Chaur-Dong Hsu, MD, MPH, FACOG
Bruce C Wheeler, PhD
Adjunct Professor of Bioengineering

Education

BS, Physical Science (XII-B) History (XXI-B)

Massachusetts Institute of Technology

MS, PhD, Electrical Engineering

Cornell University, Ithaca, NY

Experience

2015- Present

Adjunct Professor of Bioengineering, University of California at San Diego

2012-2015

President Elect, President, Past President, IEEE EMBS (4 years)

2007-2012

Editor-in-Chief, IEEE Transactions on Biomedical Engineering (6 years)

2009-2012

Acting Chair, Department of Biomedical Engineering, University of Florida (4 years)

2008-2015

Professor of Biomedical Engineering, University of Florida. Emeritus since 2015

2004-2008

Professor of Bioengineering, University of Illinois. Emeritus since 2008

2002-2008

Director (2 yrs) then Interim (Founding) Head, Department of Bioengineering (4 years)

1995-2001

Associate Head, ECE Dept., University of Illinois (6 years)

1990-1993

Chair, Neuroscience Graduate Program, University of Illinois (3 years)

1989-1990

Chair, Bioengineering Faculty, University of Illinois (1 year)

1971-1974

Teacher, Schenectady NY, Blacksburg VA

 

Biography

Bruce Wheeler moved to the University of California at San Diego in 2015 as an Adjunct Professor of Bioengineering with duties principally aimed at supporting the new Systems Bioengineering major at UCSD. He served 7 years at the University of Florida and 28 years at the University of Illinois at Urbana-Champaign. At Illinois he wrote the successful proposal for the BS, MS, PHD and Department of Bioengineering and served as Director and then Founding and Interim Head from Jan 2003 to Jan 2008. He was also a Professor of Electrical and Computer Engineering and of the Beckman Institute; he served as Chair of the Neuroscience Program and as Associate Head for Undergraduate Affairs of the Electrical and Computer Engineering Department. For four years at Florida he served as Acting Chair of the J. Crayton Pruitt Family Department of Biomedical Engineering where he co-authored the proposal for the BS BME degree.

In Jan 2013 he began a two year term as President of the IEEE Engineering in Medicine and Biology Society, the world’s largest, oldest, and most global bioengineering society. He strongly advocated for Biomedical and Health Informatics as the fastest growing component of biomedical engineering. From Jan 2007 to Dec 2012 he was Editor in Chief of the IEEE Transactions on Biomedical Engineering, the oldest, likely the largest and certainly one of the most influential general biomedical engineering journals.

Prof. Wheeler’s research interests lie in the application of electrical engineering methodologies to neuroscience. His work influenced the development of neural spike sorting technologies, demonstrated that microelectrode array recording from brain slices was possible and productive, and has been a leader in the development of lithography to control cells, especially neurons, in culture. This work aims at basic science understanding of the behavior of small populations of neurons, in hopes of creating better insight into the functioning of the brain. He has had funding from various agencies, including NIH, NSF, Whitaker, the USDA, and the American Epilepsy Foundation. Current funding is an NIH R01 grant.

He is a Fellow of AAAS, IEEE, BMES, AIME, and IAMBE. He is likely the only person to start two undergraduate BME degree programs. He is Emeritus Professor at Illinois and Florida.

 

Research Interest

  • Technologies for the Study of Small Neuronal Networks: Micropatterning the Growth of Individual Neurons
  • Microelectrode Array Fabrication
  • Neural Signal Processing
  • Biomedical Engineering & Signal Processing

 

Scientific Activities:

Honors & Awards
  • Distinguished Service Award, IEEE Engineering in Medicine and Biology Society (EMBS), 2016
  • Fellow of the International Academy of Medical and Biological Engineering (2014)
  • President of the IEEE Engineering in Medicine and Biology Society (2013-2014)
  • Fellow of the American Association for the Advancement of Science (2014), the Institute for Electrical and Electronic Engineering (2008), the Biomedical Engineering Society (2013), and the American Institute for Medical and Biological Engineering (2004)
  • Editor-in-Chief, IEEE Transactions on Biomedical Engineering (2006-2012)
  • Acting Chair, Department of Biomedical Engineering, University of Florida (2009-2012)
  • Founding and Interim Head, Department of Bioengineering, University of Illinois (2004-2008)
  • Outstanding MD/PhD Advisor (2003), Campus Wide Award for Outstanding Advising (2000), Dad’s Association Campus Wide Outstanding Professor (1999), Knight of St. Pat Outstanding Engineering Faculty Recognition (1999), Pierce Award for Student/Facutly Relations (1987), University of Illinois.
  • Phi Beta Kappa (1971), Eta Kappa Nu (1980)
  • Advisory Board Member: Bernstein Center for Computational Neuroscience, University of Freiburg, Germany (2012-2014); Department of Biomedical Engineering, Worcester Polytechnical Institute (2012-2013); Department of Biomedical Engineering, University of Florida (2003-2008); Department of Biological and Environmental Engineering, Cornell University (2004-2008); Department of Brain and Bio Engineering, Korea Advanced Institute for Science and Technology (2007).
  • NCAA Postgraduate Fellowship (1971), MVP Greater Boston Baseball League (1970), MIT Senior Athlete of the Year (1971), Mohonasen High School Athletic Hall of Fame (2010)
Grants

Active Support as PI

NIH. PI: Wheeler. Engineering Form and Function in Neuronal Networks. R01. 2012-2017. $1,881,508 total (subcontract Southern Illinois (now UC Irvine) ~40%)+ UFL direct+indirect (~50% IDC rate))

Previous External Funding as PI or with Substantial Involvement as Co-PI

  • IEEE Transactions on Biomedical Engineering. Editor in Chief Support. $63k/year, 2007-2012 (6 years).
  • NIH. PI: Wheeler. Engineering Form and Function in Neuronal Networks. R01. 2006-2011. Direct/Indirect $931k, $380k; subcontract to SIUSM Direct/Indirect $670/270k.]
  • NIH: R01 EB 000786 BRP program, 2002-2007, Development and Information Processing in 3-D Patterned Neural Circuits, subcontract from Georgia Tech, DeWeerth PI; UIUC component: Wheeler, PI approx $500k direct over 5 years.
  • Information Processing in Designed Neuronal Circuits, PI: Wheeler, Co-PI: Brewer. 2002-2006, NSF. $1,156,000 total direct+indirect.
  • Project FROG (for hearing aid algorithm development). Phonak. PI: Feng. Co-PIs: Wheeler, Jones, 10% effort. $330,000 annual, 11/00-6/01; $550,00 annual, 6/01-6/03.
  • NIH: PHS 1 F30 MH12397-02 PI: Wheeler, 2000-2005. Studies of living, sparse, patterned neural network. Support for pre/post doctoral student John Chang.
  • Real Time Implementation of Intelligent Hearing Aids. NIH. $150,000 total direct, two years plus extension. PI: Wheeler. 7/00-6/03.
  • DARPA Subcontract from SUNY Binghamton. Development of a Biomimetic Acoustic Microsensor. 9/29/00-9/28/03. $179,525 annual. (PI: Jones; coinvestigator: Feng, Wheeler, O’Brien, 5% effort).
  • Micropatterned Neural Networks. NIH. $150,000. 10/99-4/02. PI: BC Wheeler (10% time)
  • Microstamping Proteins and Micropatterning Neurons. NIH. $100,000. 10/98-10/00. PI BC Wheeler (10% time)
  • U.S.-Korea Cooperative Research: Micropatterned Neural Networks and Microelectrode Arrays. NSF: PI: BC Wheeler. $16, 504 direct costs, 1999-2001 (travel support).
  • Optimizing Data Processing Systems for Grain Evaluation. US Dept. Agriculture, Northern Regional Research Center, Peoria IL. 07/95-07/99. PI: BC Wheeler. $18,000.
  • Bioengineering Curriculum Development at UIUC: Engaging Non-Science Majors and Future Teachers. Whitaker Foundation. 8/93-8/96. PIs: RL Magin, B Bruce. Duration: 3 years. Total: $452,568. Role: coinvestigator.
  • Novel Sensors to Monitor Solid-Substrate Fermentations, Biotechnology Research and Development Corporation, PI: BC Wheeler. 6/89-7/94. Total: $169,656.
  • Investigation of Neuronal Spike Recognition Algorithms, PI BC Wheeler. (Subcontract to NIH SBIR Phase II Program, Spike Detector for Multichannel Neuronal Data Acquisition, PI: Harvey Wiggins, Spectrum Scientific, Dallas.) 4/91-3/93. $77,593 total.
  • Investigation of Neuronal Spike Recognition Algorithms, $4270, UIUC Research Board, 1 year, 1992.
  • Patterned Neuronal Networks, NIH. PI: Bruce C. Wheeler. 10% effort. 4/91-3/93. Direct Cost: $70,000.
  • Spike Detector for Multichannel Neuronal Acquisition, consultant, (PI H. Wiggins, Spectrum Scientific, Dallas, $45,600, 1 year.)
  • Spatial Description Of Epileptiform Activity In The Hippocampal Slice With A Microelectrode Array, $25,000, 1 year, Epilepsy Foundation of America, 1987-8.
  • 3M Faculty Award, $20,000, 1984-6. Research Gift for Electrode Array And Microsensor Studies.
  • Fabrication Of Buried Membrane Ion-Selective Field Effect Transistors,$39,000,NSF ECS83-07399,1983-6.
  • Fabrication and Use of Microelectrode Arrays For Neural Recording, $114,882, Whitaker Foundation, 1982-4.
Patents Granted
  1. Feng, A.S., Lansing, C.R., Liu, C., O'Brien, W.D. and Wheeler, B.C. "Binaural Signal Processing System and Method" Patent issued on April 24, 2001. (US Patent #6,222,927).
  2. Feng, A.S., Liu, C., Jones, D.L., Bilger, R.C., Lansing, C.R., O’Brien, W.D, Wheeler, B.C., “Binaural Signal Processing Using Multiple Acoustic Sensors and Digital Filtering,” US Patent 6,978,159 B2, Dec. 20, 2005.
  3. Feng, A.S., Liu, C., Bilger, R.C., Jones, D.L., Lansing, C.R., O’Brien, W.D, Wheeler, B.C., “Binaural Signal Processing Techniques,” US Patent 6,987,856 B1, Jan. 17, 2006.Canadian Patent #2,348,894 issued on 09/25/2007; European Patent #1133899 issued on August 6, 2008.
  4. Feng, A.S., Lockwood, M.E., Jones, D.L., Bilger, R.C., Lansing, C.R., O'Brien, W.O., Wheeler, B.C. - System and Methods for Interference-Suppression with Directional Sensing Patterns. US Patent # 7,076,072 issued on July 11, 2006.
  5. Feng AS, Jones DL, Wheeler BC, Bilger RC, Lansing CR, O'Brien WD - "Intrabody communication for a hearing aid" - US patent #7,206,423 B1, issued on 4/17/2007; DE 195 41 648 C2; WO 01/87014 A2.
  6. Jones, D.L., Lockwood, M.E., Bilger, R.C., Feng, A.S., Lansing, C.R., O'Brien, W.D., Wheeler, B.C., Elledge, M. and Liu, C. Interference suppression techniques. - US Patent # 7,613,309 B2 (issued on Nov 3, 2009). European patent #1 312 239 (issued on 12/27/2006). Canadian Patent #2407855 (issued on Feb 2, 2010)
  7. Feng, A.S., Lockwood, M.E., Jones, D.L., Bilger, R.C., Lansing, C.R., O'Brien, W.O., Wheeler, B.C. - System and Methods for Interference-Suppression with Directional Sensing Patterns. US Patent # 7,577,266 (issued Aug 18, 2009).
  8. O'Brien, W.D., Feng, A.S., Wheeler, B.C., Lansing, C.R., Bachler, H, and Bilger, R.C. Intrabody Communication with Ultrasound. US Patent 7,945,064 B2, issued May 17, 2011.
  9. Ross, J, Brown, EA, Rajaraman, S, Wheeler, B. Apparatus and methods for high throughput network electrophysiology and cellular analysis. US Patent 9290756, issued March 22, 1026.

 

