Professor of Neuro-Rheumatology
University of Manchester
Anthony Jones is professor of Neuro-rheumatology at Manchester University and leads the Human Pain Research Group. He is a consultant rheumatologist at Salford Royal Foundation Trust. He has established one of the first multidisciplinary inflammatory arthritis clinics in the North West for patients with complex needs. He has also established a multidisciplinary musculoskeletal pain clinic for patients with rheumatic pain and a neuropathic pain for patients with nerve-damage related pain. In order to work more closely with healthcare professionals in primary care, the musculoskeletal and neuropathic pain clinics have recently moved to the Walkden Gateway Centre. This new facility integrates the highest standards of clinical practice with opportunities for involvement in leading-edge research.
Whilst at the Hammersmith Hospital Professor Jones pioneered the development of techniques to image neuro chemical and metabolic brain responses to pain using Positron Emission Tomography. Over the last twenty years he has used a number of functional brain imaging techniques to understand the normal and abnormal mechanisms of pain perception. There is now the exciting prospect of using some of the insights gained in these studies to develop new approaches to pharmacological and cognitive interventions for chronic pain. He also leads the International Association for the Study of Pain Musculoskeletal Pain Taskforce, and has led the development of National and International Guidelines on the Integrated Management of Musculoskeletal Pain (jointly sponsored by the BSR and the IASP).His main current goals are to use the current understanding of pain perception to encourage more rational use of current therapies and to develop new mechanisms-based treatments for pain.
Research has concentrated on the development of new techniques to identify the network of brain structures in the human brain that is involved in nociceptive processing and some of the endogenous pharmacological processes that may modify this. We were the first group to achieve these two goals. The main applications have been in musculoskeletal and post-stroke pain. Candidate mechanisms for fibromyalgia and post-stoke pain have been identified by recent PET studies
|2005||Professor of Neuro-Rheumatology||University of Manchester|
|1993||Honorary Consultant Rheumatologist||Hope Hospital|
|1995-1997||Honorary Adjunct Professor||University of Pittsburgh Imaging Centre and Dept. of Anaesthesia, Pittsburgh, Pennsylvania, USA|
|1988 - 1993||MRC Clinical Scientist||MRC Cyclotron Unit|
|Honorary Senior Lecturer||Royal Postgraduate Medical School|
|Honorary Consultant Rheumatologist||Hammersmith Hospital|
|Honorary Consultant Rheumatologist||St Bartholomew's Hospital|
|1986 - 1988||Senior Registrar||Rheumatology and General Medicine, St Bartholomew's Hospital and Whipp's Cross Hospital, London|
|1985 - 1986||MRC Clinical Scientist||MRC Cyclotron Unit on secondment to Service Hospitalier Frederic-Joliot (Commissariat a l'Energie Atomique) Orsay, Paris, France|
|Hon Senior Registrar||Dept of Rheumatology, St Bartholomew's Hospital|
|1984 - 1985||Research Fellow||MRC Cyclotron Unit: Hammersmith Hospital|
|Honorary Registrar||Rheumatology, St Bartholomew's Hospital|
|1983 - 1984||Registrar||General Medicine and Diabetology Professorial Medical Unit, Hackney Hospital|
|1982 - 1983||Registrar||General Medicine and Gastroenterology: Hackney Hospital|
|1981 - 1982||Senior House Officer||Oncology Royal Free Hospital (Dr Boessen|
|1980 - 1981||Senior House Officer||General Medicine and Cardiology, Royal Free Hospital|
|1980||Senior House Officer||Renal Medicine, Guy's Hospital (Prof Cameron|
|1980||Senior House Officer||General and Thoracic Medicine, Chest Unit, New Cross Hospital|
|1979 -1980||Senior House Officer||Neurology: St. Mary's Hospital, London|
|1979||House Officer||Medicine, Lewisham Hospital, London|
|1978 – 1979||House Officer||Surgery, Guy's Hospital, London|
- Hughes M, Akram Q, Rees David C, Jones AKP. (2016). Haemoglobinopathies and the Rheumatologist. Rheumatology (Oxford)
- AKP Jones, C Brown. (2015). How Chronic Pain May Change Your Brain. Time Magazine,
- Brown CA, Huneke N, Jones AKP. (2015). Pain Syndromes. In Arthur W Toga (Ed.), Brain Mapping. ( 3, pp. 1135-1141). Elsevier.
