Wei-Chen Lee
Wei-Chen Lee
Chief, Division of Liver and Transplantation Surgery
  • :+886-3-3281200
    • :+886-3-3186823

Chang-Gung Transplantation Institute, LinKou
China

Education

1980-1987 Taipei Medical College
1989 - 1994 Surgical resident, Department of Surgery, Chang Gung Memorial Hospital
1994.7-until now Attending doctor, Department of general surgery, Chang Gung Memorial Hospital
1996.6 - 1998.5 Research fellow, Transplantation Department, UPMC, University of Pittsburgh

 

Biography

Professor Wei-Chen Lee is Professor of General Surgery, Attending Doctor and Chief of the Division of Liver and Transplantation Surgery at Chang Gung Memorial Hospital (CGMH) in Taoyuan, Taiwan. In addition, he is Head of the Chang Gung Transplantation Institute at CGMH in Linkou, Taiwan.

Professor Lee completed his medical education at Taipei Medical College and his surgical residency at CGMH. He has since remained at CGMH, becoming an Attending Doctor in the Department of Surgery in 1994. Between 1996 and 1998, he was a Research Fellow in the Department of Transplantation at the University of Pittsburgh Medical Center, PA, USA, before progressing to his current positions.

Professor Lee’s research interest lies in transplantation immunology and tumour immunology. He has been involved in over 60 research projects in Taiwan. Professor Lee speaks regularly at local and international conferences, and has published more than 130 research articles in journals such as the Annals of Surgical Oncology, British Journal of Surgery and the American Journal of Transplantation.

Professor Lee’s expertise as a transplantation surgeon in Taiwan has allowed him to actively participate in professional societies. He is an active member of the Surgical Association of the Republic of China, the American and International Society of Transplantation, and the International Society of Liver Transplantation. Furthermore, he sits on the council of the Transplantation Society of the Republic of China.

 

Research Interest

  • Transplantation immunology
  • Tumor immunology

 

Professional Activities:

1989.07-1993.06 Surgical resident, Department of general surgery,
Chang Gung Memorial Hospital.
1993.07-1994.06 Surgical chief resident, Department of general surgery,
Chang Gung Memorial Hospital.
1994.07-till now Attending doctor, Department of general surgery,
Chang Gung Memorial Hospital.
1997.07-2001.06 Assistant professor, Department of general surgery,
Chang Gung Memorial Hospital.
2001.07-2008.06 Associate professor, Department of general surgery,
Chang Gung Memorial Hospital.                                                
2008.07-till now Professor, Department of general surgery,
Chang Gung Memorial Hospital.

 