Publications

Invited / Reviewed
  1. Nam, Y. and Wheeler, B.C. (2011) In vitro microelectrode array technology and neural recordings. Critical Reviews in Biomedical Engineering, 39(1): 45-62.
  2. Wheeler, B.C. and Brewer, G.J. (2010) Designing Neural Networks in Culture, Proceedings of the IEEE, 98(3) (March), 398-406, DOI: 10.1109/JPROC.2009.2039029.
Peer Reviewed
  1. Bhattacharya, A, Desai, H., DeMarse, TB, Wheeler, BC, and Brewer, GJ. (2016) Repeating motifs of CA3 activity dependent on engineered inputs from dentate gyrus neurons in live hippocampal networks, accepted, Frontiers in Neural Circuits.
  2. DeMarse, TB, Pan, L, Alagapan, S, Leondopulos, S., Franca, E, Brewer, GJ, and Wheeler, BC. (2016) Feed-Forward Propagation of Temporal and Rate Information Between Cortical Populations During Coherent Activation in Engineered In Vitro Networks, 22-April-16, Frontiers in Neural Circuits. doi: 10.3389/fncir.2016.00032
  3. Alagapan, S, Pan, L, Leondopulos, S, Franca, E, Wheeler, BC and DeMarse, TB. (2016) Structural-Functional Properties and Propagation of Information Across Two, Four, and Eight Degree In vitro Network Topologies, Frontiers in Bioengineering and Biotechnology, Feb 2016, doi: 10.3389/fbioe.2016.00015.
  4. Franca, E, Jao, PF, Fang, S-P, Alagapan, S, Pan, L, Yoon, JH, Yoon, YK, Wheeler, BC (2016). Scale of carbon nanomaterials affects neural outgrowth and adhesion strength. IEEE Trans. Nanobioscience. doi:10.1109/TNB.2016. PMCID: PMC4791169
  5. Pan, L, Alagapan, S, Franca, E., DeMarse, T, Leondopulos, SS, Brewer, GJ, Wheeler, BC (2015). An in vitro method to manipulate the direction and functional strength between neural populations. Frontiers in Neural Circuits, Frontiers in Neural Circuits, doi: 10.3389/fncir.2015.00032.
  6. Jao, PF, Franca, E, Fang, SP, Wheeler, BC, Yoon, Y-K. (2015) Immersion lithographic patterning of electrospun nanofibers for carbon nanofibrous microelectrode arrays (CNF-MEAs). IEEE J. Microelectromechanical Systems, 24(3), 703-715. DOI: 10.1109/JMEMS.2014.2346503
  7. Pan, L, Alagapan, S, Franca, E., DeMarse, T, Brewer, GJ, Wheeler, BC. (2014) Large extracellular spikes recordable from axons in microtunnels. IEEE Trans. Neural Systems and Rehab. Engineering 22(3),453-459. DOI: 10.1109/TNSRE.2013.2289911.
  8. Brewer, GJ, Boehler, MD, Leondopulos, S, Pan, L, Alagapan, S., DeMarse, TB, Wheeler, BC. (2013) Toward a self-wired active reconstruction of the hippocampal trisynaptic loop: DG-CA3. Frontiers in Neuroscience, v7, article 165, doi: 10.3389/fncir.2013.00165, Oct 2013.
  9. Leondopulos, SS, Boehler, MD, Wheeler, BC, Brewer, GJ. (2012) Chronic stimulation of cultured neuronal networks boosts low-frequency oscillatory activity at theta and gamma with spikes phase-locked to gamma frequencies J. Neural Engineering. 9, 026015 doi:10.1088/1741-2560/9/2/026015.
  10. Boehler, MD, Leondopulos, SS, Wheeler, BC, Brewer, GJ. (2012) Hippocampal networks on reliable patterned substrates. J. Neurosci. Meth. 203:344-353. doi: 10.1016/j.jneumeth.2011.09.020
  11. Pan, L., Alagapan, S., Franca, E., Brewer, GJ, Wheeler, BC, (2011) Propagation of action potential activity in a predefined microtunnel neural network, J. Neural Eng. 8, 046031. doi:10.1088/1741-2560/8/4/046031.
  12. Ide, AN, Andruska, A, Boehler, MD, Wheeler, BC, and Brewer, GJ. (2010) Chronic Network Stimulation Enhances Evoked Action Potentials. J. Neural Eng. 7, 016008 (15 pp) doi: 10.1088/1741-2560/71/1/016008.
  13. Brewer, GJ, Boehler, MD, Ide, AN, and Wheeler, BC. (2009) Chronic electrical stimulation of hippocampal networks during development increases spontaneous spike rates, J. Nsci. Meth., 184, 104-109. NIHMSID#137731. Publ.ID NSM5380. PubMed#19666055.
  14. Musick, K., Khatami, D., and Wheeler, B.C. (2009) Three-dimensional microelectrode array for recording dissociated neuronal cultures, Lab on Chip, 9, 2036-2042. DOI: 10.1039/b820596e.
  15. Nam, Y., Brown, E.A., Ross, J.D., Blum, R.A., Wheeler, B.C., DeWeerth, S.P., (2009) A retrofitted neural recording system with a novel stimulation IC to monitor early neural responses from a stimulating electrode. J. Neurosci. Meth. 178, 99–102.
  16. Dworak, B.J., and Wheeler, B.C., (2009) Novel MEA platform with PDMS microtunnels enables detection of action potential propagation from isolated axons in culture, Lab on Chip, 9, 404-410.
  17. Brewer, G.J., Boehler, M.D., Pearson, R.A., DeMaris, A.A., Ide, A.N., Wheeler, B.C. (2009), Neuron network activity scales exponentially with synapse density, J. Neural Eng. 6., 014001, doi:10.1088/1741-2560/6/1/014001.
  18. Brown, E.A., Ross, J.D., Blum, R.A., Nam, Y., Wheeler, B.C., DeWeerth, S.P. (2008) Stimulus-artifact elimination in a multi-electrode system. IEEE Trans. Biomed. Circuits and Systems, 2 (1), March., 10-21.
  19. Brewer, G. J.; Boehler, M. D.; Jones, T. T.; Wheeler, B. C., (2008) NbActiv4 medium improvement to Neurobasal/B27 increases neuron synapse densities and network spike rates on multielectrode arrays. Journal of Neuroscience Methods, 170, (2), 181-187.
  20. Boehler, MD, Wheeler, BC, and Brewer, GJ. (2007) Added astroglia promote greater synapse density and higher activity in neuronal networks, Neuron Glia Biology, 3(2):127-140.
  21. Vieira, M.; Christensen, B. L.; Wheeler, B. C.; Feng, A. S.; Kollmar, R., (2007) Survival and stimulation of neurite outgrowth in a serum-free culture of spiral ganglion neurons from adult mice. Hearing Research, 230, (1-2), 17-23.
  22. Nam, Y, Brewer, GJ, Wheeler, BC. (2007) Development of astroglial cells in patterned neuronal cultures, J. Biomaterials Science, Polymer Edition, 18(8), 1091-1100.
  23. Rowe, L., Almasri, M., Lee, K., Fogleman, N., Brewer, G.J Nam, Y., Wheeler, B.C., Vukasinovic, J., Glezer, A., Frazier, A.B. (2007) Active 3-D Microscaffold System with Fluid Perfusion for Culturing in Vitro Neuronal Networks, Lab on a Chip (4),475-482.
  24. Chang, J.C., Brewer, G.J, Wheeler, B.C. (2006) Neuronal network structuring induces greater neuronal activity through enhanced astroglial development, J. Neuroeng. 3, 217-226.
  25. Nam, Y., Musick, K., and Wheeler, B.C. (2006) Application of a PDMS microstencil as a replaceable insulator toward a single-use planar microelectrode array, Biomedical Microdevices, 8(4), 375-381.
  26. Phatak, SA, Ratnam, R, Wheeler, BC, O'Brien, WD, Jr., Feng, AS (2006). Effect of reflectors on sound source localization with two microphones, J. Audio Eng. Soc., 54 (6), 512-524. ]
  27. Nam, Y., Branch, D.W., and Wheeler, B.C. (2006) Epoxy-silane linking of biomolecules is simple and effective for patterning neuronal cultures, Biosensors and Bioelectronics, 22(5), 589-597.
  28. Nam, Y, Wheeler, B.C., and Heuskel, M.O. (2006) Neural recording and stimulation of dissociated hippocampal cultures in vitro using microfabricated three dimensional tip electrode array, J. Nsci. Meth., 155 (2), 296-299.
  29. Nam, Y., Chang, J.C., Khatami, D., Brewer, G.J., and Wheeler, B.C., (2004) “Patterning to enhance activity of cultured neuronal networks”, IEE Proc. Nanobiotechnology, 151(3), 109-115.
  30. Larsen, J., Lansing, C., Bilger, R., Wheeler, B., Phatak, S., Lockwood, M., O’Brien, W., Jr., and Feng, A.S, (2004) “Speech perception in noise with a two-sensor FMV beamforming algorithm”, Acoustics Research Letters Online, 5(3), 100-105.
  31. Lockwood, M.E., Jones, A.L., Bilger, R.C., Lansing, C.R., O'Brien, W.D., Wheeler, B.C. and Feng, A.S., (2004) “Performance of time-and frequency-domain binaural beamformers based on recorded signals from real rooms,” J. Acoust. Soc. Am., 115, 379-391.
  32. Nam, Y., Chang, J.C., Wheeler, B.C., Brewer, G.J., (2004) “Gold coated microelectrode array with thiol linked self-assembled monolayers to engineer neuronal cultures”, IEEE Trans Biomed. Eng., 51(1), 158-165, January.
  33. Ratnam, R., Jones, D.L., Wheeler, B.C., O’Brien, W.D., Jr., Lansing, C., Bilger, R.C., and Feng, A.S., (2003) “The blind estimation of reverberation time,” J. Acoust. Soc. Am., 114, 2877-2892.
  34. Chang, J.C., Brewer, G.J., Wheeler, B.C. (2003) “A Modified Microstamping Technique Enhances Polylysine Transfer and Neuronal Cell Patterning”, J. Biomaterials, 24(17) (August): 2863-2870.
  35. Cornish T, Branch DW, Wheeler BC, Campanelli JT (2002) “Microcontact printing: a versatile technique for the study of synaptogenic molecules,” Mol. Cell. Neurosci. 20(1):140-53.
  36. Liu, C., Wheeler, B.C., O'Brien, W.D. Jr., Bilger, R.C., Lansing, C.R., Feng, A.S. (2001) “A two microphone dual delay-line approach for extraction of a speech sound in the presence of multiple interferers,” J. Acoust. Soc. Amer., 110(6), 3218-3231.
  37. Chang, J.C., Brewer, G.J., and Wheeler, B.C., (2001) "Modulation of neural network activity by patterning", Biosensors and Bioelectronics, 16 (7-8) (Sept): 527-533.
  38. Branch, DW, Wheeler, BC Brewer, GJ & D.E. Leckband, DE (2001) “Long-term stability of microstamped sub-strates of polylysine and grafted polyethylene glycol in cell culture conditions,” J. Biomaterials,22, 1035-1047.
  39. Chang, J.C., Wheeler, B. C., and Brewer, G. J. (2000) "Microelectrode array recordings of patterned hippocampal neural networks for four weeks," Biomedical Microdevices, 2:4, 245-253.
  40. Venkateswar, R.A., Wheeler, B.C., and Branch, D.W. (2000) "An electrophoretic method for producing patterned biomolecule gradients," Biomedical Microdevices, 2:4, 255-264.
  41. Branch, D.W., Wheeler, B.C., Brewer, G.J., and Leckband, D. (2000) “Long-term maintenance of patterns of hippocampal pyramidal cells on substrates of polyethylene glycol and microstamped polylysine,” IEEE Trans. Biomed. Eng., 47, 290-300.
  42. Liu, C., Wheeler, B.C., O’Brien, W.D., Jr., Bilger, R.C., Lansing, C.R., and Feng, A.S. (2000) “Localization of multiple sound sources with two microphones in complex acoustic environments,” J. Acoust. Soc. Amer., 108(4), 1888-1905.
  43. Wheeler, B.C., Corey, J.M., Brewer, G.J., & Branch, D.W (1999), “Microcontact printing for precise control of nerve cell growth in culture,” J. Biomech. Eng., 121, 73-78.
  44. Gordon, S.H, Wheeler, B.C., Schudy, R.B., Wicklow, D.T., and Greene, R.V. (1998). “Neural network pattern recognition of photoacoustic FTIR spectra and knowledge-based techniques for detection of mycotoxigenic fungi in food grains,” J. of Food Protection, 61(2), 221-230.
  45. Branch, D.W., Corey, J.M., Weyhenmeyer, J. A., Brewer, G. J., & Wheeler, B.C. (1998) “Micro-stamp patterns of biomolecules for high-resolution neuronal networks,”Med. & Biol. Comp. & Eng., 36, 135-141.
  46. Corey, J.M., Brunette, A.L., Chen, M.S., Weyhenmeyer, J.A., Brewer, G.J., and Wheeler, B.C.(1997), “Differentiated B104 neuroblastoma cells are a high-resolution assay for micropatterned substrates,” J. Neurosci. Methods, 75, 91-97.
  47. Gordon, S.H., Schudy, R.B., Wheeler, B.C., Wicklow, D.T., & Greene, R.V. (1997) “Identification of Fourier transform infrared photoacoustic spectral features for detection of aspergillis flavus infection in corn,” Int. J. Food Microbiol., 35, 179-185.
  48. Corey, J.M., Wheeler, B.C., & Brewer, G.J. (1996) "Micrometer resolution silane-based micropatterning of hippocampal neurons: a comparison of photoresist and laser ablation methods for fabricating substrates," IEEE Trans. Biomed. Eng., 43, 944-955.
  49. Gordon, S.H., Greene, R.V., Wheeler, B.C., and James, C. (1993) “Multivariate FTIR analysis of substrates for protein, polysaccharide, lipid and microbe content: Potential for solid-state fermentations,” Biotechnology Advances, 11, 665-675.
  50. Boppart, S., Wheeler, B.C., and Wallace, C. (1992) "A flexible, perforated microelectrode array for extended neural recordings," IEEE Trans. Biomed. Eng., BME-39, 37-42.
  51. Corey, J.L, Wheeler, B.C., and Brewer, G.J. (1991) "Compliance of hippocampal neurons to patterned substrate networks," J. Neurosci. Res., 30, 300-307.
  52. Willming, D.A. and Wheeler, B.C. (1990) "Real-time multichannel neural spike recognition with DSPs," IEEE EMBS Magazine, 9, 37-40.
  53. Novak, J.L. and Wheeler, B.C. (1989) "Two-dimensional current source density analysis of propagation delays for components of epileptiform bursts in rat hippocampal slices," Brain Res., 497, 223-230.
  54. Novak, J.L. and Wheeler, B.C. (1989) "A high-speed multichannel neural data acquisition system for IBM PC compatibles," J. Neurosci. Meth., 26, 239-247.
  55. Novak, J.L. and Wheeler, B.C. (1988) "Multisite hippocampal slice recording and stimulation using a 32 element microelectrode array," J. Neurosci. Meth., 23, 149-159.
  56. Smith, S.R. and Wheeler, B.C. (1988) "A real-time multiprocessor system for acquisition of multichannel neural data," IEEE Trans. Biomed. Eng., BME-25, 875-877.
  57. Wheeler, B.C. and Smith, S.R. (1987) "High-resolution alignment of action potential waveforms using cubic spline interpolation," J. Biomed. Eng., 10, 47-53, 1987.
