Professional Activities

Present and Previous Academic Rank and Positions

• Professor of Immunology, Mayo Medical School
• Emeritus Staff, Departments of Neurology and Immunology, Mayo Clinic, Mayo Medical Center
• Clinician-Investigator, Mayo Medical School- through 12/31/14
• Director, Center for Multiple Sclerosis and Central Nervous System Demyelinating Diseases Research and Therapeutics (CMSDD) - through 12/31/14
• Chair, CMSDD Administrative Committee - through 12/31/14
• Mildred A. and Henry Uihlein Professor of Medical Research- through 12/31/14

Honors/Awards

• 9/75: Alpha Omega Alpha, Medical Honor Society
• 2/76: Bernard M. Baruch Award - for outstanding experimental research as a medical student in rehabilitation medicine, paper entitled "Neurotransmitters in Spinal Cord Injury" sponsored by the American Congress of Rehabilitation Medicine
• 6/77: Northwestern University Medical School Service Award - for the establishment of "Erie Clinic", Northwestern University Service Clinic for underprivileged Latin Americans
• 6/81-6/83: Mayo Foundation Scholar, Univ. of California at San Diego
• 6/82: Weil Award - Best paper in experimental neuropathology presented at the annual meeting of the American Association of Neuropathology, "Ultrastructural Localization of Viral Antigens in the CNS of Mice Persistently Infected with Lymphocytic Choriomeningitis"
• 6/83-6/86: Rappaport Scholar of the Mayo Medical School to study virus-induced demyelination
• 9/83-9/88: Teacher Investigator Award (NINCDS, NS 00849) - "Mechanisms of Viral-induced Demyelination"
• 10/86-10/89: John G. Searle Fellowship, Searle Scholars Program of the Chicago Community Trust
• 11/86-6/90: Member, Neurological Disorders Program Project Review A Committee (NIH)
• 9/87: Member of American Neurological Association
• 7/92: Clinician Investigator, Mayo Medical School
• 11/93-11/97: Member, Training Grant and Career Development Review Committee, National Institute of Neurological Disorders and Stroke (NIH)
• 11/00-Present: Mildred A. and Henry Uihlein Professor of Medical Research
• 10/04-10/07 Councilor of the American Neurologic Association
• 04/07 – Present: Global Directory of Who’s Who
• 05/07: Dean’s Recognition Award, Mayo Graduate School
• 04/08: Frontiers in Neuroscience Award, American Academy of Neurology
• 01/09: Distinguished Investigator Award, Mayo Clinic
• 2009: Elected to Best Doctors in America
• 2011: Elected to Edition of Who’s Who in America

Previous Professional Positions and Appointments

• 6/81-6/83: Mayo Foundation Scholar
• 7/83-Present: Consultant, Department of Neurology, Mayo Clinic, Rochester, MN
• 12/83-6/87: Assistant Professor of Neurology, Mayo Medical School, Rochester, MN
• 1/85-Present: Consultant, Department of Immunology, Mayo Clinic and Research Foundation, Rochester, MN
• 7/87-6/90: Associate Professor of Neurology, Mayo Medical School, Rochester, MN
• 7/90-Present: Professor of Neurology, Mayo Medical School, Rochester, MN
• 7/92-Present: Clinician-Investigator, Department of Neurology, Mayo Medical School, Rochester, MN
• 11/94-12/06: Director, M.D./Ph.D. MSTP Program, Mayo Medical School
• 7/97-Present: Professor of Immunology, Mayo Medical School, Rochester, MN
• 11/00-Present: Mildred A. and Henry Uihlein Professor of Medical Research
• 7/96-12/02: Chair, Division of Neuroimmunology
• 1/03-7/04: Chair, Division of Demyelinating Disorders

Professional Memberships

Societies

• Alpha Omega Alpha (Medical Honor Society)
• American Academy of Neurology     
• Sigma Xi (Scientific Honorary Society)
• American Association of Neuropathologists 
• American Society for Neurologic Investigation
• Mayo Alumni Association
• American Association for the Advancement of Science
• Minnesota Society for Neurological Sciences
• American Society of Virologists
• Central Society for Neurologic Research
• American Neurologic Association
• Society for Neuroscience
• European Charcot Foundation for Multiple Sclerosis Research
• International Society for Neurovirologists
• National Hispanic Medical Association

Study Section

• Member, Neurological Disorders Program Project Review A Committee (NSP-A) of the National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) (11/86-6/90).
• Member, Training Grant and Career Development Review Committee of the National Institute of Neurological Disorders and Stroke (11/93-6/97)
• Member, National Multiple Sclerosis Society - Scientific Review Committee (5/99 - 5/03)
• Chair, National Multiple Sclerosis Society - Scientific Review Committee (11/00 - 11/04)
• Member, Review Committee Interdisciplinary Individual Postdoctoral Fellows for Training in Neurodegeneration Research (F32) RFA AG-07-004 ZDA1-MXH-H (09) (03/07 –  present)
•  Member, Review Committee, ZNS1 SRB-M National Institute of Neurological Disorders and Stroke- Loan Repayment Program (03/07- present)
• Member, Fast Forward Scientific and Business Advisory Committee, Fast Forward LLC (a non-profit company wholly owned by the NMSS), (09/07 – present)
• Member, Special Emphasis Panel, Diversity Predoctoral Fellowship Applications ZRG1 IMM-L 29 (01/08 – present)
• Member, Advisory Board for Peer Review, Biomedicine 2012, Fondazione Cariplo, (10/12-present)

Educational Activities

Curriculum/Course Development and Coordination

• Preceptor: Student Interim Program, Mayo School of Health Related Sciences (1987-Present)
• Staff Advisor: Neurology residents (Claudia Lucchinetti, Dan Wynn, Helmi Lutsep, Andrew Reeves, Sam Hunter, William Hogancamp)
• Member: Post Graduate Education Committee (Neurology Department) (1985-1990)
• Preceptor: Third Year Mayo Medical students who elect a 6-month rotation in neurovirology laboratory (1987-present)
• Member: Graduate School in Immunology and Molecular Neurosciences (1987- present)
• Lecturer: Mayo Medical School on Demyelinating Diseases (1987)
• Course Director: "Viral Pathogenesis" for the Mayo Graduate School (1990)
• Member: Resident Selection Committee (Neurology Department) (1989-1994)
• Ph.D. Thesis Advisor: Dave Miller, Department of Immunology (1991-1994)
• Ph.D. Examining Committee: Dan Kaufman, Department of Immunology (1992-1997)
• Ph.D. Examining Committee: Eric Rohren, Department of Immunology (1992-1994)
• Course Director: “Infection and Immunity" for Mayo Graduate School (1992)
• Member: Mayo Group Practice Neurology Education Coordinating Committee (1993-present)
• Preceptor: Summer Undergraduate Research Program (Depts. of Immunology and Molecular Neurosciences) (1988-present)
• Director: M.D./Ph.D. Program, Mayo Medical School (1994-present)
• Course Director: "Immunopathology" for Mayo Graduate School (1995)
• Ph.D. Examining Committee: Bryce Binstadt, Department of Immunology (1995-1998)
• Ph.D. Thesis Advisor: Paul Murray, Department of Immunology (1995-1999)
• Ph.D. Thesis Advisor: Dorian McGavern, Molecular Neuroscience Program (1996-2000)
• Ph.D. Examining Committee: Paul Tiseo, Molecular Neuroscience Program (1996-1998)
• Ph.D. Thesis Advisor: M. Mateo Paz Soldan, Molecular Neuroscience Program (1998-2002)
• Course Director: "Tutorial in Immunopathology" (1997)
• Ph.D. Examining Committee: Ryan A. Wilcox, Department of Immunology (1999-2002)
• Course Director: "Infection and Immunity", Department of Immunology, Mayo Graduate School Tutorial (1999)
• Ph.D. Thesis Committee: Aaron J. Johnson, Department of Immunology (1996-2001)
• Ph.D. Examining Committee: Yanice Mendez-Fernandez, Department of Immunology (2000-2004)
• Mayo graduate faculty member, Virology and Gene Therapy (2003-present)
• Ph.D. Thesis Committee: Yazmin Morales, Department of Neurology (2003-present)
• Eric Buenz – Ph.D. Thesis Advisor – Department of Cellular and Molecular Neuroscience (2004 to 2008)
• Aaron Nelson – M.D. Ph.D. Thesis Advisor – Department of Cellular and Molecular Neurosciences (2003 to 2004)
• Ph.D. Thesis Committee: Alexander Vandell, Molecular Neuroscience Program (2006 to 2009)
• Ph.D. Thesis Advisor: Aleksandar Denic, Molecular Neuroscience Program (2005 to 2009)
• M.S. Thesis Committee: Reem F. Bunyan, M.D. (2009 to 2011)
•  Ph.D. Thesis Advisor: Meghan Painter, Molecular Neuroscience Program (2010 to Present)