Publications

  1. Lee WC, Chen MF, Wang CS, Jan YY: Optimizing surgical treatment of non-parasitic liver cyst.  J Surg Assoc, ROC  1992;25:1325-31.
  2. Lee WC, Chen RJ, Fang JF, Wang CC, Chen HY, Chen SC, Hwang TL, Jeng LB, Jan YY,WangCS,Chen MF, Lou CC, Wang KL, Lin JN: Rupture of the diaphragm after blunt trauma. Eur J Surg 1994; 160: 479-83.
  3. Jeng LB, Lee WC, Yeh DS, Wang CC, Wang KL, Chen SC, Chen MF, Chien RN, Chiu CT, Lin DY, Liaw YF, Tan PPC, Chang CH: Immunoprophylaxis for hepatitis B virus reinfection after liver transplantation. Transplantation Proceedings 1994; 26:2243-4.
  4. Jeng LB, Lee WC, Wang CC, Wang KL, Chen SC, Chen MF, Chien RN, Chiu CT, Lin DY, Tan PPC, Chang CH: Cytomegalovirus disease in liver transplant recipients. Transplantation Proceedings 1994; 26: 2227-8.
  5. Jeng LB, HO YC, Lee WC, Wang CC, Wang KL, Chen SC, Chen MF, Lin DY, Liaw YF, Tan PPC, Chang CH: Clinical and pathologic features of hepatitis B virus reinfection after liver transplantation. Transplantation Proceedings 1994; 26:2263-4.
  6. Jeng LB, Cheng MH, Lee WC, Wang CC, Wang KL, Chen SC, Chen MF, Chien RN, Chiu CT, Lin DY, Tan PPC, Lin PJ, and Chang CH: Extracorporeal membrane oxygenation therapy for adult respiratory distress syndrome developing post liver transplantation. Transplantation Proceedings 1994; 26:2237-8.
  7. Lee WC, Chen HY, Jeng LB, Chen MF: Necrosis of the colon as a complication of cardiac surgery - case report. J Trauma 1995; 38: 979-81.
  8. Lee WC, Wang CC, Chen RJ, Fang JF, Chen MF, Lee JD: Pitfall in the management of multiple trauma in pregnancy - a case report. J Surg Assoc, ROC 1995; 28:74-8.
  9. Jeng LB, Lee WC, Wang CC, Chen MF, Hsieh TT: Hepatocellular carcinoma in a pregnant woman detected by routine screening of maternal -fetoprotein. Am J Obstet Gynecol 1995; 172:219-20.
  10. Hwang TL, Chen MF, Lee WC, Chen HM: Preservation of ampulla of vater for severe corrosive upper GI injury. Digestive Surgery 1995; 12:253-5.
  11. Fan CW, Jan YY, Lee WC, Lin PY, Chen MF: Carcinosarcoma of the gallbladder - a report of two cases. J Surg Assoc, ROC 1996; 29:174-178.
  12. Lee WC, Jeng LB, Wang CC, Chen MF, Chien RN, Chiu CT, Ling DY, Liaw YF, Chang CH: Long-term immunoprophylaxis for hepatitis B virus reinfection after liver transplantation. Transplantation Proceedings 1996; 28:1699-1700.
  13. Jeng LB, Lee WC, Chen MF, Chang CH: Cotransplantation microencapsulated hepatocytes and islets for acute hepatic failure in rats. Transplantation Proceedings 1996; 28:1859-60.
  14. Jeng LB, Lin PC, Tsai KD, Lee WC, Chen MF, Chang CH: Impaired endothelial-dependent relaxation by acetylcholine after preservation for the human hepatic artery with UW solution. Transplantation Proceedings 1996; 28:1895-6.
  15. Lee WC, Chen MF, Jeng LB, Chen TC: Unusual presentation of a small hepatocellular carcinoma: a case report. Hepato-Gastroenterology 1997; 44:153-155.
  16. Chen MF, Wang CS, Jan YY, Jeng LB, Hwang TL, Chen SC, Chao TC, Chen HM, Wang CC, Lee WC, Yeh TS and Lo YF: Results of pancreaticoduodenectomy for periampullary carcinoma and analysis of prognostic factors for survival. F. Hanyu, K. Takasaki eds “Pancreatoduodenectomy” Springer-Verlag Tokyo, 1997; 425-432.
  17. Chen MF, Jeng LB, Lee WC, Chen TC: Surgical results in patients with dual hepatitis B and C-related.  Surgery 1998; 123:554-9.
  18. Yeh CN, Hsieh CH, Hung CM, Lee WC, Jeng LB, Chen MF: Experience of using FK506 as a rescue therapy for refractory hepatic allograft rejection.  J Surg Assoc, ROC 1998; 31:52-59.
  19. Hung CF, Jeng LB, Yeh CN, Hsieh CH, Lee WC, Chen MF: Tacrolimus to rescue refractory hepatic allograft rejection- a collaborative study in Taiwan. Transplantation Proceedings 1998; 30: 3589.
  20. Lee WC, Zhong C, Qian S, Wan Y, Gauldie J, Mi Z, Robbins PD, Thomson AW, Lu AL: Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-1,2. Transplantation 1998; 66: 1810-1817.
  21. Hung CF, Jeng LB, Lee WC, Lin DY, Tan PP, Chen MF: Liver transplantation for epithelioid hemangioendothelioma. Transplantation Proceedings 1998; 30:3307-3309.