  58. Wheeler, B.C. and Novak, J.L. (1986) "Current source density estimation using microelectrode array data from the hippocampal slice preparation," IEEE Trans. Biomed. Eng., BME-33, 1204-1212, 1986.
  59. Novak, J.L. and Wheeler, B.C. (1986) "Recording from the Aplysia abdominal ganglion with a planar microelectrode array," IEEE Trans. Biomed. Eng., BME-33, 196-202.
  60. Wheeler, B.C. (1985) "Exercises for an introductory image processing class," IEEE Trans.Educ., E-28,31-35.
  61. Wheeler, B.C. and Valesano, W.R. (1985) "A real-time digital filter based data acquisition system for the detection of neural signals," Med. & Biol. Eng. & Comput., 23, 243-248.
  62. Wheeler, B.C. and Heetderks, W.J. (1982) "A comparison of techniques for classification of multiple neural signals," IEEE Trans. Biomed. Eng., BME-29, 752-759.
  63. Kim, M., Wheeler, B.C., Shin, K.B., and Perry, S. (1979) "Design of optimal chemotherapy schedules using kinetic models for cancerous and normal tissues, " J. Cybernetics & Info.Science, 2, 92-108.
  64. Kim, M., Wheeler, B.C., and Perry, S. (1978) "Quantitative description of cell cycle kinetics under chemotherapy utilizing flow cytometry, " Cell Tissue Kinetics, 11, 497-512.
Submitted and in Preparation
  1. DeMarse, TB, Boehler, MD, Leondopulos, S, Brewer, GJ, and Wheeler, BC. Neuronal Avalanches Across a Cascade of Regional Hippocampal Preparations, submitted, PLOS.
  2. Poli, D, Thiagarajan, S., DeMarse, TB, Wheeler, BC, and Brewer, GJ. Sparse and specific coding during information transmission between reconstructed dentate gyrus and CA3 hippocampal networks, submitted, Frontiers in Neural Circuits.
Book Chapters
  1. Chang, J.C., and Wheeler, B.C., (2006) “Pattern technologies for structured neuronal networks on MEAs,” book chapter in Advances in Network Electrophysiology using Multi Electrode Arrays, M. Taketani and M. Baudry (eds), Kluwer Academic/Plenum.
  2. Wheeler, B. C. (1998) “Automatic discrimination of single units,” in M. Nicolelis, Ed., Methods for Neural Ensemble Recordings, CRC Press, Ch. 4, 61-77.
  3. Wheeler, B. C., & Brewer, G. J. (1994). “Multineuron patterning and recording”, in McKenna & Stenger (Eds.), Enabling Technologies for Cultured Neural Networks, 167-185, Academic Press.
  4. Novak, J. L. & Wheeler, B. C. (1987) “Epileptiform activity recorded simultaneously at multiple sites on the surface of a hippocampal slice with a planar microelectrode array,” in Brain Slices: Fundamentals, Applications and Implications, A.Schurr, TJ Teyler, & M.Tseng, Eds, S.Karger, Basel, Switzerland, 177-183.
Editorials
  1. Dhawan, AP, Heetderks, WJ, Pavel, M, Acharya, S, Akay, M, Mairal, A, Wheeler, BC, Dacso, CC, Sunger T, Lovell, N, Gerber, M, Shah, M, Senthilvel, SG, Wang, MD, Bhargava, B (2015) Current and Future Challenges in Point-of-Care Technologies: A Paradigm-Shift in Affordable Global Healthcare With Personalized and Preventive Medicine. IEEE J. Translational Engineering in Health and Medicine. DOI: 10.1109/JTEH.2015.2400919.
  2. Wheeler, BC (2015). Passing the Torch. IEEE PULSE, Jan/Feb 2015.
  3. Wheeler, BC (2014) Balancing Biology and Engineering in Bioengineering, IEEE PULSE, Sept/Oct 2014.
  4. Wheeler, BC (2014) The Nature of Engineering Professions and Bioengineering, IEEE PULSE, May/June 2014.
  5. Wheeler, BC (2014) Biomedical and Health Informatics: Prospects for the Future and the Future of Our Students. IEEE PULSE March/April 2014.
  6. Wheeler, BC (2014) EMBS at Half A Century: IEEE’s Original Life Science and Biomedical Engineering Initiative Grows Stronger Every Year. IEEE PULSE January/February 2014.
  7. Wheeler, BC (2013) Neural Engineering Takes Center Stage. IEEE PULSE November/December 2013.
  8. Wheeler, BC (2013) The Many Flavors of Bio, Medical, and Health Informatics. IEEE PULSE July/August 2013.
  9. Wheeler, BC (2013) Point of Care Technologies. IEEE PULSE May/June 2013.
  10. Wheeler, BC (2013) It’s a Great Time to Be Treated by a Biomedical Engineer. IEEE PULSE March/April 2013.
  11. Wheeler, BC (2013) It’s a Great Time to Be a Biomedical Engineer. IEEE PULSE January/February 2013.
  12. Wheeler, BC (2012) Bringing a Chapter to A Close, IEEE Trans. Biomed. Eng., 59(12), 3275.
  13. Dhawan, AP, Wheeler BC (2012) Editorial: Introducing TBME Letters Special Section on Multiscale Biomedical Signal and Image Modeling and Analysis, IEEE Trans Biomed. Eng., 59 (1), 3.
  14. Dhawan, AP, Wheeler, BC (2011) Introducing TBME Letters - Special Issue on Multiscale Modeling and Analysis in Computational Biology and Medicine: Part – 2, IEEE Trans. Biomed. Eng., 58 (12), 3431-3433.
  15. Dhawan, AP, Wheeler, BC (2011) Introducing TBME Letters - Special Issue on Multiscale Modeling and Analysis in Computational Biology and Medicine: Part – 1, IEEE Trans. Biomed. Eng., 58 (10), 2935.
  16. Wheeler, BC, Thakor N, He, B. (2011) Special Section on Grand Challenges in Neuroengineering IEEE Trans. Biomed. Eng., 58(7), 1883.
  17. Wheeler, BC (2011) Editorial – Our Response to Growth Emphasizing Impact, Novelty, and Validation, IEEE Trans. Biomed. Eng., 58 (4), 843-844.
  18. Dhawan, AP, Wheeler BC (2011) Editorial: Introducing TBME Letters Special Issue on Emerging Technologies in Point-of-Care Health Care, IEEE Trans Biomed. Eng., 58 (3), 731.
  19. Dhawan, AP, Wheeler BC (2010) Introducing TBME Letters Special Issue on Multiparameter Optical Imaging and Image Analysis, IEEE Trans Biomed. Eng., 57 (10), 2555.
  20. Dhawan, AP, Wheeler BC (2010) Introducing TBME Letters and Regular Papers Special Issue on Therapeutic Ultrasound, IEEE Trans Biomed. Eng., 57 (1), 3.
  21. Dhawan, AP, Wheeler BC (2009) Introducing TBME Letters Special Issue on Neuroengineering and Neuroprosthetics, IEEE Trans Biomed. Eng., 56 (11), 2687.
  22. Dhawan, AP, Wheeler BC (2009) Introducing TBME Letters Special Issue on Biomedical Robotics and Biomechatronics, IEEE Trans Biomed. Eng., 56 (2), 2291.
  23. Wheeler, BC (2007) The Tradition Continues to Improve. IEEE Trans. Biomed. Eng., 54(1), 1.
Other/Popular
  1. Wheeler, BC (2014) IEEE Technology Time Machine Takes on the Future of Health. Medical Design Technology. Oct 9, 2014.
Conference and Other Papers/Posters/Abstracts
  1. DeMarse, TB, Poli, D., Brewer, GJ, Wheeler, BC. Time Evolution Of Spike Activity In Hippocampal Neurons During Paired-Pulse Stimulation Of DG-CA3 Reconstructed Networks, MEA 2014 (10th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2016.
  2. Poli, D., Thiagarajan, S., DeMarse, TB, Wheeler, BC, Brewer. Leader-Broker Dynamics Within Rich-Club Networks Across DG-CA3, DG-DG, CA3-CA3, and Random Hippocampal MEA Culture, MEA 2014 (10th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2016.
  3. DeMarse, T, Poli, D, Brewer, GJ, Wheeler, BC. On The Role Of Rich Club Topologies During Information Transmission Among Cell Assemblies Across Hippocampal Dentate And Ca3 Co-Cultured In Vitro Networks. AREADNE 2016 (Research in Encoding and Decoding of Neural Ensembles). Santorini Greece, 22-26 June.
  4. Fang, S-P, Jao, PF, Franca, E, DeMarse, TB, Wheeler, BC, and Yoon, KY. A carbon nanofiber (CNF) based 3-D microelectrode array (MEA) for in-vitro neural proliferation and signal recording. IEEE MEMS 2016 conference, Jan 24-28, 2016, Shanghai, China.
  5. Brewer, GJ, Bhattacharya, A, DeMarse, TB, and Wheeler, BC. Spatial motifs in a living engineered hippocampal circuit, Abstract, Soc. for Neuroscience Annual Meeting, Chicago. Oct 2015
  6. Wheeler, BC, DeMarse, TB, Bhattacharya, A, Brewer GJ. Technologies for Engineering of Neuronal Architectures to Study Information Processing in Living Networks, BMES annual conference, Tampa FL Oct 2015
  7. DeMarse TB, Bhattacharya, A, Brewer GJ, Wheeler BC, Transmission of Information Among Cell-Assemblies within Engineered Hippocampal Networks, BMES annual conference, Tampa FL Oct 2015
  8. Bhattacharya, A, Wheeler, BC, DeMarse, TB, Brewer GJ. Spatial motifs in a living engineered hippocampal circuit, BMES annual conference, Tampa FL Oct 2015.
  9. DeMarse TB, Alagapan S, Brewer GJ, Wheeler BC (2015) On the Nature and Transmission of Information Among Cell-Assemblies In Engineered Neuronal Topologies. Bernstein Conference, Heidelberg-Mannheim Germany. Sept 15-17, 2015.
  10. Demarse, TB, Alagapan, S, Pan, L, Franca, L, Leondopulos, S, Brewer, GJ and Wheeler, BC. On the Nature and Transmission of Information Among Cell-Assemblies In Engineered Neuronal Topologies. NETT International Conference on System level Approaches to Neural Engineering, Barcelona, Spain, Sept 23, 2015.
  11. DeMarse, Bhattacharya, A, Brewer, GJ, Wheeler, BC. Transmission of Information Among Cell Assemblies in Engineered Living Hippocampal Networks. IEEE EMBS Annual Conference, Milan Italy, Aug 2015.
  12. Wheeler, BC, Brewer, GJ, DeMarse, TB. Transient Propagation of Information Among Cultured Hippocampal Cell Assemblies in a Two-Chamber MEMs Device. World Congress Medical Physics and Biomedical Engineering, Toronto, June 2015.
  13. Fang, SP, Jao, PF, Franca E, Machado, A, Wheeler BC, and Yoon YK. High aspect ratio nanofibrous microelectrode array for in vitro neural signal detection. NanoFlorida 2014, U. Miami, Sept 2014.
  14. DeMarse, T, Alagapan, S, Pan, L, Franca, E, Leondopulos, S, Brewer, GJ, Wheeler, BC, On the Nature and Transmission of Information Among Cell-Assemblies: A Network and Information Analysis of Propagation Between Neural Populations in a Two-Chamber In vitro System MEA 2014 (9th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2014.
  15. Brewer, GJ, Pan, L, Alagapan, S, Franca, E, DeMarse, T, Wheeler, BC, Four-Layer Closed-Loop Neuronal Networks MEA 2014 (9th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2014.
  16. Brewer, GJ, Leondopulos, S, Wheeler, BC, Pairwise Reconstruction of the Hippocampal Tri-synaptic Loop: EC-DG, DGCA3, CA3-CA1. MEA 2014 (9th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2014.
  17. Sheng-Po Fang, Pitfee Jao, Eric Franca, Bruce Wheeler, and Yong-Kyu Yoon, "High-Aspect-Ratio Carbon Nanofibrous Microelectrode Array (MEA) based on Immersion Photolithography," 2014 Annual Joint Symposium of the Florida Chapter of the American Vacuum Society and Florida Society of Microscopy, Orlando, FL, Feb. 3-4, 2014
  18. Jao, PF, Franca, E, Fang, SP, Yoon, J, Cho, K, Senior, DE, Kim, G, Wheeler, B, and Yoon, YK, Fabrication of Carbon Nanofibrous Microelectrode Array (CNF-MEA) Using Immersion Photolithography, MEMS conference, San Francisco, Jan 2014.
  19. Wheeler, BC, Brewer, GJ, Boehler, MD, Leondopulos, S, Pan, L, Alagapan, S., DeMarse, TB. Toward a self-wired active reconstruction of the hippocampal trisynaptic loop: DG-CA3. Poster, Society for Neuroscience, Nov 2013.
  20. Franca, E, Rapazzetti, V., Jao, PF, Yoon, YK, and Wheeler, BC. Preferential Neural Growth and Surface Treatment-Based Toxicity on Carbonized Nanofibers, Poster IEEE Neural Engineering Conference, San Diego, Nov 2013.
  21. DeMarse, TB, Alagapan, S, Pan, L., Franca, EW, Leondopulos, SS, Brewer, GJ, and Wheeler, BC. Feed-Forward Propagation of Information Between Neuronal Assemblies In Defined In Vitro Cortical Networks. Poster IEEE Neural Engineering Conference, San Diego, Nov 2013.
  22. Alagapan, S., Franca, EW, Pan, L, DeMarse, TB, and Wheeler, BC. Spatial Distribution of Functional Connection Strengths in Patterned Neuronal Networks of Varying Complexity. Poster IEEE Neural Engineering Conference, San Diego, Nov 2013.
  23. Pan, L., Alagapan, S, Franca, E, DeMarse, TB, Brewer, GJ, and Wheeler, BC. Four-Layer Closed-Loop Neural Networks. Poster. IEEE Neural Engineering Conference, San Diego, Nov 2013.
  24. Brewer, GJ, Boehler, MD, Leondopulos, S, Pan, L, Alagapan, S., DeMarse, TB, Wheeler, BC. Toward a self-wired active reconstruction of the hippocampal trisynaptic loop: DG-CA3. Poster IEEE Neural Engineering Conference, San Diego, Nov 2013.
  25. Wheeler, BC, Alagapan, S, Pan L, Franca, E, Brewer, GJ, and DeMarse, TB. Feed-forward information propagation in neuronal assemblies from defined in vitro cortical networks. BMES Meeting Seattle Fall 2013.
  26. Jao, PF, Franca, E, Kim, G, Wheeler, BC, and Yoon, YK. Photopatterned SU-8 derived carbon nanofibers for neural engineering applications. BMES Meeting Seattle Fall 2013.
  27. Wheeler, BC. Microtunnel technology for cultured neural networks. Minisymposium presentation. IEEE EMBS Annual Conference, Osaka, July 2013.
  28. Wheeler, BC, Alagapan, S, Pan L, Franca, E, Brewer, GJ, and DeMarse, TB. Feed-Forward Propagation of Information Between Neuronal Assemblies In Defined In Vitro Cortical Networks, poster presentation, BCCN Workshop on Dynamics of Neuronal Systems, Bernstein Center on Computational Neuroscience, Freiburg Germany, March 18-20, 2013.
  29. Franca, E., Keefer, E., Pan, L., Alagapan, S., Wheeler, BC. Neural toxicity and adhesion strength on layer-by-layer carbon nanotube depositions, BMES Meeting 2012, (October 25, 2012), Atlanta GA.
