SciForschen Online Publications

Publications

Peer reviewed publications in print or other media
Research Investigations

Coutts IG, Hamblin MR. Synthesis of N,N-diaryltoluene-4-sulphonamides. J Chem Soc Perkin I; 1975;2445-6.
Coutts IG, Hamblin MR. An unusual reaction of methylmagnesium iodide with cyclohexadienones. J Chem Soc Chem Commun 1976;58-9.
Coutts IG, Hamblin MR, Tinley EJ. The enzymatic oxidation of phenolic tetrahydroisoquinoline-1-carboxylic acids. J Chem Soc Perkin I; 1979;2744-50.
Grundon MF, Hamblin MR, Harrison DM. Biosynthesis of aromatic isoprenoids Part 5: The preparation of 1-(3,3-dimethylallyl)-L-tryptophan and cyclo-L-alanyl tryptophan and their non-incorporation into echinulin. J Chem Soc Perkin I; 1980;1294-8.
Buchanan JG, Hamblin MR, Sood GR, Wightman RH. The biosynthesis of pyrazofurin and formycin. J Chem Soc Chem Commun 1980;917-8.
Coutts IG, Hamblin MR. Synthesis of spiroheterocycles by oxidative coupling of phenolic sulphonamides. J Chem Soc Chem Commun 1980;949-50.
Coutts IG, Hamblin MR. Spirodienones Part 2: The synthesis of some heterocyclic spirodienones by phenolic coupling. J Chem Soc Perkin I 1981;493-7.
Buchanan JG, Hamblin MR, Kumar A, Wightman RH. The biosynthesis of showdomycin – Studies with stable isotopes and the determination of principal precursors. J Chem Soc Chem Commun 1984;1515-7.
Hamblin MR, Potter BV. E. coli Ada regulatory protein repairs the SP diastereoisomer of alkylated DNA. FEBS Lett 1985;189(2):315-7.
Hamblin MR, Cummins JH, Potter BV. Mung bean nuclease. A mechanistic investigation of the DNA cleavage with inversion of configuration at phosphorous. Biochem Soc Trans 1986;14:899-900.
Hamblin MR, Potter BV, Gigg R. Bisphosphorylation of a vic-diol using a phosphite chemistry approach. Synthesis of myo-inositol 4,5-bisphosphate. J Chem Soc Chem Commun 1987;626-27.
Hamblin MR, Flora JS, Potter BV. Myo-Inositol phosphorothioates, phosphatase-resistant analogues of myo-inositol phosphates. Synthesis of DL-myo-inositol 1,4-bisphosphate and DL-myo-inositol 1,4-bisphosphorothioate. Biochem J 1987;246(3):771-4. PMC1148343
Hamblin MR, Potter BV, Gigg R. Synthesis of myo-inositol phosphates and analogues using a phosphite chemistry approach. Biochem Soc Trans 1987;15:415-6.
Hamblin MR, Cummins JH, Potter BV. Mung bean (Phaseolus aureus) nuclease. A mechanistic investigation of the DNA-cleavage reaction using a dinucleoside phosphorothioate. Biochem J 1987;241(3):827-33. PMC1147636
Hamblin MR, Newman EL. Photosensitizer targeting in photodynamic therapy. I. Conjugates of haematoporphyrin with albumin and transferrin. J Photochem Photobiol B 1994;26(1):45-56.
Hamblin MR, Newman EL. Photosensitizer targeting in photodynamic therapy. II. Conjugates of haematoporphyrin with serum lipoproteins. J Photochem Photobiol B 1994;26(2):147-57.
Molpus KL, Kato D, Hamblin MR, Lilge L, Bamberg M, Hasan T. Intraperitoneal photodynamic therapy of human epithelial ovarian carcinomatosis in a xenograft murine model. Cancer Res 1996;56(5):1075-82.
Hamblin MR, Miller JL, Hasan T. The effect of charge on the interaction of site-specific photoimmunoconjugates with human ovarian cancer cells. Cancer Res 1996; 56(22):5205-10.
Duska LR, Hamblin MR, Bamberg MP, Hasan T. Biodistribution of charged F(ab’)2 photoimmunoconjugates in a xenograft model of ovarian cancer. Br J Cancer1997;75(6):837-44. PMC2063388. (the first two authors made equal contributions)
Soukos NS, Hamblin MR, Hasan T. The effect of charge on cellular uptake and phototoxicity of polylysine chlorine6 conjugates. Photochem Photobiol 1997;65(4):723-9. (the first two authors made equal contributions)
Momma T, Hamblin MR, Hasan T. Hormonal modulation of the accumulation of 5-aminolevulanic acid-induced protoporphyrin and phototoxicity in prostate cancer cells. Int J Cancer 1997;72(6):1062-9.
Soukos NS, Ximenez-Fyvie LA, Hamblin MR, Socransky SS, Hasan T. Targeted antibacterial photochemotherapy. Antimicrob Agents Chemother 1998;42(10):2595-601. PMC105903
Hamblin MR, Bamberg MP, Miller JL, Hasan T. Cationic photoimmunoconjugates between monoclonal antibodies and hematoporphyrin: selective photodestruction of ovarian cancer cells. Appl Opt 1998;37:7184-92.
Momma,T, Hamblin MR, Wu HC, Hasan T. Photodynamic therapy of orthotopic prostate cancer with benzoporphyrin derivative: local control and distant metastasis. Cancer Res 1998;58(23):5425-31.
Hamblin MR, Rajadhyaksha M, Momma T, Soukos NS, Hasan T. In vivo fluorescence imaging of the transport of charged chlorine6 conjugates in a rat orthotopic prostate tumor. Br J Cancer 1999;81(2):261-8. PMC2362866
Duska LR, Hamblin MR, Miller JL, Hasan T. Combination photoimmunotherapy and cisplatin: effects on human ovarian cancer ex vivo. J Natl Cancer Inst 1999;91(18):1557-63.
Khadem J, Veloso Jr. AA, Tolentino F, Hasan T, Hamblin MR. Photodynamic tissue adhesion with chlorin(e6) protein+ conjugates. Invest Ophthalmol Vis Sci 1999;40(13):3132-7.
Del Governatore M, Hamblin MR, Piccinini EE, Ugolini G, Hasan T. Targeted photodestruction of human colon cancer cells using charged 17.1a chlorine6 immunoconjugates. Br J Cancer 2000;82(1):56-64.
Molpus KL, Hamblin MR, Rizvi I, Hasan T. Intraperitoneal photoimmunotherapy of ovarian carcinoma xenografts in nude mice using charged photoimmunoconjugates. Gynecol Oncol 2000;76(3):397-404.
Del Governatore M, Hamblin MR, Shea CR, Rizvi I, Molpus KG, Tanabe K, Hasan T. Experimental photoimmunotherapy of hepatic metastases of colorectal cancer with a 17.1A chlorine6 immunoconjugate. Cancer Res 2000;60(15):4200-5.
Kodama T, Hamblin MR, Doukas, AG. Cytoplasmic molecular delivery with shock waves: importance of impulse. Biophysical J 2000;79(4):1821-32. PMC1301074
Hamblin MR, Miller, JL, Ortel B. Scavenger-receptor targeted photodynamic therapy. Photochem Photobiol 2000;72(4):533-40.
Hamblin MR, Del Governatore M, Rizvi I, Hasan T. Biodistribution of charged 17.1a photoimmunoconjugates in a murine model of hepatic metastasis of colorectal cancer. Br J Cancer 2000;83(11):1544-51. PMC2363424
Soukos NS, Hamblin MR, Keel S, Fabian RL, Deutsch TF, Hasan T. Epidermal growth factor receptor targeted immunophotodiagnosis and photoimmunotherapy of oral precancer in vivo. Cancer Res 2001;61(11):4490-6.
Hamblin MR, Miller JL, Rizvi I, Ortel B, Maytin EV, Hasan T. Pegylation of a chlorine6 polymerconjugate increases tumor targeting of photosensitizer. Cancer Res 2001;61(19):7155-62.
Hamblin MR, O’Donnell DA, Murthy N, Contag CH, Hasan T. Rapid control of wound infections by targeted photodynamic therapy monitored by in vivo bioluminescence imaging. Photochem Photobiol 2002;75(1):51-7.
Kodama T, Doukas, AG, Hamblin MR. Shock wave-mediated molecular delivery into cells. Biochem Biophys Acta 2002;1542(1-3):186-94.
Hamblin MR, O’Donnell DA, Murthy N, Rajagopalan K, Michaud N, Sherwood ME, Hasan T. Polycationic photosensitizer conjugates: photodynamic inactivation of bacteria depends on conjugate structure and Gram classification. J Antimicrob Chemother 2002;49(6):941-51.
Hamblin MR, Miller JL, Rizvi I, Ortel B. Degree of substitution of chlorin(e6) conjugated to charged poly-L-lysine chains affects their cellular uptake, localization and phototoxicity towards macrophages and cancer cells. J X-ray Sci Technol 2002;10:139-52.
Kodama T, Doukas, AG, Hamblin MR. Delivery of ribosome-inactivating protein toxin into cancer cells with shock waves. Cancer Lett 2003;189(1):69-75.
Hamblin MR, Zahra T, Contag CH, McManus AT, Hasan T. Optical monitoring and treatment of potentially lethal wound infections in vivo.J Infect Dis 2003;187(11):1717-25.
Hamblin MR, Miller JL, Rizvi I, Loew HG, Hasan T. Pegylation of charged polymer-photosensitizer conjugates: effects on photodynamic efficacy. Br J Cancer 2003; 89(5): 937-43. PMC2394480
Gad F, Zahra T, Francis KP, Hasan T, Hamblin MR. Targeted photodynamic therapy of established soft-tissue infections in mice.Photochem Photobiol Sci 2004; 3: 451-8. PMC3071693
Hamblin MR, Hasan T. Photodynamic therapy: a new antimicrobial approach to infectious disease? Photochem Photobiol Sci 2004; 3(5): 436-50. PMC3071049
Gad F, Zahra T, Hasan T, Hamblin MR. Photodynamic inactivation of Gram-positive pathogenic bacteria: effect of growth phase and extracellular slime. Antimicrob Agents Chemother, 2004; 48(6):2173-8. PMC415578
Shi L, Takahashi K, Dundee J, Shahroor-Karni S, Thiel S, Jensenius JC, Gad F, Hamblin MR, Sastry KN, Ezekovitz RA. Mannose-binding lectin deficit mice are susceptible to infection with staphylococcus aureus. J Exp Med 2004; 199(10):1379-90. PMC2211809
Khadem JJ, Martino M, Anatelli F, Dana MR, Hamblin MR. Healing of perforating rat corneal incisions closed with photodynamic laser-activated tissue glue. Lasers Surg Med 2004; 35(4):304-11. PMC3071689
Ganz, RA. Viveiros J, Ahmad A, Ahmadi A, Khalil A Tolkoff MJ, Nishioka NS, Hamblin MR. Helicobacter pylori in patients can be killed by visible light. Lasers Surg Med 2005; 36(4): 260-5. PMC3071042
Demidova TN, Hamblin MR. Effect of cell-photosensitizer binding and cell density on microbial photoinactivation. Antimicrob Agents Chemother; 2005;49(6):2329-35. PMC1140487
Hamblin MR, Viveiros J, Yang C, Ahmadi A, Ganz, RA, Tolkoff MJ. Helicobacter pylori accumulates photoactive porphyrins and is killed by visible light. Antimicrob Agents Chemother, 2005: 49(7): 2822–2827. PMC1168670
Demidova TN, Gad F, Zahra T, Francis KP, Hamblin MR. Monitoring photodynamic therapy of localized infections by bioluminescence imaging of genetically engineered bacteria. J Photochem Photobiol B. 2005; 81:15-25. PMC3071690
Lambrechts SA, Demidova TN, Aalders MC, Hasan T, Hamblin MR. Photodynamic therapy for Staphylococcus aureus infected burn wounds in mice. Photochem Photobiol Sci. 2005; 4: 503 – 509. PMC3071043
Liu Q, Hamblin MR. Macrophage-targeted photodynamic therapy: scavenger receptor expression and activation state. Int J Immunopathol Pharmacol. 2005, 18: 391-402. PMC3071040
Demidova TN, Hamblin MR . Photodynamic inactivation of Bacillus spores mediated by phenothiazinium dyes. Appl Environ Microbiol, 2005, 71: 6918–6925. PMC1287731
Tegos GP, Demidova TN, Arcila-Lopez D, Lee H, Gali H, Wharton T, Hamblin MR . Cationic fullerenes are effective and selective antimicrobial photosensitizers. Chem Biol, 2005, 12: 1127-1135. PMC3071678
Tegos GP, Hamblin MR . Phenothiazinium antimicrobial photosensitizers are substrates of bacterial multidrug resistance pumps, Antimicrob Agents Chemother, 2006, 50: 196-203. PMC1346798
Møller-Kristensen M, Shi L, Ip E,. Gowda LD, Hamblin MR, Thiel S, Jensenius JC, Ezekowitz RA, Takahashi K. Deficiency of mannose-binding lectin greatly increases susceptibility to post-burn infection with Pseudomonas aeruginosa. J Immunol, 2006, 176(3):1769-1775. PMC3071691
Tawakol A, Castano AP, Anatelli F, Bashian G, Stern J, Zahra T, Gad F, Chirico S, Ahmadi A, Fischman AJ, Muller JE, Hamblin MR. Photosensitizer delivery to vulnerable atherosclerotic plaque: comparison of macrophage-targeted conjugate versus free chlorin(e6). J Biomed Optics, 2006, 11: 210-218. PMC2936819
Castano AP, Liu Q, and Hamblin MR. A green fluorescent protein-expressing murine tumour but not its wild-type counterpart is cured by photodynamic therapy. Brit J Cancer, 2006, 94, 391-397. PMC2361144
