canadian Conference on Epigenetics: Epigenetics, Eh!, London, Canada-Ontario.
National
- Yankulov, K. (2013). Telomere position effect: the ins and outs of epigenetic maintenance. External Seminar Series, Dept. of Biology, York University, Toronto, Canada-Ontario.
- Yankulov, K. (2013). Telomere position effect in P. falciparum and S.cerevisiae: a terminal connection? Toronto Hospital Network, Toronto, Canada-Ontario.
Posters And/Or Papers Presented At Conferences
- Jeffery, D. & Yankulov, K. (2014). The role of CAF-I in epigenetic conversions and its control by kinases.The 2nd Canadian Conference on Epigenetics: Epigenetics, Eh!, London, Canada-Ontario.
- Jeffery, D., You, Z., Masai, H., Verreault, A., & Yankulov, K. (2013). The role of Cac1p in epigenetic conversions of sub-telomeres in S.cerevisiae. Cold Spring Harbor Laboratory Symposium on Chromatin and Epigenetics, Cold Spring Harbor, United States of America.
- Jeffery, D., Yankulov, K., Crerar, A., & Ritchie, K. (2013). How to achieve accurate peer evaluation for high value written assignments in a senior undergraduate course. Symposium on Scholarship of Teaching and Learning, Banff, Canada-Alberta.
- Jeffery, D., You, Z., Masai, H., & Yankulov, K. (2012). Telomere position effect and the passing/pausing of replication forks.Epigenetics and Genomic Stability, Whistler, Canada-British Columbia.
- Jeffery, D. & Yankulov, K. (2012). Peer review in a senior course. 25th Annual Teaching and Learning Innovations Conference, Guelph, Canada-Ontario.