Mentorship - Graduate Students/Postdoctoral Fellows/Medical Students/Visiting Scientists

• Jawaid Quddus, Ph.D. - Postdoctoral Fellow (1983 - 1985)
• Claudia Lucchinetti - Northwestern University (Summer Immunology Student 1984, 1985, and 1986)
• Christine Shover - Gustavus Adolphus College, St. Peter, MN (Summer Interim Student -           1985)
• Mollie Ross, Muskingum College, New Concord, OH (Summer Interim Student - 1986)
• Jennifer J. Schmidt - Lawrence University, Appleton, WI (Summer Interim Student - 1986)
• Amy Patick, Ph.D. - Postdoctoral Fellow (1986 - 1990)
• Mark Lindsley, Ph.D. - Postdoctoral Fellow (1986 - 1990)
• Helmi Lutsep, M.D. - Mayo Medical School Student (1987)
• Dan Wynn, M.D. - Neurology resident (1987 - 1988)      
• George Dempsey, M.D. - Mayo Medical School Student (1988)
• Naraporn Prayoonwiwat, M.D. - Postdoctoral Fellow sponsored by the Thai Medical Council (1988 - 1992)         
• Julie Nyhus - Grinnell College, Grinnell, IA (Summer Research Program, Mayo Graduate School  - 1989)
• Alec Dunkel - Lawrence University, Appleton, WI (Summer Immunology Student, Mayo Graduate School, 1990 and 1991)
• Dave Miller - Graduate student (M.D./Ph.D), Mayo Medical School (1990 - 1994)
• Kim Jacobsen, Ph.D. - Postdoctoral Fellow (1991 - 1993)
• Kirsten Vadheim, Ph.D. - Postdoctoral Fellow (1991 - 1993)
• Ayse Altintas, M.D. - Research Trainee, Ege University, Izmir, Turkey (1991 - 1992)
• Tahnee Hartman - Hope College, Holland, MI  (Summer Immunology Student, 1991)
• Aksel Siva, M.D. - Visiting Scientist, Istanbul University, Istanbul, Turkey (1991 - 1992)
• Xiaoqi Lin, M.D., Ph.D. - Postdoctoral Fellow, Chinese Academy of Medical Sciences, Beijing, China (1991 - 1998)
• Charles Howe - University of Wisconsin, Eau Claire (Summer Undergraduate Research Fellow in Molecular Neuroscience - 1992)
• Andrew Lange - University of Wisconsin, Stevens Point, WI (Summer Undergraduate Research Fellow in Immunology - 1992)
• Brian Iuliano - Mayo Medical School Student (1992)
• Martin Holtman - Extramural Visiting Medical School Clerkship, University of  Witten/Herdecke, Germany (1992)
• Baziel van Engelen, M.D., Ph.D. - Postdoctoral Fellow, University Hospital Nijmegen, The        Netherlands (1993 - 1994)
• Kunihiko Asakura, M.D. - Postdoctoral Fellow, Nagoya University School of Medicine, Nagoya, Japan (1993 - 1999)
• Christopher W. McKinney - Massachusetts Institute of Technology, Cambridge, MA (Summer Interim Student - 1993)
• Pamela Snyder - Mount Holyoke College, South Hadley, MA (Summer Undergraduate Research Fellow in Molecular Neurosciences, Baxter Scholar - 1993)
• Deborah Alpert - Binghamton University, Binghamton, NY (Summer Undergraduate Research Fellow in Immunology, Abbott Fellow - 1993)
• Ivona Brasnjevic – M.D./Ph.D. Student, Mayo Medical School (October-December, 2003)
• Teodora Staeva - Macalster College, St. Paul, MN (Undergraduate Research Internship Program - 1994, Winter and Summer)
• Samuel Hunter - Mayo Neurology Resident, Clinician Investigator Program (1993 - 1997)
• William E. Hogancamp - Mayo Neurology Resident (Research Elective, 1994, Neuroimmunology Fellow, 1995)
• Michelle Carlo, University of Puerto Rico, Rio Piedras, Puerto Rico (Minority Medical Student Summer Research Program, 1994)
• Amy Weinmann, University of Minnesota at Morris, Morris, MN (Summer Undergraduate          Research Fellow in Immunology - 1994)
• Claudia Lucchinetti - Neuroimmunology Clinical Fellow (1994 - 1995), Mayo Neurology Resident
• Michael Thompson - M.D./Ph.D. Student, Mayo Medical School (Summer 1994)
• Cynthia Rivera-Quiñones, Ph.D. - Postdoctoral Fellow, Ponce School of Medicine, Puerto          Rico (1994 - 1997)
• Moses K. Njenga, Ph.D. - Postdoctoral Fellow, Pennsylvania State University (1994 - 1999)
• Nancy D. Borson, Ph.D. - Postdoctoral Fellow, University of Minnesota (1994 - 1998)
• Paul Murray - Graduate Student, Immunology Department (M.D/Ph.D) (1995 - 2000)
• Rafael L. Ufret-Vincenty, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.  (Minority Medical Student Summer Research Program, 1995)
• Jennifer Carnell - Macalester College, St. Paul, MN (Summer Undergraduate Research Fellow in Immunology - 1995)
• Loc T. Nguyen - Graduate student (M.D./Ph.D.), Mayo Medical School (Summer - 1995)
• Kristen Drescher, Ph.D. - Postdoctoral Fellow, Johns Hopkins University, Baltimore, MD           (1995 -1999)
• Dorian McGavern - Graduate student, Molecular Neuroscience Program (1996 - 2000).
• Maya Schreiber - Smith College (Summer Undergraduate Research Fellow in Immunology         - 1996)
• Daren Ure, Ph.D. - Postdoctoral Fellow, University of Alberta, Edmonton, Alberta, Canada (1997 - 2002)
• Yanice Mendez - University of Puerto Rico, Rio Piedras, Puerto Rico.  (Minority Medical Student Summer Research Program in Immunology, 1997)
• Arthur Warrington, Ph.D. - Research Associate, University of Connecticut, Farmington, CT (1997 - 2004)
• Allan Bieber, Ph.D. - Special Project Associate, Purdue University, West Lafayette, IN (1997 - 2002)
• M. Mateo Paz Soldan – Graduate Student, Molecular Neuroscience Program (1998 - 2002).
• Dyana T. Saenz – Texas A&M University, College Station, TX (Summer Undergraduate          Research Fellow in Immunology – 1998)
• Joy Kong – Special Project Associate, San Francisco State University, San Francisco, CA (1998)
• Isobel A. Scarisbrick - University of California, Irvine.  Research Associate (1998 – 2002).
• Dean Wingerchuk, M.D. – Neuroimmunology Fellow, University of Saskatoon, Saskatoon, Canada (1999 - 2000)
• Sith Sathornsumetee – Mahidol University, Bangkok, Thailand, Research Trainee (1998 – 2000)
• Cody Koch – Drake University (Summer Undergraduate Research Fellow in Immunology 1999)
• Won Yong Lee - Predoctoral Neuroscience Student (1999)
• Mark Keegan, M.D. – Neuroimmunology Fellow, University of Saskatoon, Saskatoon, Canada (1999-2001)
• Caroline Cole - Immunology Program, Graduate Student - Colorado State University, Fort Collins, CO (1999)
• Ryan Wilcox - Immunology Program (M.D./Ph.D.), Thesis Advisory Committee (2000 - 2002)
• Jamie L. Wood - North Carolina State University (Summer Undergraduate Research Fellow in Immunology - 2000)
• Don N. Chang - University of Southern California (Summer Undergraduate Research Fellow in Molecular Neurosciences - 2000)
• Meenakshi Khare – Postdoctoral Fellow, King George Medical College, Lucknow, India (06/00-09/06)
• Zhou Bin, Ph.D. - Postdoctoral Fellow, University of Minnesota, Minneapolis, MN (2000 - 2001)
• Erin Schenk - Gustavus Adolphus College (Summer Undergraduate Research Fellow in Immunology - 2001)
• Charles L. Howe, Ph.D. - Postdoctoral Fellow, University of California at San Francisco/Stanford (2001 - 2004)
•  Ashutosh Mangalam – Postdoctoral Fellow, School of Biotechnology, Devi Ahilya University, Indore (07/01-present)
• Aaron Johnson, Ph.D. - Postdoctoral Fellow, University of Minnesota at Duluth, MN (2001 -2002)
• Istvan Pirko, M.D. – Neuroimmunology Fellow, University of Ohio (2001 - 2003)
• William T. Mayr – Neurology Resident (Epidemiology of Multiple Sclerosis) (2000 - 2003)
• Sean Pittock – Neurology Resident (Epidemiology of Multiple Sclerosis) (2000 - 2003)
• Sean Pittock – MS Fellow (2003 - 2005)
• Lyndsey Benson – Summer Undergraduate Research Fellow in Molecular Neuroscience, Brown University, Providence, RI  (2003)
• William Gardella – Summer Undergraduate Research Fellow in Immunology, Vanderbilt University, Nashville, TN (2003)
• George Christophi – Summer Undergraduate Research Fellow in Molecular Neuroscience, Richard Stockton University, NJ (2003)
• Odey Ukpo – Minority Medical Student Summer Program, Loyola Stritch School of Medicine, IL  (2003)
• Araya Puwanant, M.D. – Research Trainee, Siriraj Hospital, Bangkok, Thailand (2004)
• Eric Buenz- Ph.D. Thesis Advisor- Department of Cellular and Moleculare Neurosciences (3/04 to 08/06)
• Aaron Nelson – M.D.Ph.D. Thesis Advisor Department of Cellular and Molecular Neurosciences (3/03 – 12/04)
• Dale Edberg, Ph.D. – Postdoctoral Fellow, Washington State University (8/04-9/09)
• Chandra Deb, Ph.D. – Postdoctoral Fellow, North Bengal University, India (5/05-4/09)
• Aleksandar Denic, M.D. – Postdoctoral Fellow, Medical University in Belgrade, Serbia, (05/05 –07/07)
• Priyanka Sabharwal – Ph.D. Thesis Advisor – Department of Cellular and Molecular Neuroscience (10/03-05/05)
• Brent Wright, Ph.D., Postdoctoral Fellow, University of South Dakota (5/06-Present)
• Jaimie Adelson – Summer Undergraduate Research Fellow in Immunology, Grinnell College, IA (2006)
• Rachel Bergstrom -– M.D/Ph.D. Student, Mayo Clinic College of Medicine, (Summer 2006)
• Zheyan Chen – M.D/Ph.D. Student, Mayo Clinic College of Medicine, (Summer 2006)
• Natalia Klosak – Summer Undergraduate Research Fellow in Immunology, University of North Florida (2006).
• Doris Nguyen – M.D/Ph.D. Student, Mayo Clinic College of Medicine, (Summer 2006)
• Viktorija Velanac, Ph.D. Student, Max Planck Institute of Experimental Medicine, Goettingen, Germany, (Fall 2006).
• Aleksandar Denic, M.D., Thesis Advisor, Department of Cellular and Molecular Neuroscience (07/07 – 04/11).
• Kanitta Suwansrinon, M.D., University of Bangkok, Postdoctoral Fellow (10/07 to 06/10)
• Filiz Kerdige – M.D. Student, Hacettepe University, Ankara, Turkey (Summer 2008)
• Ramakrishna Edukulla, Ph.D., Hannover Medical School, Germany, Postdoctoral Fellow (4/09 to 3/11)
• Jens Watzlawik, Ph.D., Georg-August University (Goettingen, Germany), Postdoctoral Fellow (4/07 to present)
• Xiaohua Xu, Ph.D., Chinese Academy of Sciences, Postdoctoral Fellow (4/09 to 12/14)
• Emily Esch, Summer Undergraduate Research Fellow (2009)
• Jessica Floyd, M.D., Neurology Resident Mayo Jacksonville (04/2010)
• Beth Bw’Omete, Summer Undergraduate Research Fellow (2010)
• Spencer Gladis, Hayfield High School science mentorship student (6/10 to 8/11)
• Bharath Wootla, Ph.D., INSERM (Paris), Postdoctoral Fellow (09/10 to present)
• Emily Esch Ramírez, Ph.D. Student (08/10 to 03/12)
• Meghan Painter, Ph.D. Student, (09/10 to present)
• Estefania Mondragón, Ph.D. Student (08/10 to 12/10)
• Benjamin Wu, Brown University, Research Trainee (03/11 to 08/11)
• Danielle Renner, Ph.D. Student (02/11 to 5/11)
• Aleksandar Denic, M.D., Ph.D., University of Belgrade and Mayo Graduate School, Postdoctoral Fellow, (04/11 to 03/14)
• Makoto Eriguchi, M.D., Ph.D. Saga University Hospital, Saga City, Japan, Research Trainee (06/11 to present)
• Mehmet Yaman, M.D., Afyon Kocatepe University, Afyon, Turkey, Research Trainee (06/11 to 08/11)
• William Matchett,  Augsburg College, Summer Student funded by the Minnesota Chapter of the NMSS (2011)
• M. Mateo Paz Soldan, M.D., Ph.D. – Clinical MS fellow (2012 to 2014)
• Eoin Flanagan, M.B.B. Ch. – Clinical MS fellow (2012 to 2013)
• Craig M. Nelson, Ph.D. - RTP Research Fellow (2012)
• William Oliver Tobin– Clinical MS fellow (2014)