Tegos GP, Anbe M, Yang C, Demidova TN, Satti M, Mroz P, Janjua S, Gad F and Hamblin MR.Protease stable polycationic photosensitizer conjugates between polyethyleneimine and chlorin(e6) for broad spectrum antimicrobial photoinactivation. Antimicrob Agents Chemother, 2006, 50: 1402-1410. PMC1426948
Burkatovskaya M, Tegos GP, Swietlik E, Demidova TN, P Castano A, Hamblin MR. Use of chitosan bandage to prevent fatal infections developing from highly contaminated wounds in mice. Biomaterials. 2006 Aug; 27(22):4157-4164. PMC2935802
Borbas KE, Mroz P, Hamblin MR, and Lindsey JS. Bioconjugatable porphyrins bearing a compact swallowtail motif for water solubility. Bioconj Chem, 2006, 17: 638-653. PMC3072562
Anatelli F, Mroz P, Liu Q, Yang C, Castano AP, Swietlik E, Hamblin MR. Macrophage-targeted photosensitizer conjugate delivered by intratumoral injection. Mol Pharmaceut. 2006, 6: 654-664. PMC2504868
Foley JW, Song X, Demidova TN, Jilal F, Hamblin MR. Synthesis and properties of benzo[a]phenoxazinium chalcogen analogs as novel broad-spectrum antimicrobial photosensitizers. J Med Chem. 2006, 49: 5291-5299. PMC3071243
Garcez, AS; Ribeiro MS, Tegos GP, Nunez SC, Jorge AO, Hamblin MR. Antimicrobial photodynamic therapy combined with conventional endodontic treatment to combat root canal infection. Lasers Surg Med. 2007 Jan;39(1): 59-66. PMC3071045
Møller-Kristensen M, Hamblin MR, Thiel S, Jensenius JC, Takahashi K. Burn injury reveals altered phenotype in mannan-binding lectin deficient mice. J Invest Dermatol, 2007, 127: 1524-1531. PMC2936508
Tang ·HM, Hamblin MR, ·Yow, CM. A comparative in vitro photoinactivation study of clinical isolates of multidrug-resistant pathogens,. J Infect Chemother, 2007, 13(2): 87-91. PMC2933783
Castano AP, Dai T, Yaroslavsky I, Cohen R, Apruzzese AW, Smotrich MH, Hamblin MR. Low-level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time. Lasers Surg Med. 2007, 39(6):543-550. PMC2935792
Mroz P, Pawlak A, Satti M, Lee H, Wharton T, Gali H, Sarna T and Hamblin MR. Functionalized fullerenes mediate photodynamic killing of cancer cells: Type I versus Type II photochemical mechanism. Free Radical Biol Med, 2007 Sep 1;43(5):711-9. PMC1995806
Fuchs, BB, Tegos GP, Hamblin MR, Mylonakis E. Susceptibility of Cryptococcus neoformans to photodynamic inactivation is associated with cell wall integrity. Antimicrob Agents Chemother, 2007, 51(8):2929-36. PMC1932496
Demidova-Rice TN, Salomatina EV, Yaroslavsky AN, Herman IM, Hamblin MR, Low-level light stimulates excisional wound healing in mice, Lasers Surg Med, 2007, 39(9):706-715. PMC2935798
Garcez AS, Nunez SC, Lage-Marques JL, Hamblin MR, Ribeiro MS. Photonic real-time monitoring of bacterial reduction in root canals by genetically engineered bacteria after chemomechanical endodontic therapy. Braz Dent J. 2007;18(3):202-7. PMC2940265
Apidianakis Y, Mindrinos MN, Xiao W, Tegos GP, Papisov MI, Hamblin MR, Davis RW, Tompkins RG, and Rahme LG. Involvement of skeletal muscle gene regulatory network in susceptibility to wound infection following trauma. PLoS ONE, 2007, 2:e1356-1365. PMC2131783
Tawakol, A., Castano, A. P., Gad, F., Zahra, T., Bashian, G., Migrino, R. Q., Ahmadi, A., Stern, J., Anatelli, F., Chirico, S., Shirazi , A., Syed, S., Fischman, A. J., Muller, J. E., and Hamblin, MR. Intravascular detection of inflamed atherosclerotic plaques with a scavenger receptor-targeted fluorescent photosensitizer. Photochem Photobiol Sci, 2008, 7, 33 – 39. PMC2813573
Garcez, AS, Nunez SC, Hamblin MR, and Ribeiro MS. Antimicrobial effects of photodynamic therapy on patients with necrotic pulps and periapical lesion. J Endodont, 2008, 34:138-142. PMC2808698
Dai T, Tegos GP, Rolz-Cruz G, Cumbie WE, Hamblin MR. Ultraviolet-C inactivation of dermatophytes: Implications for treatment of onychomycosis, Br J Dermatol,2008, 158:1239-1246. PMC2808700
Castano AP, Mroz P, Wu MX, Hamblin MR. Photodynamic therapy plus low-dose cyclophosphamide generates antitumor immunity in a mouse model. Proc Natl Acad Sci USA, 2008,105(14):5495-5500. PMC2291083
Burkatovskaya M, Castano AP, Demidova-Rice TN, Tegos GP, Hamblin MR. Effect of chitosan acetate bandage on wound healing in infected and non-infected wounds in mice. Wound Repair Regenerat, 2008, 16(3):425-431. PMC2805166
Tegos GP, Masago K, Aziz F, Higginbotham A, Stermitz FR, Hamblin MR. Inhibitors of bacterial multidrug efflux pumps potentiate antimicrobial photoinactivation. Antimicrob Agents Chemother, 2008. 52(9): 3202-3209. PMC2533468
Wang XL, Wang HW, Hillemanns P, Hamblin MR. Distinctive features of foreskin condylomata acuminata associated with diabetes mellitus. Acta Derm Venereol, 2008, 88(6): 578-583. PMC2808699
Kee HL, Bhaumik J, Diers JR, Mroz P, Hamblin MR, Bocian DF, Lindsey JS, Holten D. Photophysical characterization of imidazolium-substituted Pd(II), In(III), and Zn(II) porphyrins as photosensitizers for photodynamic therapy. J Photochem Photobiol A, 2008, 200: 346–355. PMC2615400
Dai T, Tegos GP, Burkatovskaya M, Castano AP, Hamblin MR. Chitosan acetate bandage as a topical antimicrobial dressing for infected burns. Antimicrob. Agents Chemother. 2009. 53(2):393-400. PMC2630614
Mroz P, Bhaumik J, Dogutan DK, Aly Z, Kamal Z, Khalid J, Kee HK, Bocian DF, Holten D, Lindsey JS and Hamblin MR. Imidazole metalloporphyrins as photosensitizers for photodynamic therapy: Role of molecular charge, central metal and hydroxyl radical production. Cancer Lett, 2009, 282:63-76. PMC2782654
George S, Hamblin MR, Kishen A. Uptake pathways of anionic and cationic photosensitizers into bacteria. Photochem Photobiol Sci, 2009. 8(6), 788-795. PMC2797759
Szokalska A, Makowski M, Nowis D, Wilczynski GM, Kujawa M, Wójcik C, Mlynarczuk-Bialy I, Salwa P, Bil J, Janowska S, Agostinis P, Verfaillie T, Bugajski M, Gietka J, Issat T, Glodkowska E, Mrówka P, Stoklosa T, Hamblin MR , Mróz P, Jakóbisiak M, Golab J. Proteasome inhibition potentiates antitumor effects of photodynamic therapy in mice through induction of ER stress and unfolded protein response. Cancer Res. 2009. 69(10):4235-43. PMC2785802
Lembo AJ, Ganz RA , Sheth S, Cave D, Kelly C, Levin P, Kazlas PT, Baldwin PC III, Lindmark WR, McGrath JR, Hamblin MR. Treatment of Helicobacter pylori Infection with Intra-Gastric Violet Light Phototherapy – a Pilot Clinical Trial. Lasers Surg Med. 2009. 41(5):337-344. PMC2841969
Dai T, Tegos GP, Lu Z, Huang L, Zhiyentayev T, Franklin MJ, Baer DG, Hamblin MR. Photodynamic therapy for Acinetobacter baumannii burn infections in mice. Antimicrob. Agents Chemother. 2009 53: 3929-3934. PMC2737832
Huang Y-Y, Chen A C-H, Carroll JD. Hamblin MR. Biphasic dose response in low-level light therapy. Dose Response Journal, 2009, 7, 358-383. PMC2790317
Huang L , Terakawa M, Zhiyentayev T, Huang Y-Y, Sawayama, Y, Jahnke A, Tegos, GP, Wharton T, Hamblin MR. Innovative cationic fullerenes as broad-spectrum light-activated antimicrobials. Nanomedicine: Nanotechnology, Biology, and Medicine, 2010, 6(3), 442 – 452. PMC2879475
Schiffer F, Johnston AL. Polcari A, Teicher MH, Webb RH, Hamblin MR. Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: A pilot study of 10 patients with major depression and anxiety, Behavioral Brain Res. 2009, 5, 46-55. PMC2796659
Dai T, Tegos GP, Zhiyentayev T, Mylonakis E, Hamblin MR. Photodynamic Therapy for Methicillin-Resistant Staphylococcus aureus Infection in a Mouse Skin Abrasion Model. Lasers Surg Med;2010, 42: 38–44. PMC2820267
Coleman JJ, Okoli I, Tegos GP, Holson E, Wagner FF, Hamblin MR, Mylonakis E. Characterization of plant-derived saponin natural products against Candida albicans. ACS Chem Biol, 2010, 5(3):321-332. PMC2965462
Ragas X, Dai T, Tegos GP, Agut M, Nonell S, Hamblin MR. Photodynamic inactivation of Acinetobacter baumannii using phenothiazinium dyes: in-vitro and in-vivo studies. Lasers Surg Med;2010, 42:384–390. Reviewed in http://epinews.com/Newswire/2010/07/23/could-light-activated-dyes-defeat-antibiotic-resistant-acinetobacter/. PMC2935797
Park J, Mroz P, Salomatina E, Hamblin MR, Yaroslavsky AN. Dye-enhanced multimodal confocal microscopy for noninvasive detection of skin cancers in mouse models. J Biomed Optics, 2010, 15(2), 026023. PMC2866259
Mroz P, Huang YY, Szokalska A, Zhiyentayev T, Janjua S, Nifli AP,. Sherwood ME, Ruzié C, Borbas KE, Fan D, Krayer M, Balasubramanian T, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. Innovative stable synthetic bacteriochlorins overcome the resistance of melanoma to photodynamic therapy. FASEB J, 2010, 24, 3160–3170. PMC2923353
Kishen A, Upadya M, Tegos GP Hamblin MR. Efflux pump inhibitor potentiates photodynamic inactivation of Enterococcus faecalis biofilm. Photochem Photobiol. 2010 Nov-Dec;86(6):1343-9. PMC2991588
Chen Z, Zhou S, Chen J, Deng Y, Luo Z, Chen H, Hamblin MR, Huang M. Pentalysine b-Carbonylphthalocyanine Zinc: An Effective Tumor-Targeting Photosensitizer for Photodynamic Therapy. ChemMedChem, 2010, 5(6):890-8. PMC2935799
Huang YY, Mroz P, Zhiyentayev T, Sharma SK, Balasubramanian T, Ruzié C, Borbas KE, Fan D, Krayer M, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. In Vitro Photodynamic Therapy and Quantitative Structure-Activity Relationship Studies with Stable Synthetic Near-Infrared-Absorbing Bacteriochlorin Photosensitizers. J Med Chem, 2010, 53(10):4018-27. PMC2933425
Hamblin MR, Dai T. Can surgical site infections be treated by photodynamic therapy? Photodiagnosis PhotodynTher, 2010, 7(2): 134-136. PMC2945525
Huang L, Huang YY, Mroz P, Tegos GP, Zhiyentayev T, Sharma SK, Lu Z, Balasubramanian T, Krayer M, Ruzié C, Yang E, Kee HL, Kirmaier C, Diers JR, Bocian DF, Holten D, Lindsey JS, Hamblin MR. Stable Synthetic Cationic Bacteriochlorins As Selective Antimicrobial Photosensitizers. Antimicrob Agents Chemother, 2010, 54; 3834–3841. PMC2934952
Huang L; Dai T; Hamblin MR. Antimicrobial photodynamic inactivation and photodynamic therapy for infections. Methods Mol Biol. 2010, 635: 155-73. PMC2933785
Garcez AS, Nunez SC, Hamblin MR, Suzuki H, Ribeiro MS. Photodynamic therapy associated with conventional endodontic treatment in patients with antibiotic resistant microflora. A Preliminary report. J Endodont, 2010; 36(9): 1463-1466. doi:10.1016/j.joen.2010.06.001
Chiang LY, Padmawar PA, Rogers-Haley JE, So G, Canteenwala T, Thota S, Tan LS, Pritzker K, Huang YY, Sharma SK, Kurup DB, Hamblin, MR. Wilson BC, Urbas A. Synthesis and characterization of highly photoresponsive fullerenyl dyads with a close chromophore antenna–C60 contact and effective photodynamic potential. J Mater. Chem., 2010, 20, 5280 - 5293, PMC2947801
Hamblin, MR. Introduction to Experimental and Clinical Studies Using Low-Level Laser (Light) Therapy (LLLT). Lasers Surg Med, 2010; 42:447–449. PMC2939452
Lu Z, Dai T, Huang L, Kurup DB, Tegos GP, Jahnke A, Wharton T, Hamblin, MR. Photodynamic therapy with a cationic functionalized fullerene rescues mice from fatal wound infections. Nanomedicine UK. 2010; 5(10):1525-33. PMC3047412
Dai T, Tegos GP, St. Denis TG, Anderson D, Sinofsky E, Hamblin, MR. Ultraviolet-C Irradiation for Prevention of Central Venous Catheter Related Infections: An In-vitro Study. Photochem Photobiol. 2011 Jan-Feb;87(1):250-5. doi: 10.1111/j.1751-1097.2010.00819.x. PMC3010268
