Professional Activities:

Research Projects:

  1. Decoding pain-related circuits in spinal cord using DREADDs
  2. The role of Gi/oproteins in morphine tolerance
  3. The Gabapentin pharmacological mechanism
  4. KCC2 roles in pain and hypertension

Major Accomplishments:

In Vivo:

  1. Expression of GRK6 in nucleus accumbens shell involved in rewarding effects
  2. GRK3 regulates L-DOPA-induced behavior in Parkinson's disease via its RGS domain

In Vitro:

  1. GRK4subfamily phosphorylate inactive GPCRs
  2. Identification of the GRK domains that determine activity and specificity for GPCRs 04/2009-08/2011

AssociateProfessorShanghai Institute of Materia Medica, Chinese Academy of Sciences
Research Projects: Drug discovery targeted GPCRs inmajor CNS diseases Major Accomplishments:

  1. Screened and evaluated the antipsychotic effect of Glycine transporter inhibitors
  2. Identification of a potent and selective serotonin 5-HT1Areceptor agonist

Membership on Editorial Boards of National and International Scientific Journals

05/2015 PresentFrontiers in Pharmacology
05/2015 PresnetFrontiers in Neuroscience
05/2015 PresentFrontiers in Psychiatry
05/2015 PresentFrontiers in Neurology
07/2015 PresentJournal of Central Nervous System Disease (Guest Editor for Supplement Project)

Professional Services

2013

Present Reviewer for Scientific Reports, Progress in Neuro-Psychopharmacology &Biological Psychiatry, Neurotoxicity Research, NeuroReport, CNS & Neurological Discorders-Drug Targets, Journal of Molecular Neuroscience, Canadian Journal of Plant Science, Chinese Pharmacological Bulletin, Neural Injury and Functional Reconstruction, 4thInternational Conference on Biomedical Engineering and Biotechnology

 

 

 

 

 

 

 

LI LINGYONG,MD

Research Scientist of Anesthesiology
MD Anderson Cancer Center Houston
USA