- Pippa Tyrrell, Anthony Jones. (2015). Post-stroke pain. Management of post-stroke pain complications. Springer.
- Matt Leung, Michael Hughes, Jayde Lane, Subhasis Basu, Kate Ryan, Anthony KP Jones. (2015). Severe Disability in a Patient With Rheumatoid Arthritis and Sickle Cell Anemia An Underreported, But Yet a Potentially Treatable Combination of Diseases. journal of clinical rheumatology, 21(8), 458-459.
- E Swannell, AKP Jones, R Brown, C Brown. (2015). Some words hurt more than others: Semantic activation of pain concepts in memory and subsequent experiences of pain. Pain,
- Brown CA, Matthews J, Fairclough M, McMahon A, Barnett E, Al-Kaysi A, El-Deredy W, Jones AK. (2015). Striatal opioid receptor availability is related to acute and chronic pain perception in arthritis: does opioid adaptation increase resilience to chronic pain? Pain,
- Jones AKP, Brown CA. (2014). Could Buddhism help treat ARTHRITIS? Worrying about illnesses makes them worse because 'most pain is in the mind'.
- Jones AKP, Brown CA. (2014). Mind power could help patients with pain. Manchester Evening News,
- Jones AKP, Brown CA. (2014). New way to fight agony of arthritis: Positive thinking could be the answer. Daily Express, 1.
- Fairclough M, Prenant C, Brown G, McMahon A, Lowe J, Jones AKP. (2014). The automated radiosynthesis and purification of the opioid receptor antagonist, [6-O-methyl-11C]diprenorphine on the GE TRACERlab FXFE radiochemistry module. Journal of Labelled Compounds and Radiopharmaceuticals, 57(5), 388-396.
- Brown CA, El-Deredy W, Jones AKP. (2014). When the brain expects pain: common neural responses to pain anticipation are related to clinical pain and distress. E J N, 39(4), 663-672.
- Huneke N, Burford E, Brown CA, Trujillo-Baretto N, Watson A, El-Deredy W, Jones AKP. (2013). Experimental placebo analgesia changes resting-state alpha oscillations. P L o S Medicine (Online), 8(10), 1-11.
- Jones AKP, Brown CA. (2013). Post-stroke shoulder pain: nociceptive or neuropathic? Pain, 154(2), 189.
- Brown CA, Jones AKP. Anticipatory and pain-evoked neural correlates of pain symptoms, mood and coping in patients with fibromyalgia and osteoarthritis. Presented at IASP 2012. Milan.
- Huneke N, Burford E, Watson A, El-Deredy W, Jones AKP. Increased Ongoing EEG alpha power is associated with pain relief in an experimental placebo procedure. Presented at IASP 2012. Milan.
- Jones AKP. (2012). New study warns cases of gout on the rise. The Independent,
- Watson A, Power A, Brown CA, El-Deredy W, Jones A. (2012). Placebo analgesia - cognitive influences on therapeutic outcome. Arthritis Research and Therapy, 14, 206.
- Almarzouki A, Brown CA, Brown R, Jones AKP. Prior negative expectations reduce the pain alleviating effects of positive expectancy cues: an experimental pain study in healthy participants. Presented at IASP 2012. Milan.
- Brown CA, Jones AKP. (2012). Psychobiological correlates of improved mental health in patients with musculoskeletal pain after a mindfulness-based pain management program.Clinical Journal of Pain,
- Watson A, Power A, Lenton A, Rainey T, Rankin J, El-Deredy W, Jones AKP. Reproducibility of Experimental Placebo Analgesia in Chronic Pain. Presented at IASP 2012. Milan.
- Jones AKP, Huneke N, Lloyd D, Brown CA, Watson A. (2012). Role of functional brain imaging in understanding rheumatic pain. CURRENT RHEUMATOLOGY REPORTS,
- Brown CA, Jones AKP. (2011). Its time for your meditation. The Independent,
- Brown C, Watson A, Morton D, Power A, El-Deredy W, Jones AKP. (2011). Role of the central neurophysiological systems in placebo analgesia and their relationship to cognitive processes mediating placebo responding. Future Neurology, 6(3), 389-398.
