Abdul-Hamid Emwas
Abdul-Hamid Emwas
Research scientist
  • :+966-2-8084313

King Abdullah University of Science and Technology
NMR Core lab room
Saudi Arabia

Education

2003 Ph.D in Physical Chemistry, University of New Brunswick, Fredericton, Canada
1998 M.Sc. in Biophysical Chemistry, University of Bergen, Bergen, Norway
1993 Bachelor of Science, B.Sc. (Chemistry), University of Bir-Zeit, Bir-Zeit, Palestine

 

Biography

Dr. Emwas received a Ph.D in Physical Chemistry from University of New Brunswick, Fredericton, Canada an d  Master of Science, M.Sc. in Biophysical Chemistry from University of Bergen, Bergen, Norway. He graduated earlier with B.Sc. (Chemistry) from University of Bir-Zeit, Bir-Zeit, Palestine
Currently Dr. Emwas working as research scientist at Advanced Nanofabrication Imaging and Characterization (NMR lab), King Abdullah University of Science and Technology, KSA. His research interest is in developing new NMR approaches for protein and DNA structural analysis.
Before that he worked at the Miami University, USA, CR UK Institute for Cancer Studies, UK and University of Waterloo, Waterloo, Canada

Currently Dr Emwas’ research focus on developing, optimizing and standardizing novel NMR metabolomics approaches that can be used as diagnostic and prognostic tool for human diseases.


Research Interest

His research interests are in the fields of Metabolomics and Biophysical Chemistry. Multidimensional ESR, MRI and NMR spectroscopy are Hispreferred instrumentation techniques.

  1. His research interest is in studying the structural properties of protein and other bio-macromolecules.
  2. Implementing NMR-metabolomic approach to monitor the metabolomics assessments of human health and nutrition.
  3. Integrate metabolomic along with proteomic, genomics, and transcriptomic techniques for a complete predictive picture of biological systems.
  4. Employing Solid state NMR and ESR to study transition metal of metalloenzyme and other bioinorganic systems.
  5. Investigation of the interaction of anticancer drugs with proteins, RNA and DNA is a primary interest.
  6. Using metabolomics approach to study the drug target on cancer cell lines, Breast cancer, 

Prostate cancer and Leukemia.

  1. Applying metabolomics on drug discovery and disease diagnosis.
  2. Optimizing and applying new solid state NMR techniques for structural elucidation of   to membrane proteins.

 

Professional Activities:

Research Scientist, July 2009 – present: NMR Core lab, King Abdullah University of Science and Technology, KSA

  1. Developing new NMR experiments for protein structural analysis.
  2. Users coordinator
  3. Preparing and supervising the preparation lab.

 

 

