Publications

• Vehik K, Hamman RF, Lezotte D, Norris JM, Klingensmith G, Bloch C, Rewers M, Dabelea D. Increasing incidence of type 1 diabetes in 0-17 year old Colorado youth. Diabetes Care 2007; 30:503-9. (PMID: 17327312)
• Dabelea D, Mayer-Davis EJ, Pande A, D’Agostino Jr RB, Liese AD, Vehik KS, Narayan KMV, Zeitler P, Hamman RF. Association of Intrauterine Exposure to Maternal Diabetes and Obesity with Type 2 Diabetes in Youth: The SEARCH Case-Control Study. Diabetes Care 2008 Jul;31(7):1422-6. (PMID: 18375420)
• Vehik K, Hamman RF, Lezotte D, Norris JM, Klingensmith G, Rewers M, Dabelea D. Trends in High-Risk HLA Susceptibility Genes Among Colorado Youth with Type 1 Diabetes. Diabetes Care 2008 Jul; 31(7):1392-6. (PMID: 18356404)
• TEDDY Study Group. The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Annals of the New York Academy of Sciences 2008 Dec; 1150:1-13. (PMID: 19120261)
• Vehik K, Hamman RF, Lezotte D, Norris JM, Klingensmith G, Dabelea D. Childhood growth and age at diagnosis with type 1 diabetes among Colorado youth. Diabetic Medicine 2009 Oct;26(10):961-7. (PMID: 19900226)
• Richesson R, Vehik K. Patient Registries: utility, validity and inference. Advances in Experimental Medicine and Biology 2010;686:87-104. (PMID: 20824441)
• Crume TL, Ogden L, West NA, Vehik KS, Scherzinger A, Daniels S, McDuffie R, Bichoff K, Hamman RF, Norris JM, Dabelea D. Association of Exposure to Diabetes In Utero with Adiposity and Fat Distribution in a Multi-Ethnic Population of Youth: The EPOCH Study. Diabetologia 2011 Jan; 54(1):87-92. (PMID: 20953862)
• Vehik K, Dabelea D. The Changing Epidemiology of Type 1 Diabetes: Why is it Going Through the Roof? Diabetes Metabolism Research and Reviews 2011 Jan;27(1)3-13. (PMID: 21218503)
• Vehik K, Haller MJ, Beam CA, Schatz DA, Wherrett DK, Sosenko JM, Krischer JP for the DPT-1 Study Group. Islet Autoantibody Seroconversion in the DPT-1 Study: Justification for Repeat Screening throughout Childhood. Diabetes Care 2011 Feb;34(2):358-62. (PMID: 21270193)
• Lernmark B, Johnson SB, Vehik K, Smith L, Ballard L, Baxter J, McLeod W, Roth R, Simell T on behalf of the TEDDY Study Group. Enrollment Experiences in a Pediatric Longitudinal Observational Study: The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Contemp Clin Trials 2011 Jul;32(4):517-23. (PMID: 21419878)
• Vehik K, Cuthbertson D, Ruhlig H, Krischer JP. Long-term Outcome of those Treated with Oral Insulin: DPT-1 Oral Insulin Trial. Diabetes Care 2011 Jul;34(7):1585-90.  (PMID: 21610124)
• Vehik K, Beam CA, Mahon JL, Schatz DA, Haller MJ, Sosenko JM, Skyler JS, Krischer JP. Development of Autoantibodies in the TrialNet Natural History Study (NHS). Diabetes Care 2011 Sep;34(9):1897-1901. (PMID: 21750277)
• Hagopian WA, Erlich H, Lernmark A, Rewers M, Zeigler AG, Simell O, Akolkar B, Vogt R Jr, Blair A, Ilonen J, Krischer J, She J and the TEDDY Study Group. The environmental determinants of diabetes in the young (TEDDY) genetic criteria and international diabetes risk screening of 421,000 infants. Pediatr Diabetes 2011 Dec;12(8):733-43. (PMID: 21564455)
• Elding Larsson H, Vehik K, Bell R, Dabelea D, Dolan L, Pihoker C, Knip M, Veijola R, Lindblad B, Samuelsson U, Holl R, Haller MJ, TEDDY, SEARCH, SWEDIAKIDS, DPV and FINNISH DIABETES. Diabetes Care 2011, Nov;34(11):2347-52. (PMID: 21972409)
• Vehik K, Dabelea D. Why are C-section deliveries linked to childhood type 1 diabetes? Diabetes 2012 Jan;61(1):36-7. (PMID: 22187373)
• Baxter J, Vehik K, Johnson SB, Lernmark B, Roth R, Simell T, for the TEDDY Study Group. Differences in recruitment and early retention among ethnic minority participants in a large pediatric cohort: The TEDDY Study. Contemp Clin Trials 2012 Jul;33(4):633-640. (PMID: 22484339)
• Vehik K, Cuthbertson D, Boulware D, Beam C, Rodriguez H, Legault L, Hyytinen M, Rewers M, Schatz DA, Krischer JP. Performance of glycated hemoglobin (HbA1c) as an early diagnostic indicator of type 1 diabetes in children and youth. Diabetes Care 2012 Sep;35(9):1821-25. (PMID: 22699293)