- Watson A, Power A, Lenton A, El-Deredy W, Morais S, Jones AKP. (2010). A behavioural and electrophysiological study of distraction and attention to a painful laser stimulus in fibromyalgia, arthritis and healthy volunteers. Presented at IASP 2010. MONTREAL.
- El-Deredy W, Trujillo-Barreto NJ, Watson A, Jones AKP. (2010). Bayesian model comparison of placebo analgesia: parameterisation of prior information and expection. Presented at IASP 2010. Montreal.
- Morton DL, Brown CA, Watson A, El-Deredy W, Jones AKP. (2010). Cognitive changes as a result of a single exposure to placebo. Neuropsychologia,
- Brown C, Jones AKP. (2010). Cortical Interactions between pain-related anxiety and selective attention to pain. Presented at IASP 2010. MONTREAL.
- Brown C, Jones AKP. (2010). Differences between patients with osteoarthritis and fibromyalgia in their anticipation of future pain events: a behavioural and EEG study. Presented at IASP 2010. MONTREAL.
- Brown A, Jones AKP. (2010). Meditation experience predicts less negative appraisal of pain: Electrophysiological evidence for the involvement of anticipatory neural responses. Pain, 150(3), 428.
- Jones AKP, Brown CA. (2010). Meditation reduces the emotional impact of pain making it easier to bear. Daily Mail,
- Morton D, El-Deredy W, Morton A, Elliott R, Jones AKP. (2010). Optimism facilitates the utilization of prior cues. European Journal of Personality,
- Morton D, El-Deredy W, Watson A, Jones AKP. (2010). Placebo Analgesia as a case of a cognitive style driven by prior expectation. Brain Research, 1359, 137-141.
- McMunn V, Bedwell C, Neilson J, Jones AKP, Dowswell T, Lavender T. (2009). A national survery of the use of TENS in labour. British Journal of Midwifery, 17(8), 492-495.
- Watson A, Morais S, Bentley D, Boger E, Boyle Y, Kulkarni B, Jones AKP. (2009). Behavioural study of distraction and attention to a painful laser stimulus in fibromyalgia, arthritis and healthy volunteers. Presented at BSR Conference 2009.
- Brown C, Jones AKP. (2009). Experimental modification of expectations and beliefs about pain in patients with fibromyalgia and healthy controls. Presented at BSR 2009.
- -Ray M, Tom BDM, Morais S, Watson A, Bentley D, Boyle Y, Jones AKP. (2009). Identifying fibromyalgia and osteoarthritis patients subgroups at most risk of psychological distress. Presented at The British Pain Society Annual Scientific Meeting 2009.
- Watson A, El-Deredy W, Iannetti G I, Lloyd D, Tracey I, Vogt B A, Nadeau V, Jones AKP. (2009). Placebo conditioning and placebo analgesia modulate a common brain network during pain anticipation and perception. Pain, 145(1-2), 24-30.
- Morton D, Watson A, El-Deredy W, Jones AKP. (2009). Reproducibility of placebo analgesia: Effect of dispositional optimism. PAIN, 146(1-2), 194-198.
- Morton D, Watson A, El-Deredy W, Jones AKP. (2009). The reproducibility of placebo analgesia. Presented at BSR 2009.
- Brown CA, Jones AKP. (2008). A role for midcingulate cortex in the interruptive effects of pain anticipation on attention. Clinical Neurophysiology, 119(10), 2370-9.
- Brown CCA, Seymour B, El-Deredy W, Jones AK P. (2008). Confidence in beliefs about pain predicts expectancy effects on pain perception and anticipatory processing in right anterior insula. Pain, 139(2), 324.
- JA Clark, Brown CA, Jones AKP. (2008). Dissociating nociceptive modulation by the duration of pain anticipation from unpredictability in the timing of pain. Clinical Neurophysiology, 119(12), 2870-8.
- Jones AKP. (2008). Is Pain All in The Brain. Manchester Evening News,
- Christopher A. Brown, Ben Seymour, Yvonne Boyle, Wael El-Deredy, Anthony K.P. Jones. (2008). Modulation of pain ratings by expectation and uncertainty: Behavioral characteristics and anticipatory neural correlates. Pain, 135(3), 240-250. Jones AKP. (2008). New research to harness the power of placebo effect. Arthritis Today,
- Boyle Y, El-Deredy W, Martínez Montes E, Bentley DE, Jones AK P. (2008). Selective modulation of nociceptive processing due to noise distraction. Pain, 138( 3),
- Jones AK P, Watson A. (2007). A functional imaging of pain: A cortical model of allodynia in poststroke pain and fibromyalgia.