  22. Lee WC, Wan YH, Li W, Fu F, Sime PJ, Gauldie J, Thomson AW, Fung JJ., Lu L, Qian S: Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGF1. Transplantation Proceedings 1999; 31: 1195.
  23. Lu L, Lee WC, Gambotto A, Zhong C, Robbins PD, Qian S, Fung JJ, Thomson AW: Transduction of dendritic cells with adenoviral vectors encoding CTLA4-lg markedly reduces their allostimulatory activity. Transplantation Proceedings 1999; 31: 797.
  24. Chen MF, Jan YY, Jeng LB, Hwang TL, Wang CS, Chen SC, Chao TC, Chen HM, Lee WC, Yeh TS, Lo YF: Intrahepatic cholangiocarcinoma in Taiwan. J Hepatobiliary Pancreat Surg  1999; 6: 136-141.
  25. Lu L, Gambotto A, Lee WC, Qian S, Bonham CA, Robbins PD, Thomson AW: Adenoviral delivery of CTLA4lg into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients. Gene therapy 1999; 6: 554-563.
  26. Lu L, Lee WC, Takayama T, Qian S, Gambotto A, Robbins PD, Thomson AW: Genetic engineering of dendritic cells to express immunosuppressive molecules (viral IL-10, TGF-, and CTLA4lg). J Leukoc. Biol. 1999; 66: 293-296.
  27. Lee WC, Jeng LB, Chen MF: Hepatectomy for hepatitis B-, hepatitis C-, and dual hepatitis B- and C- related hepatocellular carcinoma in Taiwan. J Hepatobiliary Pancreatic Surgery; 2000;7: 265-269.
  28. Tsai HP, Lee WC, Jeng LB, Chen MF: Clinicopathologic factors influencing long term survival after resection for hepatocellular carcinoma. Chang Gung Medical Journal 2000; 23: 529-535.
  29. Wei KL, Liu NJ, Tseng JH, Lee WC, Chen TC: Inflammatory pseudotumor of the liver mimicking a malignancy: case report. Chang Gung Medical Journal 2000; 23(7):432-437.
  30. Lee WC, Qian S, Wan Y, Li W, Xing Z, Gauldie J, Fung J, Thomson AW, Lu L: Contrasting effects of myeloid dendritic cells transduced with an adenoviral vector encoding interleukin-10 on organ allograft and tumour rejection. Immunology 2000; 101(2): 233-241.
  31. Lee WC, Jeng LB, Lin PJ, Chu Y, Hung CM, Yu MC, Chiang CC: Nitric oxide donor improved the impaired endothelial-dependent relaxation of canine hepatic artery after preservation with the UW solution. Transplantation Proceedings 2000;32(7):2306-2307.
  32. Lee WC, Jeng LB, Ching YJ, Huang* CC, Chen MF: DENDRITIC CELL PROGENITORS PROLONG ALLOGRAFT SURVIVAL THROUGH TH1/TH2 PARADIGM. Transplantation Proceedings 2000;32(7):2076-2077.
  33. Yu MC, Jeng LB, Lee WC, Hung CM, Hung CF, Chiu CT, Chen MF:Giant intrahepatic hematoma after liver biopsy in a liver transplant recipient. Transplantation Proceedings 2000;32(7):2217-2218.
  34. Hung CM, Huang CC, Jeng LB, Lee WC, Yu MC, Lin CC, Shyr MH: Impaired renal function after liver transplantation: role of rhabdomyoglobinuria. Transplantation Proceedings 2000;32(7):2227-2228.
  35. Jeng LB, Lee WC, Hung CM, Yu MC, Lee CS, Chien RN, Chiu CT, Chen CC: Liver transplantation for hepatocellular carcinoma. Transplantation Proceedings 2000; 32(7): 2171-2172.
  36. Jeng LB, Lee WC, Hung CM, Lin DY, Liaw YF, Tan PC, Chen MF: Liver transplantation in Chinese patients with chronic hepatitis B. Transplantation Proceedings 2000; 32(7): 2162-2163.
  37. Hung CF, Tseng JH, Jeng LB, Lee WC, Ng KK, Wan YL: Isolated caudate lobe infarct after orthoptic liver transplantation. Transplantation Proceedings 2000;32(7):2223-2224.
  38. Lee WC, Lu# L, Chiang* YJ, Wang HC, Jeng LB, Huang** CC, Chen MF, Qian S: DONOR-DERIVED COSTIMULATORY MOLECULE-DEFICENT DENDRITIC CELLS IMPAIRED THE ALLOSTIMULATORY FUNCTION OF RECIPIENTS’ ANTIGEN-PRESENTING CELLS. Transplantation Proceedings 2001;33:273.
  39. Lee WC, Lu# L, Chiang* YJ, Jeng LB, Wang HC, Lia CR, Huang** CC, Chen MF, Qian S: IMMATURITY OF DONOR DENDRITIC CELLS REGULATED RECIPIENT T-CELLS TOWARD TH2 DEVIATION. Transplantation Proceedings 2001;33:230.
  40. Lu WT, Lee WC, Hsu BRS, Juang JH, Fu SH, Kuo CH: Effects of Virus Expressing CTLA4-IG and IL1-RA on Islet Xenografts. Transplantation Proceedings  2001; 33:713-714.
  41. Juang JH, Hsu BRS, Kuo CH, Fu SH, Lee WC, Yao NK: Neonatal Porcine Pancreas as a Source of Islet Transplantation. Transplantation Proceedings 2001;33:757-758.
