Journal Publications

  1. Michniak, B.  Recent advances in antiperspirant research.  Cosmetic Technology (1980) 2, (11),34-39.
  2. Michniak, B.  Do we undervalue the importance of pharmacy management courses at the undergraduate level?  J. Instit. Pharm. Manag. Int. (1980) 2, (1), 12-13.
  3. Michniak, B. Studies on the mechanism of topical anhidrosis due to polyvalent cations. Inter. J. Cosm. Sci. (1981) 3, (1), 29-36. Paper received "1981 Best Publication Prize" from the Society of Cosmetic  Scientists.
  4. Michniak, B.  Perspiration, antiperspirants and deodorants.  Pharm. J. (1982) 228, 452-453.
  5. Michniak, B.  Pharmacy management courses in the United States:  a study.  J. Instit. Pharm. Manag. Int. (1982), 4, (3), 12-13.
  6. Michniak, B.  Advances in topical corticosteroid therapy.  Int. J. Cosm. Sci. (1983) 5, (6), 277-291.
  7. Michniak, B.  A new approach to assessing sweat production.  Int. J. Cosm. Sci. (1983), 5, (6), 267-275.
  8. Michniak-Mikolajczak, B.  Sweat production in the isolated rat eccrine sweat gland.  Brit. J. Derm. (1984), 111 (3), 309-314
  9. Michniak-Mikolajczak, B.  Investigation of the presence of intercellular canaliculi in human and rat eccrine sweat glands.  Patalogia Polska (in English) (1984) 35 (4) 517-522
  10. Michniak, B.  Investigation of sweat production in the isolated rat eccrine sweat gland.  Pat. Pol. (in English) (1984) 35 (2), 231-238
  11. Michniak-Mikolajczak, B.  Dermatological preparations: problems of efficacy.  College of Pharmacy Practice Corresp. J. (1984) 4, 9-13
  12. Michniak-Mikolajczak, B.  Skin:  Nature's barrier to topical preparations?  College of Pharmacy Practice Corresp. J. (1984), March (3), 20-21
  13. Michniak-Mikolajczak, B. Bodor, N.  A study of the penetration of five novel synthetic steroids through hairless mouse skin in vitro.  Int. J. Cosm. Sci. (1985) 7, 175-179
  14. Michniak-Mikolajczak, B. An in vitro investigation of the astringency property of certain anhidrotic solutions.  Polish J. Pharmac. Pharm. (in English) (1985) 37, 141-145.
  15. Michniak-Mikolajczak, B., Barry, B.W., Waller, I.L. A microbalance technique for measuring water vapour uptake and release by stratum corneum in vitro. Int. J. Pharm. (1986) 31, (3) 247- 260.
  16. Michniak, B.B., Chapman, J.M.  Comparison of percutaneous penetration in vitro using clofibric acid esters and amides as novel enhancers in two species:  mouse and guinea pig.  Int. J. Cosm. Sci. (1992), 14, 153-161.
  17. Michniak, B.B., Chapman, J.M., Seyda, K.L.  Facilitated transport of two model steroids by esters and amides of clofibric acid.  J. Pharm. Sci. (1993) 82, (2) 214-219.
  18. Michniak, B.B., Seyda, K.L.  A simple and specific high liquid chromatography method for the assay of a series of novel dermal penetration enhancers.  Int. J. Cosm. Sci. (1993) 15, 7-13.
  19. Michniak, B.B., Player, M.R., Chapman, J.M., Jr., Sowell, J.W., Sr.  In vitro evaluation of a series of Azone analogs as dermal penetration enhancers I.  Int. J. Pharm. (1993) 91, 85-93.
  20. Michniak, B.B., Player, M.R., Fuhrman, L.C., Christensen, C.A., Chapman, J.M., Jr., Sowell, J.W., Sr.  In vitro evaluation of a series of Azone analogs as dermal penetration enhancers II. (Thio)amides.  Int. J. Pharm. (1993) 94 203-210.
  21. Michniak, B., Chapman, J.  Transdermal delivery of indomethacin and levonorgestrel using clofibric acid amides as penetration enhancers.  Drug Delivery (1993) 1 (1) 35-41.
  22. Michniak, B.B., Player, M.R., Fuhrman, L.C., Christensen, C.A., Chapman, J.M., Jr., Sowell, J.W., Sr. In vitro evaluation of a series of Azone analogs as dermal penetration enhancers III. Acyclic amides.  Int. J. Pharm. (1994) 110, 231-239.
  23. Michniak, B.B., Player, M.R., Chapman, J.M., and Sowell, J.W.  Azone analogues as penetration enhancers:  effect of different vehicles on hydrocortisone acetate skin permeation and retention.   J. Controll. Rel. (1994) 32, 147-154.
  24. Michniak, B.B., Player, M.R., Godwin, D.A., Phillips, C.A., and Sowell, J.W., Sr.  In vitro evaluation of a series of Azone analogs as dermal penetration enhancers IV.  Amines.  Int. J. Pharm. (1995), 116, 201-209.
  25. Michniak, B.B., Player, M.R., Godwin, D.A., and Sowell, J.W., Sr. Investigation of enhancer- structure activity relationships in congeners of 2-(1-nonyl)-1,3-dioxolane.  Drug Delivery (1995) 2, 117-122.
  26. Phillips, C.A. and Michniak, B.B.  Topical application of Azone analogs to hairless mouse skin: a histopathological study.  Int. J. Pharm. (1995), 125, 63-71.
  27. Phillips, C.A. and Michniak, B.B.  Transdermal delivery of drugs with differing lipophilicities using Azone analogs as dermal penetration enhancers.  J. Pharm. Sci. (1995), 84 (12), 1427-1433.
  28. Michniak, B.  Beauty is only skin deep.  Cosmetic Horizons, Jan. (1995), pp. 2 and 4.
  29. Michniak, B.  Skin aging and preventive treatment.  Cosmetic Horizons, March (1995), pp. 2 and 4.
  30. Michniak, B.  Moisturizing and the skin.  Cosmetic Horizons, April (1995), pp. 2 and 4.
  31. Michniak, B., Player, M.R., and Sowell, Sr., J.W.  Synthesis of and in vitro transdermal penetration enhancing activity of lactam-N-acetic acid esters.  J. Pharm. Sci. (1996), 85 (2), 150- 154.
