Publications

  1. Ho WKK, Chan WY.  Serum lipid and lipoprotein levels in normal Chinese.  Clin Chim Acta. 7:149‑154, 1974.
  2. Ho WKK, Chan WY.  Evaluation of serum lipid and lipopro­tein levels in normal Chinese.  The influence of dietary habit, body weight, exercise and familial record of coronary heart disease.  Clin Chim Acta.  61:19‑ 25, 1975.
  3. Garnica AD, Chan WY, Rennert OM.  The role of the metal­lothioneins in intracellular copper transport:   Studies using skin fibroblasts of patients with Menkes' Syndrome.  Ann Clin Lab Sci. 8:302‑ 309, 1978.
  4. Chan WY, Garnica AD, Rennert OM.  Metal binding studies of metal­lo­thioneins in Menkes' Kinky Hair   Disease.  Clin Chim Acta. 88:221‑ 228, 1978.
  5. Chan WY, Garnica AD, Rennert OM.  Cell culture studies of Menkes' Kinky Hair Disease.  Clin Chim Acta.  88:495‑507, 1978.
  6. Chan WY, Seale TW, Shukla JB, Rennert OM.  Polyamine conjugates and total polyamine concentration in human amniotic fluid. Clin Chim Acta.  91:233‑242, 1979.
  7. Chan WY, Garnica AD, Rennert OM.  Inducibility of metallothionein biosynthesis in cultured normal and Menkes' Kinky Hair Disease fibroblasts:  Effects of copper and cadmium.  Pediat Res. 13(4):197‑203, 1979.
  8. Rennert OM, Chan WY.  Menkes' metallothionein and copper metabolism.  Pediat Res. 13(4):204‑­205,  1979.
  9. Seale TW, Chan WY, Shukla JB, Rennert OM.  Isolation and characterization of a polyamine‑peptide conjugate from human amniotic fluid.  Clin Chim Acta.  95:461‑472, 1979.
  10. Seale TW, Chan WY, Shukla JB, Rennert OM.  A polyamine-peptide conjugate isolated from normal human plasma.  Arch  Biochem Biophys. 189:164‑174, 1979.
  11. Chan WY, Seale TW, Rennert OM.  Fluorescence micro-disc electrophoresis in sodium dodecylsulfate: A  simple and sensitive method applicable for routine laboratory analysis.  J Chromat. 181(2):259­‑265, 1980.
  12. Chan WY, Cushing W, Coffman MA, Rennert OM.  Genetic expression of Wilson's Disease in cell culture: A diagnostic marker.  Science.  208:299‑300, 1980.
  13. Rennert OM, Chan WY, Hildago H, Cushing W, Griesmann GE.  Polyamines in Menkes' Kinky Hair Disease.  Clin Chim Acta. 103:375‑ 380, 1980.
  14. Chan WY, Rennert OM.  Comparative study of Menkes' and Wilson's Disease.  Cien Biol.  5(2):73‑75,    1980.
  15. Chan WY, Richichi J, Griesmann GE, Cushing W, Kling OR, Rennert OM.  Copper and ceruloplasmin activity in human amniotic fluid.  Am J Obstet Gynecol.  138(3):257‑259, 1980.
  16. Chan WY, Ramadan TZ, Perlman M, McCaffree MA, Rennert OM. Copper and manganese in the mother and  in the neonate.  Nutr Rep Internat.  22(6):939‑948, 1980.
  17. Rennert OM, Chan WY, Griesmann GE.  Polyamine‑peptide conjugates:  Proposed functions.  Physiol Chem  Phys. 12(5):441‑­450, 1980.
  18. Chan WY, Rennert OM.  The role of copper in iron metabo­lism. Ann Clin Lab Sci.  10(4):338‑­344, 1980.
  19. Chan WY,  Rennert OM.  Cadmium nephropathy.  Ann Clin Lab Sci.  11(3):229‑238, 1981.
  20. Chan WY, Mosca P, Rennert OM.  Lithium nephrotoxicity: A review. Ann Clin Lab Sci. 11(4):343‑349, 1981.
  21. Perlman M, Chan WY, Ramadan TZ, Rennert OM.  Urinary polyamine in preterm infants.  Clin Chim Acta.   113:1‑6, 1981.
  22. Chan WY, Chung KW, Bates J, Blomberg LA, Rennert OM. Organ specific zinc deficiency in testicular feminization rats:  Hormone­‑me­tal interaction.  Biochem Biophys Res Comm. 102(2):630‑­635, 1981.
  23. Seiler N, Knodgen B, Gittos MW, Chan WY, Griesmann GE, Rennert OM.  On the formation of amino    acids deriving from spermi­dine and spermine.  Biochem J. 200(1):123‑132, 1981.
  24. Chan WY, Bates J, Rennert OM.  Comparative studies of manganese binding in human breast milk, bovine  milk and infant formula.  J Nutr.  112(4):642‑651, 1982.
  25. Chan WY, Rennert OM.  Prenatal and postnatal diagnosis of diseases of copper metabolism. Ann Clin Lab Sci.  12(5):372‑380, 1982.
  26. Griesmann GE, Chan WY, Rennert OM.  Determination of gamma‑aminobutyric acid by reverse‑­phase HPLC and pre‑column labeling for fluorescence detection.  J Chromat.  230:121‑124, 1982.
  27. Perlman M, Chan WY, Ramadan TZ, McCaffree MA, Rennert OM.  Serum copper and ceruloplas­min in preterm infants:  Prospective study.  J Am Coll Nutr.  1:155‑163, 1982.
  28. Liu HC, Chan WY, Rennert OM.  Histochemical studies of fibroblasts from patients with Menkes' Kinky Hair Disease and Wilson's Disease.  Histochem J.  14:781‑789, 1982.
  29. Chan WY, Chung KW, Bates JM Jr, LeBlanc M, Tease LA, Griesmann GE, Rennert OM. Zinc metabolism in testicular feminization and cryptorchid testes in rats.  Life Sci. 32(11):1279‑1284, 1983.
  30. Chung KW, Chan WY, Dressler JB, Allison JE, Rennert OM. Androgen receptors in the brain of neonatal normal male and androgen insensitive rats.  Biochem Biophys Res Comm. 111(2):717‑722, 1983.
  31. Rixon MW, Chan WY, Davie EW, Chung DW.  Characterization of a cDNA coding for a‑chain of human fibrinogen. Biochemistry.  22(13): 3237‑3244, 1983.
  32. Chung DW, Chan WY, Davie EW.  Characterization of a cDNA coding for the g‑chain of human fibrinogen.  Biochemistry.  22(13): 3250‑3256, 1983.