Ragàs X, Sánchez-García D, Ruiz-González R, Dai T, Agut M, Hamblin MR, Nonell S. Cationic Porphycenes as Potential Photosensitizers for Antimicrobial Photodynamic Therapy. J Med Chem. 2010, 53(21):7796-7803. PMC2981434
Mroz P, Szokalska A, Wu MX, Hamblin MR. Photodynamic Therapy of Tumors Can Lead to Development of Systemic Antigen-Specific Immune Response. PLoS ONE, 2010, 5 (12), e15194-05. PMC3001867
Garcez SG, Núñez SC, Baptista MS, Daghastanli NA, Itri R, Hamblin MR, Ribeiro MS. Antimicrobial mechanisms behind photodynamic effect in the presence of hydrogen peroxide. Photochem Photobiol Sci, 2010 Apr;10(4):483-90. PMC3069140
Chen AC, Huang YY, Sharma SK, Hamblin MR. Effects of 810-nm Laser on Murine Bone-Marrow-Derived Dendritic Cells. Photomed Laser Surg. 2011 29 (6), 383–389. PMC3105346
Naeser MA, Saltmarche A, Krengel MH, Hamblin MR, Knight JA. Improved Cognitive Function After Transcranial, Light-Emitting Diode Treatments in Chronic, Traumatic Brain Injury: Two Case Reports. Photomed Laser Surg. 2011. May;29(5):351-8. Reviewed in http://topnews.us/content/237119-transcranial-light-therapy-may-help-tbi-patients. PMC3104287
Dai T, Kharkwal GB, Zhao J, St Denis TG, Wu Q, Xia Y, Huang L, Sharma SK, d’Enfert C, Hamblin MR. Ultraviolet-C Light for Treatment of Candida albicans Burn Infection in Mice. Photochem Photobiol. 2011 Mar-Apr;87(2):342-9. PMC3048910
St Denis TG, Huang L, Dai T, Hamblin MR. Analysis of the Bacterial Heat Shock Response to Photodynamic Therapy-Mediated Oxidative Stress. Photochem Photobiol. 2011 May-Jun;87(3):707-13. PMC3082629
Huang L, Zhiyentayev T, Xuan Y, Azhibek D, Kharkwal GB, Hamblin MR. Photodynamic inactivation of bacteria using polyethylenimine–chlorin(e6) conjugates: Effect of polymer molecular weight, substitution ratio of chlorin(e6) and pH. Laser Surg Med, 2011 43:313–323. PMC3449165
Fiamegos YC, Kastritis PL, Exarchou V, Han H, Bonvin MJ, Vervoot J, Lewis K, Hamblin MR, Tegos GP. Antimicrobial and efflux pump inhibitory activity of caffeoylquinic acids from Artemisia absinthium against Gram-positive pathogenic bacteria. PLoS ONE, 2011, 6(4): e18127. PMC3070693
Wainwright M, Dai T, Hamblin MR. Antimicrobial photodynamic therapy in the colon: delivering a light punch to the guts? Photochem Photobiol, 2011, Jul-Aug;87(4):754-6. PMC3132272
Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto N, Hamblin MR, Morimoto Y. Photodynamic therapy using intra-articular Photofrin for murine MRSA arthritis: biphasic light dose response for neutrophil-mediated antibacterial effect. Laser Surg Med, 2011, 43:221–229. PMC3071702
Mroz P, Xia Y, Asanuma D, Konopko A, Zhiyentayev T, Huang YY, Sharma SK, Dai T, Khan UJ, Wharton T, Hamblin MR, Intraperitoneal photodynamic therapy mediated by a fullerene in a mouse model of abdominal dissemination of colon adenocarcinoma. Nanomedicine, 2011 Dec;7(6):965-74. PMC3183379
Mizuno K, Zhiyentayev T, Huang L, Khalil1 S, Nasim F, Tegos GP, Gali H, Jahnke A, Wharton T, Hamblin MR. Antimicrobial photodynamic therapy with functionalized fullerenes: Quantitative structure-activity relationships. J Nanomedic Nanotechnol 2011, 2:2 http://dx.doi.org/10.4172/2157-7439.1000109. PMC3130518
Prates RA, Kato IT, Ribeiro1 MS, Tegos GP, Hamblin MR. Influence of multidrug efflux systems on methylene blue-mediated photodynamic inactivation of Candida albicans. J Antimicrob Chemother. 2011, Jul;66(7):1525-32. PMC3112030
Huang L, Dai T, Xuan Y, Tegos GP, Hamblin MR. Synergistic combination of chitosan acetate with nanoparticle silver as a topical antimicrobial: efficacy against bacterial burn infections. Antimicrob Agents Chemother. 2011, Jul;55(7):3432-8. Featured in http://www.mdlinx.com/nurse-practitioner/news-article.cfm/3646304. PMC3122390
Mroz P, Yaroslavsky A, Kharkwal GB, Hamblin MR. Cell Death Pathways in Photodynamic Therapy of Cancer. Cancers 2011, 3, 2516-2539.
Chen A C-H, Arany P, Huang YY, Tomkinson EM, Sharma SK Kharkwal GB, Saleem T, Mooney D, Yull FE, Blackwell TS, Hamblin MR. Low-level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts. PLoS ONE, 2011, 6 (7) e22453 PMC3141042
Sharma SK, Kharkwal GB, Sajo M, Huang YY, De Taboada L, McCarthy T, Hamblin MR. Dose response effects of 810-nm laser-light on mouse primary cortical neurons Lasers Surg Med, 2011, 43(8):851-9. PMC3199299
Hamblin MR. Reply to "Championing Photoantimicrobial Discovery". Photodiagn Photodyn Ther. 2011. DOI: 10.1016/j.pdpdt.2011.06.005
Huang YY Sharma SK, Carroll JD, Hamblin MR. Biphasic dose response in low-level light therapy – An update. Dose Response Journal, 2011, 9(4): 602-618. DOI: 10.2203/dose-response.11-009.Hamblin. PMC3315174
Ando T, Xuan W, Xu T, Dai T, Sharma SK, Kharkwal GB, Huang YY, Wu Q., Whalen MJ, Sato S, Obara M, Hamblin MR, Comparison of therapeutic effects between pulsed and continuous wave 810-nm wavelength laser irradiation for traumatic brain injury in mice. PLoS ONE 6 (2011) e26212-26220. PMC3196530
Dai T, Bil de Arce VJ, Tegos GP, Hamblin MR, Blue dye and red light: a dynamic combination for prophylaxis and treatment of cutaneous Candida albicans infections in mice. Antimicrob Agents Chemother, 2011, 55(12): 5710–5717. PMC3232820
Sharma SK Chiang LY, Hamblin MR, Photodynamic therapy with fullerenes in vivo: reality or a dream? Nanomedicine (UK), 2011, Dec;6(10):1813-25. PMC3433279
Tanaka M, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K, Hirayama T, Dai T, Huang L, Hamblin MR, Morimoto Y. Optimal photosensitizers for photodynamic therapy of infections should kill bacteria but spare neutrophils. Photochem Photobiol. 2012 Jan-Feb;88(1):227-32. PMC3253242
Apidianakis Y, Que YA, Xu W, Tegos GP, Zimniak P, Hamblin MR, Tompkins RG, Xiao W, Rahma LG. Down-regulation of glutatione S-transferase alpha 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection. FASEB J, 2012 Feb;26(2):730-7. Epub 2011 Oct 28.
Penjweini R, Loew HG, Hamblin MR, Kratky KW. Long-term monitoring of live cell proliferation in presence of PVP-Hypericin: A new strategy using ms pulses of LED and the fluorescent dye CFSE. J. Microscopy, 2012 Jan;245(1):100-8. PMC3232286
Huang YY, Sharma SK, Dai T, Chung H, Yaroslavsky A, Garcia-Diaz M, Chang J, Chiang LY, Hamblin MR, Can Nanotechnology Potentiate Photodynamic Therapy? Nanotech Rev, 2012, 1(2), 111-146. doi: 10.1515/ntrev-2011-0005
Wu Q, Xuan W, Ando T, Xu T, Huang L, Huang YY, Dai T, Dhital S, Sharma SK. Whalen MJ, Hamblin MR. Low level laser therapy for closed-head traumatic brain injury in mice: effect of different wavelengths. Lasers Surg Med. 2012 Mar;44(3):218-26. doi: 10.1002/lsm.22003 PMID 22275301.
Demidova-Rice TN, Wolf L, Deckenback J, Hamblin MR, Herman IM. Human Platelet-Rich Plasma- and Extracellular Matrix-Derived Peptides Promote Impaired Cutaneous Wound Healing In Vivo. PLoS ONE, 2012, 7 (2), e32146
Li P, Zhou G, Zhu X, Li G, Yan P, Shen L, Xu Q, Hamblin MR. Photodynamic therapy with hyperbranched poly(ether-ester) chlorin(e6) nanoparticles on human tongue carcinoma CAL-27 cells. Photodiagnosis Photodyn Ther. 2012 Mar;9(1):76-82.
Wang M, Huang L, Sharma SK, Jeon S, Thota S, Sperandio FF, Nayka S, Chang J, Hamblin MR, Chiang LY. Synthesis and photodynamic effect of new highly photostable decacationically armed [60]- and [70]fullerene decaiodide monoadducts to target pathogenic bacteria and cancer cells. J Med Chem. 2012 May 10;55(9):4274-85.
Dai T, Fuchs BB, Coleman JJ, Prates RA, Astrakas A, St Denis TG, Ribeiro MS, Mylonakis E, Hamblin MR, Tegos GP Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform. Front. Microbio. 3:120. doi: 10.3389/fmicb.2012.00120.
Tanaka T, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Nemoto K, Shinomiya N, Seki S and Hamblin MR. Photodynamic therapy can induce a protective innate immune response against murine bacterial arthritis via neutrophil accumulation. PLoS ONE, 2012, 2012;7(6):e39823.
Thota S, Wang M, Jeon S, Maragani S, Hamblin MR, Chiang LY. Synthesis and characterization of positively charged pentacationic [60]fullerene monoadducts for antimicrobial photodynamic inactivation. Molecules. 2012 May 7;17(5):5225-43.
Huang L, Xuan Y, Koide Y, Zhiyentayev T, Tanaka M, Hamblin MR. Type I and Type II mechanisms of antimicrobial photodynamic therapy: An in vitro study on Gram-negative and Gram-positive bacteria. Lasers Surg Med, 2012 Aug;44(6):490-9. doi: 10.1002/lsm.22045.
Kawakubo M, Eguchi K, Arai T, Kobayashi K, Hamblin MR, Surface Layer-Preserving Photodynamic Therapy (SPPDT) in a Subcutaneous Mouse Model of Lung Cancer. Lasers Surg Med, 2012 Aug;44(6):500-7. doi: 10.1002/lsm.22046.
Shrestha A, Hamblin MR, Kishen A. Characterization of a conjugate between rose bengal and chitosan for targeted antibiofilm and tissue stabilization effects as a potential treatment of infected dentin. Antimicrob Agents Chemother. 2012 Jul 9. ;56(9):4876-84
García-Díaz M, Kawakubo M, Mroz P, Sagristà ML, Mora M, Nonell S, Hamblin MR. Cellular and vascular effects of the photodynamic agent temocene are modulated by the delivery vehicle. J Control Release, 2012 Sep 10;162(2):355-63 PMID: 22841794
Baxter RM, Dai T, Kimball J, Wang E, Hamblin MR, Wiesmann WP, McCarthy SJ and Baker, SM. Chitosan dressing promotes healing in third degree burns in mice: Gene expression analysis shows biphasic effects for rapid tissue regeneration and decreased fibrotic signaling. J Biomed Mater Res A, 2012. DOI: 10.1002/jbm.a.34328
Hamrahi V, Hamblin MR, Jung W, Benjamin JB, Paul KW, Fischman AJ, Tompkins RG, Carter EA. Gram-negative bacterial infection in thigh abscess can migrate to distant burn depending on burn depth. Interdiscip Perspect Infect Dis. 2012;2012:567140. Epub 2012 Jul 26.
Assis L, Moretti AI, Abrahão TB, de Souza HP, Hamblin MR, Parizotto NA. Low-level laser therapy (808 nm) contributes to muscle regeneration and prevents fibrosis in rat tibialis anterior muscle after cryolesion. Lasers Med Sci. 2012 Aug 17. [Epub ahead of print]
Vecchio D, Dai T, Huang L, Fantetti L, Roncucci G, Hamblin MR. Antimicrobial photodynamic therapy with RLP068 kills methicillin-resistant Staphylococcus aureus and improves wound healing in a mouse model of infected skin abrasion. J Biophotonics. 2012 doi: 10.1002/jbio.201200121.
Dai T, Murray CK, Vrahas MS, Baer DG, Tegos GP, Hamblin MR. Ultraviolet C light for Acinetobacter baumannii wound infections in mice: Potential use for battlefield wound decontamination? J Trauma Acute Care Surg. 2012 Sep;73(3):661-667.
St Denis TG, Dai T, Hamblin MR. Killing bacterial spores with blue light: when innate resistance meets the power of light. Photochem Photobiol. 2012 Sep 5. doi: 10.1111/j.1751-1097.2012.01233.x. PMCID: PMC3556167
Huang L, St Denis TG, Xuan Y, Tanaka M, Huang YY; Zadlo A; Sama T, Hamblin MR. Paradoxical potentiation of methylene blue-mediated antimicrobial photodynamic inactivation by sodium azide: role of ambient oxygen and azide radicals. Free Radical Biol Med, 2012. 53(11): 2062-71, PMCID: PMC3522421
Vatansever F, Hamblin MR. Far infrared radiation (FIR): Its biological effects and medical applications. Photon Laser Med. 2012, 1(4): 255-266.