  30. Leondopulos, SS, Boehler, MD, Wheeler, BC, Brewer, GJ Network-correlated oscillations of 0.1-1 Hz determine network bursts and individual burst morphology in hippocampal networks on electrode arrays, Soc. for Neurosci. Washington DC. Nov 2012.
  31. Pan, L., Alagapan, S., Franca, E., DeMarse, TB, Wheeler, BC. Huge spikes recorded in Microtunnels. MEA 2012 (8th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2012.
  32. Alagapan, S., Franca, Pan, L., E., DeMarse, TB, Wheeler, BC. Effect Of Structural Connectivity On Spatial .Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2012.
  33. Pan, L, Alagapan, S, Franca, E, DeMarse, TB, Brewer, GJ, Wheeler, BC. Engineered Neural Networks with Micro-tunnels on Multi-Electrode Arrays. World Congress on Medical Physics and Biomedical Engineering, Beijing, China, May 2012
  34. Pan, L., Alagapan, S., Franca, E., DeMarse, TB, Brewer GJ, Wheeler, BC. Unidirectional burst propagation is controlled by strength of connectivity in a predefined neural network, Soc. for Neurosci. 2011.
  35. Alagapan, S., Pan, L., Wheeler, B.C., and DeMarse, T. Validation of Granger Causality within In Vitro Engineered Feed-Forward Cortical Networks, Front. Neuroinform. Conference Abstract: 4th INCF Congress of Neuroinformatics. (Sept 2011), Boston, MA doi: 10.3389/conf.fninf.2011.08.00163
  36. Franca, E., Alagapan, S., Pan, L., Varghese, K., Brewer, G.J. and Wheeler, B.C. Methodology and Characteristics of Micropatterned Neural Networks, BMES Meeting 2010, (October 9, 2010), Austin, TX
  37. Alagapan, S., Pan, L., Wheeler, B.C. and DeMarse, T., Validation of Granger Causality using Unidirectional Neuronal Networks, BMES Meeting 2010, (October 2010), Austin, TX
  38. Alagapan, S., Wheeler, B.C., DeMarse, T. Exploring Granger Causality As A Tool For Understanding Connectivity In Patterned Networks, MEA 2010 (7th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2010.
  39. Pan, L., Brewer, G.J., Wheeler, B.C. PDMS Microtunnels for MEA Recordings: Improvements in Mold Fabrication and Compatibility with Conventional MEAs, MEA 2010 (7th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2010.
  40. Brewer, GJ, Boehler, M, Wheeler, BC. NbActiv4 medium improvement to Neurobasal/B27 increases network activity which scales exponentially with synapse density MEA 2010 (7th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2010.
  41. Joag, C., Wheeler, B.C., DeMarse, T. Stimulation of MEA‘s inside Incubator MEA 2010 (7th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2010.
  42. Brewer, G.J., Boehler, M., Wheeler, B.C. MEA 2010 (7th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2010.
  43. Dworak, B, Varghese, K., Pan, L., Brewer, G.J., Wheeler, B.C. Creating Unidirectional Neural Networks on a Chip MEA 2010 (7th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2010.
  44. Ide, AN, Andruska, A, Boehler, M, Wheeler, BC, Brewer, GJ. Chronic network stimulation enhances evoked action potentials MEA 2010 (7th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, June 2010.
  45. Ide, AN, Andruska, A, Boehler, M, Wheeler, BC, Brewer, GJ. Chronic Network Stimulation Enhances Evoked Action Potentials, Soc. Neurosci. 2009.
  46. Musick, K and Wheeler, BC. Three-Dimensional Microelectrode Array for Recording Dissociated Neuronal Cultures. MEA 2008 (6th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, July 2008.
  47. Dworak BJ and Wheeler BC. Enhanced Extracellular Recordings from Axons Patterned through PDMS Microtunnels in a Neuronal Culture. MEA 2008 (6th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, July 2008.
  48. Brewer G, Boehler M, Jones T, Wheeler B. NbActiv4TM, a Novel Improvement to Neurobasal/B27TM Medium, Increases Activity in Neuronal Networks by Promoting Synaptogenesis. MEA 2008 (6th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, July 2008.
  49. Brewer G, Boehler, Pearson, R, DeMaris A, Wheeler, B. Neuron Network Activity Scales Exponentially with Synapse Density. MEA 2008 (6th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, July 2008.
  50. Brewer G, Boehler M, Wheeler B, Embryonic Hippocampal Cultures in NbActiv4TM Surpass Spiking Activity of Embryonic Cortical Cultures in either Serum Medium or NbActiv4TM. MEA 2008 (6th Int. Mtg., Substrate-Integrated Microelectrode Arrays), Reutlingen Germany, July 2008.
  51. Khatami DB, Brewer GJ, Wheeler BC, Effect of Short- and Long-term Electrical Stimulation on Network Behavior. MEA 2008 (6th Int. Mtg.,Substrate-Integrated Microelectrode Arrays),Reutlingen Germany, 2008.
  52. Jones, D.L., Lockwood, M.E., Feng , A.S., and Wheeler, B.C., Biologically Inspired Beamforming with small Acoustic Arrays, BIOSIGNALS 2008, Funchal/Madeira, Portugal, Jan 28-31, 2008.
  53. Khatami, D.B., Dworak B.J., Brewer, G.J., and Wheeler, B.C. Functional Connectivity Analysis and Tracking in Biological Neuronal Networks Patterned on Microelectrode Arrays. BMES Annual Fall Meeting, Los Angeles, CA., September 26-29, 2007.
  54. Dworak, B.J. Scharnweber, R.F., Musick, K.M., Khatami, D.B., Brewer, G.J., and Wheeler, B.C. Multi-compartment neural soma aggregates linked by electrically accessible 3-D axonal microchannels. BMES Annual Fall Meeting, Los Angeles, CA., September 26-29, 2007.
  55. Musick, K.M., and Wheeler, B.C. Three-dimensional microelectrode array for recording dissociated neuronal cultures, BMES Ann. Conf. Los Angeles, September 26-29, 2007.
  56. Wheeler, B.C., Engineering Form and Function in Cultured Neuronal Circuits, Medicon 2007, Ljubljana, Slovenia, June 2007.
  57. Kollmar, R, Vieira, M, Christensen, BL, Shah, SM, Kang, Y-J, Wheeler, BC and Feng, AS Promoting Neurite Outgrowth from Adult Spiral Ganglion Neuron, Age Related Hearing Impairment Conference, Antwerp, May 2007.
  58. Shah, SM, Christensen, BL, Kang, Y-J, Vieira, M, Wheeler, BC, Feng, AS, Kollmar, R. Expression of Frizzled Genes in the Inner Ear of Adult Mice. Abstract. Ann. Mtg. Assoc. Res. Otolaryng., Feb 2007.
  59. Cullen, DK, Vukasinovic, J, Irons, HR, Gleser, A, Wheeler, BC, and Laplaca, MC. Engineered high cell density three-dimensional constructs, Soc. Neurosci. Ann. Conf., Atlanta, Oct 2006.
  60. Wheeler, BC, Khatami, DB, Nam, Y, Boehler, MD, Brewer, GJ, Designed In Vitro Neuronal Networks: Dependency of Activity on Geometric Pattern, Biomedical Engineering Society Annual Meeting, Chicago, Oct 2006, featured presentation.
  61. Khatami, DB, Nam, Y, Wheeler, BC, Mapping Functional Connectivity in Geometrically Confined Neuronal Networks, Biomedical Engineering Society Annual Meeting, Chicago, Oct 2006.
  62. Brewer, GJ, Boehler, MD, Wheeler, BC, Higher activity with increased connections in patterned hippocampal neurons, Biomedical Engineering Society Annual Meeting, Chicago, Oct 2006.
  63. Brewer, GJ, Fogleman, CN, Boehler, MD, Wheeler, BC. (2006) Neural plasticity in hippocampal neurons by paired-pulse stimulation on MEA, International MEA Conference, Reutlingen Germany, July 2006.
  64. Brewer, G.J., Boehler, M.D., Wheeler, B.C. (2006) Higher activity with increased connections in patterned hippocampal neurons, International MEA Conference, Reutlingen Germany, July 2006.
  65. Brewer, G.J., Boehler, M.D., Wheeler, B.C., (2006) Added astroglia promote greater synapse density and higher activity in neuronal networks, International MEA Conference, Reutlingen Germany, July 2006.
  66. Musick, K., Nam, Y., Wheeler, B.C. (2006) Microstamped electrodes with PDMS insulator: A design towards inexpensive, single-use microelectrode arrays, International MEA Conference, Reutlingen Germany, July 2006.
  67. Khatami, D.B., Nam, Y., Wheeler, B.C. (2006) Tools for Automated Stimulation and Connectivity Analysis of Neuronal Networks Grown on Multielectrode Arrays, International MEA Conference, Reutlingen Germany, July 2006.
  68. Brown, E.A., Blum, R.A., Ross, J.D., Nam, Y., Wheeler, B.C., DeWeerth, S.P., (2006) An Integrated System for Simultaneous Multichannel Stimulation and Recording, International MEA Conference, Reutlingen Germany, July 2006.
  69. Kollmar, R., Vieira, R., Christensen, B., Wheeler, B., Feng, A., (2006) Survival and Stimulation of Neurite Outgrowth in a Serum-Free Culture of Adult Spiral-Ganglion Neurons. Ann. Mtg. Assoc. Res. Otolaryng., Feb, 2006, Baltimore MD.
  70. Scharnweber, R.F., Brewer, G.J., and Wheeler, B.C. (2005) Polarized Axon Growth of Hippocampal Neurons Cultured on Tapered Lines of Laminin, Soc. Neurosci. Ann. Conf., Wash. DC.
  71. Nam, Y., Brewer, G.J., Wheeler, B.C. (2005) Glial guidance by neurons in patterned hippocampal cultures in vitro. Soc. Neurosci. Ann. Conf., Wash DC.
  72. Vieira, M, Christensen; BL Wheeler, BC, Kollmar, R, Feng, AS. (2005). Survival and stimulation of neurite outgrowth in a serum-free culture of adult spiral-ganglion neurons, Soc Neurosci. Conf., Wash DC, Oct.
  73. Wheeler, BC (2005) Cultured neuronal networks: past, present, and future. BMES Ann Conf Baltimore.
  74. Wheeler, B.C. (2005) Enhancing neuron / electrode interfaces in culture. BMES Ann.Conf. Baltimore, Sept.
  75. Khatami,D.B., Brewer,G.J., Ujhelyi, E.,Wheeler, B.C. (2005) Bicuculline application enhances long-term activity in low density cultured hippocampal neurons, BMES Ann. Conf., Baltimore, Sept.
  76. Musick, K., Nam, Y., and Wheeler, B.C. (2005) Microstamp Patterned Electrodes with PDMS Insulator: Design for Inexpensive Microelectrode Arrays. BMES Ann. Conf. Baltimore, Sept.
  77. Wheeler, B.C. (2005) Starting a Bioengineering Department at the University of Illinois. Vietnam Bioeng. Conf. Ho Chi Minh City. July.
  78. Nam, Y., Wheeler, B.C., and Nam, M. H., Technological developments in studying neural information processing in patterned neuronal networks.
  79. Nam, Y. and Wheeler, B.C. Imaging locations of neurons vs. glia in low density culture, 2nd International IEEE EMBS Special Topic Conference on Neural Engineering, Washington DC, March 2005.
  80. Scharnweber, R.F., Brewer, G.J. and Wheeler, B.C., 2004, Cytochalasin treatment disrupts growth cone guidance on thin laminin lines in culture, Abstract, Society for Neuroscience Annual Meeting, San Diego CA Oct 2004.
  81. Khatami, D.B., Chang, J.C., Brewer, G.J., Wheeler, B.C, 2004, Effects of spatial confinement on the spontaneous and evoked activity of linearly patterned biological neural networks, Abstract, Society for Neuroscience Annual Meeting, San Diego CA Oct 2004.
  82. Brewer, G.J., Boehler, M.P., Nam, Y., Wheeler, B.C., 2004, Added astroglia increase spontaneous spiking, sensitivity to a GABA antagonist and to glutamate on multielectrode arrays in serum-free medium, Abstract, Society for Neuroscience Annual Meeting, San Diego CA Oct 2004.
  83. Nam, Y., and Wheeler, B.C., 2004, Micro-stencil based microelectrode array for neuronal cultures, Abstract, Biomedical Engineering Society Meeting, Oct. 2004, Philadelphia.
  84. Chen, H.C., and Wheeler, B.C., Evaluation of algorithms for displaying apparent connectivity in neuronal networks, Abstract, Biomedical Engineering Society Meeting, Oct. 2004, Philadelphia.
  85. Krishnan, B., and Wheeler, B.C., Evaluation of wavelet-based methods for spike sorting, Abstract, Biomedical Engineering Society Meeting, Oct. 2004, Philadelphia.
  86. Khatami, D.B., Nam, Y., Brewer, G.J., and Wheeler, B.C. Effect of bicuculline on the spontaneous and evoked activity of patterned embryonic hippocampal neurons cultured in vitro. EMBS Annual Conference, San Francisco, Sept 2004.
  87. Nam, Y., and B.C. Wheeler, Multichannel recording and stimulation of neuronal cultures grown on microstamped poly-D-lysine,EMBS Annual Conference, San Francisco, Sept 2004.
  88. Bruce C. Wheeler, Yoonkey Nam, and Gregory J. Brewer, Patterning to Influence in vitro Neuronal Interfaces, invited talk, EMBS Annual Conference, San Francisco, Sept 2004.
  89. Wheeler, B.C., Nam, Y., Khatami, Y., Scharnweber, R.F., Brewer, G.J., 2004, Patterned Neuronal Networks to Study Information Processing in vitro on Microelectrode Arrays,abstract, SIMEA 2004, Reutlingen Germany, July 6, 2004.
  90. Nam, Y., Wheeler, B.C. Neural recordings of dissociated hippocampal cultures using a 3D tip shaped microelectrode array, abstract, SIMEA 2004, Reutlingen Germany, July 6, 2004.
  91. Choi, Y., Seungkeun Choi, S., Powers, R., Nam, Y., Marr, A., Brewer, G.J., Wheeler, B.C., Allen, M.G., 2004, Three-Dimensional Tower Structures with Integrated Cross-Connects for 3-D Culturing of Neurons, poster, 2004 Solid-State Sensor and Actuator Workshop.
  92. Ratnam, R., Jones, D.L., Wheeler, B.C., and Feng, A.S., 2003, "Online estimation of room reverberation time," Journal of the Acoustical Society of America, vol. 113, p. 2269, 2003.
  93. Nam, Y., Khatami, D., Brewer, G.J., Wheeler, B.C., Spontaneous and Evoked Electrical Activity in Patterned, Cultured Neuronal Networks, Ann. Conf., Soc. Neurosci, New Orleans, Nov. 2003.