  33. Fan MZ, Chan WY, Griesmann G, Rennert OM.  Polyamine metabolism in McCoy cells:  I. Comparative studies of extracellular polyamine conjugated proteins of human fibroblast and McCoy cultures. Physiol Chem Phys. 15(1):57‑68, 1983.
  34. Fan MZ, Chan WY, Rennert OM.  Polyamine metabolism in McCoy cells:  II. Cellular origin of excreted polyamine conjugated proteins.  Physiol Chem Phys.  15(1):69‑80, 1983.
  35. Fan MZ, Chan WY, Griesmann G, Rennert OM.  Polyamine metabolism in McCoy cells: III. Comparative studies of metabolic fate of exogenous putrescine in human fibroblast cultures and McCoy  cultures.  Physiol Chem Phys.  15(1):81‑86, 1983.
  36. Wang CS, Chan WY, Kloer H‑U.  Comparative studies on the chemical and immunochemical properties of human milk, human pancreatic juice and bovine milk lactoferrin.  Comp Biochem Physiol. 78B(3):575­-580, 1984.
  37. Blackett PR, Lee DM, Donaldson DL, Fesmire JD, Chan WY, Holcombe JH, Rennert OM.  Studies of lipids, lipoproteins and apolipoproteins in Menkes Disease.  Pediat Res.  18(9):864‑870, 1984.
  38. Chan WY, Bates JM. Jr, Rennert OM, Mamood A, Torres‑Pinedo R.  Intestinal transport of manganese from human milk, bovine milk and infant formula in rats.  Life Sci.  35(24):2415‑2­419,1984.
  39. Raghib H, Chan WY, Rennert OM.  Effect of age, method of feeding and prior fasting on the absorption of milk manganese in suckling rats.  Nutr Rep Internat.  32(5):1201‑1210, 1985.
  40. Garnica AD, Chan WY, Rennert OM.  Trace metals in genetic disease.  Trace Metals Med. 2(2):47‑58, 1985.
  41. Chan WY, Rennert OM.  Genetic trace metal disturbances.  J Am Coll Nutr.  4(1):39‑48, 1985.
  42. Chung KW, Kim SY, Chan WY, Rennert OM.  Androgen receptors in prostate glands of zinc deficient rats. Life Sci.  38(1):351­356, 1986.
  43. Raghib MH, Chan WY, Rennert OM.  Comparative bioavailability of manganese from extrinsically labeled milk diets using suckling rats as a model.  Brit J Nutr.  55(1):49‑58, 1986.
  44. Chan WY, Bates JM Jr, Rennert OM, Chung KW.  Abnormal zinc metabolism in unilateral maldescended testes of a mutant rat strain.  Proc Soc Expt Biol Med.  182(4):549‑558, 1986.
  45. Raghib H, Chan WY, Rennert OM.  Comparative studies of selenium‑75 (Selenite and Selenomethionine) absorption from various milk diets in suckling rats. J Nutr.  116(8):1456‑1463, 1986.
  46. Chan PK, Chan WY, Yung BY‑M, Cook RG, Aldrich MB, Ku D, Goldknopf LL, Busch H. Amino acid  sequence of a specific antigenic peptide of protein B23.  J Biol Chem.  261(30):14335‑14341, 1986.
  47. Chan WY, Bates JM Jr, Rennert OM, Chung KW.  Absence of a 23kd protein in testes of testicular feminization rats.  Life Sci. 40(22):2169-2173, 1987.
  48. Raghib HM, Chan WY, Rennert OM. Absorption of milk manganese in suckling rats.  Nutr Rep Internat. 35(6):1111-1121, 1987.
  49. Chan WY, Tease LA, Borjigin J, Chan PK, Rennert OM, Srinivasan B, Shupert WL, Cook RG. Pregnancy-specific b1-glycoprotein mRNA is present in placental as well as non-placental tissues. Hum Reprod. 3(5):677-686, 1988.
  50. Chan WY, Tease LA, Bates JM Jr, Borjigin J, Shupert WL.  Pregnancy-specific b1-glycoprotein in rats: Tissue distribution of the mRNA and identification of testicular cDNA clones.   Hum Reprod. 3(5):687-692, 1988.
  51. Chan WY, Qiu WR.  Human Pregnancy-specific b1-glycoprotein is encoded by multiple genes localized on two chromosomes.  Am J Hum Genet. 43(2):152-159, 1988.
  52. Chan WY, Borjigin J, Zheng QX, Shupert WL. Characterization of cDNA encoding human pregnancy-specific b1-glycoprotein from placenta and extraplacental tissues and their comparison with carcinoembryonic antigen. DNA. 7(8):545-555, 1988.
  53. Chan WY, Liu QR, Borjigin J, Busch H, Rennert OM, Tease LA, Chan PK. Characterization of a cDNA encoding human nucleophosmin and studies of its function in normal and abnormal growth. Biochemistry.  28(3):1033-1039, 1989.
  54. Tease LA, Fazleabas AG, Chan WY. Expression of pregnancy-specific b1-glycoprotein in baboon placenta.  Biol Reprod. 41:1113-1121, 1989.
  55. Borjigin J, Tease LA, Barnes W, Chan WY.  Expression of pregnancy-specific b1-glycoprotein in human testis. Biochem Biophys Res Comm. 166(2):622-629, 1990.
  56. Ogilvie S, Shiverick KT, Larkin LH, Romrell LJ, Shupert WL, Chan WY. Pregnancy-specific b1-glycoprotein mRNA and immunoreactive-protein in the testis of rat.  Endocrinology. 126(1):292-298,1990.
  57. Zheng QX, Tease LA, Shupert WL, Chan WY. Characterization of cDNAs of the human pregnancy-specific b1-glycoprotein family - A new subfamily of the immunoglobulin gene superfamily. Biochemis­try. 29(11): 2845-2852, 1990.
  58. Jose P, Felder RA, Felder CC, Chan WY.  Molecular  biology of adrenergic and dopamine receptors and  the  study of developmental nephrology.  Pediat Nephrol. 4:679-685, 1990.
  59. Ho WKK, Liu SC, Shaw PC, Yeung HW, Ng TB, Chan WY. Cloning of the cDNA of a-momorcharin: A ribosome inactivating protein. Biochim Biophys Acta  1088:311-314, 1991.
  60. Chan WY,  Zheng QX, McMahon J, Tease LA. Characterization of new members of the pregnancy specific b1-glycoprotein family.  Mol Cell Biochem. 106:161-170, 1991.
  61. Richardson LL, Chan WY, Dym M. Localization of a "pregnancy-specific" b1-glycoprotein in the male    reproductive tract of the rat by in situ hybridization. Biol Reprod. 45: 704-710, 1991.