Administrative Responsibilities

• Member - Department of Neurology Research Committee (1986-1994)
• Chairman - Department of Neurology Research Committee (1990-1994)
• Member - Mayo Staff Development Liaison Committee (1987-1991)
• Member - Department of Neurology Academic Promotions Committee (1988-2005)
• Member - Neuropathology Search Committee (1988-1991)
• Member - Department of Neurology, Postgraduate Education Committee (1983-1987)
• Member - Virology Search Committee (1989-1991)
• President - Southern Minnesota Chapter of the Society for Neuroscience (1989-1991)
• Member - Personnel Subcommittee of the Mayo Institutional Research Committee (1990-1991)
• Member - Research Advisory Panel - Mayo Clinic Jacksonville (1989-1993)
• Member - Search Committee for Chairman of Department of Immunology (1990-1991)
• Member - Resident Selection Committee, Department of Neurology (1990-1995)
• Member - Administrative Executive Committee, Department of Neurology (1990-1994)
• Member - Resident Recruitment Committee, Department of Neurology (1992-1995)
• Member - Clinical Drug Trials Task Force, Department of Neurology (1992-1995)
• Member - Visiting Faculty Committee, Department of Neurology (1988-present)
• Member - Human Genetics Task Force, Mayo Institutional Research Committee (1992-1993)
• Member - Balfour-Kendall Alumni Awards Committee (1993)
• Chairman - M.D/Ph.D. Program Admissions Committee, Mayo Medical School (1995-2007)
• Member - Mayo Institutional Research Committee (1995 - 1998)
• Member - Research Resource Facility Subcommittee of the Mayo Rochester Research Committee (1995-1998)
• Member -Administrative Executive Committee, Department of Neurology (1998-2005)
• Vice-Chair -Academic Affairs for Department of Neurology (1998-2005)
• Chairman - Division of Neuroimmunology (1998-2002)
• Chairman -Multiple Sclerosis Subspecialty Group (1998-2002)
• Chairman - Division of Demyelinating Disorders (2003-2004)
• Program Director – Mayo MSTP Program (Medical Scientist Training Program; M.D./Ph.D.) (2003-2007)
• Member, Center for Translational Science Activities (CTSA) Metabolomics Development Oversight Group (2009)

Presentations at Meetings

Intramural Presentations

• 12/06 – Neurology Grand Rounds – “Harnessing the Natural Immune Repertoire to Induce CNS    Repair”
• 3/10 – Mayo Clinic Young Investigator Research Symposium – “25 Years of Applying Basic Science Principles to Clinical Care”
• 6/10 –Mayo MD-PhD Student & Faculty Retreat: Keynote Speaker – “My Road to Science”
• 4/13 – Speaker for the Center of Multiple Sclerosis and Demyelinating Diseases – “From Conception to Birth: Moving a Basic Principle to Possible Clinical Utility”
• 10/13 Immunology Grand Rounds – “Human Autoantibodies in the Treatment of Central Nervous System Disease”