- Bhavna Kulkarni, D E Bentley, Elliott R, PJ Julyan, E Boger, A Watson, Y Boyle, El-Deredy W, Jones AK P. (2007). Arthritic pain is processed in brain areas concernedwith emotions and fear. Arthritis and Rheumatism, 56 (4), 1345-1354.
- Zampini M, El-Deredy W, Bentley DE, Vogt B, Jones AK P, Spence C. (2007). Attention speeds the perceptual processing of painful stimuli. Behavioral Brain Research, 414, 75 - 79.
- Jones AKP. (2007). New insights into managing musculoskeltal pain. MD Conference Express,
- Porro C, Martinig M, Facchin P, Maieron M, Jones AK P, Luciano F. (2007). Parietal cortex involvement in the localisation of tactile and noxious mechanical stimuli: A transcranial magnetic stimulation study. Behavioural Brain Research, 178, 183-189. Watson A, El-Deredy W, Vogt BA, Jones AK P. (2007). Placebo analgesia is not due to compliance or habituation: EEG and behavioural evidence. NeuroReport, 18, 771-775.
- Langley G, Evans T, Holgate S, Jones AK P. (2007). Replacing animal experiments: choices, chances and challenges. Bioessays, 918-926.
- Langley G, Evans T, Holgate ST, Jones AKP. (2007). Replacing animal experiments: choices, chances and challenges. Bioessays,
- Jones AKP. (2006). A new approach to pain. Arthritis Today,
- Boyle Y, Bentley DE, Watson A, Jones AK P. (2006). Acoustic noise in functional magnetic resonance imaging reduces pain unpleasantness ratings. Neuroimage, 31, 1278-1283.
- Watson A, El-Deredy W, Bentley DE, Brent A Vogt, Jones AK P. (2006). Categories of placebo response in the absence of site-specific expectation of analgesia. Pain, 126, 115-122.
- Jones AKP, Georgiou G. (2006). Probing Pain. Biological Science Review - Philip Allan Updates,
- Bentley DE, Baumgartner U, Watson A, G Barrett, Kulkarni B, Youell P, Schlereth T, Jones AK P, R Detlef-Treede. (2006). The time-course of sensory and affective pain processing: evidence from laser-evoked potentials.
- Nadeau VJ, A Abraham, Watson A, Bentley DE, Boyle Y, Jones AK P. (2005). Ability to localise a heat stimulus is dependent on stimulus intensity.
- Kulkarni B, Bentley D, Elliott R, Youell P, Watson A, Derbyshire S, Frackowiak R, Friston K, Jones AK P. (2005). Attention to pain localization and unpleasantness discriminates the functions of the medial and lateral pain systems. Eur J Neurosci, 21( 11), 3133-42.
- Nadeau VJ, AD Abraham, Watson A, Bentley DE, Jones AK P. (2005). Does the intensity of a painful heat stimulus affect the ability to localize it?.
- Bentley DE, Ulf Baumgartner, Watson A, Geoff Barrett, Kulkarni B, Youell P, Jones AK P. (2005). Early involvement of right operculo-insular cortex cortex in processing pain unpleasantness : evidence from laser evoked potentials. Brain Topography. ( 17(3), ).
- El-Deredy W, Boyle Y, Bentley DE, Jones AK P. (2005). Modulation of laser evoked potentials frequency response to pain localisation, affect and distraction.
- N Trujilli-Barreto, Boyle Y, El-Deredy W, Bentley DE, Jones AK P. (2005). Modulation of medial and lateral pain systems by noise distraction.
- Boyle Y, Bentley DE, Watson A, Jones AK P. (2005). Modulation of pain affect, spatial discrimination and laser evoked potentials by distraction.
- Watson A, Jones AK P, Bentley DE, Brent Vogt, Carlo Porro. (2005). Placebo-induced reduction of pain intensity and unpleasantness ratings of a laser stimulus. B
- Watson A, El-Deredy W, Bentley DE, Boyle Y, Brent Vogt, Jones AK P. (2005). Placebo-induced reductions in pain ratings & laser evoked potentials. Poster 11th World congress on Pain IASP, Sydney 2005.