  62. Chan WY.  The pregnancy-specific b1-glycoprotein family. Adv Contr Deliv Syst.  7:21-52, 1991.
  63. Shupert WL, Chan WY. Pregnancy-specific b1-glycoprotein (PSG) in human intestine. Mol Cell Biochem. 120:159-170, 1993.
  64. Wu SM, Bazar L, Cohn M J, Cahill R, Chan WY.  Expression of pregnancy-specific b1-glycoproteins in   hematopoietic cells.  Mol Cell Biochem. 122:147-158, 1993.
  65. Ida H, Rennert OM, Eto Y, Chan WY. Identification of a cDNA encoding human acid sphingomyelinase with a new mutation that renders the enzyme inactive.  J Biochem. 114:15-20, 1993.
  66. Chen H, Chan WY, Chen C-L, Mansfield, BC, Chou JY. The carboxyl-terminal domain of the human pregnancy specific glycoprotein specifies intracellular retention and stability. J Biol Chem. 268(29):22­066-22075, 1993.
  67. Pan C-J, Chamberlin ME, Wu SM, Chan WY, Chou JY. Pregnancy-specific b1-glycoprotein genes expression and their induction by 5-bromo-2'-deoxy-uridine. Biochemistry. 33(23):7260-7266, 1994.
  68. Garnica AD, Chan WY, Rennert OM. Copper-histidine treatment of Menkes' disease. J Pediat. 125(2):336-338, 1994.
  69. Rennert OM, Chan WY, Garnica AD.  Menkes kinky hair disease - A glimpse from the past into the future. Menkes disease: The study of copper metabolism.  Internat Pediat. 9(Supp. 2):69-73, 1994.
  70. Laue L, Chan WY, Hsueh AJW, Kudo M, Hsu SY, Wu SM, Blomberg LA, Cutler GB Jr. Genetic heterogeneity of constitutively activating mutations of the luteinizing hormone receptor in familial male-  limited precocious puberty. Proc Natl Acad Sci, USA. 92(6):1906-1910, 1995.
  71. Laue L, Wu SM, Kudo M., Hsueh AJW, Griffin JE, Wilson JD, Grant DB, Brain C, Berry EC, Cutler GB Jr, Chan WY. A nonsense mutation of the human luteinizing hormone receptor gene in Leydig cell hypoplasia. Hum Mol Genet. 4(8):1429-1433, 1995.
  72. Garnica AD, Chan WY. The role of the placenta in fetal nutrition and growth.  J Am Coll Nutr. 15(3):206 -222, 1996.
  73. Bano M, Prasad S, Dickson RB, Chan WY. Detection of pregnancy-specific b1-glycoprotein in human milk. Breast. 5:61-66, 1996.
  74. Laue LL, Wu SM, Kudo M, Bourdony CJ, Cutler GB Jr, Hsueh AJW, Chan WY. Compound heterozygous mutations of the luteinizing hormone receptor gene in Leydig Cell Hypoplasia. Mol Endocrinol. 10(8): 987-997, 1996.
  75. Laue L, Wu SM, Kudo M, Hsueh AJW, Cutler GB Jr, Jelly DH, Diamond FB, Chan WY. Heterogeneity of activating mutations of the human luteinizing hormone receptor in male-limited precocious puberty. Biochem Mol Med. 58:192-198, 1996.
  76. Wu SM, Blomberg LA, Chan WY. Recovery of PCR products from polyacrylamide gel for sequencing. BioTechniques. 21(3):358-362, 1996.
  77. Garnica AD, Chan WY. Placenta and growth factors in fetal growth and nutrition. Nutrition  13(4):384-385, 1997.
  78. Stratakis CA, Lin J-P, Pras E, Rennert OM, Bourdony CJ, Chan WY. Allgrove (Triple-A) syndrome in Puerto Rican kindreds maps to chromosome 12 (12q13). Proc Assoc Am Physicians. 109(5):478-482,1997.
  79. Wu SM, Jose M, Hallermeier K, Rennert OM, Chan WY.  Polymorphisms in the coding exons of the human luteinizing hormone receptor. Hum Mut. Mutation in Brief #124, On-line,1997.11(4): 333-334, 1998.
  80. Blomberg LA, Wu SM, Dirami G, Dym M, Chou JY, Chan WY. Characterization and cellular localization of pregnancy-specific b1-glycoproteins in rat testis. Mol Cell Biochem. 177:229-237, 1997.
  81. Chan WY, Cutler GB Jr. Molecular aspects of precocious puberty. Adv Mol Cell Endocrinol 2:121-141, 1998.
  82. Blomberg LL, Cohn MJ, Cahill RA, Chan WY. Effect of human pregnancy-specific b1 glycoprotein on blood cell regeneration after bone marrow transplant. Proc Soc Expt Biol Med. 217:212-218, 1998.
  83. Chan WY, Cutler GB Jr. Mutations of gonadotrophin receptors leading to loss or gain of function. Top  Endocrinol. 8:9-12, 1998.
  84. Chan WY. Molecular genetic, biochemical, and clinical implications of gonadotropin receptor mutations. Mol Genet Metab. 63(2):75-84, 1998.
  85. Martin MM, Wu SM, Martin ALA, Rennert OM, Chan WY. Testicular seminoma in a patient with a constitutively activating mutation of the luteinizing hormone/chorionic gonadotropin receptor. Euro J Endocrinol. 139:101-106, 1998.
  86. Wu SM, Stratakis CA, Chan CHY, Hallermeier K, Bourdony CJ, Chan WY. Genetic heterogeneity of ACTH resistance syndromes: A novel mutation of the ACTH receptor gene in hereditary glucocorticoid deficiency. Mol Gen Metab. 64:256-265, 1998.
  87. Wu SM, Hallermeier MK, Laue L, Brain C, Berry EC, Grant DB, Griffin JE, Wilson JD, Cutler GB Jr, Chan WY. Inactivation of the luteinizing hormone/chorionic gonadotro­pin receptor by insertional mutation in Leydig cell hypoplasia. Mol Endocrinol. 12(11):1651-1660, 1998.
  88. Wu SM, Arnold LL, Rone J, Trivedi M, Chan WY.  Effect of pregnancy-specific b1-glycoprotein on the preimplantation embryo. Proc Soc Expt Biol Med. 220:169-177,1999.
  89. Wu SM, Leschek EW, Brain C, Chan WY. A novel mutation of the luteinizing hormone receptor in a patient with familial male-limited precocious puberty – effect of the size of a critical amino acid on receptor activity. Mol Genet Metab. 66:68-73 1999 (Journal Cover).