National Meetings

• 5/85 - National Multiple Sclerosis Society, Minnesota Chapter (Rochester, MN) - "Update on Multiple Sclerosis"
• 3/87 -Mayo Alumni Association (Orlando, FL) - "Interactions Between Central Nervous System Viruses and the Immune System"
• 6/87 - American Association of Neuropathologists: Course in Neuroimmunology (Seattle,WA) - "Neuroimmunologic Analysis of Nervous System Viral Infection"
• 9/87 - Plenary Session at the Second International Congress of Neuroimmunology (Philadelphia, PA) - "Virus Induced Demyelination"
• 6/88 - American Board of Neurology and Psychiatry - Examiner
• 9/88 - Seventy-fifth Anniversary of the Department of Neurology, Mayo Medical School (Rochester, MN) - "Current Theories of Multiple Sclerosis Pathogenesis"
• 11/88 - National Multiple Sclerosis Society, Workshop on Therapeutic and Diagnostic Trials in Multiple Sclerosis (Jekyll Island, GA) - "Stimulation of Remyelination"
• 5/89 - Invited Speaker, Searle Scholars Meeting (Chicago, IL) -  "Mechanisms of Differential Susceptibility to Theiler's Virus-induced Demyelination"
• 3/90 - Invited Speaker, National Multiple Sclerosis Society - Workshop on the Role of Astrocytes in Inflammatory Demyelination (Galveston, TX) - "Viral Disease in Animals and Man"
• 4/90 - Research Seminar, Centocor (Malvern, PA) - "Demyelination and Remyelination"
• 7/91 - Invited Speaker, United Leukodystrophy Foundation, University of Chicago (Chicago, IL) - Invited by Dr. Hugo Moser, "Immunoglobulin Therapies"
• 10/91 - Minnesota Society of Neurosciences (St. Paul, MN) - "Demyelination and Remyelination in Multiple Sclerosis"
• 10/91 - 56th International Meeting of the Mayo Alumni Association (Rochester, MN) -"Electron Microscopic Pathology of Multiple Sclerosis"       
• 9/92 - Research Society of the Mayo Medical School, "Demyelination and Remyelination in the Central Nervous System"
• 7/92 - Invited Speaker, Gordon Research Conference on Myelin (Plymouth, NH) - "Class I MHC Gene Production and the Development of Demyelination".  Invited by Dr. Howard Lipton
• 10/92 - Invited Speaker, Plenary Session at the 117th Annual Meeting of the American Neurological Association (Toronto, Canada) - "Human Class I Major Histocompatibility Complex Transgene Abrogates Demyelination Induced in Mutant B10.D2dm1 Mice"
• 10/92 - Invited Speaker, Advances in the Understanding and Treatment of Multiple Sclerosis.  Sponsored by: International Business Communications (Boston, MA)-"Role of Immunoglobulin G (IgG) in Regrowth of Myelin"
• 2/94 - Invited Speaker, Viral Pathogenesis Symposium Scripps Clinic in Honor of Michael B. A. Oldstone (La Jolla, CA) - "Virus-Induced Demyelination and Remyelination"
• 3/94 - Invited Speaker, Gordon Research Conference on Myelin (Casa Serena, Oxnard, CA)- "Immune-Derived Factors Affecting Demyelination and Remyelination".  Invited by Dr. Jean Merrill.
• 8/95 - Invited Speaker, Fourth Biennial Ray and Robert Kroc - UCONN Symposium on Neurology (Farmington, CT).  "Promotion of CNS Remyelination with Monoclonal Antibodies."  Invited by Dr. Steve Pfeiffer.
• 2/98 - Invited Speaker, Gordon Research Conference on Myelin (Ventura, CA).  “The Role of Class I MHC Immune Function in Development of Neurologic Deficits Following Demyelination.”  Invited by Dr. Bruce Trapp.
• 7/98 - Invited Speaker, FASEB Conference (Portland, OR) – “Neuro-Immune Interaction in Injury and Disease” and "The Role of the Immune Response in Demyelination and Remyelination in a Viral Model of Multiple Sclerosis."   Invited by Drs. Ronald P. Hart and Dr. Michal Schwartz.
• 1/99 - Invited Speaker, Keystone Symposia - Immunogenetics of Human Disease (Taos, New Mexico).  "Viral-Induced Demyelination: A Model of MS."  Invited by Dr. Chella David.
• 3/99 - Invited Professor, Vanderbilt University - Brain Awareness Initiative.  "Is it Possible to Promote New Myelin Repair in Multiple Sclerosis."  Invited by Dr. Marcie W. Pospichal.
• 10/99 - Invited Speaker, American Neurological Association, Seattle, WA.  "Pathogenesis of Multiple Sclerosis."  Invited by Dr. Eva Feldman.
• 10/99 - Invited Speaker, Second Santa Fe Symposium on "In Defense of the Brain", Santa Fe, New Mexico.  “Critical Immune Factors in Resistance to Theiler’s Murine Encephalomyelitis Virus”.
• 04/02 - Invited Speaker - Charleston, South Carolina Symposium.  "Multiple Sclerosis - Prospects for CNS Repair".  Invited by Dr. Michael Oldstone.  3rd Pfizer Symposium on Immunopathogenesis of Infections and Inflammatory Diseases of the Brain.
• 03/04 - Invited Professorship – Blood Research Institute, Medical College of Wisconsin.  “Pathogenesis of Multiple Sclerosis – New Approaches for Remyelination”.  Invited by Dr. Bonnie Dittel.
• 09/05 – Invited Lecture, University of California at San Diego. “Novel Therapies for MS”. San Diego CA.
• 09/05 – Invited Lecture, American Neurologic Association. “Mentoring and Being Mentored.” San Diego, CA
• 3/07 – Invited Speaker, Mayo Sponsored CME Course.  “Multiple Sclerosis: Update and Practical Management.”  “Advances in Repair and Remyelination in Multiple Sclerosis.”  Invited by Dr. Dean Wingerchuck, Scottsdale, AZ.
• 04/08 – Keynote Speaker, American Academy of Neurology Plenary Session, Frontiers in Neuroscience. “Natural Autoantibodies in the Treatment of Neurologic Disease.” Chicago, IL.
• 02/11 – Keynote Speaker, National Multiple Sclerosis Society, Minnesota Chapter, Winter Research Symposium. “New Discoveries and Therapies in MS.” St. Cloud, MN.
• 03/12 – Session Chair, Oldstone Scientific Symposium, Scripps Research Institute, La Jolla, CA.