Vatansever F, Rodrigues NC, Assis LL, Peviani SS, Durigan JL,. Moreira FA, Hamblin MR Parizotto NA. Low intensity laser therapy accelerates muscle regeneration in aged rats. Photon Laser Med. 2012, 1(4):287-297.
Assis L, Moretti AI, Abrahão TB, Cury V, Souza HP, Hamblin MR, Parizotto NA. Low-level laser therapy (808 nm) reduces inflammatory response and oxidative stress in rat tibialis anterior muscle after cryolesion. Lasers Surg Med. 2012 Sep 21. doi: 10.1002/lsm.22077.
Dai T, Garcia B, Murray CK, Vrahas MS, Hamblin MR. UVC light prophylaxis for cutaneous wound infections in mice. Antimicrob Agents Chemother. 2012 Jul;56(7):3841-8. Epub 2012 May 7.
Sperandio, F. F., Sharma, S. K., Wang, M., Jeon, S., Huang, Y.-Y., Dai, T., Nayka, S., de Sousa, S. C.O.M., Chiang, L. Y., and Hamblin, MR. Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C70 and C84O2 fullerene derivatives. Nanomedicine: NBM. 2013; May;9(4):570-9.. pii: S1549-9634(12)00598-9. doi: 10.1016/j.nano.2012.09.005.
Sharma SK, Mroz P, Dai T, Huang YY, St Denis TG, Hamblin, MR. Photodynamic Therapy for Cancer and for Infections: What Is the Difference? Israel J Chemistry, 2012, 52 (8-9), 691-705. DOI: 10.1002/ijch.201100062. PMCID: PMC3522418
Kato IT, Prates RA, Sabino CP, Fuchs BB, Tegos GP, Mylonakis E, Hamblin MR, Ribeiro MS. Antimicrobial photodynamic inactivation inhibits Candida albicans virulence factors and reduces in vivo pathogenicity. Antimicrob Agents Chemother. 2013;8(1):e54387. doi: 10.1371/journal.pone.0054387.
Mandel A. Hamblin MR. A renaissance in low-level laser (light) therapy – LLLT. Photon Laser Med. 2012, DOI 10.1515/plm-2012-0044 [epub ahead of print]
Huang YY, Vecchio D, Avci P, Yin R, Garcia-Diaz M, Hamblin MR. Melanoma resistance to photodynamic therapy: new insights. Biol Chem. 2013 Mar;8(3):331-55. doi: 10.1517/17460441.2013.761202. PMCID: PMC3580014
Aquino AE Jr, Sene-Fiorese M, Paolillo FR, Duarte FO, Oishi JC, Pena AA Jr, Duarte AC, Hamblin MR, Bagnato VS, Parizotto NA. Low-level laser therapy (LLLT) combined with swimming training improved the lipid profile in rats fed with high-fat diet. Lasers Med Sci. 2013 Sep;28(5):1271-80. doi: 10.1007/s10103-012-1223-z PMCID: PMC3594357
Vatansever F, Chandran R, Sadasivam M, Chiang LY, Hamblin MR. Multi-Functionality in Theranostic Nanoparticles: is more Always Better? J Nanomed Nanotechol 2012, 3:8 http://dx.doi.org/10.4172/2157-7439.1000e120
Yang E, Diers JR, Huang YY, Hamblin MR, Lindsey JS, Bocian DF, Holten D. Molecular Electronic Tuning of Photosensitizers to Enhance Photodynamic Therapy: Synthetic Dicyanobacteriochlorins as a Case Study. Photochem Photobiol. 2013 May-Jun;89(3):605-18. doi: 10.1111/php.12021. PMCID: PMC3610834
Huang YY, Nagata K, Tedford CE, McCarthy T, Hamblin MR. Low-level laser therapy reduces oxidative stress in primary cortical neurons in vitro. J Biophotonics, 2012 Dec 27. doi: 10.1002/jbio.201200157.
Xuan W, Vatansever F, Huang L, Wu Q, Xuan Y, Dai T, Ando T, Xu T, Huang YY, Hamblin MR. Transcranial low-level laser therapy improves neurological performance in traumatic brain injury in mice: effect of treatment repetition regimen. PLoS One. 2013;8(1):e53454. doi: 10.1371/journal.pone.0053454.
Gupta A, Dai T, Avci P, Huang YY, Hamblin MR. Ultraviolet Radiation in Wound Care: Sterilization and Stimulation. Adv Wound Care (New Rochelle). 2013 Oct;2(8):422-437. doi:10.1089/wound.2012.0366. PMCID: PMC3797459
Prates RA, Fuchs BB, Mizuno K, Naqvi Q, Kato IT, Ribeiro1 MS, Mylonakis E, Tegos GP, Hamblin MR. Effect of virulence factors on the photodynamic inactivation of Cryptococcus neoformans. PLoS ONE, 2013;8(1):e54387. doi: 10.1371/journal.pone.0054387. PMCID: PMC3548784
Dai T, Gupta A, Huang YY, Yin R, Murray CK, Vrahas MS, Sherwood ME, Tegos GP, Hamblin MR. Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action. Antimicrob Agents Chemother. 2013, 57(3):1238-1245
Avci P, Gupta A, Sadasivam M, Vecchio D, Pam Z, Pam N, Hamblin MR. Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. Semin Cutan Med. 2013, 32(1):41-52
Ferrarasi C, Hamblin MR, Parizotto NA. Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light. Photon Lasers Med. 2012, 1(4), 267-286.
Tanaka M, Mroz P, Dai T, Huang L, Morimoto Y, Kinoshita M, Yoshihara Y, Shinomiya N, Seki S, Nemoto K and Hamblin MR, Linezolid and vancomycin decrease the therapeutic effect of methylene blue-photodynamic therapy in a mouse model of MRSA bacterial arthritis, Photochem Photobiol, 2013 May-Jun;89(3):679-82. doi: 10.1111/php.12040. PMCID: PMC3636181
Wang M, Maragani S, Huang L, Jeon S, Canteenwala T, Hamblin MR, Chiang LY. Synthesis of decacationic [60]fullerene decaiodides giving photoinduced production of superoxide radicals and effective PDT-mediation on antimicrobial photoinactvation. Eur J Med Chem 2013, 63: 170-184.
Kokel D, Cheung CY, Mills R, Coutinho-Budd J, Huang L, Setola V, Sprague J, Jin S, Jin YN, Huang XP, Bruni G, Woolf CJ, Roth BL, Hamblin MR, Zylka MJ, Milan DJ, Peterson RT. Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol. 2013 Apr;9(4):257-63. doi: 10.1038/nchembio.1183. PMCID: PMC3604056
Dai T, Gupta A, Huang YY, Sherwood ME, Murray CK, Vrahas MS, Kielian T, Hamblin MR. Blue Light Eliminates Community-Acquired Methicillin-resistant Staphylococcus aureus in Infected Mouse Skin Abrasions. Photomed Laser Surg. 2013 Nov;31(11):531-8. doi: 10.1089/pho.2012.3365.
Sharma SK, Krayer M, Sperandio FF, Huang L, Huang YY, Holten D, Lindsey JS and Hamblin MR. Synthesis and evaluation of cationic bacteriochlorin amphiphiles with effective in vitro photodynamic activity against cancer cells at low nanomolar concentration. J Porphyrins Phalocyanines, 2013, 17: 73–85. PMCID: PMC3742135
Chibebe Jr J, Fuchs BB, Sabino CP, Junqueira JC, Jorge AOC, Ribeiro MS, Gilmore MS, Rice LB, Tegos GP, Hamblin MR, Mylonakis E. Photodynamic and Antibiotic Therapy Impair thePathogenesis of Enterococcus faecium in a Whole Animal Insect Model. PLoS ONE, 2013, 8 (2) e55926-e55935. PMCID: PMC3573038
Sperandio FF, Huang YY, Hamblin MR. Antimicrobial Photodynamic Therapy To Kill Gram-Negative Bacteria. Recent Pat Antiinfect Drug Discov. 2013 Aug;8(2):108-20
Sperandio FF, Giudice FS, Corrêa L, Pinto DS Jr, Hamblin MR, de Sousa SC. Low-level laser therapy can produce increased aggressiveness of dysplastic and oral cancer cell lines by modulation of Akt/mTOR signaling pathway. J Biophotonics. 2013 Oct;6(10):839-47. doi: 10.1002/jbio.201300015.
Kourtesi C, Ball AR, Huang YY, Jachak SM, Vera DM, Khondkar P, Gibbons S, Hamblin MR, Tegos GP. Microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementation. Open Microbiol J. 2013;7:34-52. doi: 10.2174/1874285801307010034.
Gupta A, Dai T, Hamblin MR. Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice. Lasers Med Sci. 2014 Jan;29(1):257-65. doi: 10.1007/s10103-013-1319-0
St Denis TG, Hamblin MR. Synthesis, bioanalysis and biodistribution of photosensitizer conjugates for photodynamic therapy. Bioanalysis. 2013 May;5(9):1099-1114. doi: 10.4155/bio.13.37. PMCID: PMC3701389
G N, Tan A, Farhatnia Y, Rajadas J, Hamblin MR, Khaw PT, Seifalian AM. Channelrhodopsins: visual regeneration and neural activation by a light switch. N Biotechnol. 2013 Jun 25;30(5):461-74. doi: 10.1016/j.nbt.2013.04.007.
Lakshmanan S, Gupta GK, Avci P, Chandran R, Sadasivam M, Jorge AE, Hamblin MR. Physical Energy for Drug Delivery; Poration, Concentration and Activation. Adv Drug Deliv Rev. 2013 Jun 7. pii: S0169-409X(13)00148-8. doi: 10.1016/j.addr.2013.05.010.
Avci P, Nyame TT, Gupta GK, Sadasivam M, Hamblin MR. Low-Level Laser Therapy for Fat Layer Reduction: A Comprehensive Review. Lasers Surg Med. 2013 Jun 7. 45:349–357. doi: 10.1002/lsm.22153. PMID: 23749426
Huang L, Wang M, Dai T, Sperandio FF, Huang YY, Xuan Y, Chiang LY, Hamblin MR. Antimicrobial photodynamic therapy with decacationic monoadducts and bisadducts of [70]fullerene: in vitro and in vivo studies. Nanomedicine (Lond). 2013 Jun 5.[Epub ahead of print] PMID: 23738632.
Vatansever F, de Melo WC, Avci P, Vecchio D, Sadasivam M, Gupta A, Chandran R, Karimi M, Parizotto NA, Yin R, Tegos GP, Hamblin MR. Antimicrobial strategies centered around reactive oxygen species - bactericidal antibiotics, photodynamic therapy and beyond. FEMS Microbiol Rev. 2013 Nov;37(6):955-89. doi: 10.1111/1574-6976.12026.
Karimi M, Avci P, Mobasseri R, Hamblin MR. Naderi-Manesh H. The novel albumin–chitosan core–shell nanoparticles for gene delivery: preparation, optimization and cell uptake investigation. J Nanoparticle Res. 2013, 15 (5): 1–14. DOI: 10.1007/s11051-013-1651-0 PMCID: PMC3868460
Garcez AS, Núñez SC, Azambuja N Jr, Fregnani ER, Rodriguez HM, Hamblin MR, Suzuki H, Ribeiro MS. Effects of Photodynamic Therapy on Gram-Positive and Gram-Negative Bacterial Biofilms by Bioluminescence Imaging and Scanning Electron Microscopic Analysis. Photomed Laser Surg. 2013 Nov;31(11):519-25. doi: 10.1089/pho.2012.3341
Cury V, Moretti AI, Assis L, Bossini P, de Souza Crusca J, Neto CB, Fangel R, de Souza HP, Hamblin MR, Parizotto NA. Low level laser therapy increases angiogenesis in a model of ischemic skin flap in rats mediated by VEGF, HIF-1α and MMP-2. J Photochem Photobiol B. 2013 Jun 19;125C:164-170. doi: 10.1016/j.jphotobiol.2013.06.004.
Sadasivam M, Avci P, Gupta GK, Lakshmanan S, Chandran R, Huang YY, Kumar R, Hamblin MR. Self-assembled liposomal nanoparticles in photodynamic therapy. Eur J Nanomedicine. 2013 Jul;5(3). DOI: 10.1515/ejnm-2013-0010
de Melo WC, Avci P, de Oliveira MN, Gupta A, Vecchio D, Sadasivam M, Chandran R, Huang YY, Yin R, Perussi LR, Tegos GP, Perussi JR, Dai T, Hamblin MR. Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection. Expert Rev Anti Infect Ther. 2013 Jul;11(7):669-93. doi: 10.1586/14787210.2013.811861.
Avci P, Gupta GK, Clark J, Winkonkal N, Hamblin MR. Low level laser (light) therapy (LLLT) for treatment of hair loss. Lasers Surg Med, 2013 Aug 23. doi: 10.1002/lsm.22170
Jeon S, Haley JE, Flikkema J, Nalla V, Wang M, Sfeir M, Tan LS, Cooper TM, Ji W, Hamblin MR, Chiang LY. Linear and Nonlinear Optical Properties of Photoresponsive [60]Fullerene Hybrid Triads and Tetrads with Dual NIR Two-photon Absorption Characteristics. J Phys Chem C Nanomater Interfaces. 2013 Aug 20;117(33):17186-17195. DOI: 10.1021/jp405424q
Xia Y, Gupta GK, Mroz P, Castano AP, Avci P, Hamblin MR. CpG oligodeoxynucleotide as immune adjuvant enhances photodynamic therapy response in murine metastatic breast cancer. J Biophotonics, 2013; epub online DOI 10.1002/jbio.201300072.
