Education

Experience

Biography

Ge Wang is currently the Clark & Crossan Endowed Chair Professor and the Director of the Biomedical Imaging Center, Rensselaer Polytechnic Institute, Troy, NY, USA. He authored the pioneering paper on the first spiral/helical cone-beam computed tomography (CT) algorithm in 1991. Spiral/helical cone-beam/multi-slice CT is constantly used in almost all hospitals worldwide. There are over 100 million CT scans yearly with a majority in the spiral/helical cone-beam/multi-slice mode. He and his collaborators published the first paper on bioluminescence tomography, creating a new area of optical molecular tomography. His group published the first papers on interior tomography and omni-tomography for grand fusion of all relevant tomographic modalities (“all-in-one”) to acquire different datasets simultaneously (“all-at-once”) with simultaneous CT-MRI as an example. His results were featured in Nature, Science, and PNAS, and recognized with academic awards. He wrote over 420 journal papers, receiving a high number of citations. His team has been in collaboration with world-class groups, and continuously well-funded by federal agencies. His interest includes x-ray CT, optical molecular tomography, multimodality imaging, bibliometrics, and deep learning. He is the Lead Guest Editor of the four IEEE Transactions on Medical Imaging Special Issues on cone-beam CT, molecular imaging, compressed sensing, and spectral CT respectively, the founding Editor-in-Chief of the International Journal of Biomedical Imaging, and an Associate Editor of the IEEE Transactions on Medical Imaging, IEEE Access, Medical Physics, and Journal of X-ray Science and Technology. He is a fellow of the SPIE, OSA, AIMBE, AAPM, and AAAS.

Research Interest

• Cone-beam Spiral CT
• Fan-beam Spiral CT
• Interior Tomography & Omni-Tomography
• Bioluminescence Tomography
• Luminescence Tomography
• Informetrics
• Applied mathematics
• Multimodality imaging

Scientific Activities

Honors & Awards

• 1988 Oxford Univ. PhD Scholarship for the Sino-UK PhD Program (Robotics)
• 1988 Univ. Postgraduate Research Scholarship (Remote Sensing). Univ. of Tasmania, Australia
• 1990 Travel Award. International Symposium on X-ray Microscopy, London, UK
• 1992 Travel Award. Scanning 1992, Atlantic City, NJ
• 1993 Travel Award. Scanning 1993, Orlando, FL
• 1999 Marquis Who's Who in Science and Engineering (00-01)
• Outstanding Scientists of the 21st Century (2001), International Biographical Centre, Cambridge CB2 3QP, England
• Samuel Reynolds Pritchard Professor of Engineering, VT-WFU School of Biomedical Engineering & Sciences, Virginia Polytechnic Institute & State University, 06-13
• Distinguished Associate Editor Service for Journal of Medical Physics, American Association of Physicists in Medicine, presented on November 26, 2007
• Associate Editor of the month for the IEEE Access Special Section: Emerging Computed Tomography Technologies, 2015
• Dean’s Award for Excellence in Research, College of Engineering, Virginia Tech, 2010
• Distinguished Leading Research Award (DLR Award), Virginia Tech – Wake Forest University School of Biomedical Engineering and Sciences, 2010
• Clark & Crossan Endowed Chair Professor, Rensselaer Polytechnic Institute, 13-Now
• Certificate of Merit for ISBI’14 General Chair, IEEE EMBS & SPS, 2014
• Outstanding Associate Editor, IEEE TMI (the prime journal in the medical imaging field), 2015 (leading guest editors for 4 special issues; managed 57 manuscripts over the past 2 years with an average turn-around time of 28.75 days).