International Meetings

• 11/91 - Guest Lecturer, European Charcot Foundation (Abbaye de Rayaumont, France).  Invited by Dr. N. Bauman.
• 10/92 - Invited Speaker, 8th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (Barcelona, Spain) - "Disability in Multiple Sclerosis."   Invited by Dr. Fernandez.
• 4/93 - Visiting Lecturer, Annual Meeting of the Royal College of Physicians of Thailand (Pattaya, Thailand) - "Innovative New Therapies in the Treatment of Immune-mediated Disorders" and "The Pathogenesis of Multiple Sclerosis."   Invited by Dr. N. Poungvarin, Professor of Neurology.  
• 9/93 - Invited Speaker, 5th International Meeting of the Myelin Project, Rome, Italy - "Immunoglobulin Treatment for Remyelination."  Invited by A. Odone.
• 12/93 - Invited Speaker, Fifth International Symposium on Neural Regeneration (Asilomar Conference Center (Pacific Grove, California) - "Promotion of Central Nervous System Remyelination with Monoclonal Antibodies."  Invited by Dr. Frederick J. Seil.
• 5/94 - Invited Speaker, Multiple Sclerosis Symposium of The Turkish Neurological Society, Istanbul, Turkey - "Basic Concepts of Demyelination and Remyelination", "Epidemiology of Multiple Sclerosis", and "Acute Optic Neuritis in Olmsted County, Minnesota."  Invited by Dr. Axel Siva.
• 4/95 - Invited Participant, First Myelin Project Clinicians Meeting - Florence, Italy.  Invited by A. Odone.
• 8/95 - Invited Speaker, National Multiple Sclerosis Society Workshop on Genetic Models of Multiple Sclerosis and Related Disorders.  "Genetic Basis of Theiler's Virus-Induced Demyelination" (Quebec City, Canada).  Invited by Dr. Stephen C. Reingold.
• 8/95 - Invited Speaker, Meeting on Cellular and Molecular Mechanisms of Regeneration and Functional Repair in the CNS, University of Osnabruck, Germany.  "Strategies to Promote CNS Remyelination in Vivo."  Invited by Drs. G. Jeserich and H. H. Althaus.
• 3/96 - Invited Speaker, 28th Annual USGEB - Meeting, University of Zurich, Switzerland. "Theiler's Virus-induced Demyelination in Immune Knockout Mice: A Model for Multiple Sclerosis."  Invited by Dr. A. Fontana.
• 3/96 - Invited Speaker, Department of Neurology, University of Zurich, Zurich, Switzerland. "Remyelination in Multiple Sclerosis and Animal Models." Invited by Dr. A. Fontana.
• 6/96 - Invited Speaker, Fourth Altschul Symposium, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.  "Evolving Biological Concepts and Therapeutic Approaches in the Treatment of Demyelinating Diseases."  Invited by Dr. B. H. J. Juurlink.
• 7/96 - Invited Speaker, European Charcot Foundation.  Symposium on Remyelination in Multiple Sclerosis (Vienna, Austria).  "Central Nervous System Remyelination in Rodents."  Invited by Prof. Otto R. Hommes, Chairman of the European Charcot Foundation. 
• 1/97 - Invited Discussant - Workshop on the “Role of Magnetic Resonance Technique in Understanding and Managing Multiple Sclerosis”, Oxford, England.  Invited by Dr. Stephen C. Reingold.
• 5/97 - Invited Speaker (Plenary Session), First International Symposium of Neurovirology, Philadelphia, PA.  “The Role of CD4+ and CD8+ T Cells in Demyelinating Disease Following Theiler’s Virus Infection: A Model for Multiple Sclerosis.”  Invited by Dr. Kamel Khalili.
• 9/97 - Invited Speaker (Plenary Session), XVI World Congress of Neurology, “Therapeutic Approaches to Prevention and Recovery from Multiple Sclerosis”, Buenos Aires, Argentina.   Invited by Dr. Jack P. Antel.
• 9/97 - Invited Speaker (Satellite Symposium on Multiple Sclerosis), XVI World Congress of Neurology, “Animal Models of Multiple Sclerosis”, Buenos Aires, Argentina.  Invited by Dr. Calos Bardeci.
• 4/98 - Invited Speaker, Society for General Microbiology, University of Nottingham, Nottingham, UK. “Demyelination in a Viral Model of Multiple Sclerosis.”  Invited by Dr. W. L. Irving. 
• 5/98 - Invited Speaker, Second Congress of Molecular Medicine, Berlin, Germany.  Symposium: “Immunosuppression and Modulation: Will There be a Cure for Multiple Sclerosis?”, “Remyelination in Multiple Sclerosis – Implications for New Therapeutic Strategies.”  Invited by Dr. Klaus Felgenhauer.
• 8/98 - Invited Speaker, International Congress of Neuroimmunology, Montreal, Canada.  "Autoimmunity and CNS Remyelination."  Invited by Dr. Jack Antel. 
• 2/99 - Invited Speaker, ASEAN Neurological Association and the Neurological Society of Thailand.  "Pathogenesis of Multiple Sclerosis" and "Promotion of CNS Remyelination."  Invited by Dr. Naraporn Prayoonwiwat and Dr. Prasert Boongird.
• 8/99 - Invited Speaker, International MS Workshop – Demonstrating Infectious Cause: Viral and Bacterial Infections in MS and Related Disorders.  “Theiler’s Virus Demyelination”, Brighton, England.  Invited by National Multiple Sclerosis Society.
• 10/99 - Invited Speaker, MS Workshop, "Demyelination and Neurologic Deficits", Venice, Italy.  Invited by Prof. Otto Hommes, Chairman, European Charcot Foundation.
• 3/00 - Invited Speaker, 12th MS Forum Workshop,  "Remyelination in Multiple Sclerosis", Athens, Greece.
• 6/00 - Invited Speaker, Multiple Sclerosis 2000, "Infection and Experimental Models of CNS Demyelination", Turku, Finland.  Invited by Dr. Aimo Salmi and Dr. Tom Gronberg
• 6/00 - Invited Speaker, Pre Congress Satellite of the European Neurological Society, Immune-Mediated Brain Injury and Repair: Mechanisms and Therapies, "Antibody-Mediated Remyelination", Haifa, Israel.  Invited by Dr. Ariel Miller.
• 9/00 - Invited Speaker, International Neuropathology Congress, "Pathology of Virus-induced Demyelination", Birmingham, England.  Invited by Dr. Bill Blakemore.
• 2/02 - Invited Speaker, The Japanese Society of Neuroimmunology.  "Pathogenesis of Multiple Sclerosis".  Invited by Dr. Gen Sobue, Tokyo, Japan.
• 8/02 - Invited Speaker, Benzon Symposium No.49.  “Multiple Sclerosis: Genetics, Pathogenesis, and Therapy.”  Invited by Arne Svejgaard, Copenhagen, Denmark.
• 10/02 - Invited Speaker, International Workshop on Repair of the Central Nervous System – Mechanism and Potential for Recovery of Function in Multiple Sclerosis and Related Disorders.  Invited by National Multiple Sclerosis Society, Nice, France, October 5-7, 2002.  “Monoclonal Antibodies to Aid Remyelination”
• 9/04 – Invited Speaker, 6th International Symposium of Neurovirology. “Role of MHC Class I Restricted T Cells in Inducing Neurologic Injury”.  Invited by International Society of Neurovirology, Alghero, Sardinia, Italy, September 13, 2004.
• 2/06 - Invited special speaker to the Gordon Conference on Myelin - “CNS repair and remyelination in MS with the use of natural human monoclonal antibodies" Invited by Richard Rudick, Ventura, CA, February 16, 2006.
• 10/07 – Invited Speaker, International Workshop on Naturally Occurring Antibodies in Health and Disease – “Natural antibodies in the treatment of multiple sclerosis.” Bern, Switzerland, October 19-20, 2007.
• 3/09 – Invited Speaker, 6th International Immunoglobulin Symposium, Interlaken, Switzerland “Natural Autoantibodies in the treatment of multiple sclerosis.”
• 10/09 – Invited Speaker, World Congress of Neurology 2009, Bangkok, Thailand  “Repair Strategies in Multiple Sclerosis.”
• 4/10 – Invited Speaker, Clinical Neuroimmunology Symposium, Antalya, Turkey, “How should a good scientific project be prepared?” and “Human natural autoantibodies in the treatment of neurologic diseases.” April 28 – May 2, 2010.
• 4/13  - Invited Plenary Speaker – Neuroimflammation Symposium – University of Toronto- Toronto, Canada- “Therapeutic Approaches to CNS Repair” Invited by Dr. Ann Yeh, April 17th to April 19th , 2013
• 6/13 – Invited Plenary Speaker – 2nd Internationl Conference and Exhibition on Neurology and Therapeutics-Chicago, IL, ” A Recombinant Human IgM prevents neuronal injury in multiple animal models of CNS disease” June 17-19, 2013