  90. Arnold LL, Doherty TM, Flor WA, Simon JA, Chou JY, Chan WY, Mansfield BC.  Pregnancy-specific glycoprotein gene expression in recurrent aborters: A potential correlation to interleukin-10 expression. Amer J Reprod Immunol. 41:174-182, 1999.
  91. Wu SM, Chan WY. Male pseudohermaphroditism due to inactivating luteinizing hormone receptor mutations. Arch Med Res. 30(6):495-500, 1999.
  92. Wu SM, Leschek EW, Rennert OM, Chan WY. Luteinizing hormone receptor mutations in disorders of sexual development and cancer. Frontiers Biosci. 5:D342-352, 2000.
  93. Wu SM, Leschek EW, Rennert OM, Chan WY. Luteinizing hormone receptor mutations in sexual development and cancer. J Pediat Path Mol Med. 19(1):21-40, 2000.
  94. Massaro GD, Massaro D, Chan WY, Clerch LB, Ghyselinck N, Chambon P, Chandraratna RAS. Signalling via retinoic acid receptor b mediates endogenous inhibition of the perinatal formation of pulmonary alveoli. Physiol Genomics. 4(1):51-57, 2000.
  95. Leschek EW, Chan WY, Diamond D, Laefer M, Jones J, Barnes KM, Cutler GB Jr. Nodular Leydig Cell           Hyperplasia in a boy with Familial Male-Limited Precocious Puberty (FMPP).  J Pediatr. 138(6):949-   951, 2001.
  96. Sandrini F, Farmakidis C, Kirschner LS, Wu SM, Tullio-Pelet A, Lyonnet S, Metzger DL, Bourdony CJ, Hochberg Z, Chan WY, Stratakis CA. Spectrum of mutations of the AAAS gene and genotype-phenotype correlation in patients with isolated resistance to corticotropin or Allgrove syndrome. J Clin Endocrinol Metab. 86: 5433-5437, 2001.
  97. Chan WY, Rennert OM. Molecular aspects of sexual differentiation. Curr Mol Med. 2:25-37, 2002.
  98. Bastain TM, Lewczyk CM, Sharp WS, James RS, Long RT, Eagen PB, Ebens CL, Meck JM, Chan WY,     Sidransky ER, Rapoport JL, Castellanos FX. Cytogenetic abnormalities in Attention- Deficit/ Hyperactivity Disorder. J Am Acad Child Adolesc Psychiatry. 41(7):1-5, 2002.
  99. Blomberg LA, Chan WY, Clerch L, Massaro G, Massaro D. Molecular cloning and characterization of         two genes up-regulated early in lung development. Biochim Biophys Acta, 1574(3):391-398, 2002.  
  100. Pang ALY, Taylor HC, Johnson W, Alexander S, Chen Y, Su YA, Li X, Ravindranath N, Dym M, Rennert OM, Chan WY. Identification of differentially expressed genes in spermatogenesis in the mouse. J Androl. 24(6):899-911, 2003.   
  101. Dogulu CF, Kansu T, Leung MYK, Baxendale V, Wu SM, Ozguc M, Chan WY, Rennert OM. Evidence     for genetic susceptibility to thrombosis in Pseudotumor Cerebri. Thromb Res, 111(6):389-395, 2003.
  102. Leung MLY, Al-Muslim O, Wu SM, Azizs A, Inam S, Awadh M, Rennert OM, Chan WY.  A novel  missense homozygous inactivating mutation in the fourth transmembrane helix of the luteinizing hormone receptor in Leydig Cell Hypoplasia. Amer J Med Genet, 130A:146-153, 2004.
  103. Wu SM, Baxendale V, Chen Y, Li X, ALY Pang, Stitely T, Munson PJ, Leung MYK, Ravindranath N, Dym M, Rennert OM, Chan WY.  Analysis of mouse germ cell transcriptome at different stages of spermatogenesis: Biological significance. Genomics, 84(6):971-981, 2004 (Journal Cover).
  104. Salameh W, Shoucair M, Guo TB, Zahed L, Wu SM, Rennert, O.M., and Chan WY.  Leydig cell hypoplasia due to inactivation of luteinizing hormone receptor by a novel homozygous nonsense truncation mutation in the seventh transmembrane domain.  Mol Cell Endocrinol. 229:57-64, 2004.
  105. Ohta S, Lai EW, Pang ALY, Brouwers FM, Chan WY,  Eisenhofer G, de Krijger R,  Ksinantova L, Blazicek P, Breza J, Kvetnansky R, Wesley RA, Pacak K. Down-regulation of metastasis suppressor gene in malignant pheochromocytoma. Internat J Cancer, 114:139-143, 2005.
  106. Ifon ET, Pang ALY, Johnson W, Cashman K, Zimmerman S, Muralidhar S, Chan WY, Casey J, Rosenthal LJ. U94 alters FN1 and ANGPTL4 gene expression and inhibits tumorigenesis of prostate cancer cell line PC3. Cancer Cell Internat, June 22, 5:19, 2005.
  107. Chan WY. Disorders of sexual development caused by luteinizing hormone receptors. Beijing Da Xue Xue Bao, 37(1):32-38, 2005.
  108. Liu Y, Yao ZX, Bendavid C, Borgmeyer C, Han Z, Cavalli LR, Chan WY, Folmer J, Zirkin, BR, Haddad BR, Gallicano I, and Papadopoulos V. Haploinsufficiency of cytochrome P450 17-hydroxylase/17,20 lyase (CYP17) causes infertility in male mice. Mol Endocrinol, 19(9):2380-2389, 2005.
  109. Nalbandian A, Pang ALY, Rennert OM, Chan WY, Ravindranath N, Djakiew D. A novel function of   differentiation revealed by cDNA microarray profiling of p75NTR-regulated gene expression. Differentiation. 73:385-396, 2005.
  110. Chan WY, Lee TL, Wu SM, Ruszczyk, L, Alba  D, Baxendale V, Rennert OM. Transcriptome analyses of male germ cells with SAGE. Mol. Cell. Endocrinol. 250:8-19, 2006.
  111. Hovrath A, Mathyakina L, Vong Q, Baxendale V, Pang ALY, Chan WY, Stratakis C. Serial analysis of  gene expression (SAGE) of the human adrenal gland: normal tissue and adrenocortical hyperplasia      caused by a germline PRKAR1A mutation. J. Clin. Endocriol. Metab. 91:584-596, 2006.
  112. Pang ALY, Johnson W, Dym M, Rennert OM, Chan WY. Expression profiling of purified male germ cells: stage specific expression patterns related to meiosis and post-meiotic development. Physiol Genomics, 24:75-85, 2006.