Publications

1. Chen H, Zhang Y, Zhang WH, Liao PX, Li K, Zhou J, Wang G: Low-dose CT via convolutional neural network. Biomedical Optics Express 8:679-694, http://dx.doi.org/10.1364/BOE.8.000679, 2017.
2. Chen MY, Wei B, Wang G: General rigid motion correction for CT imaging based on locally linear embedding. Pending review, 2017.
3. Han WM, Long FX, Cong WX, Intes X, Wang G: Radiative transfer with delta-Eddington-type phase functions. Applied Mathematics and Computation 300:70-78, 2017.
4. Ge G, Zhang J, Lumby C, Winkler M, Cong WX, Wang G: Interior tomography with dual-source data. Pending review, Academic Radiology, 2016.
5. Xi Y, Cong WX, Harrison D, Wang G: Grating oriented line-wise filtration (GOLF) for dual-energy CT. Pending review, PMB, 2016.
6. Yang JS, Yu HY, Wang G: Initial analysis of the middle problem. Journal of X-ray Science and Tech. pending revision, 2017.
7. Cong WX, Lai YR, Yang QS, Li Jia, Wang G: CT image reconstruction in a low dimensional manifold. Pending, 2016.
8. Oh O, Wang G, Lee SW: K-edge-based interior tomography. Pending review, 2016.
9. Zhang YB, Mou XQ, Wang G, Yu HY: Tensor-based dictionary learning for spectral CT. IEEE Trans. Medical Imaging 36:142-154, 2017.
10. Wang YM, Wang G, Mao SW, Cong WX, Ji ZL, Cai JF, Ye JB: A framelet-based iterative maximum-likelihood reconstruction algorithm for spectral CT. Inverse Problems 32: doi:10.1088/0266-5611/32/11/115021, 2016.
11. Wang YM, Wang G, Mao SW, Cong WX, Ji ZL, Cai JF, Ye JB: A spectral interior CT by a framelet-based reconstruction algorithm. Journal of X-ray Sci. & Tech. 24:771-785, 2016.
12. Puliyakote ASK, Vasilescu DM, Sharma KS, Wang G, Hoffman EA: A skeleton-tree based approach to acinar morphometric analysis using micro computed tomography with comparison of acini in young and senile C57Bl/6 mice. Journal of Applied Physiology, DOI: 10.1152/japplphysiol.00923.2015, 2016.
13. Puliyakote ASK, Vasilescu DM,  Newell Jr. JD, Wang G, Weibel ER, Hoffman EA:  Morphometric differences between central vs. surface acini in A/J mice using high–resolution micro computed tomography. Journal of Applied Physiology, DOI: 10.1152/japplphysiol.00317, 2016.
14. Li L, Wang BG, Wang G: Edge-oriented dual-dictionary guided enrichment (EDGE) for MRI-CT Image Reconstruction. Journal of X-ray Science and Technology 24:161-175, 2016.
15. Xi Y, Jin YN, De Man B, Wang G: High-kVp assisted metal artifact reduction for x-ray computed tomography. IEEE Access, DOI 10.1109/ACCESS.2016.2602854, 2016.
16. Pang S, Zhu ZY, Wang G, Cong WX: Small-angle scatter tomography with a photon-counting detector array. Phys. Med. Biol. 61:3734-3748, 2016.
17. Li J, Miao C, Shen Z, Wang G, Yu H: Robust frame based x-ray CT reconstruction. Journal of Computational Mathematics 34:683-704, 2016.
18. De Man R, Wang G, Kalra M, Otrakji A, Hsieh S, Pelc N: Upper-bound on CT dose reduction for nodule detection. IEEE Access 4: Digital Object Identifier 10.1109/ACCESS.2016.2592941, 2016.
19. Chen MY, Xi Y, Cong WX, Wei B, Wang G: CT imaging geometrical calibration via locally linear embedding. Journal of X-ray Science & Tech 24:241–256, 2016.
20. Getzin M, Gjesteby L, Chuang YJ, McCallum S, Cong WX, Pan ZW, Dai GH, Zhang SB, Wang G: Exploring the modulation of magnetic resonance relaxation parameters through the use of high energy electromagnetic radiation and semiconducting nanoparticles. JSM Biomedical Imaging 3:1005, 2016.
21. Gong H, Yang H, Jia X, Wang G, Cao GH: X-ray scatter correction for multi-source interior computed tomography. Med. Phys., DOI: 10.1002/mp.12022, 2016.
22. Wang G: A perspective of deep imaging. IEEE Access, 10.1109/ACCESS.2016.2624938, 2016.
23. Gjesteby L, De Man B, Jin YN, Paganetti H, Verburg J, Giantsoudi D, Wang G: Metal Artifact Reduction in CT: Where Are We After Four Decades? IEEE Access 4, DOI 10.1109/ACCESS.2016.2608621, 2016.
24. Yang QS, Cong WX, Xi Y, Wang G: Spectral x-ray CT image reconstruction with a combination of energy-integrating             and                photon-counting  detectors. PLoS One,  http://dx.doi.org/10.1371/journal.pone.0155374, 2016.