Publications

  1. Adamu, Sagir; Atiqullah, Muhammad; Malaibari, Zuhair O.; Al-Harthi, Mamdouh A.; Emwas, Abdul-Hamid M.; Ul-Hamid, Anwar. Metallocene- catalyzed ethylene-α-olefin isomeric copolymerization: A perspective from hydrodynamic boundary layer mass transfer and design of MAO anion. Journal of the Taiwan Institute of Chemical Engineers (2015),  Ahead of Print.
  2. Li, Sheng; Winters, Harvey; Jeong, Sanghyun; Emwas, Abdul-Hamid; Vigneswaran, Saravanamuthu; Amy, Gary L. Marine bacterial transparent exopolymer particles (TEP) and TEP precursors: Characterization and RO fouling potential. Desalination (2016), 379, 68-74.
  3. Alkordi, Mohamed H.; Haikal, Rana R.; Hassan, Youssef S.; Emwas, Abdul-Hamid; Belmabkhout, Youssef. Poly-functional porous-organic polymers to access functionality - CO2 sorption energetic relationships. Journal of Materials Chemistry A: Materials for Energy and Sustainability (2015), Ahead of Print.
  4. Li, S.; Winters, H.; Villacorte, L. O.; Ekowati, Y.; Emwas, Abdul-Hamid; Kennedy, M. D.; Amy, G. L. Compositional similarities and differences between transparent exopolymer particles (TEPs) from two marine bacteria and two marine algae: Significance to surface biofouling. Marine Chemistry (2015), 174, 131-140.
  5. Geng, Guoqing; Taylor, Rae; Bae, Sungchul; Hernandez-Cruz, Daniel; Kilcoyne, David A.; Emwas, Abdul-Hamid; Monteiro, Paulo J. M. Atomic and nano-scale characterization of a 50-year-old hydrated C3S paste. Cement and Concrete Research (2015), 77, 36-46.
  6. Batool, Farhat; Parveen, Shehla; Emwas, Abdul-Hamid; Sioud, Salim; Gao, Xin; Munawar, Munawar A.; Chotana, Ghayoor A. Synthesis of Fluoroalkoxy Substituted Arylboronic Esters by Iridium-Catalyzed Aromatic C-H Borylation. Organic Letters (2015), 17(17), 4256-4259.
  7. Liu, Zhaohui; Dong, Xinglong; Zhu, Yihan; Emwas, Abdul-Hamid; Zhang, Daliang; Tian, Qiwei; Han, Yu. Investigating the Influence of Mesoporosity in Zeolite Beta on Its Catalytic Performance for the Conversion of Methanol to Hydrocarbons. ACS Catalysis (2015), 5(10), 5837-5845.
  8. Alezi, Dalal; Belmabkhout, Youssef; Suyetin, Mikhail; Bhatt, Prashant M.; Weselinski, Lukasz J.; Solovyeva, Vera; Adil, Karim; Spanopoulos, Ioannis; Trikalitis, Pantelis N.; Emwas, Abdul-Hamid; et al. Journal of the American Chemical Society (2015), 137(41), 13308-13318. 
  9. Gonzalez-Gil, Graciela; Thomas, Ludivine; Emwas, Abdul-Hamid; Lens, Piet N. L.; Saikaly, Pascal E. NMR and MALDI-TOF MS based characterization of exopolysaccharides in anaerobic microbial aggregates from full-scale reactors. Scientific Reports (2015), 5, 14316.
  10. FA Mahboub, FA Khorshid, AHM Emwas. The Cytotoxic Effect of Small and Large Molecules of PMF Fraction Extracted from Camel Urine on Cancer Cells. British Journal of Medicine and Medical Research (2015) 6 (4), 384.
  11. 114.Emwas, Abdul-Hamid; Luchinat, Claudio; Turano, Paola; Tenori, Leonardo; Roy, Raja; Salek, Reza M.; Ryan, Danielle; Merzaban, Jasmeen S.; Kaddurah-Daouk, Rima; Zeri, Ana Carolina; et al. Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review. Metabolomics (2015), 11(4), 872-894.
  12. Al-Bloushi, Mohammed; Davaasuren, Bambar; Emwas, Abdul-Hamid; Rothenberger, Alexander. Synthesis and Characterization of the Quaternary Thio-aluminogermanates A(AlS2)(GeS2) (A = Na, K). Zeitschrift fuer Anorganische und Allgemeine Chemie (2015), 641(7), 1352-1356..
  13. Atiqullah, Muhammad; Al-Harthi, Mamdouh A.; Anantawaraskul, Siripon; Emwas, Abdul-Hamid M. Ethylene homo- and copolymerization chain-transfers: A perspective from supported (nBuCp)2ZrCl2 catalyst active centre distribution. Journal of Chemical Sciences (2015), 127(4), 717-728.