  42. Lin CH, Hsieh SY, Sheen IS, Lee WC, Chen TC, Shyu WC, Liaw YF: Genome-wide Hypomethylation in Hepatocellular Carcinogenesis. Cancer Research 2001;61:4238-4243.
  43. Lee WC, Wang HC, Jeng LB, Chiang YJ, Lia CR, Huang PF, Chen MF, Qian S, Lu L: Effective treatment of small murine hepatocellular carcinoma by dendritic cells. Hepatology 2001;34:896-905.
  44. Lee WC, Jeng LB, Chen MF: Estimation of prognosis after hepatectomy for hepatocellular carcinoma. British Journal of Surgery 2002;89:311-316.
  45. Chen MF, Jeng LB, Lee WC: Surgical Results in Patients with Hepatitis Virus-related Hepatocellular Carcinoma in Taiwan. World J. Surg. 2002;26:742-747.
  46. Yeh CN, Lee WC, Jeng LB, Chen MF, Yu MC: Spontaneous tumour rupture and  prognosis in patients with hepatocellular carcinoma. Br J Surg 2002; 89(9):1125-1129.
  47. Yeh CN, Lee WC, Jeng LB, Chen MF: Hepatic resection for hepatocellular carcinoma in Taiwan. Eur J Surg Oncol 2002; 28(6):652-652.
  48. Yeh CN, Lee WC, Jeng LB, Chen MF: Pedunculated hepatocellular carcinoma: clinicopathologic study of 18 surgically resected cases. World J Surg 2002; 26(9): 1133-1138.
  49. Chuang WY, Chen TC, Hsu HL, Lee WC, Jeng LB, Huang SF: Liver cell adenoma with concomitant hepatocellular carcinoma: report of two cases. J Formos Med Assoc 2002; 101:798-802. (Case Reports)
  50. Lee WC, Chiang YJ, Wang HC, Jeng LB, Chen MF, Lu L, Qian S: FASL-Transduced Muscular Cells Induce Apoptosis of Activated T-Lymphocytes.Transplantation Proceedings 2003;35:569-570.
  51. Chen MF, Tsai HP, Jeng LB, Lee WC, Yeh CN, Yu MC, Hung CM: Prognostic Factors after Resection for Hepatocellular Carcinoma in Noncirrhotic Livers: Univariate and Multivariate Analysis. World J Surg 2003;27:443-447.
  52. Hung CM, Jeng LB, Lee WC, Yu MC, Kuo LM, Chen MF: Fulminant hepatic failure caused by hepatitis B virus activation after chemotherapy for breast cancer treated with liver transplantation: a case report. Transplant Proc. 2003;35(1):387-388.
  53. Jeng LB, Lee WC, Hung CM, Yu MC, Kuo LM, Chen MF: Liver transplantation in a patient with human immunodeficiency virus infection: a case report. Transplant Proc. 2003;35(1):361.
  54. Yeh CN, Chen MF, Lee WC, Jeng LB: Prognostic factors of hepatic resection for  hepatocellular carcinoma with cirrhosis: Univariate and multivariate analysis. J Surg  Oncol 2002; 81(4):195-202.
  55. Yeh CN, Lee WC, Chen MF, Tsay PK: Predictors of long-term disease-free survival after resection of hepatocellular carcinoma: two decades of experience at Chang Gung Memorial Hospital. Ann Surg Oncol 2003; 10(8):916-921.
  56. Yeh CN, Lee WC, Chen MF: Hepatic resection and prognosis for patients with  hepatocellular carcinoma larger than 10 cm: two decades of experience at Chang Gung Memorial Hospital. Ann Surg Oncol 2003; 10(9):1070-1076.
  57. Tsai HP, Jeng LB, Lee WC, Chen MF: Clinical Experience of Hepatic HemangiomaUndergoing Hepatic Resection. Digestive Diseases and Sciences 2003; 48:916-920.
  58. Lee WC, Chiang YJ, Wang HC, Wang MR, Lia SR, Chen MF: Functional impairment of dendritic cells caused by murine hepatocellular carcinoma. J of Clinical Immunology 2004;24:145-154.
  59. Lee WC, Yu MC, Chen MF: Prognostic Impact of Fas Ligand on hepatocellular carcinoma after hepatectomy.World J of Surgery 2004;28:792-796.
  60. Lee WC, Chen MF:Assessment of hepatic reserve for indication of hepatic resection-how I do it. J Hepato-Biliary-Pancreatic Surg 2005;12:23-26.
  61. Yeh CN, Jan YY, Lee WC, Chen MF:Hepatic resection for hepatocellular carcinoma with obstructive jaundice due to biliary tumor thrombi. World J Surg 2004;28(5):471-475.
  62. Yeh CN, Lee WC, Jeng LB, Chen MF:Hepatic resection for hepatocellular carcinoma in elderly patients. Hepato-Gastroenterology 2004;51:219-223.
  63. Lee WC, YU MC, Chiang YJ, Wang HC, Lu L, Qian S: Liver stellate cells suppress dendritic cells through IL-10.Transplantation Proceedings 2005;37:10-11.
  64. Yeh CN, Lee WC, Chen MF: Hepatic resection for hepatocellular carcinoma in end-stage renal disease patients: Two decades of experience at Chang Gung Memorial Hospital. World J Gastroenterol 2005; 11(14):2067-2071.