Jeon S, Wang M, Tan LS, Cooper TM, Hamblin MR, Chiang LY. Synthesis of Photoresponsive Dual NIR Two-Photon Absorptive [60]Fullerene Triads and Tetrads. Molecules 2013, 18, 9603-9622; doi:10.3390/molecules18089603
Gilaberte Y, Aspiroz C, Alejandre C, Andres-Ciriano E, Charlez L, Hamblin MR, Rezusta A. Cutaneous sporotrichosis treated with photodynamic therapy: an in vitro and in vivo study. Photomed Laser Surg. 2013 Dec 13. [Epub ahead of print] PMID:24328608
Yin R, Dai, T, Avci P, Jorge A, de Milo W, Vecchio D, Huang YY, Gupta A, Hamblin MR. Light based anti-infectives: ultraviolet C irradiation, photodynamic therapy, blue light, and beyond. Curr Opin Pharmacol, 2013, Oct;13(5):731-62. doi: 10.1016/j.coph.2013.08.009
Tegos GP, Hamblin MR. Disruptive innovations: new anti-infectives in the age of resistance. Curr Opin Pharmacol, 2013 Sep 5. doi:pii: S1471-4892(13)00158-6. 10.1016/j.coph.2013.08.012
Reginato E, Mroz P, Chung H, Kawakubo M, Wolf P, Hamblin MR. Photodynamic therapy plus regulatory T-cell depletion produces immunity against a mouse tumor that expresses a self-antigen. Br J Cancer, 2013 Oct 15;109(8):2167-74. doi: 10.1038/bjc.2013.580
Ando T, Sato S, Kobayashi H, Nawashiro H, Ashida H, Hamblin MR, Obara. M Low-level laser therapy for spinal cord injury in rats: effects of polarization. J Biomed Optics, 2013, 18(9), 98002. DOI: 10.1117/1.JBO.18.9.098002
Mroz P, Vatansever F, Muchowicz A, Hamblin MR. Photodynamic therapy of murine mastocytoma induces specific immune responses against the cancer/testis antigen P1A. Cancer Res. 2013, Nov 1;73(21):6462-70. doi: 10.1158/0008-5472.CAN-11-2572
Chibebe Jr J, Sabino CP, Tan X, Junqueira JC, Wang Y, Fuchs BB, Jorge AO, Tegos GP, Hamblin MR. Mylonakis E. Selective photoinactivation of Candida albicans in the non-vertebrate host infection model Galleria mellonella. BMC Microbiol, 2013, 13:217 http://www.biomedcentral.com/1471-2180/13/217
Huang YY, Nagata K, Tedford CE, Hamblin MR. Low-level laser therapy (810 nm) protects primary cortical neurons against excitotoxicity in vitro. J Biophotonics. 2013 Oct 15. doi: 10.1002/jbio.201300125.
Shrestha A, Hamblin MR, Kishen A. Photoactivated rose bengal functionalized chitosan nanoparticles produce antibacterial/biofilm activity and stabilize dentin-collagen. Nanomedicine. 2013 Nov 4. doi:pii: S1549-9634(13)00586-8. 10.1016/j.nano.2013.10.010.
Sevgi M, Toklu A, Vecchio D, Hamblin MR. Topical Antimicrobials for Burn Infections - an Update. Recent Pat Antiinfect Drug Discov. 2013 Dec;8(3):161-97.
de Melo Wde C, Lee AN, Perussi JR, Hamblin MR. Electroporation enhances antimicrobial photodynamic therapy mediated by the hydrophobic photosensitizer, hypericin. Photodiagnosis Photodyn Ther. 2013 Dec;10(4):647-50. doi: 10.1016/j.pdpdt.2013.08.001. Epub 2013 Sep 1. PMID:24284122
St Denis TG, Vecchio D, Zadlo A, Rineh A, Sadasivam M, Avci P, Huang L, Kozinska A, Chandran R, Sarna T, Hamblin MR. Thiocyanate potentiates antimicrobial photodynamic therapy: In situ generation of the sulfur trioxide radical anion by singlet oxygen. Free Radic Biol Med. 2013 Dec;65:800-10. doi: 10.1016/j.freeradbiomed.2013.08.162.
Hamblin MR. Can osteoarthritis be treated with light? Arthritis Res Ther. 2013 Oct 29;15(5):120. doi: 10.1186/ar4354. PMCID: PMC3978432
Tan A, Farhatnia Y, Goh D, G N, de Mel A, Lim J, Teoh S-H, Malkovskiy AV, Chawla R, Rajadas J, Cousins BG, Hamblin MR, Alavijeh MS, Seifalian AM. Surface modification of a polyhedral oligomeric silsesquioxane poly(carbonate-urea) urethane (POSS-PCU) nanocomposite polymer as a stent coating for enhanced capture of endothelial progenitor cells. Biointerphases. 2013, 8:23. http://www.biointerphases.com/content/8/1/23. PMCID: PMC3979469
Yin R, Wang M, Huang YY, Huang HC, Avci P, Chiang LY, Hamblin MR. Photodynamic therapy with decacationic [60]fullerene monoadducts: effect of a light absorbing electron-donor antenna and micellar formulation. Nanomedicine NBM. 2013 Dec 9. pii: S1549-9634(13)00679-5. doi: 10.1016/j.nano.2013.11.014. [Epub ahead of print] PMID 24333585
Huang L, Wang M, Sharma SK, Sperandio FF, Maragani S, Nayka S, Chang J, Hamblin MR, Chiang LY. Decacationic [70]Fullerene Approach for Efficient Photokilling of Infectious Bacteria and Cancer Cells. ECS Trans. 2013;45(20). doi: 10.1149/04520.0065ecst. PMCID: PMC3880553
Rineh A, Kelso MJ, Vatansever F, Tegos GP, Hamblin MR. Clostridium difficile infection: molecular pathogenesis and novel therapeutics. Expert Rev Anti Infect Ther. 2014 Jan;12(1):131-50. doi: 10.1586/14787210.2014.866515
Jimenez JJ, Wikramanayake TC, Bergfeld W, Hordinsky M, Hickman JG, Hamblin MR, Schachner LA. Efficacy and Safety of a Low-level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-controlled, Double-blind Study. Am J Clin Dermatol. 2014 Apr;15(2):115-27. doi: 10.1007/s40257-013-0060-6. PMCID: PMC3986893
Vecchio D, Bhayana B, Huang L, Carrasco E, Evans CL, Hamblin MR. Structure-function relationships of Nile blue (EtNBS) derivatives as antimicrobial photosensitizers. Eur J Med Chem, 2014 Mar 21;75:479-91. doi: 10.1016/j.ejmech.2014.01.064.
Wachowska M, Gabrysiak M, Muchowicz A, Bednarek W, Barankiewicz J, Rygiel T, Boon L, Mroz P, Hamblin MR, Golab J. 5-Aza-2’-deoxycytidine potentiates antitumour immune response induced by photodynamic therapy. Eur J Cancer, 2014 May;50(7):1370-81. doi: 10.1016/j.ejca.2014.01.017.
Naeser MA, Zafonte R, Krengel MH, Martin P, Frazier J, Hamblin MR, Knight JA, Meehan W, Baker EH. Significant improvements on cognitive performance post- transcranial, red/near-infrared LED treatments in chronic, mild TBI: Open-protocol study. J Neurotrauma. 2014 Feb 25. [Epub ahead of print]
Reginato E, Wolf P, Hamblin MR. Immune response after photodynamic therapy increases anti-cancer and anti-bacterial effects. World J Immunol. 2014 March 27; 4(1): 1-11
Golberg A, Broelsch GF, Vecchio D, Khan S, Hamblin MR, Austen, Jr. WJ , Sheridan RL, Yarmush ML. Eradication of multidrug-resistant A. baumannii in burn wounds by pulsed electric fields. Technology, 2014, in press
de Sousa MV, Ferraresi C, de Magalhães AC, Yoshimura EM, Hamblin MR. Building, testing and validating a set of home-made von Frey filaments: A precise, accurate and cost effective alternative for nociception assessment. J Neurosci Methods. 2014 May 2. pii: S0165-0270(14)00133-2. doi: 10.1016/j.jneumeth.2014.04.017. [Epub ahead of print]
Arany PR, Cho A, Hunt TD, Sidhu G, Shin K, Hahm E, Huang GX, Weaver J, Chen AC, Padwa BL, Hamblin MR, Barcellos-Hoff MH, Kulkarni AB, J Mooney D. Photoactivation of Endogenous Latent Transforming Growth Factor-β1 Directs Dental Stem Cell Differentiation for Regeneration. Sci Transl Med. 2014 May 28;6(238):238ra69. doi: 10.1126/scitranslmed.3008234.
Zhang Q, Zhou C, Hamblin MR, Wu MX. Low-level laser therapy effectively prevents secondary brain injury induced by immediate early responsive gene X-1 deficiency. J Cereb Blood Flow Metab. 2014 Aug;34(8):1391-401. doi: 10.1038/jcbfm.2014.95.
Sabino CP, Garcez AS, Núñez SC, Ribeiro MR, Hamblin MR. Endodontic photoinactivation of Candida albicans biofilm in curved root canals comparing two light delivery systems in real-time. Lasers Med Sci, 2014, in press
Kasimova K, Sadasivam M, Landi G, Sarna T, Hamblin MR, Potentiation of photoinactivation of Gram-positive and Gram-negative bacteria mediated by six phenothiazinium dyes by addition of azide ion. Photochem. Photobiol. Sci., 2014, DOI:10.1039/C4PP00021H.
Golberg A, Broelsch GF, Vecchio D, Khan S, Hamblin MR, Austen WG Jr, Sheridan RL, Yarmush ML. Pulsed Electric Fields for Burn Wound Disinfection in a Murine Model. J Burn Care Res. 2014 Aug 27. [Epub ahead of print]
Sperandio FF, Simões A, Corrêa L, Aranha ACC, Giudice FS, Hamblin MR, Sousa SCOM. Low-level laser irradiation promotes the proliferation and maturation of keratinocytes during epithelial wound repair. J Biophotonics, 2014, in press.
Xuan W, Agrawal T, Huang L, Gupta GK, Hamblin MR. Low-level laser therapy for traumatic brain injury in mice increases brain derived neurotrophic factor (BDNF) and synaptogenesis. J Biophotonics 2014, epub doi: 10.1002/jbio.201400069.
Xuan W. Vatansever F, Huang L, Hamblin MR. Transcranial low-level laser therapy enhances learning, memory and neuroprogenitor cells after traumatic brain injury in mice. J Biomedical Optics, 2014, 19(10), 108003 (2014). doi:10.1117/1.JBO.19.10.108003. Peer Reviewed Reviews
Hamblin MR, Newman EL. New trends in photobiology: on the mechanism of the tumour-localising effect in photodynamic therapy. J Photochem Photobiol B 1994;23(1):3-8.
Demidova TN, Hamblin MR. Macrophage targeted photodynamic therapy. Int J Immunopathol Pharmacol 2004; 17(2):117-26. PMC3071048
Demidova TN, Hamblin MR. Photodynamic therapy targeted to pathogens. Int J Immunopathol Pharmacol 2004;17(3): 245-54. PMC3071683
Castano AP, Demidova TN, Hamblin MR. Mechanisms in photodynamic therapy: part one - photosensitizers, photochemistry and cellular localization. Photodiagn Photodyn Ther 2004;1: 279-93.
Castano AP, Demidova TN, Hamblin MR. Mechanisms in photodynamic therapy: part two -cellular signaling, cell metabolism and modes of cell death. Photodiagn Photodyn Ther, 2005, 2:1-23.
Castano AP, Demidova TN, Hamblin MR. Mechanisms in photodynamic therapy: part three - photosensitizer pharmacokinetics, biodistribution, tumor localization and modes of tumor destruction. Photodiagn Photodyn Ther, 2005, 2: 91-106.
Castano AP, Mroz P, and Hamblin MR. Photodynamic therapy and anti-tumour immunity. Nat Rev Cancer, 2006, 6: 535-545. PMC2291083
Mroz P, Tegos GP, Gali H, Wharton T, Sarna T, Hamblin MR, Photodynamic therapy with fullerenes, Photochem Photobiol Sci, 2007, 6, 1139 – 1149. PMC2933422
Dai T, Huang Y-Y, Hamblin MR. Photodynamic therapy for localized infections – state of the art. Photodiagn Photodyn Ther. 2009, 6, 170-188. PMC2811240
Dai T, Huang YY, Sharma SK, Hashmi JT, Kurup DB Hamblin MR. Topical Antimicrobials for Burn Wound Infections. Recent Pat Antiinfect Drug Discov.2010, 5(2):124-51. PMC2935806
Hashmi JT, Huang Y-Y, Sharma SK, Kurup DB, De Taboada L, Carroll JD, Hamblin MR. Effect of pulsing in low-level light therapy. Laser Surg Med, 2010, 42:450–466. PMC2933784
Mroz P. Hashmi JT, Huang YY, Lange N, Hamblin MR. Stimulation of anti-tumor immunity by photodynamic therapy. Expert Rev Clin Immunol, 2011. 7(1): p. 75-91. PMC3060712
Hashmi JT, Huang YY, Osmani BZ, Sharma SK, Naeser MA, Hamblin MR. Role of Low Level Laser Therapy in Neurorehabilitation. Phys Med Rehabil, 2010, 2:S292-S305. PMC3065857
Mroz P, Hamblin MR. The immunosuppressive side of PDT. Photochem Photobiol Sci, 2011, May 1;10(5):751-8. PMC3441049
St. Denis TG, Aziz K, Waheed AA, Huang YY, Sharma SK, Mroz P, Hamblin MR. Combination approaches to potentiate immune response after photodynamic therapy for cancer. Photochem Photobiol Sci, 2011 May 1;10(5):792-801. PMC3449163
Sharma SK, Dai T, Kharkwal GB, Huang YY, Huang L, De Arce VJ, Tegos GP, Hamblin MR. Drug discovery of antimicrobial photosensitizers using animal models. Curr Pharm Des. 2011;17(13):1303-19. PMC3463379
Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, Korbelik M, Moan J, Mroz P, Nowis D, Piette J, Wilson BC, Golab J. Photodynamic Therapy Of Cancer: An Update. CA - A Cancer Journal for Physicians, 2011, Jul-Aug; 61(4):250-81 doi: 10.3322/caac.20114. PMC3209659
Dai, T., Kharkwal GB, Tanaka M, Huang YY, Bil de Arce VJ, Hamblin MR. Animal models of external traumatic wound infections. Virulence. 2011. 2:(4), 296-315; PMC3173676
Naeser MA, Hamblin MR. Potential for Transcranial Laser or LED Therapy to Treat Stroke, Traumatic Brain Injury, and Neurodegenerative Disease. Photomed Laser Surg. 2011, 29(7); 443-446. PMC3128319
Dai T, Tanaka M, Huang YY, Hamblin MR. Chitosan preparations for wounds and burns: antimicrobial and wound healing effects. Expert Rev Anti-Infect Ther. 2011, 9(7):857-879. PMC3188448
St. Denis TG, Dai T, Izikson A, Astrakas C, Anderson RR, Hamblin MR, Tegos GP. All you need is light. Antimicrobial photoinactivation as an evolving and emerging discovery strategy against infectious disease. Virulence, 2011, 2(6): 1-12. PMC3322354
Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The nuts and bolts of low-level laser (light) therapy, Ann Biomed Eng, 2012, 40(2):516-33. DOI: 10.1007/s10439-011-0454-7.