  94. Scharnweber, R.F., Nam, Y., Chang, J.C., Brewer, G.J., Wheeler, B.C., Technique for presenting multiple guidance cues to cultured embryonic rat hippocampal neurons, Ann Conf., Soc. Neurosci, New Orleans, Nov. 2003.
  95. Larsen, E., Lansing, C.R., O’Brien, W.D., Jr., Wheeler, B.C., Feng, A.S. Acoustic scene analysis using estimated impulse responses, 37th Asilomar Conf on Signals, Systems and Computers, Nov 6-9, Pacific Grove CA, 2003.
  96. Nam, Y., Khatami, D., Wheeler, B.C., and Brewer, G.J., Electrical stimulation of patterned neuronal networks in vitro, IEEE EMBS Annual Conference, Cancun, Mexico, October, 2003
  97. Mohan, S., Kramer, M.L., Wheeler, B.C., and Jones, D.L., Localization of nonstationary sources using a coherence test. IEEE Workshop on Statistical Signal Processing. September 2003.
  98. Nam, Y., Scharnweber, R., Chang, J.C. Wheeler, B.C., Brewer, G.J., A new MEA design approach for patterned neuronal circuits, poster presentation at SIMEA, Denton TX, May 2003.
  99. Khatami, D., Nam, Y., Wheeler, B.C., Neural characterization of spontaneous activity of spatially confined neuronal networks, poster presentation at SIMEA, Denton TX, May 2003.
  100. Nam, Y., Scharnweber, R., Khatami, D., Wheeler, B.C., Brewer, G.J. Neural networks in vitro – does function follow the form? Poster presentation at SIMEA, Denton TX, May 2003.
  101. Brewer, G.J., Wheeler, B.C. Enhanced synaptogenesis from nutrient support and neuron patterning on microelectrode arrays, presentation at SIMEA, Denton TX, March 2003.
  102. Nam, Y., Wheeler, B.C., Brewer, G.J., Electrical recordings with gold coated microelectrode arrays that permit alkanethiol control of neuronal attachment, IEEE EMBS Mtg, Houston TX, Oct 2002, on CD ROM
  103. Chang JC, Brewer GJ, Wheeler BC. An enhanced microstamping technique for controlled deposition of proteins. 2nd Annual International IEEE-EMBS Spec. Top. Conf. Microtechnologies in Medicine and Biology. Proceedings (Cat. No.02EX578). IEEE. 2002, pp.126-31. Piscataway, NJ, USA.
  104. B.C. Wheeler, "Designing In Vitro Patterned Neuronal Networks," invited presentation, 49th International Vacuum Society Meeting, Denver, CO, November 7, 2002.
  105. Nam, Y., Wheeler, B. C., and Brewer, G. J., "Electrical recordings with gold coated microelectrode arrays that permit alkanethiol control of neuronal attachment," IEEE EMBS Mtg, Houston, Oct 2002. On CD.
  106. Chang, J. C., Brewer, G. J., and Wheeler, B. C., "An enhanced microstamping technique for controlled deposition of proteins," [Conference Paper], 2nd Annual Int.l IEEE-EMBS Special Topic Conf. Microtechnologies in Medicine & Biology. Proc. Cat. No.02EX578, IEEE, Piscataway, NJ, 126-131, 2002.
  107. Nam, Y., Wheeler, B.C., Brewer, G.J. Gold surface microelectrode arrays permit geometrical control of neuronal networks via thiol linking chemistry, IEEE EMBS Spec. Top. Conf. On Microtechnologies in Medicine and Biology, Madison, WI, May 2-4, 2002.
  108. Nam, Y., Chang, J. C., Wheeler, B. C., Brewer, G. J., "Building Biological Neuronal Networks," presented at Cambridge Healthtech Conference BioMEMS & Biomedical Nanotechnology World 2001, Columbus Ohio, and at the NIH Neural Prosthesis Program Annual Meeting, Bethesda, MD, October, 2001.
  109. J. Larsen; Lockwood, M. E.; Lansing, C. R.; Bilger, R. C.; O'Brien, Jr., W. D.; Jones, D. L.; Wheeler, B. C.; and Feng, A.S., "Performance of a frequency-based minimum variance beamforming algorithm for normal and hearing impaired listeners," ASA Meeting, Chicago, IL 2001. Journal of the Acoustical Society of America, vol. 109, June, 2001.
  110. Berry, M. Lockwood, M.E., Jones, D.L., Bilger, R.C., Lansing, C.R., Liu, C., O'Brien, W.D., Wheeler, B.C. and Feng, A.S. (2001) Beamformer improvement with increasing number of sensors. J. Acoust. Soc. Am. 109, June, ASA Mtg., Chicago.
  111. Lockwood, M.E., Lansing, C.R., Bilger, R.C., O'Brien, W.D., Jones, D.L., Wheeler, B.C. and Feng, A.S. (2001). Performance of a frequency-based minimum variance beamforming algorithm for normal and hearing impaired listeners. J. Acoust. Soc. Am. 109, June, ASA Mtg., Chicago.
  112. Zheng, Y., Lockwood, M.E., Wheeler, B.C., Jones, D.L., Feng, A.S., O'Brien, W.D., Bilger, R.C., Lansing, C.R. (2001) Comparison of binaural beamformers for speech extraction in complex auditory scenes. J. Acoust. Soc. Am. 109, June, ASA Mtg., Chicago.
  113. Lockwood, M.E., Yang, K.L., Jones, D.L., Bilger, R.C., Lansing, C.R., Liu, C., O'Brien, W.D., Wheeler, B.C. and Feng, A.S. (2001) Robustness of the beamforming algorithms with head-related transfer functions. J. Acoust. Soc. Am. 109, June, ASA Mtg., Chicago.
  114. Lockwood, M.E., Elledge, M.E., Yang, K.L., Jones, D.L., Lansing, C.R., Bilger, R.C., Wheeler, B.C., O'Brien, W.D. and Feng, A.S. (2000) Simulation and real-time implementation of a new optimum beamforming technique. Intern. Hearing Aid Research Conference in Lake Tahoe (CA): 32-33.
  115. Yang, K.L., Lockwood, M.E., Elledge, M.E. & Jones, D.L. (2000) A comparison of beamforming algorithms for binaural acoustic processing. Proc. 9th IEEE Digital Signal Processing Workshop. Hunt (TX), Oct. 2000.
  116. Larsen, J., Lockwood, M.E., Lansing, C.R., Bilger, R.C., O'Brien, W.D., Jones, D.L., Wheeler, B.C. and Feng, A.S. (2001) Performance of a frequency-based minimum variance beamforming algorithm for normal and hearing impaired listeners. Abstr. 24th Annual Midwinter Meeting of the Assoc. Res. Otolaryngol., 174.
  117. Elledge, M.E., Lockwood, M.E., Bilger, R.C., Feng, A.S., Jones, D.L., Lansing, C.R. O'Brien, W.D. and Wheeler, B.C. (2000) Real-time implementation of a frequency-domain beamformer on the TI C62X EVM. Presented at 10th Ann. DSP Technol. Educ. & Res. Conf., Houston (TX), August 2-4.
  118. C. Henry, A. B. Kirillov, B. C. Wheeler, and H. W. Wiggins, Jr., "Spike Sorting Performance Metrics," conference paper, IEEE EMBS Meeting, Chicago, IL, July 2000. On CD ROM.
  119. D. W. Branch, B. C. Wheeler, G. J. Brewer, and D. E. Leckband, "Long-term Stability of Microstamped Substrates of Polylysine and Grafted Polyethylene Glycol in Cell Culture Conditions," conference paper, IEEE EMBS Meeting, Chicago, IL, July 2000. On CD ROM.
  120. M. E. Elledge; Lockwood, M. E.; Bilger, R. C.; Feng, A. S.; Goueygou; Jones, D. L.; Lansing, C. R.; Liu, C.; O'Brien, Jr., W. D.; and Wheeler, B. C., "A real-time dual-microphone signal-processing system for hearing aids," Journal of the Acoustical Society of America, vol. 106, Part 2, no. 2279A, 1999.
  121. Lockwood, M. E., Jones, D. L., Elledge, M. E., Bilger, R. C., Feng, A. S., Goueygou, M., Lansing, C. R., Liu, C. O'Brien, Jr., W. D., Wheeler, B. C., "A minimum variance frequency-domain algorithm for binaural hearing aid processing," ASA Meeting, Columbus OH, October 1999. Journal of the Acoustical Society of America, vol. 106, p. 2278, 1999.
  122. M. E. Lockwood, D. L. Jones, M. E. Elledge, R. C. Bilger, A. S. Feng, M. Goueygou, C. R. Lansing, C. Liu, W. D. O'Brien, Jr., and B. C. Wheeler, "A minimum-variance frequency domain algorithm for binaural hearing aid processing," ASA Meeting, Columbus OH, October 1999. Journal of the Acoustical Society of America, vol. 106, p. 2278, 1999.
  123. M. E. Elledge, M. E. Lockwood, R. C. Bilger, A. S. Feng, M. Goueygou, D. L. Jones, C. R. Lansing, W. D. O'Brien, Jr., and B. C. Wheeler, "A real-time dual-microphone signal processing system for hearing aids," ASA Meeting, Columbus OH, October 1999. JASA, vol. 106, p. 2279, 1999.
  124. Wheeler, B.C. (1999) “Micropattern neural networks in a dish,” invited talk, Cambridge Healthtech Institute Fourth Annual Conference on Microsystems Technology in Medicine and Biology, Boston MA.
  125. Venkateswar, R. A., Branch, D. W., and Wheeler, B. C. (1999) “A novel method for producing patterned biomolecule gradients,” Proc. IEEE EMBS 21st Annual Int. Conf., Atlanta, GA, October.
  126. Chang, J. C., Wheeler, B. C., and Brewer, G. J. (1999) “Substrate recording of patterned hippocampal neurons on multielectrode arrays,” Proc. IEEE EMBS 21st Annual Int. Conf., Atlanta, GA, October.
  127. Branch, D. W., Wheeler, B. C., Brewer, G. J. (1999) “Long-term maintenance of patterns of hippocampal pyramidal cells on substrates of polyethylene glycol and microstamped polylysine,” Proc. IEEE EMBS 21st Annual Int. Conf., Atlanta, GA, October.
  128. B. C. Wheeler, G. J. Brewer, D. W. Branch, J. Chang, and K. Venkateswar, "Rational Design Of In Vitro Neural Networks Using Patterned Self-Assembled Monolayers," American Chemical Society Abstracts, Los Angeles CA, March 1999.
  129. Lockwood, M.E., Jones, D.L., Elledge, M.E., Bilger, R.C., Feng, A.S., Goueygou, M., Lansing, C.R., Liu, C. O'Brien, W.D. Jr., Wheeler, B.C. (1999) A minimum variance frequency-domain algorithm for binaural hearing aid processing. J. Acous. Soc. Am. 106 (Pt. 2): 2278A.
  130. Elledge, M.E., Lockwood, M.E., Bilger, R.C., Feng, A.S., Goueygou, Jones, D.L., M., Lansing, C.R., Liu, C. O'Brien, W.D. Jr., Wheeler, B.C. (1999) A real-time dual-microphone signal-processing system for hearing aids. J. Acous. Soc. Am. 106 (Pt. 2): 2279A.
  131. Wheeler, B.C. (1998) “Multineuron Assemblies: Multidimensional Scaling For Visualization”, Symposium on Developments in Multichannel Extracellular Recording, U. Mich. Center for Neural Communication Technology, in conjunction with the 28th Soc. Neurosci. Conf., Los Angeles.
  132. Branch, D.W. Chang, J., Brewer, G.J., and Wheeler, B.C. (1998) “Micropatterned Neural Networks,” Abstr. 29th NIH Neural Prosthesis Conference Abstracts, 29, Bethesda MD.
  133. Wheeler, B.C., Brewer, G.J., and Branch, D.W. (1998) “Micropatterned Neural Networks,”Abstr. Biomed. Eng. Soc. Conf., Annals of Biomedical Engineering, 26, sup. 1, p. 93, Cleveland OH.
  134. Wheeler, B.C. (1998) “Multineuron Assemblies: Multidimensional Scaling For Visualization,” (invited presentation), Abstracts from the Int. Conf. on Substrate-integrated Microelectrode Arrays: Technology and Applications, p. 7, Natural and Medical Sciences Instititue at Tubingen in Reutlingen, Germany.
  135. Wheeler, B.C. (1998) “Microstamping Proteins For Precise Control Of Nerve Cell Growth In Culture,” (invited presentation), Abstracts from the Int. Conf. on Substrate-integrated Microelectrode Arrays: Technology and Applications, p. 45, Natural and Medical Sciences Instititue at Tubingen in Reutlingen, Germany.
  136. Wheeler B.C., & Brewer, G.J. (1998) “Microstamping proteins for precise control of nerve cell growth in culture,” Cambridge Healthtech Inst. Third Ann. Conf. Microsystems Techn. in Med. & Biol., Boston MA.
  137. Liu,C., Feng, A.S., O’Brien, W.D.,Jr., Wheeler,B.C., Bilger, R.C., & Lansing, C.R. (1997) “Improving the acuity and robustness of localization of multiple sources using ‘stencil’ filters,” JASA, 102(5), 3140.
  138. Liu, C., Feng, A.S., Wheeler, B.C., O'Brien, W.D., Bilger, R.C. & Lansing, C.R. (1997) “A binaurally-based auditory processor effectively extracts speech in the presence of multiple competing sounds,” Hearing Aid Research and Development Conference, NIH, Bethesda, MD.
  139. Corey, J.M., Branch, D.W., Wheeler, B.C., Weyhenmeyer, J.A. and Brewer, G.J. (1997) “Influencing polarity of hippocampal neurons using micro-stamp patterns of biomolecules,” Abstr. 27th Soc. Neurosci. Conf., 23, p. 32, New Orleans, LA.
  140. Branch, D.W., Corey, J.M., Wheeler, B.C., Weyhenmeyer, J.A. and Brewer, G.J. (1997) “Micro-stamp patterns of biomolecules for control of neuronal growth,” Abstr. 27th Soc. Neurosci. Conf., 23, p. 32, New Orleans, LA.
  141. Wheeler, B.C., Branch, D.W., Corey, J.M., Weyhenmeyer, J.A. and Brewer, G.J. (1997) “Engineering neural networks in vitro: microstamping biomolecules to control cell position,” Proc. IEEE EMBS 19th Annual Int. Conf., Chicago, IL.
  142. B. C. Wheeler and G. J. Brewer, "Microstamping Proteins for Precise Control of Nerve Cell Growth in Culture," Cambridge Healthtech Institute Third Annual Conference on Microfabrication Technology for Biomedical Applications, San Jose CA, October 1997.
  143. B. C. Wheeler, D. W. Branch, J. M. Corey, J. A. Weyhenmeyer, and G. J. Brewer, "Microstamping Proteins for Precise Control of Nerve Cell Growth in Culture," Abstract, 28th NIH Neural Prosthesis Conference Abstracts, Bethesda MD, p. 22, October 1997.
  144. Liu, C., Feng, A.S., Wheeler, B.C., O'Brien, Jr., W. D., Bilger, R.C., and Lansing, C., "Speech enhancement via directional hearing based on the 'place' theory," Second Biennial Hearing Aid Research & Development Conference, Washington DC, vol. 58A, no. II-P-29, September 1997.
  145. C. Liu, A. S. Feng, B.C. Wheeler, W. D. O'Brien, Jr., R. C. Bilger, and C. R. Lansing, "A binaurally-based auditory processor effectively extracts speech in the presence of multiple competing sounds," Hearing Aid Research and Development Conference, NIH, Bethesda, MD, September 1997.