  32. Fincher, T.K., Yoo, S.D., Player, M.R., Sowell, Sr., J.W., and Michniak, B.B.  In vitro evaluation of a series of N-dodecanoyl-L-amino acid methyl esters as dermal penetration enhancers.  J. Pharm. Sci. (1996), 85 (9), 920-923.
  33. Fuhrman, Jr., L.C., Michniak, B.B., Behl, C.R., and Malick, A.W.  Effect of novel penetration enhancers on the transdermal delivery of hydrocortisone: an in vitro species comparison.  J. Controlled Release (1996) 45 (2), 197-204.
  34. Hunter, D.A., Yoo, S.D., Fox, J.L., and Michniak, B.B.  Stability of premixed albuterol solutions for nebulization.  Int. J. of Pharmaceutical Compounding (1998), 2 (5), 394-396.
  35. Godwin, D.A., Michniak, B.B., Player, M.R., and Sowell, Sr., J.W.  Transdermal and dermal enhancing activity of pyrrolidinones in hairless mouse skin.  Int. J. Pharm. (1997), 155(2), 241- 250.
  36. Godwin, D.A., Michniak, B.B., and Creek, K.  Evaluation of transdermal penetration enhancers using a novel skin alternative.  J. Pharm. Sci. (1997), 86 (9), 1001-1005.
  37. Michniak, B.B., Player, M.R., Godwin, D.A., Lockhart, C.C., and Sowell, Sr., J.W.  In vitro evaluation of a series of Azone analogues as dermal penetration enhancers.  V.  Miscellaneous compounds.  Int. J. Pharm. (1998), 161, 169-178.
  38. Godwin, D.A., Player, M.R., Sowell, Sr., J.W., and Michniak, B.B.  Investigation of novel urea compounds as transdermal penetration enhancers.  Int. J. Pharm. (1998) 167 (1-2), 165-175.
  39. Godwin, D.A. and Michniak, B.B.  Influence of drug lipophilicity on terpenes as transdermal penetration enhancers.  Drug Develop. and Industrial Pharmacy  (1999) 25 (8), 905-915.
  40. Strekowski, L., Henary, M., Kim, N., Michniak, B.  (4-Bromobenzoyl)-S,S,- dimethyliminosulfurane, a potent dermal penetration enhancer.  Bioorganic and Medicinal Chemistry Letters (1999), 9,1033-1034.
  41. Asbill, C.S., Kim, N., Creek, C.E., and Michniak, B.B.  Comparison of transdermal penetration through human bioengineered skin, human skin and hairless mouse skin.  18th Southern Biomedical Engineering Conference & 2nd International Conference on Ethical Issues in Biomedical Engineering, Clemson University, Clemson, SC.  May 20-23, 1999.  Critical Reviews in Biomedical Engineering (1999), 26,406-407.
  42. Al-Khalili, M., Kim, N., and Michniak, B.B.  Comparison between hairless mouse skin and hairless Peromyscus Maniculatus as in vitro skin models.  18th Southern Biomedical Engineering Conference & 2nd International Conference on Ethical Issues in Biomedical Engineering, Clemson University, Clemson, SC.  May 20-23, 1999.  Critical Reviews in Biomedical Engineering (1999), 26, 411-412.
  43. El-Kattan, A. and Michniak, B.B.  Effect of zinc sulfate formulations on the permeation of zinc in human cadaver skin.  18th Southern Biomedical Engineering Conference & 2nd International Conference on Ethical Issues in Biomedical Engineering, Clemson University, Clemson, SC. May 20-23, 1999.  Critical Reviews in Biomedical Engineering (1999), 26, 410-411.
  44. El-Kattan, A.F., Asbill, C.S., Michniak, B.B. The effect of terpene enhancer lipophilicity on the percutaneous permeation of hydrocortisone formulated in HPMC gel systems. International Journal of Pharmaceutics  (2000), 198 (2), 179-189.
  45. Kim, N., El-Khalili, M., Henary, M.M., Strekowski, L., Michniak, B. Percutaneous penetration enhancement activity of aromatic S,S- dimethyliminosulfuranes. International Journal of Pharmaceutics, 1999, 187, 219-229.
  46. Asbill, C.A., Kim, N., El-Kattan, A., Creek, K., Wertz, P., Michniak, B.B. Evaluation of a human bioengineered skin equivalent  for drug permeation studies. Pharmaceutical Research, 2000, 17 (9), 1092-1097.
  47. Asbill, C.S., El-Kattan, A.F., Michniak, B.B. Enhancement of transdermal drug delivery: Chemical and Physical approaches.  Critical Reviews in Therapeutic Drug Carrier Systems, (2000), 17 (6), 621-658.
  48. El-Kattan, A. and Michniak, B.B. Effect of formulation variables on the percutaneous permeation of ketoprofen from gel formulations. Drug Delivery, 2000, 7, 147-153.
  49. Holladay, J.W., Dewey, M.J., Michniak, B.B., Wiltshire, H., Halberg, D.L., Weigl, P., Liang, Z., Halifax, K., Lindup, W.E., Back, D.J. Elevated alpha-1-acid glycoprotein reduces the volume of distribution and systemic clearance of saquinavir. Drug Metabolism & Disposition, 2001, March, 29 (3), 299-303.
  50. Kim, N., El-Kattan, A., Asbill, C.S., Kennette, R.J., Sowell, J.W. Sr., Latour, R., Michniak, B.B. Evaluation of derivatives of 3-(2-oxo-1-pyrrolidine) hexahydro-1H-azepine-2-one as dermal penetration enhancers: side chain length variation and molecular modeling. Journal of Controlled Release, 2001, 73,183-196.
  51. El-Kattan, A.F., Asbill, C.S., Kim, N., Michniak, B.B. The effect of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities. International Journal of Pharmaceutics, 2001, 215, 229-240.