Kharkwal GB, Sharma SK, Huang YY, Dai T, Hamblin MR. Photodynamic Therapy for Infections: Clinical Applications. Lasers Surg Med, 2011 43:755–767 (2011) PMC3449167
Vera DM, Haynes MH, Ball AR, Dai T, Astrakas C, Kelso MJ, Hamblin MR, Tegos GP. Strategies to potentiate antimicrobial photoinactivation by overcoming resistant phenotypes. Photochem Photobiol, 2012 Jan 88(3):499-511. doi: 10.1111/j.1751-1097.2012.01087.x
Dai T, Vrahas MS, Murray CK, Hamblin MR. Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections? Expert Rev Anti-Infect Ther. (2012), 10(2), 185-195, PMC3292282
Huang YY, Gupta A, Vecchio D, Arce VJ, Huang SF, Xuan W, Hamblin MR. Transcranial low level laser (light) therapy for traumatic brain injury. J Biophotonics. 2012 Nov;5(11-12):827-37. doi: 10.1002/jbio.201200077.
Demidova-Rice TN, Hamblin MR, Herman IM. Acute and Impaired Wound Healing: Pathophysiology and Current Methods for Drug Delivery, Part 1: Normal and Chronic Wounds: Biology, Causes, and Approaches to Care. Adv Skin Wound Care, 2012; 25:304– 14
Demidova-Rice TN, Hamblin MR, Herman IM. Acute and Impaired Wound Healing: Pathophysiology and Current Methods for Drug Delivery, Part 2: Role of Growth Factors in Normal and Pathological Wound Healing: Therapeutic Potential and Methods of Delivery. Adv Skin Wound Care. 2012 Aug;25(8):349-370.
Dai T, Gupta A, Murray CK, Vrahas MS, Tegos GP, Hamblin MR. Blue light for infectious diseases: Propionibacterium acnes, Helicobacter pylori, and beyond? Drug Resist Updat. 2012 Aug;1 5(4):223-36.
Huang YY, Tanaka M, Vecchio D, Garcia-Diaz M, Chang J, Morimoto Y, Hamblin MR. Photodynamic therapy induces an immune response against a bacterial pathogen. Expert Rev Clin Immunol. 2012 Jul;8(5):479-94.
Gupta A, Avci P, Sadasivam M, Chandran P, Parizotto N, Vecchio D, Antunes-Melo WC, Dai T, Chiang LY, Hamblin MR. Shining Light on Nanotechnology to Help Repair and Regeneration Biotechnol Adv, 2012, http://dx.doi.org/10.1016/j.biotechadv.2012.08.003
Avci P, Sadasivam M, Gupta A, De Melo WC, Huang YY, Yin R, Chandran R, Kumar R, Otufowora A, Nyame T, Hamblin MR. Animal models of skin disease for drug discovery. Expert Opin Drug Discov. 2013 Mar;8(3):331-55. doi: 10.1517/17460441.2013.761202
Ferraresi C, Hamblin MR, Parizotto NA. Low-level laser (light) therapy (LLLT) on muscle tissue: performance, fatigue and repair benefited by the power of light. Photonics Lasers Med. 2012 Nov 1;1(4):267-286.
Vatansever F, Ferraresi C, de Sousa MV, Yin R, Rineh A, Sharma SK, Hamblin MR. Can biowarfare agents be defeated with light? Virulence. 2013 Sep 25;4(8). [Epub ahead of print] Review. PMID: 24067444
Huang YY, Sharma SK, Yin R, Agrawal T, Chiang LY, Hamblin MR. Functionalized Fullerenes in Photodynamic Therapy. J Biomed. Nanotechnol. 2014, 10, 1918–1936.
Avci P, Erdem SS, Hamblin MR. Photodynamic Therapy: One Step Ahead with Self-Assembled Nanoparticles. J Biomed. Nanotechnol. 2014, 10, 1937–1952.
Hu Z, Oleinick N, Hamblin MR. Photodynamic Therapy as an Emerging Treatment Modality for Cancer and Non-Cancer Diseases. J Anal Bioanal Tech S1: e001. doi:10.4172/2155-9872.S1-e001
Full -Length Proceedings Of Meetings
Hamblin MR, Newman EL. Conjugates between proteins and fluorescent dyes as potential photosensitizers. In: dal Fante M, Spinelli P, Marchesini R, editors. Photodynamic Therapy and Biomedical Lasers. Proceedings of the International Conference on Photodynamic Therapy and Medical Laser Applications; Sep 4-10, 1992 Milan, Italy. Amsterdam: Elsevier; 1992. p. 518-20.
Soukos NS, Hamblin MR, Deutsch TF, Hasan T. Monoclonal antibody-tagged receptor-targeted contrast agents for detection of cancers. In: Bearman GH; Bornhop DJ; Levenson RM; Editors. Biomarkers and Biological Spectral Imaging, Jan 19-23, 2001, Bellingham, WA, The International Society for Optical Engineering,Proceedings of SPIE; 2001. Vol 4259 p. 115-28.
Hamblin MR, O’Donnell DA, Zahra T, Contag CH, McManus AT, Hasan T. Targeted photodynamic therapy for infected wounds in mice. In: Dougherty TJ editor, Optical methods for tumor treatment and detection: Methods and techniques in Photodynamic therapy XI, Jan 20-24, 2002, Bellingham, WA, The International Society for Optical Engineering, Proceedings of SPIE; 2002. Vol 4612: p.48-58.
Hamblin MR, O’Donnell DA, Huzaira M, Zahra T. Scavenger receptor-targeted photodynamic therapy of J774 tumors in mice: tumor response and concomitant immunity. (Invited paper). In: Jacques SL, Duncan DD, Kirkpatrick SJ, Kriete A, editors, Laser Tissue Interaction XIV: Photochemical, Photothermal, and Photomechanical, Jan 25-31, 2002, Bellingham, WA, The International Society for Optical Engineering, Proceedings of SPIE; 2002. Vol 4617: p. 1-10.
Castano AP, Gad F, Zahra T, Hamblin MR. Specific anti-tumor immune response with photodynamic therapy mediated by benzoporphyrin derivative and chlorin(e6). (Invited paper) In: Jacques SL, Duncan DD, Kirkpatrick SJ, Kriete A, editors, Laser Tissue Interaction XIII: Photochemical, Photothermal, and Photomechanical, Jan 25-31, 2003, Bellingham, WA, The International Society for Optical Engineering, Proceedings of SPIE; 2003, Vol 4612: p 1-9
Hamblin MR, Tawakol A. Castano AP, Gad F, Zahra T, Ahmadi A, Stern J, Ortel B, Chirico S, Shirazi A, Syed S Muller JE. Macrophage-targeted photodynamic detection of vulnerable atherosclerotic plaque. In: Gregory KW, Whittaker P, Woodburn KW Editors, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems, Jan 25-31 2003, Bellingham, WA, The International Society for Optical Engineering, Proceedings of SPIE; 2003, Vol 4949: p 466-476.
Gad F, Zahra T, Hasan T, and Hamblin MR. Targeted photodynamic therapy of established soft-tissue infections in mice. In: Kessel D, Editor, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XIII, Jan 24-29 2004, Bellingham, WA, The International Society for Optical Engineering, Proceedings of SPIE, 2004; Vol 5315:p 63-75.
Castano AP, Liu Q, and Hamblin MR. Photodynamic therapy cures green fluorescent protein expressing RIF1 tumors in mice. In: Jaques SL, Roach WP Editors, Laser Interaction with Tissue and Cells XV, Jan 24-29 2004, Bellingham, WA, The International Society for Optical Engineering, Proceedings of SPIE, 2004; Vol 5319: p 50-59.
Hamblin MR, Gad F, Anderson RR, Hasan T. Photons for therapy: Targeted photodynamic therapy for infected and contaminated wounds. NATO Research and Technology Organisation Symposium: Combat Casualty Care in Ground Based Tactical Situations: Trauma Technology and Emergency Medical Procedures. HFM-109 /RSY organised by the Human Factors and Medicine Panel in cooperation with the US Department of Defense Advanced Technology Applications for Combat Casualty Care Conference.
Castano AP and Hamblin MR. Anti-tumor immunity generated by photodynamic therapy in a metastatic murine tumor model. In: Jaques SL, Roach WP Editors, Laser Interaction with Tissue and Cells XVI, Jan 21-26 2005, Bellingham, WA, The International Society for Optical Engineering, Proceedings of SPIE, 2005; Vol 5695:p 7-16.
Demidova TN and Hamblin MR. Anthrax surrogate spores are destroyed by PDT mediated by phenothiazinium dyes. In: Kessel D, Editor, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy, XIV Jan 21-26 2005, Bellingham, WA, The International Society for Optical Engineering, Proceedings of SPIE, 2005; Vol 5689: p 66-77.
Koshiyama K, Kodama T, Hamblin MR, Doukas AG, Yano T, Fujikawa S. Molecular Delivery into a Lipid Bilayer with a Single Shock Wave Using, Molecular Dynamics Simulation. American Institute of Physics Conference Proceedings, 2005, Vol 754, 104-106
Castano AP and Hamblin MR. Enhancing photodynamic therapy of a metastatic mouse breast cancer by immune stimulation. In: Chen WR, Editor. Biophotonics and Immune Responses. Jan 20-25 2006, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6087. art. no. 608703
Hamblin MR, Castano AP and Mroz P. Combination immunotherapy and photodynamic therapy for cancer. In: Chen WR, Editor. Biophotonics and Immune Responses. Jan 20-25 2006, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6087 art. no. 608702.
Hamblin MR, Demidova TN. Mechanisms of Low Level Light Therapy – an Introduction. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy Jan 20-25 2006, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6140. art. no. 61001 1-12
Demidova TN, Herman IN, Salomantina EV, Yaroslavsky AN, Hamblin MR. Wound healing stimulation in mice by low level light. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy Jan 20-25 2006, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6140. art. no.61400C 1-9.
Hamblin MR,. Demidova-Rice TN, Castano AP, Dai T, Yaroslavsky I, Cohen R, Apruzzese AW, Smotrich MH, Low-level light therapy for wound healing and arthritis in animal models. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy II, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6428. 2007; DOI: 10.1117/12.712885.
Hamblin MR, Demidova-Rice TN. Cellular chromophores and signaling in LLLT. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy II, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6428. 2007; DOI: 10.1117/12.712885.
Mroz P, Castano AP. Wu MX, Kung AL, Hamblin MR. Photodynamic therapy stimulates anti-tumor immunity in murine models. In: Chen WR, Editor; Biophotonics and Immune Responses II, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6438. 2007; DOI: 10.1117/12. 697630.
Eduardo FP, Mehmert DU, Monezi TA, Zezell DM, Schubert MM, Eduardo CP, Marques MM, Hamblin MR, Waynant RW, Anders J. In vitro effect of phototherapy with low intensity laser on HSV-1 and epithelial cells - art. no. 642805. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy II, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE vol 6428; 2007; 42805;
Yaroslavsky AN, Salomatina E, Novak J, Amat-Roldan; I, Castano AP, Hamblin MR. Dye-enhanced reflectance and fluorescence confocal microscopy as an optical pathology tool. In Optical Biopsy VI, Alfano RR, Katz A, Editors, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6091, 2007, DOI: 10.1117/12.658303
Mroz P, Hamblin MR. Photodynamic therapy stimulates anti-tumor immunity in a murine mastocytoma model. In: Chen WR, Editor; Biophotonics and Immune Responses III, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 6847, 2008; DOI: 10.1117/12.764922.
Hamblin MR. The role of nitric oxide in low level light therapy. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy III, Bellingham, WA, The International Society for Optical Engineering,. Proc SPIE 6846, 2008; DOI: 10.1117/12.764918
Garcez, AS, Núñez, SC, Hamblin, MR, Ribeiro, MS, Antimicrobial comparison on effectiveness of endodontic therapy and endodontic therapy combined with photo-disinfection on patients with periapical lesion: a 6 month follow-up. In Mechanisms for Low-Light Therapy III, edited by Michael R. Hamblin, Ronald W. Waynant, Juanita Anders, Proceedings of SPIE Vol. 6846 (SPIE, Bellingham, WA 2008) 68460G.