  Invited Presentations and Visiting Professorships

• 9/82 - Northwestern University Medical School, Department of Neurology (Chicago, IL) Invited by Dr. Donald Harter, "Viral Persistence in the CNS"
• 2/85 - University of Minnesota, Neurobiology Conference (Minneapolis, MN) - Invited by Dr. Gary Birnbaum, "Demyelination by Viruses"
• 10/87 - Visiting Professor, Institute of Neurology, Queens Square, University of London, England - "Virus-Induced Demyelination and Remyelination"
• 10/87 - Visiting Professor, Institut Pasteur (Paris, France), - "Role of Class I and Class II-Restricted T Cells in Demyelination Induced by Theiler's Virus."  Invited by Dr. M. Brahic.
• 1/88  - Visiting Professor, University of Western Ontario, Visiting Faculty (London, Ontario), - "Theiler's Virus as a Model for Demyelination."  Invited by Dr. S. Dales.
• 2/89 - Visiting Professor, University of Minnesota, Department of Microbiology (Minneapolis, MN) - Invited by Dr. Ashley Haase, "Theiler's Virus-Induced Demyelination"
• 9/90 - Visiting Professor, Neurology Rounds, Tenri Hospital - Nara, Japan.   Invited by Dr. Koizumi.
• 11/90 - Visiting Professor and invited speaker, Istanbul University, National Congress of Neurology (Istanbul, Turkey), - "Pathogenesis of Immune-Mediated Demyelination and Remyelination."  Invited by Dr. H. Denktas.
• 11/91 - Visiting Professor, Institute of Neurology, University Hospital Nijmeje (Nijmegen, The Netherlands) - "Demyelination and Remyelination in Multiple Sclerosis and in Viral-induced Models."   Invited by Dr. O. Hommes.
• 11/91 - Visiting Professor, Hospital de la Salpetrière (Paris, France), - "Demyelination and Remyelination in Multiple Sclerosis and in Viral-induced Models."   Invited by Dr. N. Bauman.
• 11/91 - Visiting Professor, Max-Plank Institute, Abteilung Neuroimmunologie (Munich, Germany) - "Demyelination and Remyelination in Multiple Sclerosis and in Viral-induced Models."  Invited by Drs.Wekerle and C. Linnington.
• 1/91 - Visiting Professor, Institut Pasteur (Paris, France) - "Mechanisms of Resistance and Susceptibility to Theiler's Virus Infection."  Invited by Dr. M. Brahic.
• 3/91 - Visiting Professor, University of Alabama, Department of Neurology (Birmingham, AL) - Invited by Dr. John Whitaker, "CNS Demyelination and Remyelination in MS and in Animal Models"
• 3/91 - Visiting Professor, Mayo Clinic (Scottsdale, AZ) - Invited by Dr. Jonathan Carter, "Mechanism of CNS Demyelination and Remyelination"
• 10/91 - Visiting Professor, Henry Ford Hospital (Detroit, MI) - Invited by Dr. Stanton Elias, "Demyelination and Remyelination in Multiple Sclerosis"
• 3/92 - Visiting Professor, University of Wisconsin (Madison, Wisconsin) - Department of Neurology - Invited by Dr. Henry S. Schutta, "Promotion of CNS Remyelination in Multiple Sclerosis"
• 12/92 - Visiting Professor, Mayo Clinic Jacksonville - Invited by Dr. Neath Folger, Grand Rounds "CNS Demyelination and Remyelination"
• 2/93 - Visiting Professor, Department of Microbiology, University of Pennsylvania (Philadelphia, PA).  Invited by Drs. Patterson and S. Weiss - "Genetic Basis of Demyelination"
• 4/93 - Visiting Professor, Department of Neurology, Nagoya University (Nagoya, Japan) - "Pathogenesis of Multiple Sclerosis."  Invited by Drs. K. Ohtani and A. Suzumura.
• 4/93 - Visiting Professor, Department of Neurology, Siriraj Hospital Mahidol University (Bangkok, Thailand) - "The Epidemiology of Multiple Sclerosis in Olmsted County" and "Treatment of Multiple Sclerosis."   Invited Drs. N. Poungvarin and N. Prayoonwiwat.
• 6/93 - Visiting Professor, Department of Neurology, University of California at San Diego (San Diego, CA).  Invited by Dr. Weiderholt - "CNS Demyelination and Remyelination"
• 12/94 - Visiting Professor, Montreal Neurologic Institute (Montreal, Canada).  Pathogenesis of Viral CNS Infections."  Invited by Dr. Jack Antel.    
• 9/95 – Visiting Professor, The University of Texas - Houston Medical School - "Multiple Sclerosis Update 1995" (Houston, TX).  "The Possible World of Viruses."  Invited by Dr. Jerry Wolinsky. 
• 1/96 - Visiting Professor, New York University, Department of Neurology (New York, NY).  "Natural Autoantibodies Promote Remyelination." Invited by Dr. Wise Young and Dr. Patrick Kelly.
• 8/96 - Visiting Professor, Cleveland Clinic - Neuroscience Department (Cleveland, OH).  "Promotion of CNS Remyelination by Natural Autoantibodies."  Invited by Dr. Bruce Trapp.
• 1/97 - Visiting Professor - Departments of Neurology and Veterinary Medicine, Cambridge University, Cambridge, England.  “Promotion of Remyelination with Natural Autoantibodies.”  Invited by Drs. Alastair Compston, Neil Scolding, and William Blakemore.
• 2/97 - Invited Professor, Center for Research in Neuroscience, McGill University, Montreal, Canada.  “Strategy to Enhance Myelin Repair in the CNS with Natural Autoantibodies.” Invited by Dr. Sam David.  
• 3/97 - Visiting Professor, Texas A&M (College Station, Texas) - Pathology Department.  “Genetic Basis of an Animal Model of Multiple Sclerosis.”  Invited by Dr. Julian Leibowitz.
• 5/98 - Visiting Professor, University of Göttingen, Germany. “Promotion of Remyelination by Natural Autoantibodies.”  Invited by Dr. Wolgang Brück.
• 2/99 - Visiting Professor, University of Pennsylvania, Philadelphia, PA.  "Development of Neurologic Deficits in a Viral Model of MS."  Invited by Dr. Patterson.
• 3/99 - Visiting Professor, Neurology Grant Rounds - Department of Neurology, Vanderbilt University.  "Pathogenesis of Multiple Sclerosis."  Invited by Dr. Ram Sriram.
• 5/00 - Visiting Professor, Scripps Research Institute (La Jolla, CA) - "Role of Class I MHC in Demyelination and Neurologic Deficits".  Invited by Drs. Michael Buchmeir and Michael Oldstone. 
• 01/01 - Honorary Peter Lambert Memorial Lecture - University of California in San Diego.  "Human Antibodies Promote CNS Repair".  Invited by Dr. Harry Powell.
• 01/01 - Invited Professor - Department of Neurosciences - University of North Carolina in Chapel Hill.  "Critical Role of MHC Class I in Demyelination and Neurologic Deficits".  Invited by Dr. William Snyder.
• 02/01 - Invited Professor, Department of Neuroscience - University of California at Irvine.  "Remyelination using Human Monoclonal Antibodies".  Invited by Dr. Tom Lane.
• 11/01 - Visiting Professor, Departments of Immunology and Microbiology - University of Iowa, Iowa City, IA.  "Role of Class I-Restricted T Cells in Demyelination and Neurologic Deficits".  Invited by Dr. Stan Pearlman.
• 2/02 - Visiting Professor, University of Kyushu.  Invited by Prof. Kira, Fukuoka, Japan.
• 2/02 -Visiting Professor, University of Kagoshima.  Invited by Drs. Fukunaga and Osame, Kagoshima, Japan.
• 2/02 - Visiting Professor, University of Nagasaki.  Invited by Prof. Nakamura, Nagasaki, Japan.
• 11/02 - Visiting Professor, Department of Neuroscience at the University of Medicine and Dentistry of New Jersey, Newark, New Jersey.  “Pathogenesis of Multiple Sclerosis”.  Invited by Dr. Peter Dowling and Dr. Stuart Cook.
• 2/03 – Invited Speaker, Mayo Sponsored CME Course.  “Multiple Sclerosis: Advances and Evidence-based Management.”  “Repair and Remyelination in Multiple Sclerosis.”  Invited by Dr. Dean Windgerchuck, Scottsdale, AZ.
• 2/03 – Invited Speaker, Multiple Sclerosis Society of Sacramento – Professional Advisory Committee.  “Pathogenesis of Multiple Sclerosis – Prospects for CNS Repair.”  Invited by Dr. John Schafer, Sacramento, CA.
• 2/03 – Invited Professor, Department of Neurology, University of California, Davis Medical Center, Sacramento, CA.  “Human Monoclonal Antibodies for Promotion of Myelin Repair.”  Invited by Dr. Ellen Yee.
• 2/03 – Invited Speaker, Multiple Sclerosis Society of Santa Barbara.  “Pathogenesis of Multiple Sclerosis – Prospects for CNS Repair.”  Invited by Dr. Robert Harbough.
• 3/04 – Invited Visiting Professor, University of Puerto Rico Medical School.  “Pathogenesis of Multiple Sclerosis: Prospects for Immune-mediated Remyelination.”  Invited by Dr. Miriam Marquez.
• 03/04 Invited Visiting Professor, University of Puerto Rico Medical School. – San Juan “Mayo – University of Puerto Rico Combined M.D./Ph.D. Program”.  Invited by Dr. Miriam Marquez.
• 01/05 Invited Visiting Professor, University of Pennsylvania, Philadelphia, Pennsylvania.  “Demyelination in Multiple Sclerosis”.  Invited by Dr. Francisco Gonzalez-Scarano.
• 03/05 Invited lecture, Mayo Clinic, Multiple Sclerosis Symposium, Scottsdale, AZ. “Regeneration in Multiple Sclerosis,” Invited by Dr. Dean Wingerchuk.
• 11/05 Invited Visiting Professor, University of Cincinnati, Cincinnati OH, “Pathogenesis of MS and Remyelination,” Invited by Istvan Pirko.
• 3/06 - Invited speaker to the National Institutes of Health- Neurological Disorders. Rockville, Maryland "CNS repair by use of human antibodies," Invited by Dr Woodberry-Harris.
• 3/06 - Visiting professorships at University of California in Santa Barbara, UCLA, Loma Linda University, Chapters of the National Multiple Sclerosis Societies in Southern California." Pathogenesis and Treatment of Multiple Sclerosis" Invited by David W. Brandes, MS, MD, FAAN Chairman, Board of Directors, Northridge Foundation for Neurological Research and Education Asst. Clinical Professor, UCLA Director, Northridge MS Center.
• 4/06 - Visiting Professorship at the University of California in San Diego, "Heterorogeneity of Multiple Sclerosis” Invited by Dr. Douglas Galasko.
• 06/06 – Invited Lecture, Animal Models of Human Autoimmune Disease. "Role of Human MHC Class I and Class II genes in the Theiler's model of Multiple Sclerosis." Park City, UT; invited by Dr. Chella David.
• 05/07 – Invited Lecture, NIH Infectious Disease Imaging Interest Group.  “Monoclonal antibodies directed against oligodendrocytes to induce CNS repair” Bethesda, MD; invited by Dr. Richard Pilcher.
• 02/08 – Visiting Professor at the University of New Jersey Medical School, Newark NJ, “Natural antibodies in the treatment of multiple sclerosis,” Invited by Dr. Andrew Pachner.
• 04/08 – Invited Lecturer, Fast Track – Genentech, San Francisco, CA. "Natural antibodies as novel therapies in Medicine"
• 01/09 - Invited Lecturer, and Advisory Member – Faster Cures- The Center for Accelerating Medical Solutions, Washington DC.  “Advances in Multiple Sclerosis”
• 03/09 – Invited Lecturer, Multiple Sclerosis CME Course – Scottsdale AZ “Remyelination and Neural Protection in Multiple Sclerosis”
• 03/09 - Visiting Professor at the University of Louisville, Louisville, KY, “Pathogenesis of Multiple Sclerosis” and “ Germline Immunoglobulins in the treatment of neurologic disease”
• 04/10 – Invited Speaker, Acorda Therapeutics, Inc., Hawthorne, NY. “Human Natural Autoantibodies for the Treatment of Neurologic Disease.” 
• 05/10 – Invited Lecture, Grand Rounds – University of Minnesota, Minneapolis, MN. “Human Natural Autoantibodies for the Treatment of Neurologic Disease.” 
• 05/11 – Visiting Professorship at University of Montana, Missoula, MT, “Promotion of Repair of Spinal Cord Axons in vivo by Human Natural IgM Antibodies”
• 2/13 – Visiting Professorship Multiple Sclerosis Research Center of New York, New York, New York.  “Grand Rounds – Multiple Sclerosis Research Center of New York” invited by Dr. Saud Sadiq.
• 2/13 – Invited Lecture 2013 Mayo MS CME Course “Multiple Sclerosis 2013: Update and Practical Management” Scottsdale, Arixona “Remyelinating and Repair Strategies in MS” invited by Jonathan Carter and Dean Wingerchuck.
• 3/13 – Invited Lecture American Academy of Neurology by Acorda Therapeutics “ Human Natural Autoantibody (rHIgM22) for Remyelination in Multiple Sclerosis” invited by Dr. Anthony Caggiano.
• 1/14 – Invited Lecture, Neurology Grand Rounds , Northwestern University School of Medicine“Human Recombinant Natural Auto-antibodies in the Treatment of Neurologic Disorders”