- Boyle Y, Bentley DE, Watson A, Jones AK P. (2005). The differential effects of distraction from pain localisation versus pain unpleasantness on laser-evoked potentials.
- Chris Brown, Bentley DE, Boyle Y, Watson A, Kulkarni B, Emma Boger, Jones AK P. (2005). The expectancy of pain in fibromyalgia, osteoarthritis & healthy volunteers.
- Chris Brown, Boyle Y, Watson A, Bentley DE, Jones AK P. (2005). The expectancy of pain: Modulation by intensity and uncertainty.
- Jones AK P. (2005). The role of the cerebral cortex in pain perception. Proceedings of the 11th World Congress on Pain, IASP, Sydney, Australia 2005.
- Bentley DE, Alison Watson, Rolf-Detleff Treede, Geoff Barrett, Youell P, Kulkarni B, Jones AK P. (2004). Differential effects on the Laser Evoked Potential of Selectively Attending to Pain Localisation versus Pain Unpleasantness. Clinical Neurophysiology, 115, 1846 - 1856.
- T N Hoang, El-Deredy W, Bentley DE, Jones AK P, P J Lisboa, Francis P McGlone. (2004). Dipole source localisation using independent component analysis: Single trial localisation of laser evoked pain.
- Youell P, Richard G Wise, Bentley DE, Mark D Dickinson, King T, Irene Tracey, Jones AK P. (2004). Lateralisation of nociceptive processing in the human brain: a functional magnetic resonance imaging study. Neuroimage,
- Youell P, Wise R, Bentley D, Dickinson M, King T, Tracey I, Jones AK P. (2004). Lateralisation of nociceptive processing in the human brain: a functional magnetic resonance imaging study.Neuroimage, 23( 3), 1068-77.
- Bentley DE, Stuart W G Derbyshire, Youell P, Jones AK P. (2003). Caudal cingulate cortex involvement in pain processing: An inter-individual laser evoked potential source localisation study using realistic head models. Pain, 102:3, 265-271.
- Bentley DE, Youell P, Jones AK P. (2002). Anatomical localisation and intra-subject reproducibility of laser evoked potential source in cingulate cortex, using a realistic head model. Clin Neurophysiol, 113, 1351-1356.
- Derbyshire SWG, Jones AK P, Creed FH, Starz T, Meltzer CC, Townsend DW, Peterson AM, Firestone L. (2002). Cerebral responses to noxious thermal stimulation in chronic low back pain patients and normal controls. Neuroimage, 16(1), 158-168.
- Lampros Stergioulas, M Reoullas, Costas S Xydeas, E Baltas, Bentley DE, Youell P, Jones AK P. (2002). Coherence pattern classification using LVQs for pain detection.
- Kulkarni B, Jones AK P, Elliott R, Bentley DE, Stuart Derbyshire, Youell P. (2002). Cortical processing of affective versus sensory-discriminative aspects of pain - a PET study.
- Spence C, Bentley DE, Phillips N, McGlone FP, Jones AK P. (2002). Selective attention to pain: a psychophysical investigation. Exp Brain Res, 145, 395-402.
- Bentley DE, Jones AK P. (2001). Consistent localisation of hig-density pain evoked potential recordings in cingulate cortex, using realistic head models.
- Bentley DE, Youell P, Crossman AA.R, Jones AK P. (2001). Source localisation of 62-electrode human laser pain evoked potential data using a realistic head model. Int J Psychophysiol, 41/2, 187-193.
- Bentley DE, Youell P, Crossman AA.R, Jones AK P. (2000). Evidence for a movement suppression component of human pain evoked potentials.
- Bentley DE, Youell P, Crossman AA.R, Jones AK P. (2000). Pain evoked potentials: possible evidence for a movement suppression component? 3rd Congress of the European Federation of IASP Chapters, Nice, France,
- Youell P, Bentley DE, King TA, Jones AK P. (2000). manipulation of the affective components of the pain experience using laser stimulation. Eur. J. Neuro, 12(11),
- Bentley DE, Youell P, Carson KI, Crossman AA.R, Jones AK P. (1999). Spatial and temporal localisation of pain processing in the human brain.
- Youell P, Bentley DE, Clark S, Dickinson MR, King TA, Jones AK P. (1999). laser pain stimulation.