25. Giantsoudi D, De Man B, Verburg J, Trofimov A, Jin YN, Wang G, Gjesteby L, Paganetti H: Metal artifacts in computed tomography for radiation therapy planning: dosimetric effects and impact of metal artifact reduction. Accepted by Phys. Med. Biol., 2016.
26. Yang QS, Cong W, Wang G: Superiorization-based multi-energy CT image reconstruction. Accepted by Inverse Problems, 2016.
27. Wang G, Kalra M, Murugan V, Xi Y, Gjesteby L, Getzin M, Yang QS, Cong WX, Vannier MW: Simultaneous CT-MRI: Next chapter of multi-modality imaging. Med. Phys. 42:5879-5889, 2015.
28. Wang G, Butler A, Yu HY, Campbell M: Spectral CT with photon-counting detectors – The next wave of the CT field. The editorial for the special issue on spectral CT, IEEE Trans. Medical Imaging 34:693-696, 2015.
29. Yu HY, Mou XQ, Wang G: Editorial: Emerging Computed Tomography Technologies. The editorial for special issue on emerging CT technologies, IEEE Access 2:10.1109/ACCESS.2014.2384851, 2015.
30. Li L, Chen ZQ, Cong WX, Wang G: Spectral CT imaging with hybrid detectors in dynamic-threshold counting and integrating modes. IEEE Trans. Medical Imaging 34:716-728, 2015.
31. Meng B, Cong WX, De Man B, Wang G: Energy window optimization for x-ray K-edge tomographic imaging. IEEE Trans. Biomedical Engineering 63:1623-1630, 2015.
32. Zhang Y, Xi Y, Yang QS, Cong WX, Zhou J, Wang G: Spectral CT reconstruction with image sparsity and spectral means. IEEE Trans. Computational Imaging 2:510-523, 2016.
33. Yu H, Wang G, Yang JS, Pack J, Jiang M, DeMan B: Data consistency condition for truncated projections in fan-beam geometry. Journal of X-ray Science & Tech. 23:627-638, 2015.
34. Yang QS, Lv Y, Xi Y, Kalra M, Cong WX, Wang G: Sinogram-based attenuation correction in PET/CT. Journal of X-ray Science and Technology 24:9-22, 2016.
35. FitzGerald P, Bennett J, Carr J, Edic P, Entrikin D, Gao H, Iatrou M, Jin Y, Liu BD, Wang G, Wang J, Yin YN, Yu HY, Zeng Z, De Man B: Cardiac CT: a System Architecture Study. Journal of X-ray Science and Tech. 24:43-65, 2016.
36. Xi Y, Zhao J, Bennett J, Sinusas A, Wang G: Simultaneous CT-MRI image reconstruction with structural coupling and compressive sensing. IEEE Trans. Medical Imaging 63:1301-1309, 2015.
37. Yang QS, Kalra M, Padole A, Li J, Hilliard E, Lai YJ, Wang G: Big data from CT scanning. JSM Biomedical Imaging Data Papers 2(1):1003 (6 pages), 2015.
38. Cong WX, Xi Y, Wang G: Spherical grating based x-ray Talbot interferometry. Medical Physics 42:6514-6519, 2015.
39. Tan SQ, Zhang, YB, Wang G, Mou XQ, Cao GH, Wu ZF, Yu HY: Tensor-based dictionary learning for dynamic tomographic reconstruction. Phys. Med. Biol. 60: 2803-2818, 2015.
40. Yang FG, Ozturk MS, Zhao LL, Cong WX, Wang G, Intes X: High-resolution mesoscopic fluorescence molecular tomography based on compressive sensing. IEEE Trans. BME 62:248-255, 2015.
41. Stefanov P, Cong WX, Wang G: Modulated luminescence tomography. Inverse Problems and Imaging 9:579-589, 2015.
42. Liu BD, Yu H, Verbridge S, Sun L, Wang G: Dictionary learning based reconstruction method for electron tomography, Scanning 36:377-383, 2014.
43. Bennett J, Opie AMT, Xu Q, Yu HY, Walsh M, Butler A, Butler P, Cao GH, Mohs A, Wang G: Hybrid spectral micro-CT: System design, implementation & preliminary results. IEEE Trans. Biomedical Engineering 61:246-253, 2014.
44. Liu F, Yu H, Cong WX, Wang G: Top-level design and pilot analysis of low-end CT scanners based on linear scanning for developing countries. Journal of X-ray Science and Technology 22:673-686, 2014.
45. Opie AMT, Bennett J, Walsh M, Rajendran K, Yu HY, Xu Q, Butler A, Butler P, Cao GH, Mohs A, Wang G: Study of scan protocol for exposure reduction in hybrid spectral micro-CT. Scanning 36:444-455, 2014.
46. Zhang SL, Zhang DH, Gong H, Ghasemalizadeh O, Wang G, Cao GH: Fast and accurate computation of system matrix for area integral model based ART. Optical Engineering 53:113101, doi: 10.1117/1.OE.53.11.113101, 2014.