  52. Wang, Y., Fan, Q., Song, Y., Michniak, B. Effect of fatty acids and iontophoresis on the delivery of midodrine hydrochloride and structure of human skin.  Pharm. Research 2003, 20 (10), 1612- 1618.
  53. Al-Khalili, M., Meidan, V., Michniak, B. Iontophoretic transdermal delivery of buspirone hydrochloride in hairless mouse skin. AAPS Pharm. Sci., 2003,5 (2), no pages, article 14 at http://www.pharmsci.org.
  54. Meidan, V., Al-Khalili, M., Michniak, B.  Enhanced iontophoretic delivery of buspirone hydrochloride across human skin using chemical enhancers. Int. J. Pharm., 2003, 264,73-83.
  55. Bourke, S., Al-Khalili, M., Michniak, B., Kohn, J., Poole-Warren, L. Protein drug release from photocrosslinked poly(vinyl alcohol) hydrogels. AAPS PharmSci, 2003 ; 5 (4) Article 33
    (http://www.aapspharmsci.org) 11  pages.
  56. Djordevic, J., Michniak, B., Uhrich, K.E. Amphiphilic star-like macromolecules as novel carriers for topical delivery of non-steroidal anti-inflammatory drugs. AAPS PharmSci , 2003; 5 (4)  Article 26 (http://www.pharmsci.org). pp. 256-267.
  57. Meidan, V. M., Michniak, B.B.  Emerging Technologies in Transdermal Therapeutics. Amer. J. Ther. 2004, 11 (4), 312-6.
  58. Song, Y., Wang, Y., Thakur, R., Meidan, V.M., Michniak, B. Mucosal Drug delivery: Membranes, Mechanisms and Applications. Critical Reviews in Therapeutic Drug Carrier Systems, 2004, 21 (3), 195-256.
  59. Fan, Q., Sirkar, K.K., Wang,Y. and Michniak, B.B. In vitro delivery of doxycycline hydrochloride based on a porous membrane-based aqueous-organic partitioning system. Journal of Controlled Release, 2004, 98, 355-365.
  60. Wang, Y., Thakur, R., Fan, Q., Michniak, B.B. Transdermal iontophoresis: Combination strategies to improve transdermal iontophoretic drug delivery. European J. of Pharmaceutics & Biopharmaceutics (2005), 60, 179-191.
  61. Pugh, W.J., Wong, R., Falson, F., Michniak, B.B. Moss, G.P. Discriminant analysis as a toll to identify compounds with potential as transdermal enhancers. J. Pharm. Pharmacol., 2005, 57 (11), 1389-96.
  62. Song, Y., Xiao, C., Mendelsohn, R., Zheng, T., Strekowski, L., Michniak, B.B.  Investigation of iminosulfuranes as novel transdermal penetration enhancers: enhancement activity and cytotoxicity. Pharm. Research (2005), 22 (11), 1918-1925.
  63. Barrow, D.J., Chandrasekaran, S., Heerklotz, H.H., Henary, M.M., Michniak, B.B., Nguyen,
  64. P.M. Song, Y., Smith, J.C., Strekowski, L. Mechanistic studies on percutaneous penetration enhancement by N-(4-halobenzoyl)-S,S,-dimethyliminosulfuranes. Journal of Lipid Research (2005), 46, 2192-2201.

  65. Meidan, V., Bonner, M.C. and Michniak, B.B. Transfollicular drug delivery: is it a reality? Int.
  66. Journal of Pharmaceutics, (2005), 306, 1-14.

  67. Batheja, P., Thakur, R., Michniak, B. Transdermal Iontophoresis. Expert Opinion in Drug Delivery (2006), 3 (1), 127-138.
  68. Simon, L., Weltner, A.N., Wang, Y., Michniak, B.  A parametric study of iontophoretic transdermal drug delivery systems.  Journal of Membrane Sciences, (2006), 278,124-132.
  69. Wang,Y., Wang, Y., Yang, J., Pfeffer, R., Dave, R., Michniak, B.  The application of a supercritical antisolvent process for sustained drug delivery. Powder Technology (2006), 164, 94- 102.
  70. Goyal, A., Mandapuram, S., Michniak, B., Simon, L. Application of orthogonal collocation and regression techniques for recovering parameters of a two-pathway transdermal drug delivery model. Computers & Chemical Engineering (2007), 31, 107-120.
  71. Dayan, N., Batheja, P., Michniak, B. Physical characteristics and skin penetration of lecithin- oleic acid lamellar delivery system. Cosmetics & Toiletries (2007), 122 (9), 73-82.
  72. Thakur, R., Meidan, V., Michniak, B. Transdermal and buccal delivery of methylxanthines through human tissue in vitro. Drug Develop. & Ind. Pharmacy (2007), 33, 513-521.
  73. Pensack, R.D., Michniak, B.B., Moore, D., Mendelsohn, R. I.R. kinetic/structural studies of barrier reformation in intact stratum corneum following thermal perturbation. Applied Spectroscopy, (2006) 60 (12), 1399-1404.
  74. Sheihet, L., Chandra, P., Batheja, P., Devore, D., Kohn, J., Michniak, B. Tyrosine-derived nanospheres for enhanced topical skin penetration. Int. J. Pharmaceutics, (2008), 350, 312-319.
  75. Batheja, P., Kaushik, D., Hu, L., Michniak, B. Transdermal iontophoresis. Drug Delivery (2007), pp.46-48.
  76. Kaushik, D., Batheja, P., Kilfoyle, B., Rai, V., Michniak-Kohn, B. Percutaneous Penetration modifiers: enhancement vs. retardation. Expert Opinion on Drug Delivery, (2008), May 5 (5), 517-529.
  77. Thakur, R.A., Florek, C.A., Kohn, J., Michniak, B. Electrospun nanofibrous polymeric scaffold with targeted drug release profiles for potential application as wound dressing. International J. of Pharmaceutics, (2008), 364, 87-93.
  78. Fan, Q., Sirkar, K.L., Michniak, B. Iontophoretic transdermal drug delivery system using a conducting polymeric membrane. J. Membrane Science, (2008), 321, 240-249.