Chen AC-H, Arany PR, Huang Y-Y, Tomkinson EM, Saleem T, Yull FE, Blackwell TS, Hamblin MR. Low level laser therapy activates NF-kB via generation of reactive oxygen species in mouse embryonic fibroblasts. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy IV, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE Vol. 7165, 71650B. 2009. doi: 10.1117/12.809605
Chen AC-H, Huang Y-Y, Arany PR, Hamblin MR. Role of reactive oxygen species in low level light therapy. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy IV, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE Vol. 7165, 716502, 2009. doi: 10.1117/12.814890
Mroz P, Castano AP, Hamblin MR. Stimulation of dendritic cells enhances immune response after photodynamic therapy. In: Chen WR, Editor; Biophotonics and Immune Responses III, Bellingham, WA, The International Society for Optical Engineering, Proc. SPIE Vol. 7178, 717803, 2009. doi: 10.1117/12.809630
Arany PR, Chen AC-H, Hunt T, Mooney D, Hamblin MR. Role of ROS-mediated TGF beta activation in laser photobiomodulation. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy IV, Bellingham, WA, The International Society for Optical Engineering,. Proc SPIE Vol. 7165, 71650C, 2009. doi: 10.1117/12.809839
Mroz P, Huang Y-Y, Janjua S, Zhiyentayev T, Ruzié C, Borbas KE, Fan D, Krayer M, Balasubramanian T, Kang EK, Kee HL, Holten D, Lindsey JS, and Hamblin MR. New stable synthetic bacteriochlorins for photodynamic therapy of melanoma. In Photodynamic Therapy: Back to the Future, edited by David H. Kessel, Proc. of SPIE Vol. 7380, 73802S, doi: 10.1117/12.823060
Mroz P, Castano AP, Wu MX, Kung AL and Hamblin MR. Anti-tumor immune response after photodynamic therapy In Photodynamic Therapy: Back to the Future, edited by David H. Kessel, Proc. of SPIE Vol. 7380, 73800F, doi: 10.1117/12.822994
Mroz P and Hamblin MR. Combination of PDT and a DNA demethylating agent produces anti-tumor immune response in a mouse tumor model. In Photodynamic Therapy: Back to the Future, edited by David H. Kessel, Proc. of SPIE Vol. 7380, 73800H, doi: 10.1117/12.823005
Dai T, Tegos GP, Lu Z, Zhiyentayev T, Huang L, Franklin MF, Baer DG and Hamblin MR. Antimicrobial photodynamic therapy in a mouse model of Acinetobacter baumannii burn infection, In Photodynamic Therapy: Back to the Future, edited by David H. Kessel, Proc. of SPIE Vol. 7380, 738037, doi: 10.1117/12.823065
Upadya MH, Tegos GP, Hamblin MR, and Kishen A. Influence of bacterial interactions on the susceptibility to photodynamic inactivation. In Photodynamic Therapy: Back to the Future, edited by David H. Kessel, Proc. of SPIE Vol. 7380, 73803D, doi: 10.1117/12.822851
Wu Q, Huang Y-Y, Dhital S, Sharma SK, Chen A C-H, Whalen MJ, Hamblin MR. Low level laser therapy for traumatic brain injury. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy V, Bellingham, WA, The International Society for Optical Engineering. Proc SPIE 2010, Vol. 7552: 755206-1
Huang Y-Y, Chen AC-H, Wu Q, Sharma SK, Hamblin MR. Comparison of cellular responses induced by low level light in different cell types. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy V, Bellingham, WA, The International Society for Optical Engineering,. Proc SPIE 2010, Vol. 7552: 75520A-1
Mroz P, Huang Y-Y, Hamblin MR. Photodynamic therapy for cancer and activation of immune response. In: Chen WR, Editor; Biophotonics and Immune Responses V, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 2010, Vol. 7565, 756503-1
Chen AC-H, Huang Y-Y, Sharma SK, Hamblin MR. Can dendritic cells see light?. In: Chen WR, Editor; Biophotonics and Immune Responses V, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 2010, Vol. 7565, 756504-1
Naeser MN, Saltmarche A, Krengel MH, Hamblin MR, Knight JA. Transcranial LED therapy for cognitive dysfunction in chronic, mild traumatic brain injury: Two case reports. In Hamblin, M.R., Anders, J.J. and Waynant, R.W., eds. Mechanisms for Low-Light Therapy V, The International Society for Optical Engineering., Bellingham, WA,. Proc SPIE 2010, Vol. 7552, 75520L-1
Kharkwal GB, Sharma SK, Huang YY, De Taboada L, McCarthy T, Hamblin MR. Effects of 810 nm laser on mouse primary cortical neurons. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy VI, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 2011. Vol 7887, 788702
Kato IT Prates RA, Tegos GP, Hamblin MR, Ribeiro MS. Oxidative stress of photodynamic antimicrobial chemotherapy inhibits Candida albicans virulence. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy VI, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 2011. Vol 7887, 788706
Prates RA, Hamblin MR, Kato IT, Fuchs B, Mylonakis E, Ribeiro MS. Tegos GP. Cryptococcus neoformans capsule protects cell from oxygen reactive species generated by antimicrobial photodynamic inactivation. In: Hamblin MR, Anders JJ, Waynant RW, Editors. Mechanisms for Low-Light Therapy VI, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 2011. Vol 7887, 788704
Mroz P, Hamblin MR. The potential role of functional inhibition of T regulatory cells by anti-TGFβ antibody in photodynamic therapy of renal cancer. In: Chen WR, Editor; Biophotonics and Immune Responses VI, Bellingham, WA, The International Society for Optical Engineering, Proc. SPIE 2011, Vol 7900, 790003
St. Denis, TG, Huang, L, Kishen, A, Prates, RA, Tegos, GP, Hamblin, MR. Antimicrobial Photodynamic Therapy: Can Resistance Develop? In Kostron H, editor; Proceedings of the 13th IPA World Conference, Medimond International Proceedings, Bologna, Italy, 2011.
Xuan W, Wu Q, Huang YY, Ando T, Huang L, Hamblin MR. In vivo studies of low level laser (light) therapy for traumatic brain injury. In : Hamblin MR, Anders JJ, Carroll J, Editors. Mechanisms for Low-Light Therapy VII, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 2012
Huang YY, Tedford CE, McCarthy T, Hamblin MR. Low level laser therapy reduces oxidative stress in cortical neurons in vitro. In : Hamblin MR, Anders JJ, Carroll J, Editors. Mechanisms for Low-Light Therapy VII, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 2012
Tanaka M, Mroz P, Dai T, Kinoshita T, Morimoto Y, Hamblin MR. Photodynamic therapy can induce non-specific protective immunity against a bacterial infection. In: Chen WR, Editor; Biophotonics and Immune Responses VII, Bellingham, WA, The International Society for Optical Engineering, Proc. SPIE 2012
Vatansever F, Hamblin MR. Transcranial low-level laser (light) therapy: mechanisms and application to traumatic brain injury and beyond. Proceedings of the 9th WALT Congress (September 28-30, 2012, QT Gold Coast, Surfers Paradise, Australia). Medimond International Proceedings, Bologna, Italy. pp73-80.
Vatansever F, Kawakubo M, Chung H, Hamblin MR. Photodynamic therapy stimulates anti-tumor immune response in mouse models: the role of regulatory T-cells, anti-tumor antibodies, and immune attack on brain metastases. In: Chen WR, Editor; Biophotonics and Immune Responses VIII, Bellingham, WA, The International Society for Optical Engineering, Proc. SPIE 2013
Vatansever F, Xuan W, Huang YY, Hamblin MR. Transcranial low-level light therapy produces neuroprotection, neurogenesis and BDNF after TBI in mice. In: Hamblin MR, Carroll J, Arany, P. Editors. Mechanisms for Low-Light Therapy VIII, Bellingham, WA, The International Society for Optical Engineering, Proc SPIE 2013
Sawhney MK, Hamblin MR. Low level light therapy in aesthetic dermatology. In: Hamblin MR, Carroll J, Arany, P. Editors. Mechanisms for Low-Light Therapy IX, 2014. Proc. of SPIE Vol. 8932, 89320X.
Avci P, Gupta GK, Kawakubo M, Hamblin MR. Photodynamic therapy for melanoma: efficacy and immune response. In: Chen WR, Editor; Biophotonics and immune responses IX 2014. Proc. of SPIE Vol. 8944 894403-1
Jorge AES, Hamblin MR, Parizotto NA, Kurachi C, Bagnato VS. Photodynamic therapy improves the ultraviolet-irradiated hairless mice skin. In Choi B, Kollias N, Zeng H, Editors. Photonics in Dermatology and Plastic Surgery. 2014. Proc. of SPIE Vol. 8926 89260N-1.
Feng X, Huang YY, Patel R, Wirth DJ, Hamblin MR, Yaroslavsky AN. Detecting breast cancer in single cells. In Alfano RR, Demos SG, Editors. Optical Biopsy XII. 2014. Proc. of SPIE

Non-peer reviewed scientific or medical publications/materials in print or other media
Reviews and Book Chapters

Hamblin MR, Hasan T. Advances in photodynamic therapy. Optics and Photonic News 1996;7(7):16-21.
Hamblin MR, Ortel B. Future directions: Photosensitizer targeting and new disease indications. In: Hader DM, Jori G, series editors. Comprehensive series in photosciences. Amsterdam, Netherlands: Elsevier Science, BV; 2001. p. 339-66. (Calzavara-Pinton PG, Ortel B, Szeimies RM, volume editors. Photodynamic therapy and fluorescence diagnosis in dermatology; vol. 2.)
Hamblin MR. Covalent photosensitizer conjugates for targeted photodynamic therapy. Trends in Photochem Photobiol 2002;9:1-24.
Hamblin MR. Photodynamic therapy. In: Syrigos KN and Harrington K, editors. Targeted therapy for cancer. Oxford UK: Oxford University Press; 2003. p. 259-72.
Hamblin MR, Mroz P, Tegos GP, Gali H, Wharton T, Sarna T, Pawlak A. Photodynamic therapy with fullerenes. In: Carl N. Kramer, editor; Fullerene Research Trends, Nova Science Publishers, Inc, Hauppauge, NY, 2008.
Mroz P, Tegos GP, Gali H, Wharton T, Sarna T, Hamblin MR. Fullerenes as Photosensitizers in Photodynamic Therapy. In: Franco Cataldo and Tatiana Da Ros, editors; Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes (Carbon Materials: Chemistry and Physics). Springer Science+Business Media Deutschland GmbH, Berlin, Germany, 2008, ISBN-13: 978-1402068447
Hamblin MR, Mroz P. Lasers in Photodynamic Therapy. In: Maximilian Lackner, editor; Lasers in Chemistry, VCH Wiley Verlag GmbH & Co., Weinheim, Germany, 2008, ISBN-13: 978-3527319978
Hamblin MR, Mroz P. History of PDT: The First Hundred Years. In: Hamblin MR and Mroz P. editors; Advances in Photodynamic Therapy: Basic, Translational and Clinical, Artech House, Inc, Norwood, MA: 2008. ISBN-13 978-1-59693-277-7.
Hamblin MR, Covalent Photosensitizer Conjugates. Part 1: Antibodies and Other Proteins for Targeted Photodynamic Therapy. In: Hamblin MR and Mroz P. editors; Advances in Photodynamic Therapy: Basic, Translational and Clinical, Artech House, Inc, Norwood, MA: 2008. ISBN-13 978-1-59693-277-7.
Hamblin MR, Covalent Photosensitizer Conjugates Part 2: Peptides, Polymers and Small Molecules for Targeted Photodynamic Therapy. In: Hamblin MR and Mroz P. editors; Advances in Photodynamic Therapy: Basic, Translational and Clinical, Artech House, Inc, Norwood, MA: 2008. ISBN-13 978-1-59693-277-7.
Mroz P, Hamblin MR, PDT and Cellular Immunity. In: Hamblin MR and Mroz P. editors; Advances in Photodynamic Therapy: Basic, Translational and Clinical, Artech House, Inc, Norwood, MA: 2008. ISBN-13 978-1-59693-277-7.
Hamblin MR, Brown SB. Photodynamic Therapy for Infectious Disease. In: Hamblin MR and Mroz P. editors; Advances in Photodynamic Therapy: Basic, Translational and Clinical, Artech House, Inc, Norwood, MA: 2008. ISBN-13 978-1-59693-277-7.
Castano AP, Hamblin MR, PDT for Cardiovascular Disease. In: Hamblin MR and Mroz P. editors; Advances in Photodynamic Therapy: Basic, Translational and Clinical, Artech House, Inc, Norwood, MA: 2008. ISBN-13 978-1-59693-277-7.
Hamblin MR, Conclusion: Photodynamic Therapy—The Next Hundred Years. In: Hamblin MR and Mroz P. editors; Advances in Photodynamic Therapy: Basic, Translational and Clinical, Artech House, Inc, Norwood, MA: 2008. ISBN-13 978-1-59693-277-7.
Hamblin MR, Castano AP, Mroz P. Combination Immunotherapy and Photodynamic Therapy for Cancer. In: Waynant R and Tata DB editors; Proceedings of Light Activated Tissue Regeneration and Therapy Conference, Lecture Notes in Electrical Engineering Vol 12, Springer Science+Business Media Inc, New York NY, 2008. ISBN 978-0-387-71808-8
Hamblin MR, Photodynamic Therapy: A Systems Biology Approach. In: Daskalaki A, editor; Handbook of Research on Systems Biology Applications in Medicine. Information Science Reference IGI Global, Hershey PA, 2008. ISBN 978-1-60566-076-9
Huang YY, Chen AC-H, Hamblin MR, Low-level laser therapy: an emerging clinical paradigm, SPIE Newsroom. (2009) doi 10.1117/2.1200906.1669.