  14. Chisca, S.; Duong, P. H. H.; Emwas, A.-H.; Sougrat, R.; Nunes, S. P. Crosslinked copolyazoles with a zwitterionic structure for organic solvent resistant membranes . Polymer Chemistry (2015), 6(4), 543-554.
  15. Zubair, Mukarram; Jose, Jobin; Emwas, Abdul-Hamid; Al-Harthi, Mamdouh A. Effect of modified graphene and microwave irradiation on the mechanical and thermal properties of poly(styrene-co-methyl methacrylate)/graphene nanocomposites. Surface and Interface Analysis (2014), 46(9), 630-639.
  16. K Celik, MD Jackson, M Mancio, C Meral, A-H Emwas, PK Mehta, PJM Monteiro. High-volume natural volcanic pozzolan and limestone powder as partial replacements for portland cement in self-compacting and sustainable concrete. Cement and Concrete Composites. (2014) 45, 136-147.
  17. Muhammad Tariq Khan, Markus Busch, Veronica Garcia Molina, Abdul-Hamid Emwas, Cyril Aubry, Jean-Philippe Croue. How different is the composition of the fouling layer of wastewater reuse and seawater desalination RO membranes? Water Research. (2014) 59, 271-282.
  18. Ahmed Nageeb, Azza Al-Tawashi, Abdul-Hamid Mohammad Emwas, Zeyad Abdel-Halim Al-Talla, Nahla Al-Rifai. Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts. Current Bioactive Compounds. (2013) 9, 324-332.
  19. M. Bouhrara, Chanakya Ranga, Aziz Fihri, R. R. Shaikh, Pradip Sarawade, Abdul-Hamid Emwas, Mohamed Nejib Hedhili and Vivek Polshettiwar. Nitridated Fibrous Silica (KCC-1) as a Sustainable Solid Base Nanocatalyst. ACS Sustainable Chemistry & Engineering. (2013) 1, 1192-1199.
  20. Muhammad Atiqullah, Siripon Anantawaraskul, Abdul-Hamid M Emwas, Mamdouh A Al-Harthi, Ikram Hussain, Anwar Ul-Hamid, Anwar Hossaen. Effects of Supported (n BuCp) 2ZrCl2 Catalyst Active-Center Distribution on Ethylene–1-Hexene Copolymer Backbone Heterogeneity and Thermal Behaviors. Industrial & Engineering Chemistry Research(2013) 52(27), 9359-9373.
  21. Muhammad Atiqullah, Siripon Anantawaraskul, Abdul‐Hamid M Emwas, Mamdouh A Al‐Harthi, Ikram Hussain, Anwar Ul‐Hamid, Anwar Hossaen. Silica‐supported (nBuCp) 2ZrCl2: effect of catalyst active center distribution on ethylene–1‐hexene copolymerization. (2013) online, DIO 10.1002/pi.4587.
  22. M. D. Jackson, J. Moon, E. Gotti, R. Taylor, S. R. Chae,  M. Kunz, Abdul-Hamid Emwas, C. Meral , P. Guttmann, P. Levitz, H.-R. Wenk,  P. J. M. Monteiro. Material and elastic properties of Al-tobermorite in ancient Roman seawater concrete. Journal of the American Ceramic Society. (2013) 96, 2598-2606.
  23. M Shahzad Kamal,  Bijal Kottukkal Bahuleyan, Omer Bin Sohail, Abdul-Hamid M. Emwas, John E. Bercaw  and Mamdouh A. Al-Harthi. Crystallization analysis fractionation of poly(ethylene-co-styrene) produced by metallocene catalysts. Polymer Bulletin. (2013) 70, 2645-2656. 
  24. Mohamed Bouhrara, Chanakya Ranga, Aziz Fihri, Rafik R Shaikh, Pradip Sarawade, Abdul-Hamid Emwas, Mohamed N Hedhili, Vivek Polshettiwar. Nitridated Fibrous Silica (KCC-1) as a Sustainable Solid Base Nanocatalyst. ACS Sustainable Chemistry & Engineering. (2013) 1 1192-1199.
  25. Abdul-Hamid M. Emwas, Reza M Salek, Julian L. Griffin and Jasmeen Merzaban. NMR-based metabolomics in human disease diagnosis: applications, limitations, and recommendations. Metabolomics. (2013) 5, 1048-1072.
  26. Misjudeen Raji; Maan Amad; and Abdul-Hamid Emwas. Dehydrodimerization of Pterostilbene during  Electrospray Ionization Mass Spectrometry. Rapid Communications in Mass Spectrometry. (2013) 27, 1260–1266.