  113. Chan WY, Wu SM, Ruszczyk L, Law E, Lee TL, Baxendale V, Rennert OM. The complexity of antisense transcription revealed by the study of developing male germ cells. Genomics, 87:681-692, 2006.
  114. Lee TL, Alba D, Wu SM, Baxendale V, Rennert OM, Chan WY. Application of transcriptional network analyses in mouse germ-cell transcriptomes. Genomics, 88:18-33, 2006 (Journal Cover).
  115. Jeha GS, Lowenthal ED, Chan WY, Wu SM, Karaviti LP. Variable presentation of precocious puberty associated with the D564G mutation of the LHCGR gene in children with testotoxicosis. J Pediatr, 149(2):271-274, 2006.
  116. He Z, Chan WY, Dym M. Microarray technology offers a novel tool for the diagnosis of and    identification of therapeutic targets for male infertility. Reproduction, 132:11-19, 2006.
  117. Vong QP, Li YM. Lau CYF, Dym M, Rennert OM, Chan WY. Structureal characterization and expression studies of Dby and its homologs in the mouse. J Androl, 27(5):653-661, 2006.
  118. Leung MYK, Steinbach P, Bear D, Baxendale V, PY Fechner, Rennert OM, Chan WY. Biological effect of a novel mutation in the third leucine-rich repeat of human luteinizing hormone receptor. Mol Endocrinol, 20(10): 2493-2503, 2006.
  119. Oram SW, Liu XX, Lee TL, Chan WY, Lau YFC. TSPY potentiates cell proliferation and tumorigenesis by accelerating cell cycle progression in HeLa and NIH3T3 cells. BMC Cancer, 6:154, 2006 (09 June, 2006).
  120. Li YM, Tabatabai ZL, Lee TL, Hatakeyama S, Ohyama C, Chan WY, Looijenga LHJ, Lau YFC. The Y- encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ  cell tumors. Human Pathol, 38:1470-1481, 2007.
  121. Meng XL, Rennert OM, Chan WY. Human chorionic gonadotropin induced neuronal differentiation of PC12 cells through activation of stably expressed lutropin/choriogonadotropin  receptor. Endocrinology, 148(12):5865-5873, Dec 2007; Epub Aug 2007.
  122. Ohta S, Lai EW, Morris JC, Pang ALY, Watanabe M, Yazawa H, Zhang, R, Green JE, Chan WY, Sirajuddin P, Taniguchi S, Powers JF, Tischler AS, Pacak K. Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells. Mol  Carcinog, 47(4):245-251, 2008.  On-line Oct 23, 2007.
  123. Cheung HH, Chan WY, Lee TL. Stripping protocols for Affymetrix tiling Gene Chips. Nat Protocols, 2008, doi: 10.1038/nprot.2008.240, 2008. (IF:11.743, 5-yr IF, 3/75, Biochem Res Methods, 2012)
  124. Lee TL, Cheung AHH, Davis AJ, Rennert OM, Chan WY. The paradox of DNA methylation in transcriptional control, PLoS Biol, 6(3), 2008, March 21. (IF: 13.447, 5-yr IF, 10/290 Biochem & Mol Biol, 2012)
  125. Lee TL, Cheung HH, Claus J, Sastry C, Singh S, Vu L, Rennert OM, Chan WY. GermSAGE: A comprehensive SAGE database for transcript discovery on male germ cell development. Nucl Acid Res, 2009 Jan;37(Database issue):D891-897. Epub 2008 Oct 2. (IF:8.055, 5-yr IF, 27/290, Biochem &  Mol Biol, 2012)
  126. Kokkinaki M, Lee TL, He Zuping, Jang J, Golestaneh N, Hofmann MC, Chan WY, Dym M. The molecular signature of spermatogonial stem cells in the 6-day-old mouse testis. Biol Reprod, 80: 707-  717, 2009, 2008 Dec 23. [Epub ahead of print]. . (IF: 4.135, 5-yr IF,  5/28 Reproductive Biology 2012) 
  127. Brown JD, Dutta S, Bharti K, Bonner R, Munson PJ|, Dawid IB, Akhtar AL, Onojafe IF, Alur RP, Gross JM, Hejtmancik JF, Jiao X, Chan WY, Brooks BP. Expression profiling during ocular   development identifies two Nlz genes with a critical role in optic fissure closure. Proc Natl Acad Sci,  USA, 106(5):1462-1467, 2009; Epub 2009 Jan 26. (IF: 10.583, 5-yr IF, 5/56, Multidisciplinary Science, 2012)
  128. Lee TL, Pang ALY, Rennert OM, Chan WY. Genomic landscape of developing male germ cells. Birth Defect Res (Part C), 87(1):43-63, 2009. (2012 IF: 4.442)
  129. Pang ALY, Peacock S, Johnson W, Bear DH, Rennert OM, Chan WY.  Cloning, Characterization and  expression analysis of a novel acetyltransferase retrogene Ard1b in the mouse, Biol Reprod, 81(2): 302 –309 (2009). Epub: February 25, 2009 DOI:10.1095/biolreprod.108.073221. (IF: 4.135, 5-yr IF,5/28 Reproductive Biology 2012)
  130. Lee TL, Li YM, Alba D, Vong QP, Wu SM, Baxendale V, Rennert OM, Lau YFC, Chan WY.Developmental staging of male murine embryonic gonads by transcriptome analyses. J Genet Genomic, 36:215-227, 2009. (IF: 1.874, 5-yr IF, 105/161, Genetics & Heredity, 2012)
  131. Cheung HH, Lee TL, Rennert, O.M., and Chan WY. DNA methylation and cancer genome. Birth Defect Res (Part C), 87(4):335-350, 2009. (2012 IF: 4.42)
  132. Lee TL, Li Y, Cheung HH, Claus J, Singh S, Sastry C, Rennert OM, Lau YFC, Chan WY. GonadSAGE: a comprehensive SAGE database for transcript discovery on male embryonic gonad development. Bioinformatics, 26(4):585-586, 2010. Epub 2009 Dec 21. (IF: 6.911, 5-yr IF, 7/75 Biochem Res Methods, 2012)
  133. Chan WY, Lam STS, Wu BL.  An everlasting role of genetics and genomics in public health: a  meeting report of ACGA-HKSMG International Conference on Genetic and Genomic Medicine. J Genet Genomics, 36:189-190, 2009. (IF: 1.874, 5-yr IF, 105/161, Genetics & Heredity, 2012)