Mroz P, Huang Y-Y, Wharton T, Hamblin MR. Fullerenes in Photodynamic Therapy of Cancer. In: Sattler KD editor; Handbook of Nanophysics. Taylor and Francis Books Inc, Boca Raton FL. 2010. ISBN-978-1-4200-7546-5
Huang Y-Y, Chen A C-H, Hamblin M R. Advances in low intensity laser and phototherapy. In: Tuchin VV editor. Handbook of Photonics for Biomedical Science. Taylor and Francis Books Inc, Boca Raton FL. 2010. ISBN 978-1-4398-0628-9
Huang Y-Y, Hamblin MR, De Taboada L. Low level laser therapy for stroke and central nervous system disorders. In: Tuchin VV editor. Handbook of Photonics for Biomedical Science. Taylor and Francis Books Inc, Boca Raton FL. 2010. ISBN 978-1-4398-0628-9
Sharma SK, Huang Y-Y, Mroz P, Wharton T, Chiang LY, Hamblin MR. Fullerenes in Photodynamic Therapy. In Kumar C. editor, Volume 9. Nanomaterials for the Life Sciences (NmLS), Wiley-VCH, Berlin. 2010, ISBN 978-1-4398-0628-9
Huang L, Dai T, Hamblin MR. Antimicrobial photodynamic inactivation and photodynamic therapy for infections. In Gomer CJ editor, Photodynamic Therapy: Methods and Protocols. Methods in Molecular Biology Vol 635. Humana Press, Springer Science and Business Media. New York, NY. 2010. ISBN-
Huang YY, Wu Q, Xuan W, Ando T, Xu T, Sharma SK, Kharkwal GB, Hamblin MR. Low Level Light Therapy Aids Traumatic Brain Injury. SPIE Newsroom. 2011. DOI: 10.1117/2.1201102.003573
St. Denis TG, Hamblin MR An Introduction to Photoantimicrobials: Photodynamic Therapy as a Novel Method of Microbial Pathogen Eradication. In Science against microbial pathogens: communicating current research and technological advances A. Méndez-Vilas (Ed.). Formatex. Research Center. Badajoz, Spain. 2011.
Sharma SK, Dai T, Hamblin MR. Antimicrobial Photosensitizers - Harnessing the Power of Light to Treat Infections. In Antimicrobial Drug Discovery Emerging Strategies. Tegos GP and Mylonakis E. Editors. CABI, Wallingford UK. 2011
Huang YY, Hamblin MR. Mechanisms of Low Level Light Therapy. In Laser de baixa potência - Princípios Básicos e aplicações clínicas na Odontologia. Nunez SC, Garcez-Segundo A, Ribeiro MS. Editors. Elsevier, Sao Paulo, Brazil, 2011.
Mroz P, Sharma SK, Zhiyentayev T, Huang YY, Hamblin MR. Photodynamic Therapy: Photosensitizer Targeting and Delivery. In: Drug Delivery in Oncology: From Basic Research to Cancer Therapy. Eds: Kratz F, Senter P, Steinhagen H. Pages: 1569–1603, 2011 Published Online: 2011, Wiley VCH Verlag GmbH DOI: 10.1002/9783527634057.ch48
Sharma SK, Huang YY, Mroz P, Wharton T, Chiang LY, Hamblin MR. Fullerenes in Photodynamic Therapy. In: Nanotechnologies for the Life Sciences. Ed: Kumar C. Published Online: 2012 Wiley VCH Verlag GmbH. DOI: 10.1002/9783527610419.ntls0244
St Denis TG, Dai T, Huang YY, Hamblin MR. Wound-Healing Properties of Chitosan and Its Use in Wound Dressing Biopharmaceuticals. In: Chitosan-Based Systems for Biopharmaceuticals: Delivery, Targeting and Polymer Therapeutics, Eds: Sarmento B, das Neves J. Published Online: 2012. Wiley VCH Verlag GmbH DOI: 10.1002/9781119962977.ch22
Ferraresi C, Huang YY, de Brito Vieira WH, Hamblin MR, Bagnato VS, Parizotto NA, Phototherapy by Low-Level Laser Therapy (LLLT) and Light-Emitting Diode Therapy (LEDT) for Improvement of Muscle Performance. In: Muscle Strength Development, Assessment and Role in Disease. Eds: Ferraresi C, Parizotto NA. 2013. Nova Science Publishers. Hauppauge, NY. ISBN: 978-1-62948-095-4

Books

Mechanisms for Low-Light Therapy I, edited by Hamblin MR, Waynant RW, Anders JJ, Proceedings of SPIE Vol. 6140 (SPIE, Bellingham, WA 2006). ISBN-13 978-0-8194-6183-4
Mechanisms for Low-Light Therapy II, edited by Hamblin MR, Waynant RW, Anders JJ, Proceedings of SPIE Vol. 6428 (SPIE, Bellingham, WA 2007). ISBN-13 978-0-8194-6541-2
Mechanisms for Low-Light Therapy III, edited by Hamblin MR, Waynant RW, Anders JJ, Proceedings of SPIE Vol 6846 (SPIE, Bellingham, WA 2008). ISBN-13 978-0-8194-7021-8
Advances in Photodynamic Therapy: Basic, Translational and Clinical, edited by Hamblin MR and Mroz P. Artech House, Inc, Norwood, MA: 2008. ISBN-13: 978-1-59693-277-7
Mechanisms for Low-Light Therapy IV, edited by Hamblin MR, Waynant RW, Anders JJ, Proceedings of SPIE Vol 7178 (SPIE, Bellingham, WA 2009). ISBN-13: 978-0-8194-7411-7
Mechanisms for Low-Light Therapy V, edited by Hamblin MR, Waynant RW, Anders JJ, Proceedings of SPIE Vol 7552 (SPIE, Bellingham, WA 2010) ISBN-13: 978-0-8194-7948-8
Mechanisms for Low-Light Therapy VI, edited by Hamblin MR, Waynant RW, Anders JJ, Proceedings of SPIE Vol 7887 (SPIE, Bellingham, WA 2011) ISBN-13 978-0-8194-8424-6
Photodynamic Inactivation of Microbial Pathogens: Medical and Environmental Applications, edited by Hamblin MR and Jori G. RSC Publishing, Cambridge, UK: 2011. ISBN-13: 978-1-84973-144-7
Mechanisms for Low-Light Therapy VII. edited by Hamblin MR, Anders JJ, Carroll JD. Proceedings of SPIE Vol 8211 (SPIE, Bellingham, WA 2012) ISBN-13: 978-0-8194-8854-1
Handbook of Photomedicine. Hamblin MR and Huang YY (Editors). Taylor and Francis (Oct 15, 2013) ISBN-13: 978-1-43988-469-0
Photodynamic Therapy Mediated by Fullerenes and their Derivatives. Sperandio FF, Gupta A, Wang M, Chandran R, Sadasivam M, Huang YY, Chiang LY, Hamblin MR. American Society of Mechanical Engineers/Momentum Press, 2012 ISBN-13: 978-0791860083.

The oxidation of some phenolic amines. PhD thesis defended in 1977 and awarded by the Council for National Academic Awards, UK.

Abstracts, Poster Presentations and Exhibits Presented at Professional Meetings

Hamrahi V, Hamblin MR, Carter EA, Benjamin J, Francis KP, Fischman AJ, Tompkins RG Role of Interleukin 6 (Il6) and Tumor Necrosis Factor (TNF) in Burn Eschar Bacterial Colonization and Wound Healing. J Burn Care Res 01/2006; 27.
Wu Q, Huang Y-Y, Dhital S, Sharma SK, Chen A C-H, Whalen MJ, Hamblin MR. Low level laser therapy for traumatic brain injury. Mechanisms for Low-Light Therapy V, Bios 2010, SPIE Photonics West, San Francisco, CA
Huang Y-Y, Chen AC-H, Wu Q, Sharma SK, Hamblin MR. Comparison of cellular responses induced by low level light in different cell types. Mechanisms for Low-Light Therapy V, Bios 2010, SPIE Photonics West, San Francisco, CA
Mroz P, Huang Y-Y, Hamblin MR. Photodynamic therapy for cancer and activation of immune response. Biophotonics and immune responses V. BioS 2010, SPIE Photonics West, San Francisco, CA
Chen AC-H, Huang Y-Y, Sharma SK, Hamblin MR. Can dendritic cells see light? Biophotonics and immune responses V. BioS 2010, SPIE Photonics West, San Francisco, CA
Naeser MN, Saltmarche A, Krengel MH, Hamblin MR, Knight JA. Transcranial LED therapy for cognitive dysfunction in chronic, mild traumatic brain injury: Two case reports. Mechanisms for Low-Light Therapy V, Bios 2010, SPIE Photonics West, San Francisco, CA
Spagnolli E, Anderson RR, Hamblin MR, Nagasaka Y, Bloch KD, Zapol WM. Protective effects of Red/Near Infrared Radiation on Murine Cardiac Ischemia/Reperfusion Injury. Experimental Biology 2010, Anaheim CA.FASEB J. 2010 24:lb410.
Hamblin MR, Naeser MN, Schiffer F, Wu Q, Huang YY, Transcranial laser therapy for acute and chronic traumatic brain injury. 35th Annual Meeting American Society for Photobiology. 2010, Providence RI.
Hamblin MR, Mroz P, Castano AP, Wu MX, Skokalska A. How to increase immune recognition of tumors after PDT. 35th Annual Meeting American Society for Photobiology. 2010, Providence RI.
Mroz P, Hamblin MR, The role of tumor antigens in PDT-mediated immune response. 35th Annual Meeting American Society for Photobiology. 2010, Providence RI.
Hamblin MR, Mroz P, Huang YY, Huang L, Balasubramanian T, Zhiyentayev T, Holten D, Bocian DF, Lindsey JS. Photodynamic Therapy with Stable Synthetic Bacteriochlorins. Sixth International Conference on Porphyrins and Phthalocyanines (ICPP-6), 2010, Santa Ana Pueblo, NM
Hamblin MR, Wu Q, Huang YY, Chen AC. Transcranial Low Level Light Therapy for Traumatic Brain Injury: In vitro and In vivo Studies. Light-Activated Tissue Regeneration and Therapy III. 2010, Burlington VT.
Hamblin MR. Laser and light therapy: mechanisms for the biphasic dose response in biological systems. WALT2010 8th Congress of World Association for Laser Therapy, Bergen Norway
Dai T, Huang L, Tegos GP, Huang YY, Sharma SK, Hamblin MR. Antimicrobial photodynamic therapy for localized infections in novel animal models. 8th Brixen PDT and PD Meeting 2010. Brixen, Italy
Mroz P, Hamblin MR. Photodynamic therapy and anti-T-reg strategies. Biophotonics and immune responses VI. Bios 2011, SPIE Photonics West, San Francisco, CA
Xuan W, Wu Q, Huang YY, Sharma SK, Ando, T, Xu T, Kharkwal GB, Whalen MJ, Hamblin MR. Low-Level Light Therapy for Traumatic Brain Injury. Mechanisms for Low-Light Therapy VI, Bios 2011, SPIE Photonics West, San Francisco, CA
Hamrahi V, Hamblin MR, Fischman AJ, Carter EA. Molecular Imaging of Burn Associated Sepsis Produced by Intraperitoneal Fibrin Clots Containing Bioluminescent Pseudomonas in Mice. Society of Nuclear Medicine SNM2011, San Antonio, TX, 2011
Hamrahi V, Hamblin MR, Fischman AJ, Carter EA. Imaging of Burn Induced Sepsis in Mice Produced by Gram Negative Bacteria Thigh Abscesses: Relationship To Burn Depth. Society of Nuclear Medicine SNM2011, San Antonio, TX, 2011
Hamrahi V, Hamblin MR, Fischman AJ, Carter EA. Evaluation of Antibiotic Resistant Staphylococcus aureus (MRSA) in Burn Eschar of Mice. Society of Nuclear Medicine SNM2011, San Antonio, TX, 2011
Fuchs BB, Tegos GP, Hamblin MR, Mylonakis E. Cryptococcus neoformans cell wall integrity provides defense to super oxides and ROS but not peroxide. 8th International Conference on Cryptococcus and Cryptococcosis (8th ICCC), Charleston, SC, 2011.
Fuchs BB, Tegos GP, Hamblin MR, Mylonakis E. Cryptococcus neoformans cell wall integrity provides defense to superoxide and photogenerated ROS but not hydrogen peroxide. Infectious Disease Society of America, IDSA 2011, Boston MA
Chiang LY, Hamblin MR. Decacationic [70]Fullerene Approach for Efficient Photokilling of Infectious Bacteria and Cancer Cells. 221st Electrochemical Society Meeting in Seattle, WA, 2012.
Sperandio FF, Sharma SK, Wang M, Huang YY, Dai T, Sousa SC, Chiang LY, Hamblin MR. PDT with C84 fullerenes: Excitation wavelengths and photochemical mechanisms. World Federation for Laser Dentistry, 2012, Barcelona, Spain.
Jeffrey Knight1,2,3 , Margaret Naeser 2,3 , Maxine Krengel 2,3 , Paula Martin,3, Ethan Treglia,3, Michael Ho,3, Judith Frazier 5 , Michael Hamblin 4 and Ross Zafonte Using an Innovative Photomedicine Intervention to Improve Functioning in PTSD and TBI. American Psychological Association Meeting, August, 2013, Hawaii,
Golberg A, Broelsch GF, Vecchio D, Khan S, Hamblin MR, Austen, Jr. G, Sheridan RL, Yarmush ML. Pulsed Electric Fields for burn wound disinfection in a murine model. American Burns Association ABA 46th Annual Meeting, 2014. Boston, MA

Michael Hamblin, PhD

Associate Professor of Dermatology
Harvard Medical School
Boston, Massachusetts, USA
Phone: 617-726-6182
E-mail:hamblin@helix.mgh.harvard.edu