Clinical Practice Interests and Accomplishments

• Multiple sclerosis, demyelinating disorders, neurovirology, neuroimmunology, autoimmune paraneoplastic diseases

Research Activities

• Viral persistence, central nervous system demyelination, remyelination, immunogenetics, virus-host interactions, experimental neuropathology, viral models of demyelination, neuroepidemiology of multiple sclerosis

Research Grants Awarded

• "Mechanisms of Viral Induced Demyelination", Teacher Investigator Award, National Institutes of Health - NS00849.  Principal Investigator (12/83-11/88).
• "Development of a Spinal Animal Model of Meningeal Carcinomatosis", Fraternal Order of Eagles National Cancer Fund.  Co-Principal Investigator with Dr. G. Powis (4/84-4/85).
• "Molecular Characterization of B-Lymphocyte Abnormalities in Ataxia-Telangiectasia Model", Fraternal Order of Eagles National Cancer Fund.  Co-Principal Investigator with Dr. G. E. Woloschak (4/86-4/87).
• "Tumor Immunology and Immunoregulation", National Institutes of Health Training Grant, CA09127-12. Co-Investigator (C. S. David, Program Director), (7/86-7/95).
• "Immune Promotion of Remyelination", National Multiple Sclerosis Society, RG 1878-A-1.  Principal Investigator (10/86-10/89).
• "Searle Scholars Award" - Chicago Community Trust.  Principal Investigator (9/86-9/90).
• "Multiple Sclerosis in Olmsted County, 1950-1984:  A population based investigation of the possible association with diabetes mellitus, autoimmune diseases, neoplastic disorders and head trauma" Project 2 - NS17750-P2.  Principal Investigator – Rochester Neuroepidemiology Program Project, National Institutes of Health. (L. T. Kurland, Director) (12/81-6/92).
• "Immune Promotion of Remyelination", National Institutes of Health, RO1- NS24180.  Principal Investigator (9/87-9/95).
• "Theiler's Virus-induced Demyelination and Remyelination", National Multiple Sclerosis Society, RG-1878-B-2.  Principal Investigator (9/89-4/93).
• "Immunopathology of Demyelination", National Multiple Sclerosis Society, RG 2174-A-3.  Principal Investigator (4/90-9/93).
• "Promotion of CNS Remyelination by Immunoglobulin in Myelin Deficient-Mutant Mice", The Myelin Project, Myelin Project #1.  Principal Investigator (4/92-9/95).
• "Development of an Animal Model for Multifocal Inflammatory Demyelination Induced by 5-Fluorouracil and Levamisole" - Mayo Foundation.  Co-Principal Investigator with Dr. David W. Kimmel (6/92-6/93).
• "Disability in Multiple Sclerosis: A Population-based Study in Olmsted County" – Mayo Foundation, MS #1.  Principal Investigator (9/92-9/93).
• "Fellowship in Neuroscience", Applebaum Family Support Foundation, Principal                             Investigator (6/93-Present).
• "Intravenous Immunoglobulin Therapy in Multiple Sclerosis", Co-investigator.  J. Noseworthy, Principal Investigator.  National Multiple Sclerosis Society, RG 2520-A-1 (4/1/93-3/31/94).
• "Novel Strategies to Promote Remyelination in the Central Nervous System", Peterson Grant #1, Principal Investigator (1/1/93-12/31/95).
• "Disability and Rehabilitation Utilization Patterns in Multiple Sclerosis: A Population-based Study in Olmsted County, Minnesota",  National Multiple Sclerosis Society, MS #2, Principal Investigator (7/93-7/94).
• "Growth of Human Oligodendrocyte Progenitors In Vitro", Mayo Foundation, Co-principal Investigator with S. Hunter (1/94-12/97).
• "Patterns of Health Care Service Utilization by Multiple Sclerosis Patients in Olmsted County, MN: A Population-Based Study", Co-principal Investigator with K. Stolp-Smith.  National Multiple Sclerosis Society, MS #3, (1/94-12/95).
• "Isolation and Characterization of MHC-bound Self Peptides in Autoimmune Disease", National Institutes of Health, NIH-NO1-AI-4-5197-02, Co-investigator with Dr. Peter Wettstein (3/94-2/99).
• "Theiler's Murine Encephalomyelitis Virus Induced Demyelination in Normal and Mutant Mice", Multiple Sclerosis Society of Canada.  Co-investigator with Dr. Tak W. Mak of the Ontario Cancer Institute/Princess Margaret Hospital (4/93-3/95).
• "Intravenous Immunoglobulin in Multiple Sclerosis: Advanced MRI Studies", Myelin Project.  Co-principal Investigator with Dr. John Noseworthy (3/94-3/95).
• "Intravenous Immunoglobulin in Multiple Sclerosis".  Co-investigator with Dr. John Noseworthy, National Institutes of Health, R01-NS-31506-01-A1 (4/94-3/98).
• "T Cell Function in a Murine Model of Multiple Sclerosis", National Institutes of Health,                          R01 NS32129.  Principal Investigator (8/94-7/99).
• "Intravenous Immunoglobulin Therapy in Optic Neuritis", National Institutes of Health, R01 - U10EY10963-01.  Co-Principal Investigator with Dr. John Noseworthy (4/95-3/98).
• "Immune Promotion of Remyelination", National Multiple Sclerosis Society.  Principal Investigator (10/95-9/98).
• "Immune Promotion of Remyelination", National Institutes of Health, R01 NS24180.  Principal Investigator (10/87-10/09).
• "Promotion of Remyelination in Spinal Cord Injury", American Paralysis Association, #RA2-9503.  Principal Investigator (1/1/96-12/31/97).
• "Pre-Clinical Studies of a Monoclonal Antibody Designed to Promote Central Nervous System Repair", Acorda Therapeutics, Inc.  Principal Investigator (10/1/95-9/30/98).
• “Molecular Characterization of Antibody-Induced Remyelination”, Acorda Therapeutics. (4/98-3/01).
• "Plasma Exchange in Severe Demyelinating Disease", National Institutes of Health, R01 NS32774. Co-investigator with Dr. Brian Weinshenker (6/97-6/99).
• “Myelin Repair in Multiple Sclerosis” Applebaum Foundation, Principal Investigator (6/97-6/01).
• "T Cell Function in a Murine Model of Multiple Sclerosis" National Institute of Health, R01 NS32129.  Principal Investigator (8/99 - 12/10).
• "Optimization of Antibody Enhanced Remyelination", National Multiple Sclerosis Society, RG 3172-A-6.  Principal Investigator (04/00-03/08).
• "Immunogenetics of Demyelination" - Program Project Director, National Institutes of Health, P01-NS38468.  "Effect of Transgenic Expression of Theiler's Virus Coding Region on Pathogenesis" - Principal Investigator, Project 1 of "Immunogenetics of Demyelination" Program Project (07/00-06/05).
• "Human Monoclonal Antibodies for CNS Remyelination", National Institutes of Health, R41 NS40172-01.  Principal Investigator (12/01/00-11/30/02).