  27. Abdul-Hamid M. Emwas, Zeyad A. Al-Talla, Xianrong Guo, Suliman Al-Ghamd,and Harbi T. Al-Masri. Utilizing NMR and EPR spectroscopy to probe the role of copper in prion diseases.  Magnetic Resonance in Chemistry.  (2013), 51(5), 255-268.
  28. Shyamal K. Das, Shaomao Xu, Abdul-Hamid Emwas, Ying Ying Lu,a Samanvaya Srivastava and Lynden A. Archer. High energy lithium–oxygen batteries – transport barriers and thermodynamics. Energy & Environmental Science. (2012) 5, 8927-8931
  29. Umesh Patil, Aziz Fihri, Abdul-Hamid Emwas and Vivek Polshettiwar. Silicon Oxynitrides of KCC-1, SBA-15 and MCM-41: Unprecedented Materials for CO2 Capture with Excellent Stability and Regenerability. RSC Chemical Science. (2012) 3, 2224-2229
  30. M. Atiqullah1, M. S. Winston, J. E. Bercaw, I. Hussain, A. Fazal, M. Al-Harthi, Abdul-Hamid Emwas, M. J. Khan, A. Hossaen. Effects of a vanadium post-metallocene catalyst-induced polymer backbone inhomogeneity on UV oxidative degradation of the resulting polyethylene film. Polymer Degradation and Stability. (2012) 97, 1164-1177
  31. Harbi Al-Masri, Abdul-Hamid M. Emwas, Zeyad Al-Talla,and Mohamed. AlKordi  Synthesis and characterization of new N-(diphenylphosphino)naphthylamine chalcogenides: X-ray structures of C10H7-1-HNP(Se)Ph2 and Ph2P(S)OP(S)Ph. Phosphorus, Sulfur, and Silicon and the Related Elements. (2012) 187,1082–1090.
  32. Bijal Kottukkal Bahuleyan, S. K. De, P. U. Sarath, Sarfaraz Ahmed Furquan, J Masihullah, Abdul Hamid Emwas, Mamdouh A. Al-Harthi. Effect of aluminium nitride on the properties of polyethylene obtained by In situ polymerization using Ni(II) diimine complex. Macromolecular Research. (2012) 20, 772-775.
  33. Zeyad A. Al-Talla, Luke Tolley, Mohammed F. Zaater, Sabah H. Akrawi and Abdul-Hamid M. Emwas. Bioequivalence Assessment of Two Formulations of Ibuprofen. Drug Design, Development and Therapy (2011) 5, 427-433.
  34. Daniel Mayo, Andy Zhou, Indra Sahu, Robert McCarrick, Parker Walton, Adam Ring, Kaylee Troxel, Aaron Coey, Jaclyn Hawn, Abdul-Hamid Emwas, and Gary A. Lorigan. Probing the structure of membrane proteins with electron spin echo envelope modulation spectroscopy. Protein Science (2011) 20, 1100-1104.  
  35. Daniel J. Mayo, Andy Zhou, Indra Dev Sahu, Robert M. McCarrick, Parker J. Walton, Adam C. Ring, Kaylee R. Troxel, Aaron T. Coey, Jaclyn M. Hawn, Abdul-Hamid Emwas and Gary A. Lorigan. Utilizing Electron Spin Echo Envelope Modulation (ESEEM) Spectroscopy to Probe the Structure of Membrane Proteins. Biophysical Journal (2011) 100, 144a
  36. Zeyad A. Al-Talla, Sabah H. Akrawi  and Abdul-Hamid Emwas. Solid State NMR and Bioequivalence Comparison of the Pharmacokinetic Parameters of Two Formulations of Clindamycin. International Journal of Clinical Pharmacology and Therapeutics (2011) 49(7) 469-476.
  37. Kirchheim, Ana Paula, Dal Molin, Denise, Provis, John, Emwas, Abdul-Hamid, Fischer, Peter and Monteiro, Paulo. Real-time high-resolution X-ray imaging and nuclear  magnetic resonance study of the hydration of pure and Na-doped C3A in the presence of sulfates. Inorganic Chemistry (2011) 50, 1203-1212.
  38. Shidong Chu, Sergey Maltsev, Emwas, A-H, Gary A. Lorigan. Solid-state NMR Paramagnetic Relaxation Enhancement Immersion Depth Studies in Phospholipid Bilayers. J. Magn. Reson. (2010) 207, 89-94.
  39. Joanna Oommen, Muhammad Hussain, Abdul-Hamid M. Emwas, Praveen Agarwal, and Lynden A. Archer. Nuclear Magnetic Resonance Study of Nanoscale Ionic Materials. Electrochem. Solid-State Lett. (2010) 13, 87-88. 