  146. J. M. Corey, M. S. Chen, A. L. Brunette, D. W. Branch, J. A. Weyhenmeyer, B. C. Wheeler, and G. J. Brewer, "Influencing neuronal growth with multibiomolecule patterned substrates," 26th Society of Neuroscience Annual Conference, Washington, D.C., vol. 22, p. 1717, November 1996.
  147. Wheeler, B. C. (1996) "Universal access to ECE undergraduate information via the Web," IEEE Frontiers in Education Conference, Salt Lake City, UT, on CD ROM, November.
  148. Wheeler, B. C., Corey, J.M., Brunette, A.L., Chen, M.S., and Weyhenmeyer, J.A. (1996) "Micropatterning B104 neuroblastoma cells in culture: an assay for neuronal pattern synthesis", IEEE EMBS Annual Conference, Amsterdam, The Netherlands, on CD ROM.
  149. Wheeler, B. C., Chang, J. C., Berke, B. A., Corey, J. M. and Branch, D. W. (1996) "Technology for neuronal pattern synthesis and recording," Annals of Biomedical Engineering, p. S-68, v. 24, supplement 1, Fall 1996 Meeting, Biomed. Eng. Soc., University Park, PA.
  150. Wheeler, B. C., R. L. Magin, M. Osborne, and B. Bruce (1996) "A freshman general education bioengineering course on the world wide web," ASEE Annual Meeting, on CD ROM, Wash., D.C.
  151. Wheeler, B. C., R. L. Magin, M. Osborne, and B. Bruce (1996) "Asynchronous learning in the small engineering classroom," ASEE Annual Meeting, on CD ROM, Washington D.C., on CD ROM.
  152. Wheeler, B.C., Corey, J.M. and Brewer, G.J. (1995), “Micropatterning of neural growth in culture: A comparison of laser and photoresist based techniques,” 18th Mtg. Electrochem. Soc., Chicago, 1-8.
  153. J. M. Corey, B. C. Wheeler, and G. J. Brewer, "Confinement of hippocampal neurons to grid patterns using three silane-based photolithographic processes," Abstract, 26th NIH Neural Prosthesis Conference Abstracts, Bethesda, MD, p. 24, 1995.
  154. Corey, J.M., Wheeler, B.C. and Brewer, G.J., (1995) “Selective silane removal: A technique for micropatterning of neurons in culture,” 17th IEEE EMBS Conference, Montreal, 1995, 1731-1732.
  155. Bendre, A., Swain, R., Wheeler, B.C., & Greenough, W. (1995). Augmentation of cerebellar responses to parallel fiber activation following skilled motor acquistion in rats," Soc. Neurosci. Abstr. 21, San Diego, CA.
  156. Wheeler, B.C. (1995) “Multineuron assemblies: A generalized clustering approach,” International Workshop on Measures of Spatio-Temporal Dynamics, Bryn Mawr College.
  157. Corey, J. M., Wheeler, B.C., & Brewer, G. J. (1995). “Confinement of hippocampal neurons to grid patterns using three silane-based photolithographic processes,” NIH Neural Prosthesis Workshop, Bethesda MD.
  158. Wheeler, B.C. and Brewer, G.J., (1994), "Selective hippocampal neuritogenesis: axon growth on laminin or pleiotrophin, dendrite growth on poly-D-lysine", Soc. Neurosci. Abs., 20, p.1292, Miami Beach FL.
  159. Stavrakos, N. J., Wheeler, B. C., Gordon, S. H., Wicklow, D. T., Greene, R. V., & Schudy, R. B. (1994) “Identification of contaminated corn from FTIR spectra: A MATLAB tool for pattern recognition and neural network studies,” in C. H. Dagli,F. R. Fernandez,J. Ghosh, & R. T. S. Kumara (Ed.), Artificial Neural Networks in Engineering, 4 (779-784). St. Louis, MO.
  160. Wheeler, B. C. (1994). Visualizing multineuron assemblies a generalized clustering approach. In International Symposium on the Dynamics of Neural Processing, June (79-83). Washington D.C.
  161. Wheeler, B.C., Corey, J.M., and Brewer, G.J., (1993), "Patterned microcircuits of hippocampal neurons: comparisons of photoresist versus laser ablation processes," Soc. Neurosci Abstr. 19, p1292, Wash. DC.
  162. B. C. Wheeler, S. H. Gordon, D. R. DeWispeleare, M. A. Jackson, and R. V. Greene, "Neural network identification of contaminated corn from FTIR spectra," Proceedings of the IEEE EMBS 15th Annual International Conference, San Diego, CA, pp. 301-302, October 1993.
  163. Wheeler, B.C., Fang, L., Zardoshti, M., and Wiggins, H. (1993), "Multiple unit action potential sorting: investigation of features, algorithms, and parameters for a fully automated system," Proc. IEEE EMBS 15th Annual Int. Conf., 261-262.
  164. Peck, T.L., LaValle, L., Magin, R.L., Adesida, I., and Wheeler, B.C. (1993), "RF Microcoils with Micron-Scale Feature Sizes for NMR Microscopy," Proc. IEEE EMBS 15th Annual Int. Conf., 174-175.
  165. Zardoshti, M., Wheeler B.C., Badie, K. and Hashemi R., (1993) "Evaluation of EMG features for movement control of prostheses," Proc. IEEE EMBS 15th Annual Int. Conf., 1141-1142.
  166. Wiggins, H., Hetzel, G., Wheeler, B.C., and Lupescu, M., (1993) "Real-time sorting of neural action potentials one hundred channels at a time," NIH Neural Prosthesis Workshop, Bethesda MD, October.
  167. Wheeler, B.C., (1993), "Matlab exercises to demonstrate principles of biological modeling and signal processing," Proc. 100th Annual Conference ASEE, 1789-1790, Champaign IL.
  168. Wheeler, B.C. (1993), "Micropatterned neuronal cultures," Proc. 5th Iranian Biomed. Eng. Conf., Teheran.
  169. Wheeler, B.C. and Zardoshti, M., (1993), "Advances in neural spike sorting," Proc. 5th Iranian Biomedical Engineering Conference, Teheran.
  170. Ozdamar, O, and Wheeler, BC (1992) "Real-time processing of neurological signals: neuronal and EEG spike detection using digital signal processors," IEEE 14th Ann Int. Conf. IEEE EMBS, Paris, France, Nov.
  171. Wheeler, B.C. (1992), "Sorting action potentials one hundred channels at at a time," Proc. IEEE 14th Annual Int. Conf. IEEE EMBS, 1256-7 (invited paper).
  172. Fang, L., and Wheeler, B.C. (1992), "Sorting neural action potentials in extracellular recordings: a comparison of the effectiveness of popular sorting features," Proc. Comp. Nsci. Symp., Indianapolis.
  173. Zardoshti, M., and Wheeler, B.C. (1992), "Finding the number of neurons in extracellular recordings: a comparison of the effectiveness of popular clustering indices," Proc. Comp. Nsci. Symp., Indianapolis.
  174. Smith, S.R., Wheeler, B.C., Dowd, J.P., and Comer, C.M., (1991), "Investigation of multi-cellular neural code for directed movement," IEEE EMBS Conf., Orlando.
  175. Corey, J.M., Wheeler, B.C., and Brewer, G.J., (1991), "Localization of hippocampal neurons to chemically modified silicon nitride surfaces," Soc. Neurosci. Abstr., 17, p. 210, New Orleans.
  176. Wheeler, BC, Boppart, SA, and Wallace, C, "A flexible, perforated microelectrode array for extended neural recordings," 21st Society of Neuroscience Conference, New Orleans, LA, vol. 17, p. 175, November 1991.
  177. Wheeler, B.C. (1991), "Multi-unit neural recording," Abstr. Biomed. Eng. Soc. Conf., Annals of Biomedical Engineering, 19, 622, Charlottesville.
  178. Boppart, S., Wheeler, B.C., and Wallace, C. (1991), "A flexible, porous electrode array improves longevity in hippocampal slice recordings," 14th Midwest Neuroscientists Conf., Urbana IL.
  179. Corey, J.M., Wheeler, B.C., and Brewer, G.J. (1990), "Compliancy of hippocampal neurons grown on patterned microcircuits," Soc. Neurosci. Abstr., 16, p. 1008, St. Louis.
  180. Wheeler, B.C., Eden, G.J., and Brewer, G.J. (1989), "Patterned growth of hippocampal neurons on microcircuits," Soc. Neurosci. Abstr., 15, p. 1036, Phoenix AZ.
  181. Brusnighan, D.A., Strauss, M.G., Floyd, J.M., and Wheeler, B.C., (1989) "Orientation aid implementing the global positioning system," Proc. NE Bioeng. Conf., Boston.
  182. Dowd, J.P., Smith, S.R., Comer, C.M., and Wheeler, B.C. (1988), "Multi-unit analysis of a neural ensemble controlling directed movement," Soc. Neurosci. Abstr., 14, p. 689, Toronto.
  183. Smith, S.R., Dowd, J.P, Wheeler, B.C., and Comer, C.M. (1988), "Analysis of multiunit data from a neural ensemble controlling directed movement," Proc. 10th IEEE EMBS Conf., 1171-1172, New Orleans, LA.
  184. Willming, D.A. and Wheeler, B.C. (1988), "A real-time multichannel DSP-based neural signal analysis system," Proc. 10th IEEE EMBS Conf., 1169-1170, New Orleans, LA.
  185. Wheeler, B.C. and Tang, B. (1988), "A flexible electrode array for brain slice recording," Proc. 10th IEEE EMBS Conf., 816-817, New Orleans, LA.
  186. Wheeler, B.C. and Smith, S.R. (1988), "Neural network models of an escape response," Neural Networks, 1 (Suppl. 1), 281.
  187. Wheeler, BC, "Personal computer based multiunit and multichannel neural data acquisition," 3rd Symposium on Networks in Brain and Computer Architecture, Denton, TX, 1987.
  188. Novak, J.L., Wheeler, B.C., and Chang, F.-L. (1987), "Variations in the delays between peaks within population bursts in CA1 recorded with a 32 element array," Soc. Neurosci. Abstr., 13, 942, New Orleans.
  189. Wheeler, B.C. and Smith, S.R. (1987), "Action potential waveform alignment with cubic splines," Proc. 9th IEEE EMBS Conf. 1852-3, Boston, MA.
  190. Novak, J.L. and Wheeler, B.C. (1986), "Epileptiform activity recorded from the rat hippocampal slice with a planar microelectrode array," Soc. Neurosci. Abstr., 12, p. 1528, Washington, DC.
  191. Smith, S.R. & Wheeler, B.C. (1986), "A digital, real-time action potential detection system," Proc. 8th IEEE EMBS Conf., 259-262, Fort Worth, TX.
  192. Wheeler, B.C. and Novak, J.L. (1986), "Current Source Analysis of Brain Slice Electrode Array Data", Proc. 8th IEEE EMBS Conf., 458-460, Fort Worth, TX.
  193. Wheeler, B.C., Novak, J.L., and Smith, S.R. (1986), "32 channel microelectrode array recordings from brain slices," Proc. 19th ACEMB, 327, Baltimore, MD.
  194. Smith, S.R. & Wheeler, B.C. (1985), "Neural signal detection techniques: performance for real-time applications", Proc. 7th IEEE EMBS Conf., 1274, Chicago, IL.
  195. Novak, J.L. and Wheeler, B.C. (1985), "Multi-site stimulation and recording from rat hippocampal slices using a microelectrode array," Proc. 7th IEEE EMBS Conf., 1275, Chicago, IL.
  196. Picus, M.M. and Wheeler, B.C. (1983), "A nine channel probe for multiple neuron recording," Proc. 36th ACEMB, 224, Columbus OH.
  197. Wheeler, B.C. and Heetderks, W.J. (1980), "Performance of algorithms for the detection and classification of waveforms from individual neurons," Workshop Dig. Sign. & Waveform Anal., 5th Int. Conf. Patt. Recog., Miami Beach.
  198. Wheeler, B.C. and Heetderks, W.J. (1980), "The effects of sampling rate on the signal-to-noise ratio of biological signals," Proc. 8th New Eng. Bioeng. Conf., 446-450, Cambridge MA.
  199. Wheeler, B.C. and Heetderks, W.J. (1979), "Separation of cockroach giant axon action potentials using multiunit analysis techniques," Proc. 7th New Eng. Bioeng. Conf., 310-313, Troy NY.
  200. Kim, M., Shin, K.G., and Wheeler, B.C. (1978), "A systems model of cell kinetics and its application to cancer chemotherapy," Proc. Joint Automatic Control Conf.
Other Conference and Workshop Presentations (unpublished)
  1. Microstamping Proteins for Precise Control of Nerve Cell Growth in Culture, Bruce C. Wheeler, Darren W. Branch, Joseph M. Corey, James A. Weyhenmeyer and Gregory J. Brewer, Conference on Microfabrication for Biotechnology, San Jose CA, October 27, 1997.
  2. Artificial Patterning of the Growth of Neurons: a Beginning Technology, Lecture to Spinal Cord Injury Center, Amirkabir University, Tehran, Iran, Jan. 6, 1993.
  3. Technology for Recording from Many Individual Neurons, Tutorial, 5th Annual Iranian Biomedical Engineering Conference, Tehran, Iran, Jan. 5-7, 1993.
  4. H. Wiggins, G. Hetzel, B. C. Wheeler, and M. Lupescu, "Real-time sorting of neural action potentials one hundred channels at time," 24th Annual Neural Prosthesis Workshop, Bethesda, MD, October 13-15, 1993.
  5. NCSA Workshop on Real-Time Applications of High Performance Computing for Biological Imaging, Urbana, IL. , September 1993. (Poster authors: B. C. Wheeler, M. Lupescu, G. Hetzel, and H. Wiggins)
  6. Ozdamar, O., and Wheeler, B.C., (1992), "Real-time processing of neurological signals: neuronal and EEG spike detection using digital signal processors", invited tutorial, IEEE EMBS Ann. Conf. (Paris, France)
  7. Multineuron Patterning and Recording, ONR Conference on Controlled Growth and Communication in Cultured Mammalian Neurons, Elkridge, MD, April 27, 1992.
  8. Techniques for Patterning Hippocampal Neurons in Culture, Midwest Hippocampal Mtg. Urbana, July 10, 1992.
Invited Lectures and Presentations – Science and Engineering
  1. Exploring Brain Dynamics with In Vitro Neuronal Networks. IEEE San Diego Section Meeting in conjunction with IEEE BRAIN Workshop. Nov 10, 2016.
  2. Reverse and Forward Engineering of the Brain / New Technologies for In Vitro Neural Systems, Primer Encuentro De Ingeniería Biomédica, Pontificia Universidad Católica del Perú, Lima, Peru, Nov 26, 2014.
  3. Cultured Neural Networks: From Patterns to Circuits with Information Transfer, IEEE Chapter Meeting, Lima Peru, Nov 25, 2014.
  4. Exploring Brain Dynamics with In Vitro Neuronal Networks. IEEE EMBS BRAIN Grand Challenges Conference, Washington DC, Nov 14, 2014.
  5. Cultured Neural Networks: From Patterns to Circuits with Information Transfer, invited department talk, , Favaloro University, Buenos Aires, Oct 27, 2014.