47. Liu FL, Yang QS, Cong WX, Wang G: Dynamic bowtie filter for multi-slice/cone-beam CT. PLoS ONE 9(7):e103054, doi:10.1371/journal.pone.0103054, 2014.
48. Li L, Chen ZQ, Wang G, Chu JS, Gao H: A tensor PRISM algorithm for multi-energy CT reconstruction and comparative studies. Journal of X-ray Science and Technology 22:147-163, 2014.
49. Yu HY, Wang G: SART-type half-threshold filtering approach for CT reconstruction. IEEE Access 2:doi:10.1109/ACCESS.2014.2326165, 2014.
50. Cao G,  Liu BD, Gong H,  Yu H, Wang G: A stationary-sources and rotating-detectors computed tomography architecture for higher temporal resolution and lower radiation dose. IEEE Access 2:doi:0.1109/ACCESS.2014.2363367, 2014.
51. Yelleswarapu VR, Liu FL, Cong WX, Wang G: Top-level system designs for hybrid low-field MRI-CT with potential of pulmonary imaging. Sensing and Imaging 15:98, DOI 10.1007/s11220-014-0098-4, 2014.
52. Neculaes B, Edic P, Frontera M, Caiafa A, Wang G, De Man B: Promise of distributed sources – CT and beyond: lessons learned and future outlook. IEEE Access 2: DOI 10.1109/ACCESS.2014.2363949, 2014.
53. Lv Y, Zhao J, Wang G: Edge-guided dual-modality image reconstruction. IEEE Access 2:10.1109/ACCESS.2014.2371994, 2014.
54. Sharma KS, Gong H, Ghasemalizadeh O, Yu HY, Wang G, Cao GH: Interior micro-CT with an offset detector. Med. Phys. 41:061915(1-10), 2014.
55. Ren S, Chen X, Wang H, Qu X, Wang G, Liang JM, Tian J: Molecular Optical Simulation Environment (MOSE): A platform for the simulation of light propagation in turbid media. PLoS ONE 8(4):e61304. doi:10.1371/journal.pone.0061304, 2013.
56. Feng P, Cong WX, Wei B, Wang G: Analytic comparison between x-ray fluorescence CT and K-edge CT. IEEE Trans. Biomedical Engineering 61:975-985, 2014.
57. Ren, Wu, Wang G, Wu XZ, Liu H: Three-dimensional x-ray fluorescence mapping (XFM) of a gold nanoparticle-loaded phantom. Med. Phys. 41:031902:1-12, 2014.
58. Cong WX, Liu FL, Wang C, Wang G: X-ray micro-modulated luminescence tomography (XMLT). Optics Express 22:5572–5580, 2014 (selected by the Editors, Andrew Dunn and Anthony Durkin, for publication in the Virtual Journal for Biomedical Optics (VJBO) V9(5), April 29, 2014, which is a special feature of OSA's Optics InfoBase, http://vjbo.osa.org/virtual_issue.cfm).
59. Niu GG, Sapoznik E, Lu P, Criswell T, Mohs AM, Wang G, Lee SJ, Xu Y, Soker S: Fluorescent imaging of endothelial cells in bioengineered blood vessels: The impact of cross-linking of the scaffold. Journal of Tissue Engineering and Regenerative Medicine, doi: 10.1002/term.1876, 2014.
60. Zhao LL, Yang H, Cong WX, Wang G, Intes X: Lp regularization for early time-gate reconstruction in time-domain fluorescence molecular tomography. Optics Letters 39:4156-4159, 2014 (selected by the Editors, Andrew Dunn and Anthony Durkin, for publication in the Virtual Journal for Biomedical Optics (VJBO), http://vjbo.osa.org/virtual_issue.cfm).
61. Cong WX, Wang C, Wang G: Stored luminescence computed tomography. Applied Optics 53:5672-5676, 2014 (selected for inclusion in Virtual Journal for Biomedical Optics (VJBO) 9(11), Nov. 6, 2014).
62. Cong WX, Pan ZW, Filkins R, Srivastava AM, Ishaque N, Stefanov P, Wang G: X-ray micro-modulated luminescence tomography in dual-cone geometry. Journal of Biomedical Optics 19:076002(1-5), 2014.
63. Cong WX, Wang G: X-ray fan-beam luminescence tomography. Austin J Biomed Eng. 1(5):1024, 2014
64. Cong WX, Xi Y, Wang G: X-ray fluorescence computed tomography with polycapillary focusing. IEEE Access 2:1138-1142, 2014.
65. Gurjarpadhye AA, DeWitt MR, Xu Y, Wang G, Rylander MN, Rylander CG: Dynamic assessment of the endothelialization of tissue-engineered blood vessels using an OCT catheter-based fluorescence imaging system. Tissue Engineering (Part C Methods):DOI:10.1089/ten.TEC.2014.0345, 2014.
66. Pian Q, Wang C, Chen XL, Liang JM, Zhao LL, Wang G, Intes X: Multimodal biomedical optical imaging: Towards comprehensive investigation of biological tissues. Current Molecular Imaging 3:72-87, 2014.