  79. Sintov, A.C., Zhang, P., Michniak-Kohn, B.B. Cutaneous biotransformation of N-(4- bromobenzoyl)-S,S-dimethyliminosulfurane and its product, 4-bromobenzamide,   leading to percutaneous penetration enhancement of drugs: initial evidence using hydrocortisone. J. Controlled Release, (2009), 133, 44-51.
  80. Cheuvront, S.N., Ely, B.R., Kenefick, R.W., Michniak-Kohn, B., Rood, J., Sawka, M.N. No effect of nutritional adenosine receptor antagonists on exercise performance in the heat. American
  81. J. Physiology Regulatory Integrative & Comparative Physiology (2008), 296 (2), 394-401.

  82. Ganio, M.S., Armstrong, L.E., Johnson, E. C., Klau, J.F., Ballard, K., Casa, D.J., Michniak- Kohn, B., Kaushik, D., Maresh, C.M. Effect of quercetin supplementation on maximal aerobic capacity. Journal of Sports Science (2010), 28 (2), 201-208.
  83. Murthy, N.S., Bedoui, F., Kilfoyle, B., Iovine, C., Michniak-Kohn, B., Kohn, J.  Monitoring thickness and viscoelastic properties of skin in liquid environments using quartz crystal microbalance. J. Pharm. Sci., (2011) 100 (2), 530-535.
  84. Batheja, P., Song, Y., Wertz, P., Michniak-Kohn, B. Effects of growth conditions on the barrier properties of a human skin equivalent. Pharm. Research (2009), 26 (7), 1689-1700.
  85. Kaushik, D., Costache, A., Michniak-Kohn, B. Percutaneous penetration modifiers and formulation effects:  Part I. International J. of Pharmaceutics (2010), 386, 42-51.
  86. Kaushik, D., Costache, A., Michniak-Kohn, B. Percutaneous penetration modifiers and formulation effects: Thermal and Spectral Analyses. AAPS Pharm Sci. Tech. (2010) Sept. 11 (3) 1068-83.
  87. Rai, V., Ghosh, I., Bose, S., Silva, S.M.C., Chandra, P., Michniak-Kohn, B.A transdermal review on permeation of drug formulations, modifier compounds and delivery methods. J. Drug Delivery Science & Technology (2010) 20 (2), 75-87.
  88. Valenzuela, L., Michniak, B., Kohn, J. Variability of water uptake studies of biomedical polymers, Journal of Applied Polymer Science (2011), n/a. doi: 10.1002/app.33485, and (2011), 121, 1311-1320.
  89. Pingali, K., Mendez, R., Lewis, D., Michniak-Kohn, B., Muzzio, F. Mixing order of silica and magnesium stearate-Influence on powder and tablet properties, International Journal of Pharmaceutics (2011), 409 (1-2), 269-277.
  90. Pingali, K. Mendez, R. Lewis, D., Michniak-Kohn, B., Cuitino, A., Muzzio, F. Evaluation of strain induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions, Drug Development and Industrial Pharmacy (2010), Early Online, 1-9 and (2011), 37 (4), 428-435.
  91. Kaushik, D., O’Fallon, K., Clarkson, P., Dunne, C.P., Conca, K.R., Michniak-Kohn, B. Comparison of quercetin pharmacokinetics following oral and buccal supplementation in humans. Journal of Food Science, (2012), Oct 24. Doi: 10.111/j.1750-3841.2012.02934.x. [Epub ahead of print] PMID: 23094941 and (2012) Vol. 77 (11), November, pp. H 231-238.
  92. Rai, V., Terebetski, J., Silva, S., Michniak-Kohn, B. Human Skin Equivalents (HSEs) as an alternative for transdermal permeation, phototoxicity and cytotoxicity studies. Transdermal (2010), 2 (3) May, 5-8.
  93. Falcone, R., Michniak-Kohn, B. Under the Skin. Pharmaceutical Manufacturing and Packing Sourcer, (2010), May, pp. 26-31.
  94. Batheja,P. Sheihet, L., Kohn, J., Singer, A., Michniak-Kohn, B. Topical drug delivery by a polymeric nanosphere gel: formulation optimization and in vitro and in vivo distribution studies. Journal of Controlled Release (2011) 149, 159-167 and (2010),  doi:10.1016/j/jconrel.2010.10.005.
  95. Hu, L., Michniak-Kohn, B. Enhanced in vitro transbuccal drug delivery of ondansetron HCl.International J. of Pharmaceutics, (2011) 404, 66-74; doi:10.1016/j.ijpharm. 2010.10.052.
  96. Michniak-Kohn, B. and Shah, K.R.  Patchless transdermal drug delivery. Transdermals, 2011 (March), pp. 5-11.
  97. Rai, V., Dayan, N., Michniak-Kohn, B. A comparative evaluation of photo-toxic effect of fractionated melanin and its relationship to cell protection activity in different cell lines. Toxicity In Vitro (2011), 25, 538-544 and doi: 10.1016/j.tiv.2010.11.017 2010 EPublication.
  98. Rai, V., Tan, H.S., Michniak-Kohn, B. Effect of pre-formulation parameters on permeation of naltrexone (NTX)- HCl across buccal mucosa. Int. J. Pharm. (2011), 411, 92-97 and doi: 10.1016/j.ijpharm.2011.03.046.
  99. Meng, X., Yang, D., Keyvan, G., Michniak-Kohn, B., Mitra, S. Synthesis and immobilization of microscale drug particles in polymeric films, (2011), Colloids and Surfaces B.: Biointerfaces (2011), 86 (1), 181-188.
  100. Hu, L., Silva, S.M.C., Damaj, B.B., Martin, R., Michniak-Kohn, B.B. Transdermal and transbuccal drug delivery systems: Enhancement using iontophoretic and chemical approaches. Int. J. Pharm., (2011), 421, 53-62 and doi: 10.1016/j.ijpharm.2010.10.052.
  101. Zhang, J., Michniak-Kohn, B. Investigation of microemulsion microstructures and their relationship to transdermal permeation of model drugs: ketoprofen, lidocaine and caffeine. International Journal of Pharmaceutics (2011), 421, 34-44.