  134. Lee TL, Chan WY, Rennert OM.   Assessing the safety of nanomaterials by genomic approach could be another alternative. ACS Nano, 3(12):3830, 2009.  (IF: 12.524, 5-yr IF, 5/69, Nanoscience & Nanotechnology, 2012)
  135. Cheung HH, Lee TL, Davis AJ, Taft DH, Rennert OM, Chan WY. Genome-wide DNA methylation profiling reveals novel epigenetically regulated genes and non-coding RNAs in human testicular cancer. Brit J Cancer, 102(2):419-427, 2010.  Epub 2010 Jan 5.(IF: 4.206, 5-yr IF, 35/197, Oncology, 2014)
  136. Kokkinaki M, Lee TL, He Z, Jiang J, Golestaneh N, Hofmann MC, Chan WY, Dym M. Age affects gene expression in mouse spermatogonial stem/progenitor cells. Reproduction, 139: 1011-1020, 2010. (IF: 3.512, 5-yr IF, 6/28 Reproductive Biology, 2012)
  137. Nagrani SR, Levens ED, Baxendale V, Boucheron C, Chan WY, Rennert, OM. Methylation patterns of Brahma during spermatogenesis and oogenesis: Potential implications. Fertil Steril, 95(1):382-384,  2011. (IF: 3.96, 5-yr IF, 4/78, Obstet & Gynecol, 2012)
  138. Cheung H, Davis, AJ, Lee TL, Pang AL, Nagrani S, Rennert OM, Chan WY. Methylation of an intronic region regulates testicular cancer invasiveness via miR-199a.  Oncogene, 30(31):3405-3415, doi: 10.1038/onc.2011 (IF: 7.18, 5-yr IF, 19/197, Oncology, 31/290, Biochem & Mol Biol, 2012)
  139. Lambertini L, Lee TL, Chan WY, Lee MJ, Diplas A, Wetmur J, Chen J. Differential methylation of   imprinted genes in growth-restricted placentas.  Reprod Sci, 18(11):1111-1117, 2011,    PMID:21693779. (IF: 2.320, 5-yr IF, 25/78 Obstet & Gynecol, 2012)
  140. Pang AL, Clark J, Chan WY, Rennert OM. Expression of human NAA11 (ARD1B) gene is tissue- specific and is regulated by DNA methylation.  Epigenetics, 6(11):1-9, 2011. PMID:22048246. (IF:  4.881, 5-yr IF, 57/290 Biochem & Mol Biol, 2012)
  141. Lee TL, Raitano JM, Rennert OM, Chan SW, Chan WY.  Accessing the genomic effects of naked nanoceria in murine neuronal cells. Nanomed, 8(5):599-608, 2012, [Epub 2011 Sept 1], PMID:  21889474 (IF: 6.236, 5-yr IF, 16/69, Nanoscience & Nanotechnology, 2012)
  142. Cheung HH, Lee TL, Rennert OM, and Chan WY. Methylation profiling using Methylated DNA Immunoprecipitation and tiling array hybridization. Meth Mol Biol,825:115-126, 2012, PMID:22144241
  143. Lee TL, Rennert OM, Chan WY. Revealing the transcriptome landscape of mouse spermatogonial cells by tiling microarray. Meth Mol Biol, 825:75-92, 2012, PMID:22144238
  144. Gu S, Chan WY. Flexible and versatile as a chameleon - sophisticated functions of microRNA-199a,          Int. J. Mol. Sci., 13(7):8449-8466; 2012. doi:10.3390/ijms13078449. (IF: 2.464)
  145. Boucheron Boucheron-Houston C, Canterel-Thouennon L, Lee TL, Baxendale V, Nagrani S, Chan      WY, Rennert OM.  Long-term vitamin-A-deficiency induces alteration of adult mouse spermatogenesis and spermatogonial differentiation: direct effect on spermatogonial gene expression and indirect effects via somatic cells. J Nutr Biochem  2013 Jun;24(6):1123-1135, 2013.doi: 10.1016/j.jnutbio.2012.08.013. Epub 2012 Dec 17. PMID:23253600.
  146. Cheung DWS, Koon CM, Wat E, Ko CH, Chan JYW, Yew DTW, Leung PC, Chan WY, Lau CBS, Fung KP. A herbal formula containing roots of Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) inhibits inflammatory mediators in LPS-stimulated RAW 264.7 macrophages through inhibition of nuclear factor κB (NFκB) pathway. J Ethnopharmacol.  2013 Feb 13;145(3):776-783, 2013. doi: 10.1016/j.jep.2012.12.011. Epub 2012 Dec 20. (IF: 3.322, 5-yr IF, 3/22 Integrative & Complementary Medicine, 2012)
  147. Huen NY, Pang ALY, Lee TL, Vergati M, Jochems C, Tucker J, Intrivici C, Cereda V, Chan WY,         Rennert OM, Madan R, Gulley J, Schlom J, Tsang KY. Up-regulation of proliferative and migratory  genes in regulatory T cells form patients with  metastatic castration-resistant prostate cancer. Internat J Cancer, 2013 Jul 15;133(2):373-382, 2013.
  148. Kaipparettu BA, Ma Y, Lee TL, Zhang Y, Creighton C, Chan WY, Wong LJ. Cross talk from non   cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic    pathways. PLoS One, 2013 May 9;8(5):e61747,
  149. Tsang WH, Chen X, Hu JB, Wang C, Liu PC, Lu G, Zhao H, Poon WS, Chan WY, Feng B. Lif-dependent primitive neural stem cells derived from mouse ES cells represent a reversible stage of  neural commitment. Stem Cell Res, 2013 Nov;11(3):1091-1102, 2013. doi: 10.1016/j.scr.2013.07.007.    Epub 2013 Aug 2. PMID:23973799. (IF: 4.76, 5-yr IF, 58/185 Cell Biol, 2012)
  150. Cheung HH, Claus J, Singh S, Sastry C, Rennert OM, Chan WY, Lee TL. Mapping genomic features             of tiling microarray data by TileMapper. Meth Mol Biol. 1067:225-233, 2013. doi: 10.1007/978-1- 62703-607-8_14. PMID:23975795
  151. Chen BF, Gu S, Suen YK, Li L, Chan WY. MicroRNA-199a-3p, DNMT3A and aberrant DNA methylation in testicular cancer. Epigenetics, 9(1):1-8, 2014; Epub 2013 Aug 19.