• Bollepalli S, Smith LB, Vasquez A, Rodriguez H, Vehik K. Addressing the burdens of type 1 diabetes in youth. Clinical Practice 2012, 9(4):409-24.
• Jaiswal M, Crume T, Vehik K, Scherzinger A, Stamm E, Hamman RF, Dabelea D. Is low birth weight associated with adiposity in contemporary US youth? The Exploring Perinatal Outcomes among Children (EPOCH) Study. Journal of Developmental Origins of Health and Disease 2012 Jun;3(3):166-172. (PMID: 23050071)
• Salami F, Landin M, Hyoty H, Vaziri-Sani F, Aronsson CA, Vehik K, Delli A, Hagopian WA, Rewers M, Ziegler AG, Simell O, Akolkar B, Krischer J, She J, Lernmark A and the TEDDY Study Group. Detection of Lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes. International Journal of Probiotics and Prebiotics 2012 Vol.7, No.3/4:135-144.
• Aronsson CA, Vehik K, Yang J, Uusitalo U, Hay K, Joslowski G, Riikonen A, Ballard L, Virtanen S, Norris JM. Use of dietary supplements in pregnant women in relation to sociodemographic factors – a report from the Environmental Determinants of Diabetes in the Young (TEDDY) study. Public Health Nutr. 2013 Mar 4:1-13. (PMID: 23452986)
• Lee HS, Burkhardt BR, McLeod W, Smith S Eberhard C, Lynch K, Hadley D, Rewers M, Simell O, She JX, Hagopian B, Lernmark A, Akolkar B, Ziegler AG, Krischer JP and the TEDDY Study Group. Biomarker discovery study design for type 1 diabetes in the environmental determinants of diabetes in the young (TEDDY) study. Diabetes Metab Res Rev. 2014 Jul;30(5):424-34. (PMID: 24339168)
• Vehik K, Fiske SW, Logan CA, Agardh D, Cilio C, Hagopian W, Simell O, She JX, Briese T, Oikarinen S, Hyoty H, Ziegler AG, Rewers M, Lernmark A, Akolkar B, Krischer JP, Burkhardt BR and the TEDDY Study Group. Methods, quality control and specimen management in an international multi-center investigation of type 1 diabetes:  TEDDY. Diabetes Metab Res Rev. 2013 Oct;29(7):557-67. (PMID: 23674484)
• Larsson HE, Vehik K, Gesualdo P, Akolkar B, Hagopian WA, Krischer J, Lernmark A, Rewers M, Simell O, She JX, Ziegler A-G, Haller MJ and the TEDDY Study. Children followed in the TEDDY study are diagnosed with Type 1 diabetes at an early stage of disease. Pediatric Diabetes 2013 Aug 27. (PMID: 24034790)
• Vehik K, Ajami NJ, Hadley D, Petrosino JF, Burkhardt BR. The changing landscape of type 1 diabetes: recent developments and future frontiers. Curr Diab Rep. 2013 Oct;13(5):642-50. (PMID: 23912764)
• Andrén Aronsson C, Uusitalo U, Vehik K, Yang J, Silvis K, Hummel S, Virtanen SM, Norris JM; TEDDY Study Group. Age at first introduction to complementary foods is associated with sociodemographic factors in children with increased genetic risk of developing type 1 diabetes. Matern Child Nutr. 2013 Sept 13. (PMID: 24034553)
• Ahmadi Adl A, Qian X, Xu P, Vehik K, Krischer JP. Feature ranking based on synergy networks to identify prognostic markers in DPT-1. EURASIP J Bioinform Syst Biol. 2013 Sept 19;2013(1):12. (PMID: 24050757)
• Hummel S, Vehik K, Uusitalo U, McLeod W, Andren Aronsson C, Frank N, Gesualdo P, Yang J, Norris JM, Virtanen SM and the TEDDY Study Group. Infant feeding patterns in families with a diabetes history - observations from The Environmental Determinants of Diabetes in the Young (TEDDY) birth cohort study. Public Health Nutr. 2013 Nov 26:1-10. (PMID: 24477208)
• Yang J, Lernmark A, Uusitalo UM, Lynch KF, Veijola R, Winkler C, Larsson HE, Rewers M, She JX, Ziegler AG, Simell OG, Hagopian WA, Akolkar B, Krischer JP, Vehik K; the TEDDY Study Group. Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes. Int J Obes (Lond), 2014 Apr 3 EPUB (PMID: 24694666)
• Lin Y, Qian X, Krischer J, Vehik K, Lee HS, Huang S. A rule-based prognostic model for type 1 diabetes by identifying and synthesizing baseline profile patterns. PLoS One. 2014 June 13; 9(6):e91095. (PMID: 24926781)
• Liu E, Lee HS, Aronsson CA, Hagopian WA, Koletzko S, Rewers MJ, Eisenbarth GS, Bingley PJ, Bonifacio E, Simell V, Agardh D; TEDDY Study Group. Risk of pediatric celiac disease according to HLA haplotype and country. N Engl J Med, 2014 Jul 3;371(1):42-9. (PMID: 24988556)