  102. Wei, R., Simon, L., Hu, L., Michniak-Kohn, B. Effects of iontophoresis and chemical enhancers on the transport of lidocaine and nicotine across buccal mucosa. Pharmaceutical Research,  (2012), 29 (4), 961-971.
  103. Ghosh, I., Michniak-Kohn, B. A comparative study of Vitamin E TPGS/HPMC supersaturated system and other solubilizer/ polymer combinations to enhance the permeability of a poorly soluble drug through the skin. Drug Development & Industrial Pharmacy (2012), doi:10.3109/03639045.2011.653363.
  104. Sievens-Figueroa, L., Bhakay, A., Jerez-Rozo, J.I., Pandya, N., Romanach, R., Michniak-Kohn, B., Iqbal, Z., Biligili, E., Dave, R. Preparation and characterization of hydroxypropyl methyl cellulose films containing stable BCS Class II drug nanoparticles for pharmaceutical applications. Int. J. Pharmaceutics (2012), 423, 496-508. Listed as one of top 25 most downloaded articles for 2012 from Int. J. Pharm. Sci.
  105. Silva, S.M.C., Hu, L. Sousa, J.J.S., Pais, A.A.C.C., Michniak-Kohn, B. A combination  of nonionic surfactants and iontophoresis to enhance the transdermal drug delivery of ondrasetron HCl and diltiazem HCl.  European Journal of Pharmaceutics and Biopharmaceutics (2011), doi: 10.1016/j.ejpb.2011.11.010 and (2012), 80, 663-673.
  106. Valenzuela, L.M., Zhang, G., Flach, C., Murthy, S., Mendelsohn, R., Michniak-Kohn, B., Kohn, J. Multiscale analysis of water uptake and erosion in biodegradable polyarylates. Polymer Degradation & Stability (2012), 97, 410-420.
  107. Zheng, Z., Michniak-Kohn, B. Tissue Engineered Human Skin Equivalents.
    Pharmaceutics ISSN 1999-4923 www.mdpi.com/journal/pharmaceutics doi: 10.3390/pharmaceutics4010026, (2012), 4, 26-41.
  108. Meng, X., Yang, D., Keyvan, G., Michniak-Kohn, B., Mitra, S. Synthesis and immobilization of micro-scale drug particles in presence of cyclodextrins. Colloids and Surfaces B: Biointerfaces (2011), doi:10.1016/j.colsurfb.2011.11.043.
  109. O’Fallon, K., Kaushik, D., Michniak-Kohn, B., Dunne, P., Zambraski, E., Clarkson, P. Quercetin does not attenuate changes in markers of muscle function or inflammation after eccentric exercise. International Journal of Sports Nutrition and Exercise Metabolism (2013), in press.
  110. Elele, E., Shen, Y., Susalrla, R., Khusid, B., Keyvan, G., Michniak-Kohn, B. Electrodeless electro-hydrodynamic drop-on-demand encapsulation of drugs into porous polymer films for fabrication of personalized dosage units. Journal of Pharmaceutical Sciences (2012), doi 10.1002/jps.23165.
  111. Ghosh, I., Michniak-Kohn, B. Design and characterization of submicron formulation for a poorly soluble drug: The effect of Vitamin E TPGS and other solubilizers on skin permeability enhancement. International J. of Pharmaceutics (2012), 434, 90-98.
  112. Rahman, A., Frenchek, S., Kilfoyle, B., Patterkine, L., Rahman, A., Michniak-Kohn, B. Diffusion kinetics and permeation concentration of human stratum corneum characterization by terahertz scanning reflectometry. Drug Development & Delivery (2012), May, Vol. 12 (4), pp.43- 49.
  113. Sharp, M.A., Hendrickson, N.R., Staab, J.S., McClung, H.L., Nindl, B.C., Michniak- Kohn, B. Effects of short-term quercetin supplementation on soldier performance. The Journal of Strength & Conditioning Research, 2012, 26 (7), S53-60.
  114. Kilfoyle, B.E., Sheihet, L., Zheng, Z., Laohoo, M., Kohn, J., Michniak-Kohn, B. Development of paclitaxel-TyroSpheres for topical skin treatment. Journal of Controlled Release (2012), 163, 18-24 and doi:10.1016/j.jconrel.2012.06.021.
  115. Ghosh, I., Michniak-Kohn, B. Influence of critical parameters of nanosuspension formulation on the permeability of a poorly soluble drug through the skin-A case Study. AAPS- Pharm. Tech. (2013), doi: 10:1208/s12249-013-9995-4.
  116. Zhang, J., Sintov, A.C., Michniak-Kohn, B. Investigation of DSC method for microemulsion formulation: microstructure characterization. J. Interfacial and Colloidal Science (2013), under review.
  117. Bose, S., Du, Y., Takhistov, P., Michniak-Kohn, B. Formulation optimization and topical delivery of quercetin from solid lipid based nanosystems. Int. J. Pharmaceutics (2013), 441, 56-66.
  118. Sievens-Figueroa, L., Pandya, N., Bhakay, A., Keyvan, G., Michniak-Kohn, B., Bilgili, E., Dave, R.N. Using USP I and USP IV for discriminating dissolution rates of nano- and microparticle-loaded pharmaceutical strip films. AAPS PharmSciTech. (2012), Dec., 13 (4), 1473-82.
  119. Bose, S., Michniak-Kohn, B. Preparation and characterization of lipid based nanosystems for topical delivery of quercetin. European J. Pharm. Sci. (2012) Dec 13. doi:pii: S0928-0987(12)00477-0. 10.1016/j.ejps.2012.12.005. [Epub ahead of print] and (2013), 48, 442- 452.
  120. Zhang, Z., Tsai, P., Ramezanli, T., Michniak-Kohn, B. Polymeric nanoparticle-based topical delivery systems for the treatment of dermatological conditions.  WIREs Nanomedicine & Nanobiotechnology (2013), doi: 10.1002/wnan.1211 and May-June; 5 (3), 205-218. PMID 23386536
  121. Susarla, R., Sievens-Figueroa, L., Bhakay, A., Shen, Y., Jerez-Rozo, J. L., Engen, W., Khusid, B., Biligili, E., Romanach, R., Morris, K.R., Michniak-Kohn, B., Dave, R. N. Fast drying of biocompatible polymer films loaded with poorly water soluble drugs nano-particles via low temperature forced convection. Int. J. Pharm. (2013), 445, 93-103.