  65. Lee WC, Wang HC, Hung CF, Huang PF, Lia CR, Chen MF:  Vaccination of advanced hepatocellular carcinoma patients with tumor lysate-pulsed dendritic cells: a clinical trial. J of Immunotherapy 2005; 28:496-504.
  66. Chang TS, Lo SK, Shyr HY, Fang JT, Lee WC, Tai DI, Sheen IS, Lin DY, Chu CM, Liaw YF: Hepatitis C virus infection facilitates gallstone fromation. J Gastroenterology and Hepatology 2005; 20:1416-1421.
  67. Chan KM, Lee WC, Hung CF, Yu MC, Jan YY, Chen MF: Aggressive multimodality treatment for intra-hepatic recurrence of hepatocellular carcinoma following hepatic resection. Chang Gung Med J. 2005;28(8):543-550.
  68. Kuo LM, Chou HS, Chan KM, Yu MC, Lee WC*. A case of huge primary liposarcoma in the liver. World J Gastroenterol 2006; 12:1157-1159.
  69. Ulusal BG, Cheng MH, Ulusal AE, Lee WC, Wei FC. Collaboration with microsurgery prevents arterial complications and provides superior success in partial liver transplantation. Microsurgery 2006;26:490-497.
  70. Lee CF, Yu MC, Kuo LM, Chan KM, Jan YY, Chen MF, Lee WC*. Using indocyanine green test to avoid post-hepatectomy liver dysfunction. Chang Gung Med J 2007;30:333-338.
  71. Chan KM, Yu MC, Lee WC, Jan YY, Chen MF. Adenosquamous/Squamous Cell Carcinoma of the Gallbladder. J Surg Oncol 2007;95:129-134.
  72. Liu KH, Yu MC, Lee WC, Pan KT, Jen JH, Jan YY, Chen MF. Magnetic Resonance Image for Preoperative Localization of Insulinoma. Formos J Surg 2007;40:105-110.
  73. Yeh CT, Chen TC, Chang ML, Hsu CW, Yeh TS, Lee WC, Huang SF, Tsai CC. Identification of NV-F virus DNA in hepatocellular carcinoma. J Med Virol. 2007;79(1):92-96.
  74. Wu TH, Wu TJ, Tsao CK, Pan KT, Chou HS, Yu MC, Lee WC*. Disruption of Hepatic Artery Anastomosis Secondary to Perforated Duodenal Ulcer and Rescued by Right Gastric Artery in Living Donor Liver Transplantation Recipient: Report of a Case. Formos J Surg 2008;41:93-98.
  75. Wu TJ, Lee CF, Chou HS, Yu MC, Lee WC*. Suspect the donor with potential infection in the adult deceased donor liver transplantation. Transplantation Proceedings 2008;40:2486-2488.
  76. Lee CS, Liu NJ, Lee CF, Chou HS, Wu TJ, Pan KT, Chu SY, Lee WC*. Endoscopic management of biliary complications after adult right-lobe living donor liver transplantation without initial biliary decompression. Transplantation Proceedings 2008;40:2542-2545.
  77. Chiang YJ, Wang HH, Liu KL, Chu SH, Lee WC. Hepatocellular carcinoma following renal transplantation: experience in northern Taiwan.Transplant Proc. 2008;40(7):2397-2399.
  78. Su BC, Yu HP, Yang MW, Lin CC, Kao MC, Chang CH, Lee WC. Reliability of a New Ultrasonic Cardiac Output Monitor in Recipients of Living Donor Liver Transplantation. Liver transplantation 2008;14:1029-1037.
  79. Wu TH, Chou HS, Pan KT, Lee CS, Wu TJ, Chu SY, Chen MF, Lee WC*. Application of cryopreserved vein grafts as a conduit between the coronary vein and liver graft to reconstruct portal flow in adult living liver transplantation. Clin Transplant. 2009;23(5):751-755.
  80. Yeh CT, Kuo CJ, Lai MW, Chen TC, Lin CY, Yeh TS, Lee WC. CD133-positive hepatocellular carcinoma in an area endemic for hepatitis B virus infection. BMC Cancer. 2009;9:324.
  81. Chiang KC, Yeh CN, Lee WC, Jan YY, Hwang TL. Prognostic analysis of patients with pancreatic head adenocarcinoma less than 2 cm undergoing resection. World J Gastroenterol. 2009;15(34):4305-4310.
  82. Soong RS, Pan KT, Lee CF, Lee WC*. Hepatic artery-duodenal fistula with gastrointestinal bleeding after liver transplantation. Chang Gung Med J. 2009;32(5):579-583.
  83. Chan KM, Yu MC, Wu TJ, Lee CF, Chen TC, Lee WC*, Chen MF. Efficacy of surgical resection in management of isolated Extrahepatic metastases of hepatocellular carcinoma. World J Gastroenterol 2009;21:5481-5488.
  84. Chakravarty KD, Chan KM, Wu TJ, Lee CF, Lee WC*. Split-liver transplantation in 2 adults: significance of caudate lobe outflow reconstruction in left lobe recipient: case report. Transplantation Proceedings 2009;41(9):3937-3940.