  6. Cultured Neural Networks: From Patterns to Circuits with Information Transfer, plenary speaker, Medical and Biological Engineering Conference (MBEC 2014), Dubrovnik, Slovakia. Sep 8, 2014.
  7. Cultured Neural Networks: From Patterns to Circuits with Information Transfer, Cultured Neural Networks: From Patterns to Circuits with Information Transfer, University of Central Florida NanoScience Technology Center. May 9, 2014.
  8. Reverse and Forward Engineering of the Brain. Shanghai Jiao Tong University. Dec 21, 2013.
  9. Brain on a Chip: From Patterns to Circuits with Information Transfer, Shanghai Jiao Tong University. Dec 20, 2013.
  10. Brain on a Chip: From Patterns to Circuits with Information Transfer Reverse and Forward Engineering of the Brain, including Brain on a Chip. Shanghai University. Dec 20, 2013.
  11. Reverse and Forward Engineering of the Brain, including Brain on a Chip. Zhejiang University. Dec 19, 2013.
  12. Brain on a Chip: From Patterns to Circuits with Information Transfer, invited keynote, 2013 6th International Conference on BioMedical Engineering and Informatics (BMEI 2013), Hangzhou China. Dec 17, 2013.
  13. Reverse and Forward Engineering of the Brain IEEE Grand Challenge in Life Sciences. Singapore. Dec 2-4, 2013.
  14. Brain on a Chip: Can We Build One? Presentation to the IEEE EMBS San Diego Chapter, June 26, 2013.
  15. Cultured Neural Networks: From Patterns to Circuits with Information Transfer, 4th US-Turkey Advanced Study Institute on Global Healthcare Challenges. Antalya. June 20, 2013.
  16. Brain on a Chip: Designing In Vitro Neural Circuits, Seminar, Univ. Houston, Biomed Eng. Dept., Mar 25, 2013.
  17. Can We Forward Engineer a Living Brain? Advances in Neural Culture Technology. Graduate Seminar, Tulane University, Nov 1, 2012.
  18. Can We Forward Engineer a Living Brain? Advances in Neural Culture Technology. Shenzhen University, Oct 19, 2012.
  19. Can We Forward Engineer a Living Brain Advances in Neural Culture Technology. Chinese University of Hong Kong, Oct 18, 2012.
  20. Advances in Neural Culture Technology Invited Keynote Lecture. 5th International Congress on Image and Signal Processing (CISP 2012) and 5th International Conference on BioMedical Engineering and Informatics (BMEI 2012), Chongqing, China, October 16, 2012.
  21. Grand Challenge in Neural Engineering: Can We Forward Engineer a Living Brain? Keynote Lecture, Chinese National Biomedical Engineering Conference, Guilin, China. Oct 13, 2012
  22. Can We Forward Engineer a Living Brain? Advances in Neural Culture Technology Invited Keynote Lecture. World Congress on Medical Physics and Biomedical Engineering, Beijing, China, May 25, 2012. Not given for health reasons.
  23. Designing Neural Circuits In Vitro. Invited Keynote Speaker. Neuroprosthetics 2012. Worcester Polytechnic Institute, Worcester MA. Feb 23, 2012.
  24. Grand Challenge in Neural Engineering: Can We Forward Engineer a Living Brain? BME Department Seminar, Tsinghua University, Beijing, China, Jan 10, 2012.
  25. Grand Challenge in Neural Engineering: Can We Forward Engineer a Living Brain? Invited Keynote Lecture. Int. Conf. Biomed. & Health Informatics, Shenzhen, China, Jan 4, 2012.
  26. Brain on a Chip: Can We Build One? Seminar, School of Health Engineering. Arizona State University, Dec 16, 2011.
  27. Enhanced Neural Culture Recording from MEAs Using Microtunnels, Liangbin Pan, Bruce Wheeler. Satellite Event, 41st Annual Meeting, Soc. For Neuroscience, Nov. 14, 2011. Presentation delivered by Liangbin Pan.
  28. Brain on a Chip: Can We Build One? Presentation to the US Turkey Advanced Study Institute on Global Health Care Challenges. Antalya, Turkey. July 19, 2011.
  29. Brain on a Chip: Can We Build One? Seminar. Biomedical Engineering Dept. Illinois Institute of Technology, Feb 4, 2011.
  30. Brain on a Chip: Can We Build One? IEEE International Conference on Information Technology and Applications in Biomedicine (ITAB 2010), Corfu Greece, November 3-5, 2010.
  31. Brain on a Chip: Can We Build One? Packaging Center, Binghamton University, May 19, 2010.
  32. Brain on a Chip: Can We Build One? Electrical Engineering Dept., Seoul National University, May 16, 2010.
  33. Brain on a Chip: Designing Neural Networks in Culture. Keynote Speaker. Korean Biomedical Engineering Society Meeting on Future Neurotechnologies for Neuron, Network and Brain, Seoul, May 13, 2010.
  34. Can We Forward Engineer a Living Brain? Featured Speaker. IEEE EMBS Forum on Grand Challenges in Neuroengineering, Bethesda MD May 7-8, 2010.
  35. Brain on a Chip: Can We Build One? Center for Exercise Science, University of Florida, Jan 14, 2010.
  36. Brain on a Chip: Can We Build One? ISABEL 2009 (bioengineering conference), Bratislava, Slovakia, November 24, 2009.
  37. Brain on a Chip: Can We Build One? Los Alamos National Laboratory, February 27, 2009.
  38. Faculty for “Neuro-Electronic Hybrid School, Institute for Advanced Studies, the Hebrew University of Jerusalem, Israel, March 15-20, 2009. Invited but withdrew for health reasons.
  39. Brain on a Chip: Progress in its Design and Construction", Workshop on Nanotechnology as an Enabler for Neuroscience, Neuroengineering and Neural Prostheses, Stanford University, Dec 11, 2008.
  40. Brain on a Chip: If We Build One, What Will It Say? Distinguished Lecture Series, invited talk, Institute for Computing, Information and Cognitive Systems, University of British Columbia, October 23/24, 2008.
  41. Brain on a Chip. U Florida Biomedical Engineering Dept Seminar, Sept 2009.
  42. Brain on a Chip: Can We Build One? IEEE EMBS Annual Conference, Neural Engineering Symposium, Vancouver, British Columbia, Aug 2008.
  43. Brain on a Chip: Can We Build One? ECE Dept., Southern Methodist University, April 30, 2008.
  44. Brain on a Chip: Can We Build One? Brain and Bio Engineering Department, KAIST, November 14, 2007.
  45. Biologically inspired binaural hearing aid algorithms: Design principles and effectiveness, Seoul National University, November 13, 2007
  46. Brain on a Chip: Can We Build One? Seoul National University, November 12, 2007.
  47. Brain on a Chip: Can We Build One? Biomedical Engineering Department, Yale University, Oct. 18, 2007.
  48. From Engineered Neural Networks to Biologically Inspired Hearing Aids, Samples of Bioengineering and Neural Engineering Research, University of New Mexico, Sept. 13, 2007.
  49. Brain on a Chip: Can We Build One? Tutorial, Workshop on Advances in Cognitive and Neural Engineering, IEEE EMBS Conf, Lyon, August 2007.
  50. Brain on a Chip: An Engineer's Challenge, ECE Department seminar, Univ. New Mexico, June 19, 2007.
  51. Brain on a Chip: Can We Build One? Plenary Address, IEEE Neural Engineering Conf., Hawaii, May 2007.
  52. Brain on a Chip: An Engineer's Challenge, Department seminar, Michigan State University, April 5 2007.
  53. Engineering Form & Function in Cultured Neuronal Networks, Univ. Central Florida, March 22, 2007.
  54. Engineering Form & Function in Cultured Neuronal Networks, Department of Biomedical Engineering Department, University of Florida, March 20, 2007.
  55. Engineering Form and Function in Cultured Neuronal Networks, Department seminar, Department of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, March 16, 2007.
  56. Brain on a Chip: An Engineer's Challenge. Colloquium Speaker, Electrical and Computer Engineering Department, Montana State University, Jan 26, 2007.
  57. Engineering Form and Function in Cultured Neuronal Circuits, Bioengineering Department Seminar, UC Irvine, January 25, 2007
  58. Engineering Form and Function in Cultured Neuronal Circuits, Workshop on the Frontiers in Quantum and Biological Information Processing, U. Central Florida, Orlando, Nov 17, 2006.
  59. Progress and Challenges for Engineering Form and Function in Cultured Neuronal Networks, Bioengineering Department Seminar, Penn State University, Nov 3, 2006.
  60. An Introduction to the Use of Microelectrode Arrays, invited talk, International MEA Conference, Reutlingen Germany, July 2006. (not delivered due to emergency)
  61. Engineering Form and Function in Cultured Neuronal Circuits, University of Texas at Dallas, June 26, 2006. (not delivered due to emergency)
  62. Progress and Challenges for the Engineering Design of In Vitro Neuronal Networks, Duke University, Biomedical Engineering Dept., June 20, 2006.
  63. Engineering Form and Function in Cultured Neuronal Networks, Bioeng. Dept., U. Utah, Apr 28, 2006.
  64. Engineering Cultured Neuronal Networks. University of Louisville School of Medicine, Neuroscience Department Seminar, Jan 26, 2006.
  65. Engineering Cultured Neuronal Networks. Center for Nano Science and Technology, U Illinois, Nov 2, 2005.
  66. Engineering Cultured Neuronal Networks. Biocomplexity Institute, University of Indiana, Oct. 4, 2005.
  67. Advances in Neural Interfaces From In Vitro Models, Neural Interfaces Workshop, Bethesda, Sept 9, 2005.
  68. Cultured Neuronal Networks: Design, Function, Interfaces, Analyses. Presentation to the Bioengineering and Bioinformatics Summer Institute, Clemson University, June 30, 2005.
  69. Cultured Neuronal Networks: Design, Function, Interfaces, Analyses. Presentation to Bioelectrode Interfaces Short Course, University of Illinois at Chicago, June 3, 2005.
  70. Micropatterned Neuronal Networks in Culture: Simplicity or Complexity? Invited talk, 5th Understanding Complexity Symposium, Department of Physics, University of Illinois at Urbana-Champaign, May 17, 2005
  71. Cultured Neuronal Networks: Design, Function, Interfaces, Analyses. Invited talk, Bioengineering Department, University of Minnesota, Feb 28, 2005.
  72. Patterning to Enhance Activity of Cultured Neuronal Networks. Invited Talk. Indiana University Purdue University at Indianapolis, November, 2004.
  73. Patterning to Enhance Activity of Cultured Neuronal Networks. Invited Talk. Bioengineering Department, University of California at San Diego, October 22, 2004.
  74. Patterning to Influence in vitro Neuronal Interfaces, Bruce C. Wheeler, Yoonkey Nam, and Gregory J. Brewer, invited talk, EMBS Annual Conference, San Francisco, Sept 2004.
  75. Cultured Neuronal Networks: Design, Function, Interfaces, Analyses. Invited talk, Bioengineering Department, Arizona State University, April 2, 2004.
  76. Patterning to Enhance Activity of Cultured Neuronal Networks. Invited Talk. Biomedical Engineering Department, Northwestern University, Mar. 11, 2004.
  77. Multineuron Assemblies: Multidimensional Scaling For Visualization, invited talk, Center for Computational biology, Montana State University, Bozeman MT, January 16, 2004.
  78. Patterning to Enhance Cultured Neuronal Networks. Invited talk, Center for Computatonal Biology, Montana State University, Bozeman MT, January 16, 2004.
  79. Cultured Neuronal Networks: Design, Function and Interfaces. Invited talk, Fifth International Workshop on Future Information Processing Technologies, Miyazaki, Japan, November 11, 2003.
  80. Patterning to Enhance Activity of Cultured Neuronal Networks, invited talk, Cornell University Nanofabrication Center, October 28, 2003.
  81. Patterning to Enhance Activity of Cultured Neuronal Networks, invited talk, Annual Provost’s Neuroscience Symposium, University of Southern California, October 9, 2003.
  82. Patterning to Enhance Activity of Cultured Neuronal Networks, invited talk, School of Engineering, University of California at Santa Cruz, August 21, 2003.
  83. Taking Neurons to the Electrode, invited talk to the Asilomar Conference on Implanted Auditory Prostheses, Pacific Grove CA, August 20, 2003.
  84. Patterning to Enhance Activity of Cultured Neuronal Networks, invited talk at Session on Neural Engineering at Gordon Conference on Biomaterials: Biocompatibility & Tissue Engineering, July 20-25, 2003.
  85. Patterning to Enhance Activity of Cultured Neuronal Networks, invited presentation at workshop on Nonlinear Dynamics, Control and Guidance of Unmanned Autonomous Vehicles (UAV), ONR and University of Florida, Gainesville, May 29, 2003.
  86. Neurons on Chips as Signaling and Control Devices, tutorial presentation at workshop on Nonlinear Dynamics, Control and Guidance of Unmanned Autonomous Vehicles (UAV), ONR and University of Florida, Gainesville, May 29, 2003.
  87. Designing In Vitro Patterned Neuronal Networks, seminar, Biomedical Engineering Department, University of Twente, Netherlands, May 20, 2003.
  88. Patterning to Enhance Activity of Cultured Neuronal Networks, invited talk at Workshop on Biology and Physics at Interfaces: From Single Molecules to Cells, Research Center at Julich, Germany, May 21, 2003.
  89. Designing In Vitro Patterned Neuronal Networks, invited seminar, BioEngineering Department, RPI, Troy NY, March 24, 2003.