Government Publications:

• Vehik KS, Jiménez JM, Lustig M, Coe TP., Evaluation of Programs Funded Through Tobacco Tax Allocations, Arizona Department of Health Services, Division of Public Health Services, Office of Health Planning, Evaluation and Statistics, Phoenix, Arizona.  November 1997.
• Dick W, Vehik K, Finch J, Bol K, Jacobellis J, Cancer and Poverty in Colorado: 1995-2000, Colorado Department of Public Health and Environment, Preventive Services Division, Denver, Colorado, August 2004.

Book Chapters:

• Richesson R, Vehik K. “Patient Registries: Utility, Validity and Inference”.  In: Posada M & Groft SC (ed). Rare Diseases Epidemiology, 1st ed., Springer, The Netherlands. 2010. [MEDLINE indexed: Adv Exp Med Biol. 2010;686:87-104.]
• Richesson RL, Vehik K.  “Patient Registries”.  In: Richesson RL & Andrews JE (ed). Clinical Research Informatics. Springer-Verlag: London. 2012;233-252.

Manuscripts Under Journal Review / Working Manuscripts:

• Snell-Bergeon JK, Rewers MJ, Norris JM, Lynch KF, Schatz D, Lernmark A, Vehik K. The Impact of Maternal and Birth Factors on the Risk of Developing Early Persistent Islet Auto-Antibodies in Children at High Risk for Developing Type 1 Diabetes: The Environmental Determinants of Type 1 Diabetes in the Young Study. In Submission to Diabetologia
• Lernmark A, Lee HS, Delli AJ, Farhadi Z, Torn C, Vehik K and the TEDDY Study Group. Effects of maternal smoking and gestational infections on birth size in The Environmental Determinants of Diabetes in the Young (TEDDY) study. In Submission to Journal of Perinatology
• Vehik K, Beam CA, Boulware D, Schatz DA, Krischer JP for the TrialNet Group. Autoantibody Reversion in the TrialNet Natural History Study.
• Vehik K, Cuthbertson D, Boulware D, Rodriguez H, Schatz DA, Krischer JP and the DPT-1 and TrialNet Natural History Study Groups. Rising Hemoglobin A1c in the Non-Diabetic Range Accelerates Time to Development of Type 1 Diabetes in High-Risk Relatives.
• Vehik K, Johnson SJ, Culbertson D, Xu P, Shor A, Krischer JP. Effects of exogenous insulin in relatives of patients with type 1 diabetes mellitus: Compliance vs. Intent to treat.