  85. Liu CJ, Lee PH, Lin DY, Wu CC, Jeng LB, Lin PW, Mok KT, Lee WC, Yeh HZ, Ho MC, Yang SS, Lee CC, Yu MC, Hu RH, Peng CY, Lai KL, Chang SS, Chen PJ. Heparanase inhibitor PI-88 as adjuvant therapy for hepatocellular carcinoma after curative resection: a randomized phase II trial for safety and optimal dosage.J Hepatol. 2009;50(5):958-968.
  86. Wong CS, Lee WC, Jeng CC, Tian YC, Chang MY, Lin CY, Fang JT, Yang CW, Tsai MH, Shih HC, Chen YC. Scoring Short-Term Mortality After Liver Transplantation. Liver Transplantation 2010;16:138-146.
  87. Dahiya D, Wu TJ, Lee CF, Chan KM, Lee WC, Chen MF. Minor versus major hepatic resection for small hepatocellular carcinoma (HCC) in cirrhotic patients: A 20-year experience. Surgery 2010;147:676-685.
  88. Wu TJ, Wang F, Lin YS, Chan KM, Yu MC, Lee WC*.Right hepatectomy by the anterior method with liver hanging versus conventional approach for large hepatocellular carcinomas. British J Surg. 2010;97:1070-1078.
  89. Yeh CT, So M, Ng J, Yang HW, Chang ML, Lai MW, Chen TC, Lin CY, Yeh TS, Lee WC. Hepatitis B virus-DNA level and basal core promoter A1762T/G1764A mutation in liver tissue independently predict postoperative survival in hepatocellular carcinoma. Hepatology. 2010;52(6):1922-1933.
  90. Lee WC, Wu TJ, Chou HS, Lee CF, Chan KM, Cheng SS.Flexible and individualized treatment to achieve sustained viral response for recurrent hepatitis C in liver transplant recipients. J Viral Hepat. 2010;17:770-777.
  91. Lee WC, Lee CS, Soong RS, Lee CF, Wu TJ, Chou HS, Chan KM. Split liver transplantation in adults: Preoperative estimation of the weight of right and left hemiliver grafts.Liver Transpl. 2011;17(1):93-94.
  92. Lee WC, Chou HS, Wu TJ, Lee CS, Lee CF, Chan KM.Indicators and outcome of liver transplantation in acute liver decompensation after flares of hepatitis B. J Viral Hepat. 2011;18:193-199.
  93. Dahiya D, Lee CF, Chan KM, Wu TJ, Chou HS, Cheng SS, Lee WC. A short-term preemptive treatment for cytomegalovirus infection in seropositive patients after liver transplantation. J Hepatobiliary Pancreat Sci. 2011;18:32-38.
  94. Soong RS, Yu MC, Chan KM, Chou HS, Wu TJ, Lee CF, Wu TH, Lee WC*.Analysis of the recurrence risk factors for the patients with hepatocellular carcinoma meeting University of California San Francisco criteria after curative hepatectomy. World J Surg Oncol. 2011;27:9(1):9.
  95. Wu CC, Zarza V, Chiu CT, Lee WC, Chang PC, Hung KC, Borinaga J, Chen TH, Wen MS, Wu DL, Lin FC. Transthoracic contrast echocardiography to delect pulmonary vascular
    dilatation in liver cirrhosis caused by hepatitis virus in Taiwan. Gastroenterol J Taiwan. 2010; 27:436-443.
  96. Chan KM, Lee CS, Wu TJ, Lee CF, Chen TC, Lee WC*. Clinical perspective of acute humoral rejection after blood type-compatible liver transplantation.Transplantation. 2011;15:91(5):e29-30.
  97. Chan KM, Chou HS, Wu TJ, Lee CF, Yu MC, Lee WC*. Characterization of hepatocellular carcinoma recurrence after liver transplantation: perioperative prognostic factors, patterns, and outcome. Asian J Surg. 2011; 34(3):103-109.
  98. Frank Wang, Pan KT, Chu SY, Chan KM, Chou HS, Wu TJ, Lee WC*. Preoperative Estimation of the Liver Graft Weight in Adult Right Lobe Living Donor Liver Transplantation Using Maximal Portal Vein Diameters. LIVER TRANSPLANTATION. 2011;17:373-380.
  99. Chan KM, Yu MC, Chou HS, Wu TJ, Lee CF, Lee WC*. Significance of Tumor Necrosis for Outcome of Patients with Hepatocellular Carcinoma Receiving Locoregional Therapy Prior to Liver Transplantation. Ann Surg Oncol. 2011;18:2638-2646.
  100. Wu TH, Yu MC, Chan KM, Lee CF, Chen TC, Chang HC, Chou HS, Wu TJ, Eldeen FZ, Chen MF, Lee WC*.  Prognostic effect of steatosis on Hepatocellular carcinoma patients after liver resection. EJSO. 2011;37:618-622.
  101. Weng LC, Huang HL, Wang YW, Chang CL, Tsai CH, Lee WC. Primary caregiver stress in caring for a living-related liver transplantation recipient during the postoperative stage. Journal of Advanced Nursing 2011;67(8):1749 -1757.