  152. Koon CM, Ko CH, Sun XX, Hoi WH, Tam JCW, Cheung DWS, Cheng WKF, Pang SY, Lo WM, Chook PC, Lau CBS, Chan WY, Leung PC, Kwok T, Fung KP. Gene expression profiling on the  molecular action of Danshen-Gegen formula in a randomized placebo controlled trial of postmenopausal women with hypercholesterolemia. Evid-Based Comp Alternat Med. Vol 2013, Article ID:703705, 14 pages. doi: 10.1155/2013/703705. Epub 2013 Sep 23. PMID: 24174980. (IF: 2.14, 5-yr IF, 8/22 2012)
  153. Tsang WP, Shu Y, Kwok PL, Zhang F, Lee KKH, Tang MK, Li G, Chan KM, Chan WY, Wan C. CD146+ human umbilical cord perivascular cells maintain stemness under hypoxia and as a cell       source   for skeletal regeneration. PLoS One, 2013 Oct 18;8(10):e76153, 2013. doi: 10.1371/journal.pone.0076153. PMID:24204598. (IF: 4.244, 5-yr IF, 7/56 Multidisciplinary Science, 2012)
  154. Gu S, Cheung HH, Lee TL, Lu G, Poon WS, Chan WY. Molecular mechanisms of regulation and action of microRNA-199a in testicular germ cell tumor and glioblastomas. PLoS One,2013 Dec31;8(12):e83980, 2013. doi: 10.1371/journal.pone.0083980. (IF: 4.244, 5-yr IF, 7/56 Multidisciplinary Science, 2012)
  155. Ko CH, Yi S, Ozaki R, Cochrane H, Chung H, Lau W, Koon CM, Hoi SW, Lo W, Cheng KF, Lau CB,  Chan WY, Leung PC, Chan JC. Healing effect of a two-herb recipe (NF3) on foot ulcers in   Chinese patients with diabetes: A randomized, double-blind, placebo-controlled study. J Diabetes.  2014 July; 6:323-324, 2014. doi: 10.1111/1753-0407.12117. Epub 2014 Feb 24.
  156. Chen B, Chan WY. The de novo DNA methyltransferase DNMT3A in development and cancer. Epigenetics, 9(5):669-677, 2014.  March 3, 2014 [Epub ahead of print], PMID:24589714 (2014 IF: 5.108, 57/290  Biochem & Mol Biol, 2012)
  157. Luk ACS, Chan WY, Rennert OM, Lee TL.  Long non-coding RNAs in spermatogenesis: insights from recent high-throughput transcriptome studies. Reproduction, 147:R131-R141, 2014. DOI: 10.1530/REP-13-0594. ISSN 1470–1626 (paper) 1741–7899 (online). (IF: 3.512, 5-yr IF, 12/41 Developmental Biology,  6/28 Reproductive Biology, 2012)
  158. Tam JCW, Ko CH, Lau KM, To MH, Kwok HF, Lau CP, Siu WS, Etienne-Selloum N, Chan WY,          Leung PC, Fung KP, Schini-Kerth VB, and Lau CBS. A Chinese 2-herb formula (NF3) promoted hindlimb ischemia-induced neovascularization and wound healing of diabetic rats. J Diabetes Complications. 2014 Jul-Aug; 28(4):436-447, 2014. doi:10.1016/j.jdiacomp.2014.03.004. Epub 2014    Mar 21.
  159. Tam J, Ko CH, Zhang C, Wang H Lau CP, Chan WY, Leung PC, Fung KP, Kung HF, Lau CBS. Comprehensive proteomic analysis of a Chinese 2-herb formula (Astragali Radix and Rehmanniae Radix) on mature endothelial cells. Proteomics, 2014 Sep; 14(17-18):2089-2103, 2014. doi: 10.1002/pmic. 201300547. Epub 2014 Aug 21. PMID: 25044676
  160. Zhang F, He Q, Tsang WP, Garvey WT, Chan WY, Clemens TL, Wan C. Insulin exerts direct, IGF-1    independent actions in growth plate chondrocytes. Bone Research. 2014, 2(2):14012.
  161. Chen BF, Suen YK, Gu S, Li L, Chan WY. A miR-199a/miR-214 self-regulatory network via PSMD10, TP53 and DNMT1 in testicular germ cell tumor. Scientific Reports, 2014 Sep 18;4:6413, 2014. doi: 10.1038/srep06413. PMID:25231260.
  162. Tam JC, Ko CH, Lau KM, To MH, Kwok HF, Siu WS, Lau CP, Chan WY, Leung PC, Fung KP, Lau CB. Enumeration and functional investigation of endothelial progenitor cells in neovascularization of diabetic foot ulcer rats with a Chinese 2-herb formula. J Diabetes. 2014 Oct 28. doi: 10.1111/1753-0407.12230. [Epub ahead of print] PMID:25350858.
  163. Li L, Zhang Y, Fan Y, Sun K, Su XW, Du ZF, Tsao SW, Loh KS, Sun H, ATC Chan, Lo YM, Chan WY, Chan FKL, Tao Q. Methylome study of nasopharyngeal carcinoma identifies disruption of key signaling pathways and methylated tumor suppressor genes. Epigenomics, 2014 Dec 5:1-19, 2014. [Epub ahead of print] PMID: 25479246.
  164. Li L, Chen BF, Chan WY. An Epigenetic Regulator: Methyl-CpG-Binding Domain Protein 1 (MBD1).  Internat J Mol Sci., 16: 5125-5140, 2015; doi:10.3390/ijms16035125
  165. Chen X, Gu S, Chen BF, Shen WL, Yin Z, Xu GW, Hu JJ, Zhu T, Li G, Ouyang HW, Wan C, Lee TL, Chan WY. Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway. Biomaterials, 53:239-250, 2015. doi: 10.1016/j.biomaterials.2015.02.071. Epub 2015 Mar 14
  166. Wu Y, Li Y, Zhang H, Huang Y, Zhao P, Tang Y, Qiu X, Ying Y, Li W, Ni S, Zheng M, Liu L, Xu Y,  Zhuang Q, Luo Z, Benda C, Song H, Liu B, Lai L, Liu X, Tse HF, Bao X, Chan WY, Esteban MA,  Qin B, and Pei D. Autophagy and mTORC1 regulate the Early Phase of Somatic Cell Reprogramming.  Nat Cell Biol, 2015 Jun;17(6):715-25. doi: 10.1038/ncb3172. Epub 2015 May 18. PMID:25985393.
  167.   Luk ACS, Gao H, Liao J, Li P, Edmunds S, Wang D, Rennert OM, Chan WY, Lee TL. GermlncRNA: a  unique catalog of long noncoding RNAs and associated regulations in male germ cell development. Database (Oxford). 2015 May 17;2015:bav044. doi: 10.1093/database/bav044. Print 2015.  PMID:25982314.
  168. Qian Y, Tu J, Tang NLS, Kong GWS, Chung JPW, Chan WY, Lee TL. Dynamic changes of DNA epigenetic marks in mouse oocytes during natural and accelerated aging. Internat J Biochem Cell Biol, 2015 May 14. pii: S1357-2725(15)00126-0. doi: 10.1016/j.biocel.2015.05.005. [Epub ahead of print] PMID:25982203.