Invited Oral Presentations:

• Vehik K. Risk factors associated with hepatitis B virus among hemophiliacs. NCI Grand Rounds, 1996, Rockville, Maryland
• Vehik KS, Lustig M. Telepsychiatry:  An evaluation model for state funded programs. American Evaluation Association, 1997, San Diego, California
• Vehik K, Dick W, Finch J, Bol K, Jacobellis J. Cancer and Poverty in Colorado: 1995-2000. 4th Annual Colorado Cancer Conference, 2004, Denver, Colorado
• Vehik K, Kamboh MI, Marshall JA, Hamman RF, Hokanson J. The hepatic lipase promoter polymorphism modifies the relation between dietary starch and coronary heart disease. American Heart Association, 2004 Meeting, New Orleans, Louisiana
• Vehik K, Hamman RF, Lezotte D, Klingensmith GJ, Bloch C, Rewers M, Norris JM, Dabelea D. Increasing incidence of type 1 diabetes mellitus in Colorado (1978-2004). University of Colorado, Epidemiologic Exchange, 2006, Denver, Colorado
• Vehik K, Hamman RF, Lezotte D, Klingensmith GJ, Bloch C, Rewers M, Norris JM, Dabelea D. Increasing incidence of type 1 diabetes mellitus in Colorado (1978-2004). American Diabetes Association 66th Scientific Sessions, 2006, Washington, District of Columbia
• Crume TL, West NA, Scherzinger A, Daniels S, Vehik K, Hamman R, Norris J, Ogden L, Dabelea D. The impact of in utero exposure to diabetes on abdominal fat distribution among multi-ethnic youth. (ADA 69th Scientific Sessions 2009, New Orleans, LA)
• Vehik K, Beam CB, Haller MJ, Sosenko JM, Schatz DA, Mahon JL, Krischer JP, Skyler JS. Development of Autoantibodies in the TrialNet Natural History Study (NHS). American Diabetes Association 70th Scientific Sessions, 2010, Orlando, Florida
• Vehik K, Schatz D, Boulware D, Cuthbertson D, Beam C, Rodriguez H, Legault L, Rewers M, Krischer JP on behalf of the DPT-1, TEDDY, TRIGR and TrialNet Study Groups. Hemoglobin A1c as an indicator of Type 1 Diabetes in Pediatric and Adolescent Youth. Diabetologia (2011) 54:[Suppl1]80OR, S40. European Association for the Study of Diabetes 47th Annual Meeting, 2011, Lisbon, Portugal
• Richesson R, Pathak J, McLeod W, Blackmon G, Vehik K. Requirements and strategy for the development of a pediatric drug ontology. Int’l Conference on Formal Ontology in Information Systems, 2012, Grazm, Austria
• Vehik K, Cuthbertson D, Boulware D, Rodriguez H, Schatz D, Krischer JP and the Diabetes Prevention Trial-Type 1 and Type 1 Diabetes TrialNet Natural History Study Groups. Rising hemoglobin A1c in the non-diabetic range accelerates time to development of type 1 diabetes in high-risk relatives. European Diabetes Epidemiology Group Meeting, 2012, Swansea, UK

Published Abstracts (Invited Poster Presentations):