  102. Huang CT, Lin HC, Chang SC, Lee WC*.  Pre-Operative Risk Factors Predict Post-Operative Respiratory Failure after Liver Transplantation. PLoS ONE. 2011;6:e22689.
  103. Wu TJ, Dahiya D, Lee CS, Lee CF, Chou HS, Chan KM, Lee WC*.Impact of portal venous hemodynamics on indices of liver function and graft regeneration after right lobe living donor liver transplantation. Liver Transplantation. 2011;17:1035 -1045.
  104. Chan KM, Chou HS, Wu TJ, Lee CF, Yu MC, Lee WC*. Characterization of Hepatocellular carcinoma recurrence after liver transplantation: Perioperative prognostic factors, patterns, and outcome. Asian Journal of Surgery. 2011; 34:128-134. (0.575)
  105. Chan KM, Chiang JM, Lee CF, Yu MC, Lee WC, Chen JS, Wang JY. Outcomes of resection for colorectal cancer hepatic metastases stratified by evolving eras of treatment. World J.Surg.Oncol. 2011 Dec;9:174.
  106. Cheng CH, Lee CF, Wu TH, Chan KM, Chou HS, Wu TJ, Yu MC, Chen TC, Lee WC*, Chen MF. Evaluation of the new AJCC staging system for resectable hepatocellular carcinoma. World J Surg Oncol. 2011;9114.
  107. Yu MC, Lee YS, Lin SE, Wu HY, Chen TC, Lee WC, Chen MF, Tsai CN. Recurrence and Poor Prognosis Following Resection of Small Hepatitis B-Related Hepatocellular Carcinoma Lesions Are Associated with Aberrant Tumor Expression Profiles of Glypican 3 and Osteopontin. Ann Surg Oncol. 2012;19:S455-S463.
  108. Wu TH, Yu MC*, Chen TC, Lee CF, Chan KM, Wu TJ, Chou HS, Lee WC, Chen MF. Encapsulation is a significant prognostic factor for better outcome in large Hepatocellular carcinoma. Journal of Surgical Oncology. 2012;105:85-90.
  109. Chan KM, Lee CF, Wu TJ, Chou HS, Yu MC, Lee WC, Chen MF. Adverse outcomes in patients with postoperative ascites after liver resection for hepatocellular carcinoma. World Journal of Surgery. 2012; 36:392-400.
  110. Ho HY, Wu TH, Yu MC, Lee WC, Chao TC, Chen MF. Surgical management of giant hepatic hemangiomas: complications and review of the literature. Chang Gung Med J. 2012;35(1):70-78.
  111. Wu TJ, Chen TC, Wang F, Chan KM, Soong RS, Chou HS, Lee WC*, Yeh CT*. Large fragment pre-s deletion and high viral load independently predict hepatitis B relapse after liver transplantation. PLoS One. 2012;7(2):e32189.
  112. Lee WC*, Wu TJ, Chou HS, Yu MC, Hsu PY, Hsu HY, Wang CC. The impact of CD4+ CD25+ T cells in the tumor microenvironment of Hepatocellular carcinoma. Surgery. 2012 ;151:213 -222.
  113. Tsai YF, Liu FC, Lin CC, Lee WC, Yu HP. Tying a Slipknot to an Intubation Stylet for Facilitating Insertion of a Nasogastric Tube in Liver Transplant Recipients: A Prospective, Randomized Study. Transplantation Proceedings. 2012; 44:438–441.
  114. Tsai YF, Su BC, Lin CC, Liu FC, Lee WC, Yu HP. Cardiac Output Derived From Arterial Pressure Waveform Analysis: Validation of the Third-Generation Software in Patients Undergoing Orthotopic Liver Transplantation. Transplantation Proceedings. 2012; 44:433–437.
  115. Tsai YF, Lin CC,  Lee WC, Yu HP. Propofol Attenuates Ischemic Reperfusion–Induced Formation of Lipid Peroxides in Liver Transplant Recipients. Transplantation Proceedings. 2012; 44:376–379.
  116. Chen LT, Chen MF, Li LA, Lee PH, Jeng LB, Lin DY, Wu CC, Mok KT, Chen CL, Lee WC, Chau GY, Chen YS, Lui WY, Hsiao CF, Whang-Peng J, Chen PJ. Long-term results of a randomized, observation-controlled, phase III trial of adjuvant interferon Alfa-2b in hepatocellular carcinoma after curative resection. Ann Surg. 2012;255(1):8-17.
  117. ElDeen FZ, Lee WC*. Hand Assisted Gauze Retractor for Right Hepatic Lobe Mobilization. Indian J Surg. 2013 Feb;75(1):50-1.
  118. Lee CF, Eldeen FZ, Chan KM, Wu TH, Soong RS, Wu TJ, Chou HS, Lee WC*. Bortezomib Is Effective to Treat Acute Humoral Rejection After Liver Transplantation. Transplantation Proceedings.2012; 44: 529–531.
  119. Cheng CH, Lee CF, Soong RS, Wu TH, Chan KM, Chou HS, Wu TJ, Yu MC, Lee WC*. Risk Factors and Clinical Outcomes of Ventilator-Associated Pneumonia in Patients on the Liver Transplant Waiting List. Transplantation Proceedings.2012; 44: 762–764.