  122. Zhang, Z., Kilfoyle, B., Sheihet, L., Kohn, J. Michniak-Kohn, B. Novel nanospheres that deliver actives to skin layers. Proceedings of the 21st  COLAMIQC (Congreso Latinoamericano e Iberico de Quimicos Cosmeticos) Transamerica Expo Center, Sao Paolo, Brazil, May 14-16th  2013.
  123. Silva, S. M.C., Sousa, J. J. S., Marques, E., Pais, A.A.C.C., Michniak-Kohn, B.B. Structure activity relationships in alkylammonium C12-gemini surfactants used as dermal enhancers. AAPS Journal, 2013, DOI: 10.1208/s12248-013-9518-y. Published on line 20 August 2013.
  124. Sun, X.L., Tsai, P-C., Bhat, R., Bonder, E. M., Michniak-Kohn, B., Pietrangelo, A. Thermoresponsive block copolymer micelles with tunable pyrrolidone-based polymer cores: Structure/Property correlations and application as drug carriers. Journal of Materials Chemistry B (2014), under review.
  125. Terebetski, J. and Michniak-Kohn, B. Combining Ibuprofen Sodium with Cellulosic Polymers:  A Deep Dive into Mechanisms of Prolonged Supersaturation. Int. J. Pharm. (2014), 475 (1-2), 536-546.
  126. Terebetski, J. and Michniak-Kohn, B.  Probing the speciation of ibuprofen in the presence of polymers during in vitro supersaturation. Drug Development & Industrial Pharmacy (2014). In press.
  127. Terebetski, J. Cummings, J. J., Fauty, S.E. and Michniak-Kohn, B. Combined use of crystalline sodium salt and polymeric precipitation inhibitors to improve pharmacokinetic profile of ibuprofen through supersaturation. AAPS Pharm. Sci.Tech. (2014), 15 (5), 1334-1344.
  128. Palma, F., Michniak-Kohn, B., Valenzuela, L.M., Perez-Correa, J.R. Assessing the impact of plasticizers on chitosan-gelatin edible film properties. Food Hydrocolloids (2014). Submitted.
  129. Dorrani, M., Kaul, M., Pilch, D., Parhi, A., LaVoie, E.J., Michniak-Kohn, B. TXA497 as a topical antibacterial agent: Comparative anti-Staphylococcal, skin deposition, and skin permeation studies with muciprocin. Int J. Pharmaceutics (2014), 476, 199-204.
  130. Hernandez, E., Pawar, P., Wang, Y., Velez, N., Keyvan, G., Michniak-Kohn, B.,  Muzzio, F., Cuitino, A., Romanach, R.J. Prediction of dissolution profiles by non-destructive near infrared spectroscopy in tablets subjected to different levels of strain. Int. J. Pharm., 2014. In preparation.
  131. Tsai, P.-C., Zhang, Z., Roberts, K., Florel, C, Michniak-Kohn, B. Evaluation & characterization of decellularized porcine mesothelial extracellular matrix for enhancing skin regeneration, 2014. In preparation.
  132. Dorrani, M., Garbuzenko, O., Minko, T., Michniak-Kohn, B., Topical Delivery of siRNA by Novel Ultradeformable Liposomal System to Knockdown the Over Expression of BRAF Protein Involved in Cell Proliferation Pathways in Melanoma, 2014. In preparation.
  133. Dorrani, M., Ramreddy, S., Joshi, V., Michniak-Kohn, B., A Synthetic Membrane for Studying In-Vitro Transdermal Penetration of Actives, 2014. In preparation.

Pending Provisional, Full Patent Applications & Disclosures (5)

  1. Thakur, R.A., Florek, C.A. Kohn, J.B., Michniak-Kohn, B.B. Electrospun Matrices for the Delivery of Hydrophilic and Lipophilic Compounds. Provisional Patent U.S. Serial No. 60/862, 767. Filing Date: October 24, 2006. International Patent Application No. PCT/US07/82459 filed on October 31, 2
  2. Kohn, J., Michniak, B. Devore, D., Sheihet, L. Chandra, P. Batheja, P. Controlled Release of Actives in Skin. Provisional Patent U.S. Serial No. 60/887,553. Filing Date: January 31, 2007. International Patent Application PCT/US08/ 52758. Patent Application Publication US 2009/0317472 A1, Dec 24, 2009. U.S. Patent 8,414,871 B2 issued April 9th, 2013.
  3. Damaj, B.B., Martin, R., Michniak-Kohn, B. Long-Sheng Hu. Enhanced transbuccal drug delivery system and compositions. US Patent Application US 2013/0178463 A1 July 11, 2013. Licensed in 2012 to Apricus Biosciences, Inc. California. Returned to Rutgers University 2014.
  4. Muzzio, F., Takhistov, P. Michniak-Kohn, B., Pharmaceutical preparations having   individualized dosage and structure. International Patent Application PCT/ US10/55752, filed November 6, 2010 and International Patent Publication No. WO 2011/057164 A1- May 12, 2011. United States Patent Publication US 2013/0053446 A1 Issued February 28, 2013.
  5. Takhistov, P. Muzzio, F. Michniak-Kohn, B. Novel Transdermal Dosage Forms in Form of Printed Array via Drop-on-Demand Technology. RU Docket # 2013-069. Filed January 2013.

Books (2) & Book Chapters (35)

  1. Michniak-Mikolajczak, B., Barry, B.W.  Interaction of stratum corneum with water vapour. In Physical Nature of the Skin.  Edited by Marks, R.M., Barton, S. P., Edwards C.  (1988) MTP Press Ltd., U.K. ISBN 0-85200-977-1, pp. 101-112.