• Vehik K, Kamboh MI, Marshall JA, Hamman RF, Hokanson J. The hepatic lipase promoter polymorphism modifies the relation between dietary starch and coronary heart disease. Circulation 2004:110(17) Suppl.:824-25:3805
• Vehik K, Dabelea D, Chase M, Mayer-Davis E, Hamman RF. Maternal recall of birth weights of youth with and without diabetes: Validation by state birth certificate records. Am J Epidemiol 2005; 161 (Supple): S108
• Vehik K, Hamman RF, Lezotte D, Klingensmith GJ, Bloch C, Rewers M, Norris JM, Dabelea D. Increasing incidence of type 1 diabetes mellitus in Colorado (1978-2004). Diabetes 2006;55 (suppl. 1):A56. (ADA 66th Scientific Sessions, Washington, DC)
• Vehik K, Hamman RF, Lezotte D, Klingensmith GJ, Bloch C, Rewers M, Norris JM, Dabelea D. Increasing incidence of type 1 diabetes mellitus in Colorado (1978-2004). European Diabetes Epidemiology Group, 2007, Cambridge, UK
• Vehik K, Hamman RF, Lezotte D, Norris JM, Klingensmith GJ, Dabelea D. Trends in clinical presentation of type 1 diabetes among Colorado youth (1978-2004). Diabetes 2007;56 (suppl.1):1888P (ADA 67th Scientific Sessions, Chicago, IL)
• Nadeau K, West N, Sorenson E, Vehik K, Maahs DM, Zeitler P, Liese A, Mayer-Davis EJ, Hamman RF, Dabelea D. Reduced insulin sensitivity in youth with type 1 and type 2 diabetes. Diabetes 2008:57 (suppl.1):1804P (ADA 68th Scientific Sessions, San Francisco, CA)
• Vehik K, Scherzinger A, Stamm E, Hamman RF, Norris JM, Ogden LG, Dabelea D. Lower birth weight is associated with intramyocellular accumulation of lipids in youth: preliminary results from the EPOCH study. Diabetes 2008:57 (suppl.1):963P (ADA 68th Scientific Sessions, San Francisco, CA)
• Crume TL, West NA, Scherzinger A, Daniels S, Vehik K, Hamman R, Norris J, Ogden L, Dabelea D. The impact of in utero exposure to diabetes on abdominal fat distribution among multi-ethnic youth. Diabetes 2009:58(suppl.1): 259-OR (ADA 69th Scientific Sessions, New Orleans, LA)
• West NA, Vehik K, Crume T, Maligie M, Bischoff K, McDuffie R, Dabelea D. Exposure to diabetes in utero leads to increased adiposity and systolic blood pressure in children. Diabetes 2009:58(suppl.1):971P (ADA 69th Scientific Sessions, New Orleans, LA)
• Vehik K, Haller MJ, Xu P, Schatz DA, Krischer JP. Seroconversion in the DPT-1 Study: Evidence of triggering of autoimmune process at different ages and screening. Diabetologia  2009:52(Suppl1):277P  (EASD Annual Meeting, September 2009, Austria)
• Vehik K, Beam CA, Haller MJ, Sosenko JM, Schatz DA, Mahon JL, Krischer JP, Skyler JS. Development of Autoantibodies in the TrialNet Natural History Study (NHS). Diabetes 2010:59(suppl. 1):213OR (ADA 70th Scientific Sessions, Orlando, FL)
• Lernmark B, Bennett SJ, Vehik K, Ballard L, Baxter J, Mcleod W, Roth R, Simell T. Recruitment Experiences in the Environmental Determinants of Diabetes in the Young (TEDDY) Study – Predictors of Enrollment. Diabetes 2010:59(suppl. 1):1097P (ADA 70th Scientific Sessions, Orlando, FL)
• Vehik K, Beam CA, Boulware D, Schatz DA, Krischer JP, TrialNet Study Group. Autoantibody Reversion in the TrialNet Natural History Study. Diabetes 2011:60(suppl. 1):1286AudioPoster (ADA 71st Scientific Sessions, San Diego, CA)
• Yang J, Uusitalo U, Lynch K, Krischer J, Vehik K. Prevalence of obesity in young children genetically at-risk for type 1 diabetes. Diabetes 2012:61(suppl. 1):1226AudioPoster (ADA 72nd Scientific Sessions, Philadelphia, PA)
• Vehik K, Lynch K, Schatz D, Lernmark A, Bonifacio E, Ziegler AG, Hagopian W, She J-X, Rewers M, Simell O, Akolkar B, Krischer JP. Islet antibody remission and risk of type 1 diabetes in very young patients in the TEDDY Study. Immunology of Diabetes Society 2013:123 (13th International Congress, Lorne, Australia)
• Akolkar B, Vehik K, Lynch K, Lernmark A, Bonifacio E, Schatz D, Ziegler AG, Hagopian W, She J-X, Rewers M, Simell O, Krischer JP. The six-year incidence of diabetes associated autoantibodies in the genetically at-risk: The TEDDY Study. Immunology of Diabetes Society 2013:124 (13th International Congress, Lorne, Australia)
• Uusitalo U, Lee H-S, Aronsson CA, Vehik K, Yang J, Hummel S, Butterworth M,  Lernmark A, Hagopian W, Simell O, Ziegler AG, She J-X, Akolkar B, Rewers M, Krischer JP, Virtanen S, Norris J. Early infant feeding and islet autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study. Immunology of Diabetes Society 2013:98 (13th International Congress, Lorne, Australia)
• Larsson HE, Vehik K, Liu Xiang, Mike Haller, Akolkar B, Hagopian W, Krischer JP, Lernmark A, She J-X, Simell O, Ziegler AG, Rewers M. Increased weight or height gain in infants or toddlers does not predict early development of T1D: The Environmental Determinants of Diabetes in the Young Study. Immunology of Diabetes Society 2013:113 (13th International Congress, Lorne, Australia)