  120. Soong RS, Chan KM, Chou HS, Wu TJ, Lee CF, Wu TH, Lee WC*. The Risk Factors for Early Infection in Adult Living Donor Liver Transplantation Recipients. Transplantation Proceedings.2012; 44: 784–786.
  121. Wang YC, Wu TJ, Wu TH, Lee CF, Chou HS, Chan KM, Lee WC*. The Risk Factors to Predict Acute Rejection in Liver Transplantation. Transplantation Proceedings.2012; 44: 526–528.
  122. Cheng CH, Yu MC, Wu TH, Lee CF, Chan KM, Chou HS, Lee WC. Surgical resection of centrally located large hepatocellular carcinoma. Chang Gung Med J. 2012;35(2):178-191.
  123. Chan KM, Eldeen FZ, Lee CF, Wu TJ, Chou HS, Wu TH, Soong RS, Lee WC*. "Left at right" adult liver transplantation: the feasibility of heterotopic implantation of left liver graft. Am J Transplant. 2012;12(6):1511-1518.
  124. Wu TJ, Wang YC, Wu TH, Lee CF, Chan KM, Lee WC*. Inhibition of allogenic T-cell cytotoxicity by hepatic stellate cell via CD4+ CD25+ Foxp3+ regulatory T cells in vitro. Transplant Proc. 2012; 44(4):1055-1059.
  125. Chan KM, Lee WC, Chen MF. The need to correct the indication for liver resection in cirrhotic patients with hepatocellular carcinoma: reply. World J Surg. 2012;36(7):1721-1722.
  126. Huang JF, Wu SM, Wu TH, Lee CF, Wu TJ, Yu MC, Chan KM, Lee WC. Liver resection for complicated hepatocellular carcinoma: Challenges but opportunity for long-term survivals. J Surg Oncol. 2012;106:959-965.
  127. Yu MC, Lee YS, Lin SE, Wu HY, Chen TC, Lee WC, Chen MF, Tsai CN. Recurrence and poor prognosis following resection of small hepatitis B-related hepatocellular carcinoma lesions are associated with aberrant tumor expression profiles of glypican 3 and osteopontin. Ann Surg Oncol. 2012;19:S455-S463.
  128. Eldeen FZ, Lee CF, Lee CS, Chan KM, Lee WC*. "Passing loop" technique: a new modification of the piggyback technique tailored to voluminous liver grafts--case report. Transplant Proc 2013; 45: 831-832.
  129. Weng LC, Chen HC, Huang HL, Wang YW, Lee WC. Change in the type of work of postoperative liver transplant patients. Transplant Proc. 2012;44(2):544-547.
  130. Weng LC, Huang HL, Wang YW, Chang CL, Tsai CH, Lee WC. The coping experience of Taiwanese male donors in living donor liver transplantation. Nurs Res. 2012; 61(2): 133-139.
  131. Lee WC, Chan KM, Chou HS, Wu TJ, Lee CF, Soong RS, Wu TH, Lee CS. Feasibility of split liver transplantation for 2 adults in the model of end-stage liver disease era. Ann Surg. 2013; 258(2):306-311.
  132. Chan KM, Fu YH, Wu TJ, Hsu PY, Lee WC. Hepatic stellate cells promote the dirrerentiation of embryonic stem cell-derived definitive endodermal cells into hepatic progenitor cells. Hepato Res. 2013; 43(6): 648-57.
  133. Wu TJ, Chan KM, Chou HS, Lee CF, Wu TH, Chen TC, Yeh CT, Lee WC. Liver transplantation in patients with hepatitis B virus-related hepatocellular carcinoma: the influence of viral characteristics on clinical outcome. Ann Surg Oncol. 2013;20(11): 3582-3590.
  134. Chan KM, Lee WC*. The Concerns of ‘‘Left at Right’’ Adult Liver Transplantation. American Journal of Transplantation 2013;13: 2777-2778.
  135. Eldeen FZ, Lee WC*. Hand assisted gauze retractor for right hepatic lobe mobilization. Indian J Surg. 2013;75(1):50-51.
  136. Lee WC. Pharmacotherapy of Small-for-Size of the Liver. Transplantation;2014
  137. Thorat A, Lee CF, Wu TH, Chan KM, Chou HS, Lee WC*. Safety of transarterial chemoembolization as bridging therapy in HCC patients with hyperbilirubinemia on the waiting list for liver transplantation: a centre experience. Hepatogastroenterology. 2013;60:2076-2079.
  138. Thorat A, Chou HS, Lee CF, Soong RS, Wu TH, Cheng CH, Wu TJ, Chan KM, Lee WC*. Effects of converting tacrolimus formulation from twice-daily to once-daily in liver transplantation recipients. BioMed Research International. 2014;2014:1-7.
  139. Lee WC, Wu TH, Cheng CH, Wu TJ, Chou HS, Chan KM.Ligation of the proximal splenic vein to overcome the effects of a large splenorenal shunt during living donor liver transplantation. Liver Transplantation. 2014;20(11):1420-1422.

 

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