  2. Michniak, B.B., Player, M.R., Chapman, J.M., Jr., Sowell, J.W., Sr. Studies of in vitro (trans)dermal absorption of hydrocortisone acetate using azone analogs as enhancers.  Prediction of Percutaneous Penetration:  Methods, Measurement and Modelling.  Vol. 3b (Eds. Brain, K.R., James, V.J., Walters, K.A.) STS Publishing, Cardiff, U.K., ISBN 0-948917-067, pp. 277-286 (1993).
  3. Michniak, B.B.  Amines and amides as penetration enhancers.  In Percutaneous Penetration Enhancers.  Eds. Smith, E.W., and Maibach, H. I.  CRC Press, Boca Raton, FL (1995) ISBN 0- 8493-2605-2, pp. 79-89.
  4. Michniak, B.B.  Azone analogues as penetration enhancers.  In Percutaneous Penetration Enhancers.  Eds. Smith, E.W. and Maibach, H. I.  CRC Press, Boca Raton, FL (1995), ISBN 0- 8493-2605-2, pp. 183-194.
  5. Fuhrman, Jr., L.C., Michniak, B.B., and Bennett, C.F.  In vitro dermal delivery of encapsulated ISIS 3082:  a species and liposomal entrapment technique comparison.  Prediction of Percutaneous Penetration, Brain, K.R., James, V.J., and Walters, K.A. (Eds.), Vol. 4b (1995). STS Publishing, Cardiff, U.K. ISBN 0948917105, pp. 113-116.
  6. Fuhrman, Jr., L.C., Michniak, B.B., and Godwin, D.A.  Studies of in vitro (trans)dermal absorption of hydrocortisone utilizing novel enhancer compounds:  a species comparison. Prediction of Percutaneous Penetration, Brain, K.R., James, V.J., and Walters, K.A. (Eds.), Vol. 4b (1995). STS Publishing, Cardiff, U.K. ISBN 0948917105, pp. 117-120.
  7. Michniak, B.B. and Kasting, G.B.  Topical formulations: design and development.  Technomic Publications (1998).  BOOK.
  8. Wertz, P.W. and Michniak, B.B.  Barrier Function of Stratum Corneum and Epidermal Lipid Metabolism.  In Biomedical Modulations of Skin Reactions in Dermal and Transdermal Drug Delivery.  Kydonieus, A.F. and Wille, J. J. Editors November, 1999. ISBN 0-8493-2117-4. CRC Press, Boca Raton, FL.
  9. Michniak, B.B., Wertz, P.W.  Ceramides and Lipids.  In Handbook of Cosmetic Science and Technology, edited by Barel, A., Maibach, H.I. and Paye, M. Chapter 31, pp.  361-367. Marcel Dekker Inc., NY (2001).
  10. Wertz, P. and Michniak, B.B. Sebum. In Cosmeceuticals edited by Maibach H.I. and Elsner, P. Marcel Dekker, Inc., NY, Chapter 5, pp. 45-56. (2000). ISBN # 0-8247-0305-7.
  11. Asbill, C .S., El-Kattan, A.F., Michniak, B.B. Enhancement of Transdermal Drug Delivery: Chemical and Physical Approaches. In Critical Reviews in Therapeutic Drug Carrier Systems edited by Bruck, S.D., Begell House, Inc. Publishers, 2000, 17 (6), 623-660.
  12. Michniak, B.B., El-Kattan, A. F. Transdermal Delivery of Drugs. In Polymeric Biomaterials edited by Dumitriu, S., 2nd Edition, Revised and Expanded, Marcel Dekker Inc., N.Y., Chapter 39, pp. 1007-1030, (2002). ISBN 0-8247-0569-6.
  13. Michniak, B.B., Seyda, A., Abramson, S., Meidan, V., Kohn, J. Chapter 11: Tissue Engineering. In Biomedical Engineering Principles,
    1st Edition, pps. 579-636. Eds. Ritter, A.B., Reisman, S., Michniak, B.B. CRC Taylor and Francis Group, Boca Raton, FL., 2005. ISBN: 0-8247-9616-0. EDITOR AS WELL AS BOOK CHAPTER.
  14. Wertz, P., Michniak, B.B. Water-lipid interaction. In Bioengineering and the Skin: Water and Stratum Corneum (2nd edition) Ed. Fluhr, J. CRC Press, Boca Raton FL (2004). ISBN # 0-8493- 1443-7, Chapter 1, pp. 3-14.
  15. Michniak, B., Wertz, P. Hydration and Lipids. In Bioengineering and the Skin: Water and Stratum Corneum (2nd Edition) Ed. Fluhr, J. CRC Press, Boca Raton FL (2004). ISBN # 0-8493- 1443-7, Chapter 29, pp. 359-370.
  16. Michniak-Kohn, B., Wertz, P.W. Al-Khalili, M., Meidan, V.M. Skin: Physiology and Penetration Pathways. Chapter 3, pp. 77-100.  In Delivery System Handbook for Personal Care and Cosmetic Products. Ed. Rosen, M. R. Noyes Publications: William Andrew Publishing, Inc., Norwich, NY (2005). ISBN 0-8155-1504-9.
  17. Michniak, B.B., Meidan, V. and Thakur, R. Biomaterials. Chapter 21, pp. 585-627.  In Martin’s Physical Pharmacy and Pharmaceutical Sciences 5th edition, Lippincott Williams and Wilkins (2005).
  18. Wertz, P. and Michniak, B.B. Sebum.  Chapter 5, pp. 45- 56. In Cosmeceuticals edited by Maibach H.I. and Elsner, P. Marcel Dekker, Inc., NY. New Edition  (2004). ISBN # 0-8247- 0305-7.
  19. Wang, Y. Michniak, B. B.  The Transdermal Patch. The World Book Encyclopedia, 2004 (Internet only- www.worldbook.com).
  20. Thakur, R., Song, Y., Michniak, B. Chapter 17: Chemical Enhancers in  “Skin Delivery Systems: Transdermals, Dermatologicals, and Cosmetic Actives”. Edited by Wille, J.J. Blackwell  Publishing (2006). ISBN # 978-0-8138-0848-2, pp. 277-295.