  40. Christian Ludwig, Ildefonso Marin-Montesinos§, Martin G Saunders, Abdul-Hamid Emwas, Zoe Pikramenou, Stephen P Hammond and Ulrich L Günther. Application of ex situ Dynamic Nuclear Polarization in Studying Small Molecules. Physical Chemistry Chemical Physic. 2010, 12, 5868 – 5871.
  41. Kamal H. Mroué, Abdul-Hamid M. Emwas, and William P. Power, "Solid-state 27Al Magnetic Resonance Investigation of Three Aluminum-Centred Dyes," Canadian Journal of Chemistry. (2010) 88, 111-123
  42. Linenberger, KJ; Emwas, AH; Peat, I, et al. Using NMR to determine the structure of a peptide: An inquiry approach for an upper level undergraduate laboratory. American Chemical Society. (2009) 237, 136-CHED
  43. A. Latif Abuhijleh Hijazi Abu Ali and Abdul-Hamid Emwas. Synthesis, spectral and structural characterization of dinuclear rhodium (II) complexes of the anticonvulsant drug valproate with theophylline and caffeine. Journal of Organometallic Chemistry  (2009) 694, 3590–3596
  44. Emwas, A.-H.; Saunders, M.; Ludwig, C.; Guenther, U. L.   Determinants for optimal enhancement in ex site DNP experiments.  Applied Magnetic Resonance  (2008)  34,  483-494
  45. S. Tiziania, Abdul H. Emwas, C. Ludwig,M. R. Viant and U. L. Günther. Optimised Metabolite Extraction from Blood Serum for 1H Nuclear Magnetic Resonance Spectroscopy. Analytical Biochemistry (2008) 377,  16-23.
  46. Sahloul, N.; Emwas A. H. Pwoer W. and Penlidis A. Ethyl Acrylate-Hydroxyethyl Acrylate and Hydroxyethyl Acrylate-Methacrylic Acid: Reactivity Ratio Estimation from Cross-linked Polymer Using High Resolution Magic Angle Spinning Spectrometry. J. MacromolecularScience. (2005) 42, 1369-1385.
  47. Andreas Decken, S. M. Mattar and A. Emwas. 1,4,11,12-Tetra¬hydro-9,10-anthraquinon. Acta Crystallographica E. (2005) 61, 641.
  48. Saba. M. Mattar, Abdul H. Emwas and Larry A. Calhoun. Spectroscopic Studies of the Intermediates in the Conversion of 1,4,11,12-Tetrahydro-9,10-anthraquinone to 9,10-Anthraquinone by Reaction with Oxygen under Basic Conditions. J. Phys. Chem. A. (2004) 108, 11545-11553.
  49. Abdul-Hamid Muhammad Emwas. Electron and Nuclear Magnetic Resonance Studies of Some Biologically Relevant Model Para-Semiquinones. PhD thesis, University of New Brunswick, Canada 2003.
  50. Mattar, S. M. and Emwas, A. H. A Novel Doubly Stacked Dielectric Resonator Housed in an Intact TE 102 Cavity. Chem. Phys. Let. (2003) 368, 724-731.
  51. Mattar, S. M.; Emwas, A. H. and Stephens, A. Accurate computations of the methyl isotropic hyperfine coupling constants in 2-methyl-1,4-benzosemiquinone radical intermediate. Chem. Phys. Lett. (2002) 363, 152-160.
  52. Mattar, S. M.; Stephens, A. and Emwas, A. H. Generation and Spectroscopic Characterization of the 2,3,5,6-Tetramethoxy-1,4-Benzosemiquinone Reactive Intermediate. Chem. Phys. Let. (2002) 352, 39-47.
  53. Abdul-Hamid Muhammad Emwas. NMR Studies of Copper Complexation of Adenosine monophosphate Nucleotides and anti Viral Nucleotide Analogues PMEA. Master thesis. University of Bergen Norway 1998.
  54. Sabri, K. S. and Emwas, A. H. The Relation between Scholl Laboratory Experiments of Palestinian Students in Introductory University Science Courses. Research in Post-Compulsory, Vol. 4, No. 1, 1999.
  55. Blindaauer, C.; Emwas, A.; Hana D., A.; Sletten, E. and Sigel, H., Complex Formation of the Antiviral 9-[2-(Phosphonomethoxy) ethyl] adenine (PMEA) and of its N1, N3 and N7 Deaza Derivatives. Chem. Eur. J. (1997) 9, 1526-1536.

 

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