• "Human Antibodies to Promote CNS Regeneration", National Institutes of Health, R43 NS40209-01.  Co-Investigator with Dr. Timothy Neuberger from Acorda Therapeutics (12/01/00-11/30/02).
• "Remyelination in Multiple Sclerosis: Neural Precursor-Based Repair", MS Research Foundation of Canada.  Principal Investigator, Project 4 under the supervision of Dr. Jack Antel (10/01-10/04).
• "Human Monoclonal Antibodies for CNS Remyelination", Phase II STTR grant from National Institutes of Health, Allan Bieber - Principal Investigator with Acorda Pharmaceuticals (9/02-9/05).
• “Mayo MSTP M.D./Ph.D. Program”, National Institutes of Health, T32GM65841-01.  Principal Investigator (7/03-7/07).
• National Multiple Sclerosis Society Collaborative Research Center Grant (4/04-4/13), Moses Rodriguez, Principal Investigator. 
• “Genetic Analyses of Spontaneous Remyelination”, National Multiple Sclerosis Society (10/03-9/05), Allan Bieber, Principal Investigator; Moses Rodriguez, Co-investigator.
• “Measles Viruses with Added Vaccines”.  National Institutes of Health, R01-A157761.  Dr. Cattaneo, Principal Investigator; Moses Rodriguez, Co-investigator.
• “A Recombinant Human Monoclonal Antibody for Promoting Myelin Repair in Multiple Sclerosis”.  Conrad Hilton Foundation, 11/04-11/07.  Principal Investigator, Moses Rodriguez.
• “Mechanism of Axonal Loss in Multiple Sclerosis”.  Donald and Frances Herdrich Foundation, 11/04-11/09.  Principal Investigator, Moses Rodriguez.
• “Remyelination in Multiple Sclerosis: Neural Precursor- Based Repair.” Canadian Multiple Sclerosis Society. 7/05-6/08. Principal Investigator, Moses Rodriguez.
• “Mayo Pediatric MS Center of Excellence,” National Multiple Sclerosis Society (01/06 – 12/09), Nancy Kuntz, Principal Investigator; Moses Rodriguez, Co-investigator.
• “Mayo Pediatric MS Center of Excellence,” National Multiple Sclerosis Society (01/10-3/13), Marc Patterson, Principal Investigator; Moses Rodriguez, Co-investigator.
• “Aspirin for the treatment of MS related fatigue,” National Multiple Sclerosis Society, RG 3808-A1 (10/06 – 10/09), Dean Wingerchuk, Principal Investigator; Moses Rodriguez, Co-investigator.
• “Non-Ambulatory Impairment in Benign Multiple Sclerosis,” National Multiple Sclerosis Society (01/07-12/10), Orhun Kantarci, Principal Investigator; Moses Rodriguez, Co-investigator.
• “Effect of Statins on Central Nervous System Remyelination,” National Multiple Sclerosis Society PP 1391 (03/07-02/08); Principal Investigator, Moses Rodriguez.
• “Mayo Rehabilitation Research Training Center,” National Institutes of Health, HD07447. Dr. Jeffrey Basford, Principal Investigator; Moses Rodriguez, Co-investigator.
• “Role of HLA Class II Genes in Demyelination,” National Institutes of Health, NS52173 (04/01/06-03/31/10;09/2/10 – 07/31/15). Dr. Chella David, Principal Investigator; Moses Rodriguez, Co-Investigator.
• “Genetic Analysis of Spontaneous Remyelination” National Institutes of Health, R01- NS048357   (04/01-08-03/31/12) Principal Investigator: Dr. Allan J. Bieber; Moses Rodriguez, Co-Investigator.
• “Role of CD8+ T cells in the formation of T1 black holes in animal model of MS,” National Institutes of Health, NS 58698 (04/01/08-03/31/12) Principal Investigator: Dr. Istvan Pirko; Moses Rodriguez, collaborator.
• “High-Resolution Nano-LAMP Microarrays to Measure the Binding Strength of Therapeutic Human Natural Auto-Antibodies on Target Cell-Surface Antigens,” Minnesota Partnership for Biotechnology and Medical Genomics # 08-10; (01/01/09 – 12/31/11) Co-Principal Investigators: Moses Rodriguez and Sang-Hyun Oh.
• “Therapeutic efficacy of metformin in the disease process of EAE,” National Institutes of Health, R21 NS065928, (05/01/10-3/31/12); Principal Investigator: Dr Ashutosh Mangalam; Moses Rodriguez, Co-investigator.
• “Microfluidic Neurotechnology for Neuronal Survival and Regeneration,” Minnesota Partnership for Biotechnology and Medical Genomics # 08-10; (02/01/11-01/31-13) Co-Principal Investigators: Moses Rodriguez and Sang-Hyun Oh.
• “Commensal gut-derived anaerobes as novel therapy for inflammatory autoimmune diseases,” Department of Defense, W81XWH-10-1-0254, (09/01/10-08/31/13); Principal Investigator: Dr. Shailendra Giri; Moses Rodriguez, Co-investigator.
•  “Nanopore Biosensor for Kinetics of Reparative Antibodies on Plasma Membranes,” National Institutes of Health, R01- GM092993, (06/01/10-05/31/14); Co-Principal Investigators: Moses Rodriguez and Sang-Hyun Oh.
• “Clinical Translation of a Neuron Protective Recombinant Human Antibody” National Institutes of Health, R21 NS073684, (04/01/11-03/31/13); Principal Investigator: Moses Rodriguez.
• “Genetic-Epigenetic Determinants of Recovery from Demyelinating Attacks in Humans: A Study of the MHC region” European Regional Development Fund FNUSA-ICRC .1.05/1.1.00/02.0123) (01/11-12/31/15); Co-investigator: Moses Rodriguez.
• “DNA Aptamers to induce remyelination in multiple sclerosis” NIH Relief NS78622-01, (01/01/12-12/31/13); Co-investigator: Moses Rodriguez
• “Treatment of Viral Infections with inhibitory viral RNA-dependent RNA-polymerase virus” HIPFA Discovery/Translation Award (01/01/10-12/31/12); Principal investigator: Moses Rodriguez.
• Applebaum MS Research Grant (01/01/07-12/30/12); Principal investigator: Moses Rodriguez.
• “Good Manufacturing Practices to Treat MS & Human Demyelinating Diseases” Mayo Discovery and Innovation Award (12/01/11-12/31/14); Principal investigator: Moses Rodriguez
• Hilton Fund for Multiple Sclerosis (10/1/08-9/30/12); Principal investigator: Moses Rodriguez
• “Novel Treatment of a Mouse ALS Model Using Neuron-protective Monoclonal Antibodies” Mayo Small Grants Program (11/01/12-12/31/13); Principal investigator: Moses Rodriguez
• “Natural Autoantibody-mediated Microcontact Printing” Novel Methodology Development Award (08/01/12-07/31/13); Principal investigator: Moses Rodriguez
• “Elucidating the role of radial glial progenitors in neonatal and pediatric white matter disease.”
  T. Denny Sanford Pediatric Collaborative Research Fund (06/01/12-05/31/14); Co-investigator: Moses Rodriguez.
• “Treatment of periventricular leukomalacia with recombinant, central nervous system-specific human monoclonal antibodies” CTSA Scholarly Opportunity Award (01/01/13-12/31/13; Co-investigator: Moses Rodriguez.