  21. Thakur, R., Wang, Y., and Michniak, B., Essential Oils and Terpenes. Chapter 13 in Percutaneous Penetration Enhancers- Volume 2, pp. 159-173. Eds. Smith, E.W. and Maibach, H. (2006). ISBN # 978-0-8493-2152-8.
  22. Asbill, C.S., Bumgarner, G.W. and Michniak, B., The use of skin alternatives for testing percutaneous penetration. Chapter 21 in  Percutaneous Penetration Enhancers- Volume 2, pp. 311-318. Eds. Smith, E.W. and Maibach, H.  (2006). ISBN # 978-0-8493-2152-8.
  23. Michniak, B., Thakur, R., Batheja, P. Basic biopharmaceutics of buccal and sublingual absorption in Enhancement in Drug Delivery, Touitou, E. and Barry, B.W. (Eds.) CRS Press, Boca Raton, FL (2007). ISBN # 0-8493-3203-6. Pp. 175-202.
  24. Michniak, B.B., Wertz, P.W.  Ceramides and Lipids.  In Handbook of Cosmetic Science and Technology, edited by Paye, M. Barel, A.O., and Maibach, H.I. Taylor and Francis, NY 2nd Edition (2006). Chapter 21, pp. 281-288.  ISBN # 1-57444-824-2.
  25. Wertz, P.W. and Michniak, B.B. Skin Lipid Structure and Function. In Dermal Absorption and Toxicity Assessment, Editors: Walters, K. and Roberts, M. 2nd Edition (2007).
  26. Michniak-Kohn, B.B., Batheja, P. and Thakur, R. Changes in the Skin Permeability Barrier with Aging. In Handbook of Skin Aging: Market Prospective, Pharmacology, Formulation and Evaluation, Ed. Dayan, N. in series “ Breakthroughs in Personal Care, Cosmetic and Topical Delivery/Pharmaceutical Technologies, series Editor Rosen, M.R. William Andrew Publishers of Norwich, NY (2008), ISBN # 978-0-8155-1584-5.
  27. Kaushik, D., Kilfoyle, B., Thakur, R., Michniak-Kohn, B. Microneedles-minimally invasive transdermal delivery technology. In “Handbook of Non-Invasive Drug Delivery Systems”. Ed. Kulkarni,V.S. William Andrew Publishing, NY, (2010), Chapter 6, pp. 135-164. ISBN # 978-0-8155-2025-2.
  28. Meidan, V. and Michniak-Kohn, B.  Ultrasound-based technology for skin barrier permealization. In “Handbook of Non-Invasive Drug Delivery Systems”. Ed. Kulkarni, V.S. William Andrew Publishing, NY, (2010), Chapter 5, pp. 119-134. ISBN # 978-0-8155-2025-2.
  29. Hu, L., Batheja, P., Meidan, V., Michniak-Kohn, B. Iontophoretic transdermal drug delivery. In “Handbook of Non-Invasive Drug Delivery Systems”. Ed. Kulkarni, V.S. William Andrew Publishing, NY, (2010), Chapter 4, pp. 95-118. ISBN # 978-0-8155-2025-2.
  30. Kilfoyle, B., Kaushik, D., Bose, S. Michniak-Kohn, B. Challenges in delivery of quercetin and curcumin to the skin, in “Formulating Packaging, and Marketing of Natural Cosmetic Products” editors Dayan, N. and Kromidas, L. John Wiley & Sons, Inc. Publishers, (2011), Chapter 14, pp. 259-286. ISBN # 978-0-470-484408-1.
  31. Michniak-Kohn, B. Editor of “Structure and Function of Human Skin” section for Harry’s Cosmeticology 9th  edition, 2014. Chemical Publishing Company Revere, MA. Editor-in-Chief Rosen, M. Authors in section: Menon, G., Pappert, A., Wertz, P., Sharma, N., Burke, K.,
    Langerveld, A., Dayan, N., Poillot, A. and Polla, B. and Polla, A. In preparation.
  32. Zheng, Z., Ramezanli, T., Tsai, P., Michniak-Kohn, B. Drug Delivery Systems based on Tyrosine-derived Nanospheres (Tyrospheres) in “Nanotechnology and Drug Delivery Volume I - Nanoplatforms in Drug Delivery” Guest Editor Arias, J. Chapter 6, pp. 210-232, L. Taylor & Francis Group, CRC Press, ISBN : 978-1-9947-5, 2015.
  33. Ramezanli, T., Tsai, P., Dorrani, M. and Michniak-Kohn, B. Aromatic iminosulfuranes: A novel class of transdermal penetration enhancers. In new edition of “Percutaneous Penetration Enhancers”, edited by Maibach, H. and Dragcevic-Curic, N. 2015. In press.
  34. Tsai, P., Lee, S. and Michniak-Kohn, B. In Vitro Methods for Screening Transdermal Formulations” in “Advances and Challenges in Transdermal Delivery”. E Book edited by Sachdeva V., 2015. In preparation.
  35. Zhang, Z., Ramezanli, T., Karry, K. Shah, K., Michniak-Kohn, B. “Transdermal delivery of drugs using patches and patchless delivery systems” in Drug Delivery: Principles and Applications”. Editors: Wang, B., Hu, L. & Siahaan, T. Wiley Series in Drug Discovery and Development, Wiley Press, US. , 2015. In preparation.
  36. Zhang, Z., Ramezanli, T., Karry, K. Shah, K., Michniak-Kohn, B. “Advanced formulation techniques including innovative materials” in Cosmetic Formulation: Principles and Practice, edited by Benson, H., Roberts, M., Leite e Silva, V. and Walters, K. and Surber, C., April 2015. In preparation.
  37. Ramezanli, T. and Michniak-Kohn, B. Transdermal Delivery of Large Molecules in Shao, J. (editor) Non-Invasive Macromolecule Delivery Guide. Published by Catalent Applied Drug Delivery Institute, June 2014.

 

Bozena B. Michniak-Kohn

Professor

 

  • : (848) 445 3589
    Fax: (732) 445 5006

  • DEPARTMENT Department of Pharmaceutics
    Rutgers University
  • COUNTRY USA