  169. Tu J, Liao JJ, Luk ACS, Tang NLS, Chan WY, Lee TL. MicroRNAs mediated targeting on the Yin-yang dynamics of DNA methylation in disease and development. Internat J Biochem Cell Biol, 2015 May 12. pii: S1357-2725(15)00123-5. doi: 10.1016/j.biocel.2015.05.002. [Epub ahead of print] PMID:25979370.
  170. Tu J, Ng SH, Luk ACS, Liao JJ, Jiang XH, Feng B, Mak KKL, Rennert O, Chan WY, Lee TL. MicroRNA-29b/Tet1 regulatory axis epigenetically modulates mesendoderm differentiation in mouse embryonic stem cells. Nucl Acid Res, 2015 June 30, doi: 10.1093/nar/gkv653.
  171. Chen ZJ, Zhao S, Tian Y,  Gao X, Zhang X, Liu H, You L, Cao Y, Su S, Chan WY, Sun Y, Zhao H. Family-based analysis of eight new susceptibility loci from genome-wide association study for polycystic ovary syndrome. Scientific Reports, 2015 Jul 29;5:12619. doi: 10.1038/srep12619.
  172. Cheung RCF, Ng TB, Wong JH, Chan WY. Chitosan: An update on potential biomedical and pharmaceutical applications. Marine Drugs. 13:5156-5186, 2015; doi:10.3390/md13085156.
  173. Culty M, Liu Y, Manku G, Chan WY, Papadopoulos V. Expression of steroidogenesis-related genes in murine male germ cells. Steroids, 2015 Aug 21. pii: S0039-128X(15)00225-1. doi: 10.1016/j.steroids.2015.08.011. [Epub ahead of print] PMID:26302977
  174. Feng EF, Scheibye-Knudsen M, Jahn HJ, Li J, Ling L, Guo H, Zhu X, Preedy V, Lu H, Bohr VA, Chan WY, Liu Y, Ng TB. A research agenda for aging in China in the 21st century. Aging Res Rev, 2015, Aug 22. pii: S1568-1637(15)30016-7. doi: 10.1016/j.arr.2015.08.003. [Epub ahead of print]. PMID:26304837
  175. Ng TB, Cheung RCF, Wong JH, Chan WY. Proteins, peptides, polysaccharides and nucleotides with inhibitory activity on human immunodeficiency virus and its enzymes.  Appl Microbiol Biotechnol. 2015 Sep 28. [Epub ahead of print] PMID: 26411457.
  176. Akkouh O, Ng TB, Wong JH, Pan W, Cheung RCF, Ng CCW, Sha O, Shaw PC, Chan WY. Biological activities of ribosome inactivating proteins and their possible applications as antimicrobial, anticancer and anti-pest agents and in neuroscience research.  Appl Microbiol Biotechnol. 2015 Sep 22. [Epub ahead of print] PMID:26394859.
  177. Cheung HH, Pei DQ, Chan WY. Stem cell aging in adult Progeria. Cell Regeneration, 2015, 4:6 DOI 10.1186/s13619-015-0021-z [Epub] October 2015.
  178. Tam JCW, Ko CH, Koon CM, Lau CP, Leung PC, Fung KP, Chan WY, Lau CBS. Identification of target genes involved in wound healing angiogenesis of endothelial cells with the treatment of a Chinese 2-herb formula. PLoS One, 2015 (Accepted).

Manuscript Submitted

  1. Lee TL, Tu JJ, Ng SH, Luk ACS, Liao JJ, Feng B, Mak KKL, Chan WY. MicroRNA-29b contributes to mouse embryonic stem cells differentiation by suppressing 5-hydorxymethylcytosine level via Tet1/2.  Cell Research. 2013.
  2. Tsang WP, Cai W, Huang J, He Q, Zhang F, Chan WY, Shen Z, Wan C. Phytomolecule Icaritin enhances mouse embryonic stem cells self-renewal through promoting G1/S transition mediated by inhibition of Cdx2 and p130. Stem Cells. 2014.
  3. Pang ALY, Title AC, Lee TL, Chan WY, Rennert OM. Histone modification and transcription factor Sp1 are involved in the regulation of mouse Lin28a gene transcription. PLoS One, 2014.
  4. Li P, Gao H, Edmunds SC Luo R, Lam TW, Li Z, Tang NLS, Chan WY, Yue L, Lee TL. Practicing reproducible bioinformatics on NGS analyses with GigaGalaxy. Briefings Bioinformatics. 2014.
  5. Liu XZ, Campanac E, Cheung HH, Ziats MN, Canterel-Thouennon L, Raygada M, Baxendale V, Pang ALY, Yang L, Swedo S, Thurm A, Lee TL, Fung KP, Chan WY, Hoffman D, Rennert OM. Cellular and molecular phenotypes associated with idiopathic autism in iPSC-derived neurons. Molecular Psychiatry. 2015.
  6. Li Q, Hutchins AP, Chen Y, Li S, Zheng D, Shi X, Li Y, Chan W-Y, Pan G, Wei S, Shu X, Pei D. EMT-MET as a unified mechanism for reprogramming and differentiation Nature Cell Biology, 2015.
  7. Chan CLK, Chan WY, Cheng CHK, Xia P. What is missing in STD screening in Hong Kong? Sexually Transmitted Infections, BMJ, 2015.
  8. Zhao S, Xu H, Cui Y, Wang W, Qin Y, You L, Chan WY, Sun Y, Chen ZJ. No obvious effect of high androgen on metabolic actions of insulin in ovarian granulosa cells: lessons from in vitro studies. Molecular Cellular Endocrinology, 2015.
  9. Pan WL, Wang Y, Hao Y, Chan WC, Wong JH, Wan DCC, Chan WY, Ng TB. Enhanced CXCR4 expression potentiates the susceptibility of the pro-migratory signaling to human cationic peptide LL-37 in breast cancer cells. Nature Communications, 2015.
  10. Ng TB, Chan WY, Wong JH, Cheung RCF, Ng CCW, Ye X, Zhang KY. Mellitin and derivatives with anticancer, antimicrobial, antiarthritic, neuroprotective and hepatoprotective effects. Journal of Integrative Medicine, 2015.
  11. Ng TB, Cheung RCF, Wong JH, Chen F, Chan WY. Marine natural products with anti-inflammatory activity: a review.  Applied Microbiology Biotechnology, 2015.

 

 

Wai-Yee Chan

Professor and Director

 

 

  • School of Biomedical Sciences Faculty of Medicine The Chinese
    University of Hong Kong
  • COUNTRYHong Kong