  90. Designing In Vitro Patterned Neuronal Networks, invited seminar, Chemical Engineering Department, University of California at Santa Barbara, Feb 20, 2003.
  91. Biologically inspired binaural hearing aid algorithms: Design principles and effectiveness. Invited talk, McMaster-Gennum Workshop on Intelligent Hearing Instruments, Kimberley, Ontario, Canada, Oct 1, 2002.
  92. Designing In Vitro Patterned Neuronal Networks, invited seminar, Bioengineering Department, Case Western Reserve University, Cleveland OH Sept 20, 2002.
  93. Designing In Vitro Patterned Neuronal Networks, invited talk, 60th Device Research Conference, Emerging Technologies Session, June 24, 2002.
  94. Designing In Vitro Patterned Neuronal Networks, invited talk, Bioeng Dept, U. Southern Cal., June 25, 2002.
  95. Designing In Vitro Patterned Neuronal Networks, invited talk, Rutgers University Bioengineering Department, April 1, 2002.
  96. Designing In Vitro Patterned Neuronal Networks, invited talk, Complex Systems Symposium, University of Illinois, Urbana, May 14, 2002.
  97. Designing In Vitro Patterned Neuronal Networks, invited talk, Materials Research Society Annual Conference, Boston, November 26, 2001.
  98. Rational Design of Neural Networks with Real Neurons, graduate seminar, Bioengineering Department, Penn State University, State College PA, Nov 8, 2001.
  99. Novel Algorithms for Binaural, Directionally Selective Microphones for Hearing Aid Applications, graduate seminar, Bioengineering Department, Penn State University, State College PA, Nov 8, 2001.
  100. Designable Neuronal Networks in Vitro, invited dinner symposium technical talk, Conference on Artificial Neural Networks In Engineering (ANNIE 2001), St. Louis, MO, Nov 6, 2001.
  101. Surface Micro-Nanotech Symposium Chair, BioMEMS and Biomedical Nanotechnology Conference, Columbus Ohio, September 22-25, 2001.
  102. Progress toward the Design of In Vitro Neural Networks, invited talk, Conference on Assembly and Self-Assembly at the Interface of Biology, Chemistry and Physics, Il Ciocco, Italy, Aug. 20-25, 2001.
  103. Progress and Challenges for the Design of In Vitro Neural Networks, International Workshop on Cell-Substrate Coupling, Munich, Germany, June 2001.
  104. Rational Design of Neural Networks, seminar to the Max Planck Institute for Polymer Research, Mainz, Germany, March 20, 2001.
  105. Microcontact Printing of Biomolecules on Glassy Substrates, lecture to Samsung Central Research Laboratory, Seoul Korea, Feb 9, 2001.
  106. Neural Signal Processing Techniques, II. Tutorial to the Nano-Bio Engineering Research Center Workshop, Seoul National University, Korea, Feb 9, 2001.
  107. Neural Signal Processing Techniques, I. Tutorial to the Nano-Bio Engineering Research Center Workshop, Seoul National University, Korea, Feb 8, 2001.
  108. Rational Design of Neural Networks with Real Neurons, lecture to the Nano-Bio Engineering Research Center Workshop, Seoul National University, Korea, Feb 5, 2001.
  109. Micropatterned Neural Networks in a Dish, graduate seminar, Dept. of Bioengineering, Clemson University, Dec. 8, 2000, Clemson SC
  110. Rational Design of Neural Networks in Vitro by Micropatterning, IEEE Solid State Circuits and Technology Workshop on Biomedical Electronics, October 12, 2000, Arlington VA
  111. Micropatterned Neural Networks in a Dish, seminar to Johns Hopkins University Department of Bioengineeirng, Sept 22, 2000, Baltimore MD.
  112. Hybrid Systems, talk to NSF Workshop on Biocomputation, Sept 21, 2000, Arlington VA
  113. Biological/Electronic Interface Panel Presenter, NIH BECON Symposium on Nanoscience and Nanotechnology: Shaping Biomedical Research, Bethesda MD, June 25-26, 2000.
  114. Patterned Neural Networks in a Dish. Seminar at University of Illinois at Chicago. February 2, 2000.
  115. Neural Networks in a Dish, Southern Illinois University, Springfield, Jan 19, 1999.
  116. Micropatterned Neural Networks in a Dish. invited talk, Cambridge Healthtech Institute Fourth Annual Conference on Microsystems Technology in Medicine and Biology, Boston MA, December 3, 1999.
  117. Cochlear Prostheses. Seminar at University of Illinois at Chicago. November 29, 1999.
  118. Multiple Neuron Signal Processing: Spike Sorting and Multidimensional Scaling For Visualization,Seminar to the Inter-University Semiconductor Research Center, Seoul National University, Seoul Korea, Sept, 1999.
  119. Applications of Cellular Microlithography: The Creation of a Neural Network in a Culture Dish. Seminar to the Korea Advanced Institute for Science and Technology (KAIST), Taejon, Korea, Sept., 1999.
  120. Applications of Cellular Microlithography: The Creation of a Neural Network in a Culture Dish. Seminar to the Inter-University Semiconductor Research Center, Seoul National University, Seoul Korea, Sept., 1999.
  121. Microstamping Deposition for Patterned Nerve Cell Culture. Cambridge HealthCare Institute Conference on Microsystems Technology in Medicine and Biology, Boston MA, April 16, 1998.
  122. Micropatterned Neuronal Networks, Workshop on Novel Applications of VLSI Methodology, Defense Sciences Research Council, LaJolla CA, July 23, 1997.
  123. Can We Use Neural Networks to Understand Neural Networks? Neural Spike Waveform Separation and the Understanding of Multiple Spike Trains, Physiology Department, Northwestern University, Chicago, IL June 18, 1993.
  124. Signals, Sensors, and Structures for Neural Pattern Analysis, Sangamon County Chapter of the Society for Neuroscience, Southern Illinois University, Springfield, IL, December 15, 1992.
  125. Microelectrode Arrays for Neuroscience, Delaware State College, Minority Access to Research Careers Seminar, March 20, 1992
Invited Lectures and Presentations – Health Informatics and EMBS
  1. Visions on Biomedical and Health Informatics. KAIST Bio and Brain Engineering Department, October 26, 2016 (Daejon, Korea).
  2. Visions on Biomedical and Health Informatics. U Southern California, April 25, 2016.
  3. Panel Member, NIH-IEEE Strategic Conf. Healthcare Innovations and Point-of-Care Technologies for Precision Medicine, Bethesda MD, Nov 10, 2015.
  4. IEEE-EMBS Visions and American Perspectives in Health Informatics. Int’l Conf. Biomed & Health Informatics (ICBHI15), Hainan, China Oct 9, 2015.
  5. IEEE-EMBS Visions and American Perspectives in Health Informatics. Keynote Presentation. VI Congreso Latinoamericano de Ingeniería Biomédica CLAIB 2014. Parana Argentina October 29, 2014.
  6. IEEE-EMBS Visions and American Perspectives in Health Informatics. Symposium presentation. IEEE Engineering in Medicine and Biology Annual Conference, Chicago, August 26, 2014.
  7. Biomedical and Health Informatics: Prospects for the Future and the Future of Our Students. The view from IEEE EMBS. IEEE EMBS Special Topic Conference on Biomedical and Health Informatics. Keynote speaker. Valencia Spain, June 2, 2014.
  8. Biomedical and Health Informatics: Prospects for the Future and the Future of Our Students. The view from IEEE EMBS. 13th IEEE International Conference on Bioinformatics and Bioengineering, Special Symposium on Health Informatics, 2013 6th International Conference on BioMedical Engineering and Informatics (BMEI 2013), Hangzhou China. Dec 17, 2013.
  9. Biomedical and Health Informatics: Prospects for the Future and the Future of Our Students. The view from IEEE EMBS. 13th IEEE International Conference on Bioinformatics and Bioengineering, Chania, Crete, Greece, Nov 11-13, 2013.
  10. Biomedical and Health Informatics: Prospects for the Future and the Future of Our Students. The view from IEEE EMBS. International Conference on Health Informatics. Vilamoura Portual. Nov 9, 2013.
  11. Panel Member, IEEE EMBS Special Topic Conference on Point-of-Care Healthcare Technologies, Bangalore India, Jan 18, 2013
Invited Lectures and Presentations – Scientific Writing; Journal Editorship
  1. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? Grad Seminar U Southern California, April 25, 2016.
  2. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? IEEE EMBS Conference on Biomedical and Health Informatics, Valencia, Spain, June 3, 2014.
  3. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? Shanghai Jiao Tong University, Dec 21, 2013.
  4. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? Hangzhou Normal University, Dec 19, 2013.
  5. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? Shenzhen University, Oct 19, 2012.
  6. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? Chinese University of Hong Kong, Oct 18, 2012.
  7. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? BMEI’12-CISP’12, Chongqing, China, Oct 15, 2012.
  8. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? Chinese National Biomedical Engineering Conference, Guilin China. Oct 13, 2012.
  9. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? IEEE Eng. Med. Biol. Conf, San Diego, Aug 31, 2012.
  10. Writing and Reviewing Scientific Papers: Redundant Publication. World Congress on Medical Physics and Bioengineering, Beijing, May 25, 2012. Not given, health reasons.
  11. Tips for Scientific Writing and What Editors and Reviewers Are Looking For? BME Dept Graduate Seminar, Worcester Polytechnic Institute, Worcester MA. Feb 22, 2012.
  12. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? Int. Conf. Biomed. & Health Informatics. Shenzhen, China, Jan 5, 2012.
  13. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? Int. Conf. Biomed. & Health Informatics. Pre-Conference Workshop. Hong Kong, China, Jan 3, 2012.
  14. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? IEEE Eng. Med. Biol. Conf, Buenos Aires, Argentina, Sept 2, 2010.
  15. Writing Scientific Papers, Korean Biomedical Engineering Society Meeting on Future Neurotechnologies for Neuron, Network and Brain, Seoul, May 14, 2010.
  16. Writing Scientific Papers, ISABEL 2009 (bioengineering conference), Bratislava, Slovakia, November 25, 2009.
  17. Writing Scientific Papers: Preparing your manuscript – what are the editors and reviewers looking for? IEEE Eng. Med. Biol. Conf, Minneapolis MN Sept 3, 2009.
Meet the Editors Presentations
  1. Meet the Editors. Shenzhen University, Oct 19, 2012.
  2. Meet the Editors. Chinese University of Hong Kong, Oct 18, 2012.
  3. Meet the Editors. BMEI’12-CISP’12, Chongqing, China, Oct 15, 2012.
  4. Meet the Editors. Guilin Biomedical Engineering Conference, China, October 13, 2012.
  5. Meet the Editors. IEEE TBME. Int. Conf. Biomed. & Health Informatics. Shenzhen, China, Jan 5, 2012.
  6. Meet the Editors. ISABEL 2009 (bioengineering conference), Bratislava, Slovakia, November 24, 2009.
  7. Meet the Editors. IEEE Eng. Med. Biol. Conf, Minneapolis MN Sept 3, 2009.
  8. Meet the Editors. IEEE Eng. Med. Biol. Conf, Vancouver, British Columbia, Aug 2008..
  9. Meet the Editors. IEEE Eng. Med. Biol. Conf, Lyon France, August 2007.
Invited Lectures and Presentations – Biomedical Engineering Overviews and Other
  1. The Future of our Students: USA Biomedical Engineering. Pontificia Universidad Católica del Perú, Lima, Peru, Nov 27, 2014.
  2. The Future of our Students: USA Biomedical Engineering. Favaloro University, Buenos Aires, Oct 27, 2014.
  3. Thoughts on the Future of Biomedical Engineering and Our Students, UCSD Bioengineering, February 11, 2014.
  4. The IEEE EMBS. Presentation to the Gainesville Chapter of the IEEE EMBS. Oct 9, 2013
  5. The Future of Biomedical Engineering, Valdosta State University, Georgia. Sept 5, 2013.
  6. Translational Biomedical Engineering: Experience at the University of Florida in Cardiovascular & Neural Applications and Overview of Department Research, BioFlorida Conference, Miami, Oct 8, 2012.
  7. Balancing BS, MS, PhD programs amidst new funding realities: Issues for BME programs, International BME Leaders and Department Heads Forum, IEEE EMBS Conf., Buenos Aires, Argentina, Aug 30, 2010.
  8. Developments in Biomedical Engineering. Talk to Gainesville Chapter of the IEEE EMBS. March 25, 2009.
  9. Starting a Bioengineering Department at the University of Illinois, invited talk, First International Conference on the Development of Biomedical Engineering in Vietnam, Ho Chi Minh City, July 27, 2005
  10. Future of Bioengineering at UIUC, informal presentation to the Dean of Engineering and key staff at the University of Texas at Dallas, Feb 20, 2004.
  11. Interdisciplinary Bioengineering Research and Programs at the University of Illinois. Invited talk, McMaster University, Workshop, Adaptive Systems Laboratory, Dec. 2, 2002.
  12. Bioengineering Opportunities for Electrical Engineers, graduate seminar to Konkuk University, Seoul, Korea, Feb 8, 2001.
  13. Undergraduate Electrical and Computer Engineering Education: Trends at the University of Illinois at Urbana-Champaign. ECE Department Seminar Seoul National University, Seoul, Korea, Sept, 1999.

 

     
Journal of Human on Chip Research Studies